2024
Ten years of research on the treatments of internet gaming disorder: A scoping review and directions for future research
Dong G, Dai J, Potenza M. Ten years of research on the treatments of internet gaming disorder: A scoping review and directions for future research. Journal Of Behavioral Addictions 2024, 13: 51-65. PMID: 38183434, PMCID: PMC10988415, DOI: 10.1556/2006.2023.00071.Peer-Reviewed Original ResearchNon-invasive brain stimulationCognitive behavioral therapyTreatment strategiesTreatment studiesInternet gaming disorderMedication-based treatmentDifferent treatment strategiesStudies of treatmentTreatment of IGDFuture studiesBrain stimulationControl groupBehavioral therapyGaming disorderTreatmentDSM-5Sex differencesDisordersSummary of findingsCurrent studyEarly stagesPharmacotherapyTherapyStudyYearsAmygdala response to emotional faces following acute administration of psilocybin in healthy individuals
Armand S, Larsen K, Madsen M, Ozenne B, Preller K, Knudsen G, Stenbæk D, Fisher P. Amygdala response to emotional faces following acute administration of psilocybin in healthy individuals. Neuroscience Applied 2024, 3: 103934. DOI: 10.1016/j.nsa.2023.103934.Peer-Reviewed Original ResearchPlasma psilocin levelsFunctional magnetic resonance imagingAmygdala reactivityHealthy individualsAmygdala responseMagnetic resonance imagingAcute administrationDrug intensityAcute exposureTherapeutic outcomesResonance imagingSignificant associationBrain regionsPsychedelic psilocybinPsilocybinBaselineFuture studiesSignificant changesExposureFearful facesEmotion processingResponseIndividualsAdministration
2023
Application possibilities of artificial intelligence in facial vascularized composite allotransplantation—a narrative review
Knoedler L, Knoedler S, Allam O, Remy K, Miragall M, Safi A, Alfertshofer M, Pomahac B, Kauke-Navarro M. Application possibilities of artificial intelligence in facial vascularized composite allotransplantation—a narrative review. Frontiers In Surgery 2023, 10: 1266399. PMID: 38026484, PMCID: PMC10646214, DOI: 10.3389/fsurg.2023.1266399.Peer-Reviewed Original ResearchComposite allotransplantationLong-term outcomesFacial trauma patientsSevere facial disfigurementRejection episodesSurgical treatmentTrauma patientsMalignancy screeningReconstructive surgeryClinical challengeFacial traumaPaucity of studiesReconstructive strategiesNarrative reviewPatientsFacial disfigurementAllotransplantationFuture studiesSurgeryDiagnosisTraumaDisfigurementDistinguishing features of long COVID identified through immune profiling
Klein J, Wood J, Jaycox J, Dhodapkar R, Lu P, Gehlhausen J, Tabachnikova A, Greene K, Tabacof L, Malik A, Silva Monteiro V, Silva J, Kamath K, Zhang M, Dhal A, Ott I, Valle G, Peña-Hernández M, Mao T, Bhattacharjee B, Takahashi T, Lucas C, Song E, McCarthy D, Breyman E, Tosto-Mancuso J, Dai Y, Perotti E, Akduman K, Tzeng T, Xu L, Geraghty A, Monje M, Yildirim I, Shon J, Medzhitov R, Lutchmansingh D, Possick J, Kaminski N, Omer S, Krumholz H, Guan L, Dela Cruz C, van Dijk D, Ring A, Putrino D, Iwasaki A. Distinguishing features of long COVID identified through immune profiling. Nature 2023, 623: 139-148. PMID: 37748514, PMCID: PMC10620090, DOI: 10.1038/s41586-023-06651-y.Peer-Reviewed Original ResearchConceptsLong COVIDSARS-CoV-2Infection syndromeExaggerated humoral responseSoluble immune mediatorsEpstein-Barr virusPost-exertional malaiseCross-sectional studyHigher antibody responseImmune mediatorsImmune phenotypingImmune profilingHumoral responseAntibody responseLymphocyte populationsCOVID statusUnbiased machineCortisol levelsLC statusRelevant biomarkersViral pathogensSyndromeCOVIDFuture studiesBiological featuresInterim guidelines for the assessment and treatment of pain in children with multiple sclerosis
