2025
Association of lifestyle factors and pathological characteristics in patients with early breast cancer and overweight/obesity: Results from the Breast Cancer Weight Loss (BWEL) trial.
Sposetti C, Ballman K, McCall L, Goodwin P, Weiss A, Thomson C, Hahn O, Hershman D, Paskett E, Minasian L, Nebeling L, Mayer E, Hopkins J, Bernstein V, Stearns V, White J, Winer E, Partridge A, Carey L, Ligibel J. Association of lifestyle factors and pathological characteristics in patients with early breast cancer and overweight/obesity: Results from the Breast Cancer Weight Loss (BWEL) trial. Journal Of Clinical Oncology 2025, 43: 561-561. DOI: 10.1200/jco.2025.43.16_suppl.561.Peer-Reviewed Original ResearchHEI scoresModerate/vigorous PAPhysical activityLifestyle factorsMenopausal statusDiet qualityAssociation of lifestyle factorsBreast cancerAssociated with breast cancerAssessment of PAHealthy Eating IndexProgesterone receptorHigher diet qualityWeight loss interventionBody mass indexEating IndexEstrogen receptorHealthier dietsLinear regression modelsDiagnosis to enrollmentOlder womenMass indexPhase III trialsEarly breast cancerMin/wkInfluences of Gender-Based Stigma on HIV Prevention and Care Among Older Women: A Scoping Review.
Vu T, Manalel J, Shourya S, Takenaka B, Monin J. Influences of Gender-Based Stigma on HIV Prevention and Care Among Older Women: A Scoping Review. Journal Of The Association Of Nurses In AIDS Care 2025 PMID: 40315459, DOI: 10.1097/jnc.0000000000000551.Peer-Reviewed Original ResearchGender-based stigmaHIV preventionOlder womenPublic health practiceIntimate partner violenceWell-being outcomesCaregiving roleHealth practicesScoping ReviewHIV statusHIV-relatedPartner violenceSystematic searchHIV researchSex practicesRelationship powerHIVStigmaSocietal levelWomenPreventionCaregiversOlderCareResearch findingsAssociations Between Internalized HIV Stigma and Cognitive Function Among Older Women With HIV
Vu T, Wise J, Jones D, Wingood G, Diaz M, Chandran A, Cohen M, Weiser S, Spence A, Wilson T, Norcini-Pala A, Sharma A, Rubin L, Turan B, Turan J, Monin J. Associations Between Internalized HIV Stigma and Cognitive Function Among Older Women With HIV. The Journals Of Gerontology Series B 2025, 80: gbaf058. PMID: 40123355, PMCID: PMC12067073, DOI: 10.1093/geronb/gbaf058.Peer-Reviewed Original ResearchConceptsInternalized HIV stigmaHIV stigmaAssociated with poorer global cognitive functionCognitive functionHIV Stigma ScalePoorer global cognitive functionStigma reduction interventionsAnnual incomeBenefit cognitive functionDomain-specific scoresFine motor functionGlobal cognitive scoreNonprescription drug useGlobal cognitive functionWomen's Interagency HIV StudyStigma ScaleMental healthReduction interventionsDepressive symptomsLinear regression modelsOlder womenWomen ageStigmaCognitive AssessmentAlcohol useCauses of embryo implantation failure: A systematic review and metaanalysis of procedures to increase embryo implantation potential
Bulletti F, Sciorio R, Conforti A, De Luca R, Bulletti C, Palagiano A, Berrettini M, Scaravelli G, Pierson R. Causes of embryo implantation failure: A systematic review and metaanalysis of procedures to increase embryo implantation potential. Frontiers In Endocrinology 2025, 15: 1429193. PMID: 40028443, PMCID: PMC11867936, DOI: 10.3389/fendo.2024.1429193.Peer-Reviewed Original ResearchConceptsAssisted Reproductive TechnologyPGT-AImplantation rateImplant successEmbryo transferEndometrial receptivityMeta-analysisMeta-analysis of subgroupsTime of endometrial receptivityGestational carrierMonths of unprotected sexual intercourseReduced embryo implantationPreimplantation genetic testingOlder womenImprove implantation ratesEmbryo implantation potentialUnprotected sexual intercourseOdds of implantationSystematic reviewComprehensive literature searchEmbryo euploidyEuploid embryosDiagnostic hysteroscopyRisk of biasIVF-ETSalidroside Improves Oocyte Competence of Reproductively Old Mice by Enhancing Mitophagy
