2025
The Epidemiology and Mechanisms of Pediatric Facial Fractures
Hu K, Parikh N, Allam O, Wasserburg J, Perez P, Rancu A, Ihnat J, Aral A, Alperovich M. The Epidemiology and Mechanisms of Pediatric Facial Fractures. Journal Of Craniofacial Surgery 2025, 36: 1543-1546. PMID: 40029053, DOI: 10.1097/scs.0000000000011163.Peer-Reviewed Original ResearchTrauma Quality Improvement ProjectPediatric facial fracturesFacial fracturesInjury mechanismAge-specific prevention strategiesHigh-energy injury mechanismsChild safety measuresSkull vault fracturesQuality improvement projectFirearm-related injuriesComprehensive national studyPrimary injury mechanismHigh-energy mechanismsMotor vehicle accidentsPublic health officialsPatients aged 0In-hospital mortality ratePediatric patients aged 0Older childrenNasal bone fracturesSustained facial fracturesImprovement projectCharacteristics of childrenComprehensive cohortSource of morbidity
2024
Protocol for the Catheter-Related Early Thromboprophylaxis With Enoxaparin (CRETE) Studies
Faustino E, Kandil S, Leroue M, Sochet A, Kong M, Cholette J, Nellis M, Pinto M, Chegondi M, Ramirez M, Schreiber H, Kerris E, Glau C, Kolmar A, Muisyo T, Sharathkumar A, Polikoff L, Silva C, Ehrlich L, Navarro O, Spinella P, Raffini L, Taylor S, McPartland T, Shabanova V, Network F. Protocol for the Catheter-Related Early Thromboprophylaxis With Enoxaparin (CRETE) Studies. Pediatric Critical Care Medicine 2024, 26: e95-e105. PMID: 39560771, PMCID: PMC11717624, DOI: 10.1097/pcc.0000000000003648.Peer-Reviewed Original ResearchRandomized clinical trialsDose of enoxaparinCatheter-relatedEarly thromboprophylaxisHigher risk of clinically relevant bleedingRisk of clinically relevant bleedingProphylactic doses of enoxaparinTherapeutic dose of enoxaparinOlder childrenMarkers of thrombin generationClinically Relevant BleedingEfficacy of prophylaxisDeep venous thrombosisRemoval of CVCsCritically Ill ChildrenPlatelet-poor plasmaPost Hoc AnalysisGestational ageInternational unitsInstitutional review boardRelevant bleedingProphylactic doseUsual careAge-dependent heterogeneityVenous thrombosisSchool-age children are more skeptical of inaccurate robots than adults
Flanagan T, Georgiou N, Scassellati B, Kushnir T. School-age children are more skeptical of inaccurate robots than adults. Cognition 2024, 249: 105814. PMID: 38763071, DOI: 10.1016/j.cognition.2024.105814.Peer-Reviewed Original ResearchCross-modal plasticity in children with cochlear implant: converging evidence from EEG and functional near-infrared spectroscopy
Deroche M, Wolfe J, Neumann S, Manning J, Hanna L, Towler W, Wilson C, Bien A, Miller S, Schafer E, Gemignani J, Alemi R, Muthuraman M, Koirala N, Gracco V. Cross-modal plasticity in children with cochlear implant: converging evidence from EEG and functional near-infrared spectroscopy. Brain Communications 2024, 6: fcae175. PMID: 38846536, PMCID: PMC11154148, DOI: 10.1093/braincomms/fcae175.Peer-Reviewed Original ResearchCochlear implantationImplanted childrenCross-modal reorganizationYear old childrenAuditory association areasFunctional Near-Infrared SpectroscopyCross-modal plasticitySilent worldNear-infrared spectroscopyVisual cortex responsesAuditory cortexCortical responsesOlder childrenResponse to environmental stimulationPromote visionsChildrenHigh-density electroencephalographyImplantationCortex responsesLow-level visual tasksVisual cortexHearingCortexAssociation areasLanguage abilityOlfactory training improves emotion matching ability in 6–9 years old children — preliminary evidence