Stratton C, Vassilopoulos A, Brenton J, Potter K, Vargas W, Rumm H, Bartels A, Bailey M, Odonkor C, Stoll S, Zempsky E, Yeh E, Makhani N. Interim guidelines for the assessment and treatment of pain in children with multiple sclerosis. Frontiers In Neuroscience 2023, 17: 1235945. PMID: 37781253, PMCID: PMC10536169, DOI: 10.3389/fnins.2023.1235945.Peer-Reviewed Original ResearchMultiple sclerosisManagement of painTreatment of painAdvanced practice nursingInterdisciplinary management approachInterim guidelinesTreatment guidelinesPain assessmentTreatment recommendationsPainPractice nursingMS researchClinical settingAnonymous completionSclerosisChildrenDelphi panelFuture studiesSurvey themesGuidelinesComprehensive assessmentAssessmentPanel chairsPhysiotherapyPhysiatryVariation in Risk‐Standardized Acute Admission Rates Among Patients With Heart Failure in Accountable Care Organizations: Implications for Quality Measurement
Chuzi S, Lindenauer P, Faridi K, Priya A, Pekow P, D'Aunno T, Mazor K, Stefan M, Spatz E, Gilstrap L, Werner R, Lagu T. Variation in Risk‐Standardized Acute Admission Rates Among Patients With Heart Failure in Accountable Care Organizations: Implications for Quality Measurement. Journal Of The American Heart Association 2023, 12: e029758. PMID: 37345796, PMCID: PMC10356066, DOI: 10.1161/jaha.122.029758.Peer-Reviewed Original ResearchConceptsAcute admission ratesHeart failureMedicare Shared Savings Program Accountable Care OrganizationsAccountable care organizationsAdmission ratesMost ACOsPrimary care providersPerformance categoriesCare organizationsACO characteristicsHealth care qualityAdmission riskBlack beneficiariesCare providersMedicare feeService beneficiariesConclusions AdmissionCare qualityPatientsAdmissionHospital affiliationACO structureFuture studiesLower proportionFailureA novel defined pyroptosis-related gene signature predicts prognosis and correlates with the tumour immune microenvironment in lung adenocarcinoma
Chen Z, Ge L, Xu S, Li Q, Zhou L. A novel defined pyroptosis-related gene signature predicts prognosis and correlates with the tumour immune microenvironment in lung adenocarcinoma. Scientific Reports 2023, 13: 9921. PMID: 37337018, PMCID: PMC10279685, DOI: 10.1038/s41598-023-36720-1.Peer-Reviewed Original ResearchConceptsPyroptosis-related genesTumor-infiltrating immune cellsTumor mutational burdenLung adenocarcinomaImmune cellsMutational burdenPrognostic signaturePyroptosis-related gene signatureTumor microenvironmentGene Expression Omnibus (GEO) cohortSelection operator CoxImmune cell infiltrationRole of pyroptosisIndependent prognostic biomarkerTumor immune microenvironmentCox regression modelImmune checkpoint regulatorsCancer-related deathCancer Genome Atlas (TCGA) databaseSpearman correlation analysisFuture studiesImmune microenvironmentCell infiltrationLUAD patientsCommon causeEndometrial responses to bacterial and viral infection: a scoping review.