Gu J, Hua R, Wu H, Guo C, Hai Z, Xiao Y, Yeung W, Liu K, Babayev E, Wang T. Salidroside Improves Oocyte Competence of Reproductively Old Mice by Enhancing Mitophagy. Aging Cell 2025, 24: e14475. PMID: 39789811, PMCID: PMC12073897, DOI: 10.1111/acel.14475.Peer-Reviewed Original ResearchReproductively old miceImprove oocyte qualityOocyte qualityOld miceDecline of oocyte qualityDevelopmental competence of oocytesReproductively older womenCompetence of oocytesKnowledge of therapeutic optionsOocyte competenceDevelopmental competenceTherapeutic optionsMaternal ageSpindle/chromosome structureAssisted reproductionOld femaleMiceOocytesOlder womenNatural fertilityFemale fertilityMitochondrial functionBridging Care Gaps for Older Women Undergoing Percutaneous Coronary Intervention
Kalra K, Sampath R, Cigarroa N, Sutton N, Damluji A, Nanna M. Bridging Care Gaps for Older Women Undergoing Percutaneous Coronary Intervention. Interventional Cardiology Clinics 2025, 14: 69-79. PMID: 39537289, PMCID: PMC11851336, DOI: 10.1016/j.iccl.2024.08.006.Peer-Reviewed Original Research
2024
Understanding risk factors for endometrial cancer in young women
Peeri N, Bertrand K, Na R, De Vivo I, Setiawan V, Seshan V, Alemany L, Chen Y, Clarke M, Clendenen T, Cook L, Costas L, Dal Maso L, Freudenheim J, Friedenreich C, Gierach G, Goodman M, La Vecchia C, Levi F, Lopez-Querol M, Lu L, Moysich K, Mutter G, Naduparambil J, Negri E, O’Connell K, O’Mara T, Palmer J, Parazzini F, Penney K, Petruzella S, Reynolds P, Ricceri F, Risch H, Rohan T, Sacerdote C, Sandin S, Shu X, Stolzenberg-Solomon R, Webb P, Wentzensen N, Wilkens L, Xu W, Yu H, Zeleniuch-Jacquotte A, Zheng W, Guo X, Lipworth L, Du M. Understanding risk factors for endometrial cancer in young women. Journal Of The National Cancer Institute 2024, 117: 76-88. PMID: 39235934, PMCID: PMC11717423, DOI: 10.1093/jnci/djae210.Peer-Reviewed Original ResearchRisk factorsEpidemiology of Endometrial Cancer ConsortiumEC riskOdds ratioOlder womenAverage risk womenKnowledge of risk factorsConfidence intervalsPopulation attributable fractionEstimate odds ratiosInverse association with ageYoung womenAmerican Cancer SocietyAssociated with reduced riskIncreased riskEndometrial cancerUnderstanding risk factorsEC risk factorsOral contraceptive useAttributable fractionRisk womenCurrent smokingCancer ConsortiumCancer SocietyAssociated with ageHelping ourselves, helping others: the Young Women’s Breast Cancer Study (YWS) – a multisite prospective cohort study to advance the understanding of breast cancer diagnosed in women aged 40 years and younger
Rosenberg S, Zheng Y, Ruddy K, Poorvu P, Snow C, Kirkner G, Meyer M, Tamimi R, Schapira L, Peppercorn J, Come S, Borges V, Warner E, Gelber S, Collins L, Winer E, Partridge A. Helping ourselves, helping others: the Young Women’s Breast Cancer Study (YWS) – a multisite prospective cohort study to advance the understanding of breast cancer diagnosed in women aged 40 years and younger. BMJ Open 2024, 14: e081157. PMID: 38951008, PMCID: PMC11218027, DOI: 10.1136/bmjopen-2023-081157.Peer-Reviewed Original ResearchConceptsYoung Women's