Pieniak M, Rokosz M, Ivcevic Z, Reichert A, Żyżelewicz B, Nawrocka P, Lebuda I, Oleszkiewicz A. Olfactory training improves emotion matching ability in 6–9 years old children — preliminary evidence. Journal Of Sensory Studies 2024, 39 DOI: 10.1111/joss.12912.Peer-Reviewed Original ResearchEmotional facial expressionsEmotion knowledgeOlfactory stimulationFacial expressionsEmotion knowledge deficitsProcess olfactory stimuliEmotional processingEighty-three childrenNeural substratesOdorless stimuliPlacebo groupOlfactory stimuliOT groupExpressed EmotionEmotional developmentYear old childrenEmotionsPreliminary evidenceBaseline scoresMatching abilityOlder childrenRecent findingsAged 6StimuliChildrenCholera toxin and O-specific polysaccharide immune responses after oral cholera vaccination with Dukoral in different age groups of Bangladeshi participants
Dash P, Hakim A, Akter A, Banna H, Kaisar M, Aktar A, Jahan S, Ferdous J, Basher S, Kamruzzaman M, Chowdhury F, Akter A, Tauheed I, Weil A, Charles R, Calderwood S, Ryan E, LaRocque R, Harris J, Bhuiyan T, Qadri F. Cholera toxin and O-specific polysaccharide immune responses after oral cholera vaccination with Dukoral in different age groups of Bangladeshi participants. MSphere 2024, 9: e00565-23. PMID: 38391226, PMCID: PMC10964428, DOI: 10.1128/msphere.00565-23.Peer-Reviewed Original ResearchB cell responsesMemory B cell responsesClass-switched antibody responsesOral cholera vaccineAntibody responseImmune responseCholera toxin B subunitCholera vaccineToxin B subunitAge groupsAnti-OSPOlder childrenPrevent choleraIgG antibody responsesYoung childrenB subunitVaccine seriesSignificant IgAIgM responseWhole-cellOlder vaccineesCholera toxinIgAVaccineIgG
2023
The Selective Social Attention task in children with autism spectrum disorder: Results from the Autism Biomarkers Consortium for Clinical Trials (ABC‐CT) feasibility study
Shic F, Barney E, Naples A, Dommer K, Chang S, Li B, McAllister T, Atyabi A, Wang Q, Bernier R, Dawson G, Dziura J, Faja S, Jeste S, Murias M, Johnson S, Sabatos‐DeVito M, Helleman G, Senturk D, Sugar C, Webb S, McPartland J, Chawarska K, Trials T. The Selective Social Attention task in children with autism spectrum disorder: Results from the Autism Biomarkers Consortium for Clinical Trials (ABC‐CT) feasibility study. Autism Research 2023, 16: 2150-2159. PMID: 37749934, PMCID: PMC11003770, DOI: 10.1002/aur.3026.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSocial attention taskSchool-aged childrenAttention taskASD groupSpectrum disorderEye-tracking taskTotal T-scoreAttentional patternsAutism spectrumTD groupPresentation timeTrial feasibility studyGroup differencesPercent of timeOlder childrenTaskComparison groupToddlersT-scoreChildrenChildren 4Outcome variablesFaceCondition effectsOut-of-pocket costs and catastrophic healthcare expenditure for families of children requiring surgery in sub-Saharan Africa