Lindsay C, Potter J, Grimshaw A, Abrahams V, Tong M. Endometrial responses to bacterial and viral infection: a scoping review. Human Reproduction Update 2023, 29: 675-693. PMID: 37290428, PMCID: PMC10477945, DOI: 10.1093/humupd/dmad013.Peer-Reviewed Original ResearchConceptsEndometrial responseViral infectionUterus/endometriumFull-text studiesInnate immune sensingInnate immune responseFree-text termsEmbase/MedlineIntrauterine infectionObstetric complicationsEndometrial productionCochrane LibraryFuture studiesImplantation failureNeisseria gonorrheaImmune cellsMost infectionsImmune responseUterine functionChlamydia trachomatisAnimal modelsImmune sensingEndometriumZika virusMajority of studiesDemystifying treatment disposition patterns for psychiatrically high-risk youth referred for intensive outpatient psychiatric services: The role of demographics and telehealth
Kruger M, Barnes S, Childs A. Demystifying treatment disposition patterns for psychiatrically high-risk youth referred for intensive outpatient psychiatric services: The role of demographics and telehealth. Clinical Child Psychology And Psychiatry 2023, 28: 1435-1448. PMID: 36932876, DOI: 10.1177/13591045231165191.Peer-Reviewed Original ResearchConceptsDisposition patternsTreatment modalitiesHigh-risk youthOutpatient psychiatric treatmentOutpatient psychiatric servicesClinical outcomesTreatment referralTreatment completionCare settingsTelehealth modalitiesMultinomial logistic regressionPsychiatric servicesTreatment dispositionPsychiatric treatmentLogistic regressionPerson servicesTelehealthModalitiesFuture studiesTreatmentCurrent studyReferralIOPPersonsCourseThe Role of B Cells in Skin Inflammation
Frank A, Belperron A, Bockenstedt L. The Role of B Cells in Skin Inflammation. Journal Of Student Research 2023, 11 DOI: 10.47611/jsr.v11i3.1684.Commentaries, Editorials and LettersNeuroinflammation in Obsessive-Compulsive Disorder Sydenham Chorea, Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections, and Pediatric Acute Onset Neuropsychiatric Syndrome
Vreeland A, Thienemann M, Cunningham M, Muscal E, Pittenger C, Frankovich J. Neuroinflammation in Obsessive-Compulsive Disorder Sydenham Chorea, Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections, and Pediatric Acute Onset Neuropsychiatric Syndrome. Psychiatric Clinics Of North America 2023, 46: 69-88. PMID: 36740356, DOI: 10.1016/j.psc.2022.11.004.Peer-Reviewed Original ResearchConceptsPediatric acute-onset neuropsychiatric syndromePediatric autoimmune neuropsychiatric disordersAutoimmune neuropsychiatric disordersSydenham's choreaStreptococcal infectionNeuroinflammatory diseasesNeuropsychiatric syndromeNeuropsychiatric disordersSource of inflammationObsessive-compulsive disorderRheumatological diseasesBasal gangliaClinical trialsClinical dataMajor manifestationsDiagnostic biomarkersImmune systemDisordersDiseaseBehavioral disordersInflammationChoreaSyndromeInfectionFuture studiesGender differences underlying the link between exposome and psychosis
Guloksuz S. Gender differences underlying the link between exposome and psychosis. European Psychiatry 2023, 66: s29-s30. PMCID: PMC10417599, DOI: 10.1192/j.eurpsy.2023.114.Peer-Reviewed Original ResearchGender-related differencesPsychosis riskChildhood adversitySubstance abuse comorbidityAssociation of psychosisObstetric complicationsDifferent symptom dimensionsSeason of birthHigh prevalencePsychotic disordersPubMed databaseSystematic reviewSubstance abusePsychosisSubstance useEnvironmental exposuresWomenUrban upbringingChildhood abuseSymptom dimensionsMenEarly ageRiskExposomeFuture studiesGenome-Wide Association Study Points to Novel Locus for Gilles de la Tourette Syndrome