Breast Cancer StudyMultisite prospective cohort studyBreast Cancer StudyProspective cohort studyStage 0-IV breast cancerBreast cancerCohort studyOlder womenDied of breast cancerFear of recurrencePatient-reported outcome dataYoung womenCancer studiesClinical data abstractionPost-traumatic stressQuality of lifeImprove careFollow-upPsychosocial outcomesYoung survivorsCommunity sitesBiospecimen collectionUnderstudied populationData abstractionOutcome dataFunctional decline in older breast cancer survivors treated with and without chemotherapy and non-cancer controls: results from the Hurria Older PatiEnts (HOPE) prospective study
Sedrak M, Sun C, Bae M, Freedman R, Magnuson A, O’Connor T, Moy B, Wildes T, Klepin H, Chapman A, Tew W, Dotan E, Fenton M, Kim H, Katheria V, Muss H, Cohen H, Gross C, Ji J. Functional decline in older breast cancer survivors treated with and without chemotherapy and non-cancer controls: results from the Hurria Older PatiEnts (HOPE) prospective study. Journal Of Cancer Survivorship 2024, 18: 1131-1143. PMID: 38678525, PMCID: PMC11324395, DOI: 10.1007/s11764-024-01594-3.Peer-Reviewed Original ResearchEarly-stage breast cancerPF-10 scorePF-10Physical functionNon-cancer controlsFunctional declineBC controlOlder breast cancer survivorsRAND 36-Item Short FormBreast cancerCohort of older adultsOlder womenBreast cancer survivorsImprove health outcomesPhysical function subscalePhysical function declineAccelerated functional declineBreast Cancer StudyCancer survivorsFunction subscaleHealth outcomesGroup of womenOlder adultsControl groupShort formEvaluating ChatGPT's accuracy in providing screening mammography recommendations among older women: Artificial Intelligence and cancer communication
Braithwaite D, Karanth S, Divaker J, Shoenborn N, Lin K, Richman I, Hochhegger B, O'Neill S, Schonberg M. Evaluating ChatGPT's accuracy in providing screening mammography recommendations among older women: Artificial Intelligence and cancer communication. Journal Of The American Geriatrics Society 2024, 72: 2237-2240. PMID: 38485652, DOI: 10.1111/jgs.18854.Peer-Reviewed Original ResearchEstimating Breast Cancer Overdiagnosis After Screening Mammography Among Older Women in the United States.
Richman I, Gross C. Estimating Breast Cancer Overdiagnosis After Screening Mammography Among Older Women in the United States. Annals Of Internal Medicine 2024, 177: 403-404. PMID: 38498894, DOI: 10.7326/l23-0485.Peer-Reviewed Original ResearchGender-based stigma and the prevention and treatment of HIV/AIDS among older women: A scoping review protocol
Vu T, Manalel J, Nyhan K, Wang K, Monin J. Gender-based stigma and the prevention and treatment of HIV/AIDS among older women: A scoping review protocol. PLOS ONE 2024, 19: e0298024. PMID: 38330082, PMCID: PMC10852273, DOI: 10.1371/journal.pone.0298024.Peer-Reviewed Original ResearchConceptsGender-based stigmaFull-text articlesOlder womenHIV preventionHIV care engagementStandardized data collection formPreferred Reporting ItemsImprove quality of lifeData collection formManagement of HIVPopulation of womenQuality of lifePeer-reviewed publicationsCare engagementCare experiencesWeb of ScienceTreatment of HIV/AIDSHealthcare providersNarrative summaryPRISMA-ScRSupplementary screeningSynthesize evidenceReporting ItemsCitation chainingCollection form‘If I don’t take care of me, then I can’t be there for others:’ a qualitative study of caregiving relationships among older women living with HIV