Yap A, Olatunji B, Negash S, Mweru D, Kisembo S, Masumbuko F, Ameh E, Lebbie A, Bvulani B, Hansen E, Philipo G, Carroll M, Hsu P, Bryce E, Cheung M, Fedatto M, Laverde R, Ozgediz D. Out-of-pocket costs and catastrophic healthcare expenditure for families of children requiring surgery in sub-Saharan Africa. Surgery 2023, 174: 567-573. PMID: 37385869, DOI: 10.1016/j.surg.2023.05.010.Peer-Reviewed Original ResearchConceptsCatastrophic healthcare expenditureFamilies of childrenHealthcare expendituresChildren's surgeryPocket costsPediatric surgical patientsMultivariate logistic regressionPediatric operating roomIntensive resource utilizationPocket healthcare costsUniversal healthcare coverageChart reviewSurgical patientsSubgroup analysisClinical dataAfrican hospitalsHealthcare costsEconomic burdenMedian annual incomeSurgeryOlder ageLogistic regressionHealthcare coverageOperating roomOlder childrenComparing Attention to Biological Motion in Autism across Age Groups Using Eye-Tracking
Hochhauser M, Dommer K, Atyabi A, Li B, Ahn Y, Aubertine M, Kim M, Corrigan S, Pelphrey K, Shic F. Comparing Attention to Biological Motion in Autism across Age Groups Using Eye-Tracking. 2023, 1-3. DOI: 10.1145/3588015.3590126.Peer-Reviewed Original ResearchAutism spectrum disorderNon-biological motionLocal motion cuesAttentional biasesBiological motionTD childrenDevelopmental advancesSpectrum disorderMotion cuesEye movementsOlder childrenChildrenPotential avenuesYounger groupFigure headBiasesMethodological analysisAutismCuesAge groupsDisordersAttentionDisplayPersonality Changes and Staring Spells in a 12-Year-Old Child: A Case Report Incorporating ChatGPT, a Natural Language Processing Tool Driven by Artificial Intelligence (AI)
Puthenpura V, Nadkarni S, DiLuna M, Hieftje K, Marks A. Personality Changes and Staring Spells in a 12-Year-Old Child: A Case Report Incorporating ChatGPT, a Natural Language Processing Tool Driven by Artificial Intelligence (AI). Cureus 2023, 15: e36408. PMID: 37090271, PMCID: PMC10115215, DOI: 10.7759/cureus.36408.Peer-Reviewed Original ResearchLow-grade gliomasIntracranial tumorsPersonality changesTreatment of LGGCentral nervous system tumorsMain presenting featuresBroad differential diagnosisNervous system tumorsPresenting featuresPediatric patientsCase reportSystem tumorsFavorable outcomeEndocrine conditionsMain symptomsDifferential diagnosisIntracranial neoplasmsBrain tumorsGrade gliomasEarly identificationSymptomsTumorsOlder childrenCommon typeNatural language processing tools
2022
Food-specific immunoglobulin A does not correlate with natural tolerance to peanut or egg allergens