Tsetsos F, Topaloudi A, Jain P, Yang Z, Yu D, Kolovos P, Tumer Z, Rizzo R, Hartmann A, Depienne C, Worbe Y, Müller-Vahl K, Cath D, Boomsma D, Wolanczyk T, Zekanowski C, Barta C, Nemoda Z, Tarnok Z, Padmanabhuni S, Buxbaum J, Grice D, Glennon J, Stefansson H, Hengerer B, Yannaki E, Stamatoyannopoulos J, Benaroya-Milshtein N, Cardona F, Hedderly T, Heyman I, Huyser C, Mir P, Morer A, Mueller N, Munchau A, Plessen K, Porcelli C, Roessner V, Walitza S, Schrag A, Martino D, Group T, TSAICG T, Barr C, Batterson J, Berlin C, Budman C, Coppola G, Cox N, Darrow S, Dion Y, Freimer N, Grados M, Greenberg E, Hirschtritt M, Huang A, Illmann C, King R, Kurlan R, Leckman J, Lyon G, Malaty I, McMahon W, Neale B, Okun M, Osiecki L, Robertson M, Rouleau G, Sandor P, Singer H, Smit J, Sul J, Initiative T, Androutsos C, Basha E, Farkas L, Fichna J, Janik P, Kapisyzi M, Karagiannidis I, Koumoula A, Nagy P, Puchala J, Szejko N, Szymanska U, Tsironi V, Group T, Apter A, Ball J, Bodmer B, Bognar E, Buse J, Vela M, Fremer C, Garcia-Delgar B, Gulisano M, Hagen A, Hagstrøm J, Madruga-Garrido M, Pellico A, Ruhrman D, Schnell J, Silvestri P, Skov L, Steinberg T, Gloor F, Turner V, Weidinger E, Network T, Alexander J, Aranyi T, Buisman W, Buitelaar J, Driessen N, Drineas P, Fan S, Forde N, Gerasch S, van den Heuvel O, Jespersgaard C, Kanaan A, Möller H, Nawaz M, Nespoli E, Pagliaroli L, Poelmans G, Pouwels P, Rizzo F, Veltman D, van der Werf Y, Widomska J, Zilhäo N, Group T, Brown L, Cheon K, Coffey B, Fernandez T, Gilbert D, Hong H, Ibanez-Gomez L, Kim E, Kim Y, Kim Y, Koh Y, Kook S, Kuperman S, Leventhal B, Maras A, Murphy T, Shin E, Song D, Song J, State M, Visscher F, Wang S, Zinner S, Tischfield J, Heiman G, Willsey A, Dietrich A, Davis L, Crowley J, Mathews C, Scharf J, Georgitsi M, Hoekstra P, Paschou P. Genome-Wide Association Study Points to Novel Locus for Gilles de la Tourette Syndrome. Biological Psychiatry 2023, 96: 114-124. PMID: 36738982, PMCID: PMC10783199, DOI: 10.1016/j.biopsych.2023.01.023.Peer-Reviewed Original ResearchExpression quantitative trait lociGenome-wide significant lociWide association study dataComplex genetic architectureQuantitative trait lociAssociation study dataGenetic architectureTrait lociChromosome 5q15Significant lociSignificant enrichmentLociNovel insightsNeurodevelopmental disordersChildhood-onset neurodevelopmental disorderHistonesRNAsGenesPolygenic riskFuture studiesEnrichmentComposition, Treatment, and Outcomes by Radiologically Defined Thrombus Characteristics in Acute Ischemic Stroke
Das S, Goldstein E, de Havenon A, Abbasi M, Nguyen T, de Sousa D, Yaghi S. Composition, Treatment, and Outcomes by Radiologically Defined Thrombus Characteristics in Acute Ischemic Stroke. Stroke 2023, 54: 1685-1694. PMID: 36661035, DOI: 10.1161/strokeaha.122.038563.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeIschemic strokeAdvanced imaging modalitiesStroke treatmentOcclusive thrombusThrombus characteristicsTreatment modalitiesArterial thrombiNeurovascular imagingClot compositionPrevention strategiesTherapy modalitiesThrombusImaging modalitiesPatientsStrokeModalitiesFuture studiesFurther testingTreatmentReview articleClassification systemPathomechanismEpidemiologyImportant cluesBirth Cohort‒Specific Smoking Patterns by Family Income in the U.S.
Jeon J, Cao P, Fleischer N, Levy D, Holford T, Meza R, Tam J. Birth Cohort‒Specific Smoking Patterns by Family Income in the U.S. American Journal Of Preventive Medicine 2023, 64: s32-s41. PMID: 36653231, PMCID: PMC11186479, DOI: 10.1016/j.amepre.2022.07.019.Peer-Reviewed Original ResearchConceptsFederal poverty levelBirth cohortSmoking patternsSmoking prevalenceFamily incomeRecent cohortsRecent birth cohortsHigh-income groupsCessation probabilitiesLower cessationPoverty levelCohortMore recent cohortsSmoking disparitiesPrevalenceIncome groupsIntervention strategiesCohort modelOlder cohortGreater declineLevel groupLow-income individualsCessationCohort differencesFuture studiesExploratory Descriptive Analysis of Smart Speaker Utilization in the Emergency Department During the COVID-19 Pandemic