Vu T, Quinn M, Womack J, Monin J. ‘If I don’t take care of me, then I can’t be there for others:’ a qualitative study of caregiving relationships among older women living with HIV. Aging & Mental Health 2024, 28: 1304-1315. PMID: 38327025, DOI: 10.1080/13607863.2024.2313729.Peer-Reviewed Original ResearchCare networkHIV managementOlder womenPublic health programsCommunity-based organizationsPopulation of womenCare recipientsHealthcare discussionsOWLHHealth programsThematic analysisParticipants 1Qualitative studyCaregiversSemi-structuredCareEducational effortsHIVSources of meaningWomenParticipantsPerformance contentHealthcareYearsHealthAddition of rapamycin or co-culture with cumulus cells from younger reproductive age women does not improve rescue in vitro oocyte maturation or euploidy rates in older reproductive age women
Esbert M, Tao X, Ballesteros A, Yildirim R, Scott R, Seli E. Addition of rapamycin or co-culture with cumulus cells from younger reproductive age women does not improve rescue in vitro oocyte maturation or euploidy rates in older reproductive age women. Molecular Human Reproduction 2024, 30: gaad048. PMID: 38180884, DOI: 10.1093/molehr/gaad048.Peer-Reviewed Original ResearchReproductive-age womenEuploidy rateCumulus cellsAutologous cumulus cellsAge womenReproductive ageRescue IVMOlder womenYoung donorsYoung reproductive age womenYoung womenOlder reproductive age womenOocyte maturationMetaphase II oocytesGerminal vesicle stage oocytesPolar bodyMaternal ageEuploid oocytesFirst polar bodyAddition of rapamycinHours of cultureII oocytesWomenCytogenetic constitutionRapamycin
2023
Stereotactic Radiosurgery for Women Older than 65 with Breast Cancer Brain Metastases
Upadhyay R, Klamer B, Perlow H, White J, Bazan J, Jhawar S, Blakaj D, Grecula J, Arnett A, Mestres-Villanueva M, Healy E, Thomas E, Chakravarti A, Raval R, Lustberg M, Williams N, Palmer J, Beyer S. Stereotactic Radiosurgery for Women Older than 65 with Breast Cancer Brain Metastases. Cancers 2023, 16: 137. PMID: 38201564, PMCID: PMC10778270, DOI: 10.3390/cancers16010137.Peer-Reviewed Original ResearchIntracranial progression-free survivalProgression-free survivalBreast cancer patientsBrain metastasesOverall survivalYounger patientsCancer patientsRadiation necrosisOlder womenOlder patientsPositive diseaseSystemic therapyMultivariable analysisTreatment patternsBiopsy-proven breast cancer patientsCox proportional hazards regression methodsIncidence of BMOlder breast cancer patientsSingle-institutional retrospective reviewTreatment-related adverse eventsAge groupsBreast cancer brain metastasesMetastatic breast cancer patientsWorse progression-free survivalProportional hazards regression methodsEMPOWERING AND ADDRESSING AGE-RELATED CONCERNS AMONG OLDER WOMEN LIVING WITH HIV
Vu T, Quinn M, Valeika S, Monin J. EMPOWERING AND ADDRESSING AGE-RELATED CONCERNS AMONG OLDER WOMEN LIVING WITH HIV. Innovation In Aging 2023, 7: 136-136. PMCID: PMC10736168, DOI: 10.1093/geroni/igad104.0446.Peer-Reviewed Original ResearchSelf-CareOlder womenCommunity support groupsUnique psychosocial challengesGrounded theory approachOne-on-oneIn-depth phone interviewsCare journeyHIV stigmaInternalized stigmaTranscribed verbatimCaregiver networkOWLHPsychosocial challengesCaregiving responsibilitiesHIV preventionSupport groupsLong-term effects of treatmentHIV clinicPhone interviewsPhysical burdenQualitative studyPsychosocial stressorsThematic codingStructural interventionsPrevalence of targetable genomic alterations in young women with advanced breast cancer: a cross-sectional study