Liu E, Zhang B, Martin V, Anthonypillai J, Kraft M, Grishin A, Grishina G, Catanzaro J, Chinthrajah S, Sindher T, Manohar M, Quake A, Nadeau K, Burks A, Kim E, Kulis M, Henning A, Jones S, Leung D, Sicherer S, Wood R, Yuan Q, Shreffler W, Sampson H, Shabanova V, Eisenbarth S. Food-specific immunoglobulin A does not correlate with natural tolerance to peanut or egg allergens. Science Translational Medicine 2022, 14: eabq0599. PMID: 36383680, PMCID: PMC10219469, DOI: 10.1126/scitranslmed.abq0599.Peer-Reviewed Original ResearchConceptsPeanut allergyFood allergyEpitope specificityPredominant antibody isotypePeanut-specific IgEDifferent epitope specificitiesSimilar epitope specificityAtopic childrenEgg allergyOral toleranceAllergic infantsImmune exclusionEgg toleranceAntibody isotypesImmunoglobulin ACommensal floraSeparate cohortAllergyEgg allergensInfant stoolHealthy adultsIgAProtective roleOlder childrenChildrenParent Stress and Trauma, Autonomic Responses, and Negative Child Behaviors
Fogelman N, Schwartz J, Chaplin TM, Jastreboff AM, Silverman WK, Sinha R. Parent Stress and Trauma, Autonomic Responses, and Negative Child Behaviors. Child Psychiatry & Human Development 2022, 54: 1779-1788. PMID: 35674991, PMCID: PMC9729425, DOI: 10.1007/s10578-022-01377-w.Peer-Reviewed Original ResearchConceptsNegative child behaviorsTraumatic life eventsParent stressChild behaviorLife eventsParent-child interactionsChild behavioral outcomesGreater heart rate variabilityRecent life eventsChildren's attentionBehavioral outcomesHeart rate variabilityPhysiological copingYear old childrenLife stressAggressive behaviorCumulative stressOlder childrenMore parentsInteraction challengesAutonomic responsesParentsMajor lifeMore childrenChildrenLong-Term Complications of COVID-19 Infection in Adolescents and Children
Thallapureddy K, Thallapureddy K, Zerda E, Suresh N, Kamat D, Rajasekaran K, Moreira A. Long-Term Complications of COVID-19 Infection in Adolescents and Children. Current Pediatrics Reports 2022, 10: 11-17. PMID: 35127274, PMCID: PMC8803461, DOI: 10.1007/s40124-021-00260-x.Peer-Reviewed Original ResearchLong COVIDSARS-CoV-2 infectionPersistent COVID-19 symptomsLong COVID-19Long COVID symptomsSymptomatic COVID-19COVID-19 infectionCOVID-19 symptomsHealth care providersCOVID-19Recent FindingsChildrenPersistent symptomsTerm complicationsPediatric populationCOVID symptomsCare providersSymptomsOlder childrenChildrenAdultsInfectionMore evidenceAdolescentsCOVIDPotential effects
2021
Epidemiology of wheeze among preschool children: a population-based cross-sectional study from rural Sri Lanka
Mudiyanselage S, Amarasiri WADL, Yasaratne BMGD, Warnasekara J, Agampodi S. Epidemiology of wheeze among preschool children: a population-based cross-sectional study from rural Sri Lanka. BMJ Open 2021, 11: e046688. PMID: 34233982, PMCID: PMC8264903, DOI: 10.1136/bmjopen-2020-046688.Peer-Reviewed Original ResearchConceptsIndependent risk factorCross-sectional studySevere wheezeAllergic rhinitisPassive smokingRisk factorsFrequent consumptionPopulation-based cross-sectional studyRural Sri LankaPreschool childrenPrevalence of wheezeWheezing attacksFrequent symptomsSevere wheezingMean ageYear old childrenChildhood questionnaireSevere episodesWheezeFemale childrenProtective factorsOlder childrenStudy sampleSize samplingAsthmaticsAge-Dependent Heterogeneity in the Efficacy of Prophylaxis With Enoxaparin Against Catheter-Associated Thrombosis in Critically Ill Children: A Post Hoc Analysis of a Bayesian Phase 2b Randomized Clinical Trial.