Franco J, Solad Y, Venkatesh A, Van Tonder R, Solod A, Stachowiak T, Hsiao A, Sangal R. Exploratory Descriptive Analysis of Smart Speaker Utilization in the Emergency Department During the COVID-19 Pandemic. Journal Of Emergency Medicine 2023, 64: 506-512. PMID: 36990854, PMCID: PMC9837211, DOI: 10.1016/j.jemermed.2023.01.004.Peer-Reviewed Original ResearchConceptsEmergency departmentRetrospective observational studyNight shift hoursCOVID-19 pandemicHuman Services OfficePatient satisfactionTelehealth deliveryObservational studyCare conversationsPatient communicationHospital roomHealth Insurance PortabilityExploratory descriptive analysisStaff wellbeingFuture studiesInsurance PortabilityDepartmentDescriptive analysisAccountability ActPandemicPatientsHospitalClinicians
2022
The neurobiology of apathy in depression and neurocognitive impairment in older adults: a review of epidemiological, clinical, neuropsychological and biological research
Steffens D, Fahed M, Manning K, Wang L. The neurobiology of apathy in depression and neurocognitive impairment in older adults: a review of epidemiological, clinical, neuropsychological and biological research. Translational Psychiatry 2022, 12: 525. PMID: 36572691, PMCID: PMC9792580, DOI: 10.1038/s41398-022-02292-3.Peer-Reviewed Original ResearchConceptsPrefrontal cortex circuitCortex circuitPeripheral biomarkersPresence of apathyNeurobiology of apathyPoor health outcomesDefinitive treatmentFuture studiesApathy symptomsClinical managementNeuropsychiatric comorbiditiesFunctional declineCommon conditionNeurocognitive impairmentCognitive disordersNeuropsychological featuresHealth outcomesCognitive impairmentBrain circuitryNeuropsychiatric disordersPrefrontal cortexOlder adultsClinical realityBiomarker researchImpairmentPsychedelics and Neural Plasticity: Therapeutic Implications
Grieco S, Castrén E, Knudsen G, Kwan A, Olson D, Zuo Y, Holmes T, Xu X. Psychedelics and Neural Plasticity: Therapeutic Implications. Journal Of Neuroscience 2022, 42: 8439-8449. PMID: 36351821, PMCID: PMC9665925, DOI: 10.1523/jneurosci.1121-22.2022.Peer-Reviewed Original ResearchConceptsTherapeutic effectNeural plasticityUnmet clinical needFunctional neural plasticityBrain-wide circuitsPsychedelic drugsClinical trialsBasic neuroscience questionsReceptor binding sitesTherapeutic implicationsBrain disordersClinical researchPsychedelic effectsBrain functionClinical needEffects of psychedelicsDrugsNeural mechanismsFuture studiesPsychedelicsGene expressionNeuroscience questionsClinicTrialsIncidence of circumcision among insured adults in the United States
Nabavizadeh B, Li KD, Hakam N, Shaw NM, Leapman MS, Breyer BN. Incidence of circumcision among insured adults in the United States. PLOS ONE 2022, 17: e0275207. PMID: 36251658, PMCID: PMC9576047, DOI: 10.1371/journal.pone.0275207.Peer-Reviewed Original ResearchConceptsAdult circumcisionIncidence rateAge-standardized incidence ratesIncidence of circumcisionAverage incidence rateYears of ageWide geographic variationInsured adultsCommon indicationIBM MarketScanMean ageDiseases codesInternational ClassificationHigh incidenceAge groupsIncidenceStudy periodCircumcisionRitual circumcisionUnited StatesPhimosisSurgeryBalanoposthitisHigh rateFuture studiesModeling ability to resist alcohol in the human laboratory: A pilot study
Sloan M, Sells J, Vaughan C, Morris J, Ortega N, Sundar S, Soundararajan S, Stangl B, Gowin J, Chawla S, Diazgranados N, McKee S, Waters A, Ramchandani V. Modeling ability to resist alcohol in the human laboratory: A pilot study. Drug And Alcohol Dependence Reports 2022, 5: 100105. PMID: 36844167, PMCID: PMC9948911, DOI: 10.1016/j.dadr.2022.100105.Peer-Reviewed Original ResearchAlcohol self-administration paradigmSelf-administration paradigmCox proportional hazards regressionAlcohol usePilot studyLow-risk consumptionRisk of lapseHalf of patientsProportional hazards regressionSelf-administer alcoholAlcohol use disorderAlcohol intakeHazards regressionPriming doseUse disordersScale scoreHeavy drinkersHuman laboratoryImpaired controlInitial exposureCharacteristics of individualsPreliminary evidenceControl Scale scoresFuture studiesIndividuals
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