Blansky D, Ansari N, Gao L, Sokol E, Sivakumar S, Huang R, Pelletier M, Levy M, Pavlick D, Danziger N, Ross J, Lustberg M, Rozenblit M. Prevalence of targetable genomic alterations in young women with advanced breast cancer: a cross-sectional study. Breast Cancer Research And Treatment 2023, 204: 181-185. PMID: 37999916, DOI: 10.1007/s10549-023-07179-5.Peer-Reviewed Original ResearchComprehensive genomic profilingBreast cancerYoung womenGenomic alterationsAdvanced breast cancerPD-L1 expressionTargetable genomic alterationsWorse clinical outcomesTime of diagnosisTumor mutational burdenCross-sectional studyBreast cancer casesFoundation MedicineClinical outcomesPIK3CA mutationsCancer casesEstrogen receptorMutational burdenOlder womenConclusionOur findingsTotal casesBreast tumorsTumor tissueBRCA1 mutationsMicrosatellite instabilityAssociation between F2-Isoprostane Metabolites and Weight Change in Older Women: A Longitudinal Analysis
Zhao Y, Nogueira M, Chen Q, Dai Q, Cai Q, Wen W, Lan Q, Rothman N, Gao Y, Shu X, Zheng W, Milne G, Yang G. Association between F2-Isoprostane Metabolites and Weight Change in Older Women: A Longitudinal Analysis. Gerontology 2023, 70: 134-142. PMID: 37967546, PMCID: PMC10922451, DOI: 10.1159/000534258.Peer-Reviewed Original ResearchConceptsF2-IsoP-MAssociated with subsequent weight lossOlder womenMeasures of anthropometryWeight changeF2-IsoPsIncreased all-cause mortalityF2-isoprostanesWeight lossFollow-upLowest quartile groupProspective cohort studyAll-Cause MortalityPhysical activityDetermination of body weightProlonged follow-upTime-varying covariatesLinear mixed-effects modelsFollow-up periodInverse associationLongitudinal associationsPercentage of weight changeHealth issuesCohort studyMiddle-agedFalls prechemotherapy and toxicity‐related hospitalization during adjuvant chemotherapy for breast cancer in older women: Results from the prospective multicenter HOPE trial
Ji J, Bae M, Sun C, Wildes T, Freedman R, Magnuson A, O'Connor T, Moy B, Klepin H, Chapman A, Tew W, Dotan E, Fenton M, Kim H, Katheria V, Gross C, Cohen H, Muss H, Sedrak M. Falls prechemotherapy and toxicity‐related hospitalization during adjuvant chemotherapy for breast cancer in older women: Results from the prospective multicenter HOPE trial. Cancer 2023, 130: 936-946. PMID: 37962093, PMCID: PMC10922500, DOI: 10.1002/cncr.35105.Peer-Reviewed Original ResearchToxicity-related hospitalizationAdjuvant chemotherapyBreast cancerOlder womenPrimary end pointEarly breast cancerMultivariable logistic regressionGeriatric characteristicsGeriatric covariatesHOPE trialIncident hospitalizationGeriatric assessmentProspective studyGeriatric factorsHospitalizationChemotherapyGreater oddsStage IOlder personsEnd pointCancerLogistic regressionCategorical variablesWomenDiseaseValidation of the European SCORE2 models in a Canadian primary care cohort
Sud M, Sivaswamy A, Austin P, Abdel-Qadir H, Anderson T, Khera R, Naimark D, Lee D, Roifman I, Thanassoulis G, Tu K, Wijeysundera H, Ko D. Validation of the European SCORE2 models in a Canadian primary care cohort. European Journal Of Preventive Cardiology 2023, 31: 668-676. PMID: 37946603, PMCID: PMC11025037, DOI: 10.1093/eurjpc/zwad352.Peer-Reviewed Original ResearchPrimary care cohortAtherosclerotic cardiovascular diseaseLow-risk regionsCare cohortC-statisticOlder personsElectronic medical record dataLarge Canadian cohortMedical record dataYears of ageYoung personASCVD riskCanadian cohortCardiovascular diseaseOlder womenIndividuals 70Age groupsSCORE2CohortRecord dataWomenMenRiskPersonsDisease
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