Faustino EVS, Raffini LJ, Hanson SJ, Cholette JM, Pinto MG, Li S, Kandil SB, Nellis ME, Shabanova V, Silva CT, Tala JA, McPartland T, Spinella PC. Age-Dependent Heterogeneity in the Efficacy of Prophylaxis With Enoxaparin Against Catheter-Associated Thrombosis in Critically Ill Children: A Post Hoc Analysis of a Bayesian Phase 2b Randomized Clinical Trial. Critical Care Medicine 2021, 49: e369-e380. PMID: 33566465, PMCID: PMC7979442, DOI: 10.1097/ccm.0000000000004848.Peer-Reviewed Original ResearchConceptsCentral venous catheter-associated deep venous thrombosisCatheter-associated deep venous thrombosisCentral venous cathetersEfficacy of prophylaxisDeep venous thrombosisAge-dependent heterogeneityAnti-Xa levelsVenous cathetersVenous thrombosisFactor VIII activityThrombin generationPlatelet countClinical trialsIll childrenPhase 2bVIII activityLow factor VIII activityCatheter-associated thrombosisInternational units/mLMinimum platelet countOlder childrenCritically Ill ChildrenEndogenous thrombin potentialHigher platelet countsPost Hoc Analysis
2019
Social Processes and Risk for Autism
Klaiman C, Saulnier C, Rubin E, Chawarska K, Klin A. Social Processes and Risk for Autism. 2019, 350-370. DOI: 10.1093/oxfordhb/9780199837182.013.15.Peer-Reviewed Original ResearchMeasuring Treatment Response in Pediatric Trichotillomania: A Meta-Analysis of Clinical Trials
Farhat LC, Olfson E, Levine JLS, Li F, Franklin ME, Lee HJ, Lewin AB, McGuire JF, Rahman O, Storch EA, Tolin DF, Zickgraf HF, Bloch MH. Measuring Treatment Response in Pediatric Trichotillomania: A Meta-Analysis of Clinical Trials. Journal Of Child And Adolescent Psychopharmacology 2019, 30: 306-315. PMID: 31794677, PMCID: PMC7476376, DOI: 10.1089/cap.2019.0103.Peer-Reviewed Original ResearchConceptsCut-pointsOptimal cut-pointMeta-analysisTreatment responseData-driven cut-pointsClinical trialsMGH-HPSMassachusetts General Hospital Hair Pulling ScaleDefinitions of treatment responseMeta-analysis of clinical trialsMeta-DiSc softwareParent versionObjectives:</i></b>Measure treatment responseChild versionSeverity ScalePooled accuracy measuresClinical responseMeta-DiscPediatric trichotillomaniaNational InstitutePediatric populationYouden indexOlder childrenYoung childrenPediatric Quality of Life Inventory (PedsQL) in Fragile X Syndrome
Fitzpatrick S, Schmitt L, Adams R, Pedapati E, Wink L, Shaffer R, Sage J, Weber J, Dominick K, Erickson C. Pediatric Quality of Life Inventory (PedsQL) in Fragile X Syndrome. Journal Of Autism And Developmental Disorders 2019, 50: 1056-1063. PMID: 31728808, PMCID: PMC7232688, DOI: 10.1007/s10803-019-04292-7.Peer-Reviewed Original ResearchIntroduction Assessment in Early Childhood
Stein R, Njoroge W, Dunn D. Introduction Assessment in Early Childhood. 2019, 1-20. DOI: 10.1007/978-3-030-10635-5_1.Peer-Reviewed Original ResearchAngiopoietin Level Trajectories in Toddlers With Severe Sepsis and Septic Shock and Their Effect on Capillary Endothelium
Pierce RW, Shabanova V, Canarie M, Pinto M, da Silva YS, Bhandari V, Giuliano JS. Angiopoietin Level Trajectories in Toddlers With Severe Sepsis and Septic Shock and Their Effect on Capillary Endothelium. Shock 2019, 51: 298-305. PMID: 30286031, PMCID: PMC6375782, DOI: 10.1097/shk.0000000000001172.Peer-Reviewed Original ResearchConceptsSevere sepsis/septic shockSepsis/septic shockTumor necrosis factorHuman dermal microvascular endothelial cellsCultured human dermal microvascular endothelial cellsSIRS/sepsisSeptic shockAngpt-1Severe sepsisAngpt-2Diagnostic biomarkersSevere sepsis/shockTertiary care pediatric hospitalEndothelial cellsAngpt-2 levelsOlder childrenSepsis/shockInflammatory response syndromeProspective observational studyTransendothelial electrical resistance measurementsDermal microvascular endothelial cellsAppropriate diagnostic biomarkersMicrovascular endothelial cellsYoung childrenEnzyme-linked immunoassay
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