Rui Wang
Postdoctoral FellowAbout
Research
Publications
Featured Publications
Gut Microbiota-Derived Butyrate Induces Epigenetic and Metabolic Reprogramming in Myeloid-Derived Suppressor Cells to Alleviate Primary Biliary Cholangitis.
Wang R, Li B, Huang B, Li Y, Liu Q, Lyu Z, Chen R, Qian Q, Liang X, Pu X, Wu Y, Chen Y, Miao Q, Wang Q, Lian M, Xiao X, Leung PSC, Gershwin ME, You Z, Ma X, Tang R. Gut Microbiota-Derived Butyrate Induces Epigenetic and Metabolic Reprogramming in Myeloid-Derived Suppressor Cells to Alleviate Primary Biliary Cholangitis. Gastroenterology 2024, 167: 733-749.e3. PMID: 38810839, DOI: 10.1053/j.gastro.2024.05.014.Peer-Reviewed Original Research
2025
Tryptophan catabolites from microbiota ameliorate immune-mediated hepatitis through activating aryl hydrocarbon receptor of T cells.
Li B, Liang X, Li Y, Wang R, Wei Y, Liu Q, Zhang J, Wang Q, Miao Q, Xiao X, Lian M, Wang Z, Zhou Y, Gershwin ME, You Z, Tang R, Ma X. Tryptophan catabolites from microbiota ameliorate immune-mediated hepatitis through activating aryl hydrocarbon receptor of T cells. Gut Microbes 2025, 17: 2557979. PMID: 40995824, DOI: 10.1080/19490976.2025.2557979.Peer-Reviewed Original ResearchOptimizing the tapering scheme of corticosteroid treatment for acute onset of autoimmune hepatitis.
Wang R, Lin Q, Sheng L, Zhang Y, Wen H, Li Y, Shi M, Xiao X, Yan L, Guo C, Miao Q, Hua J, Huang Z, Li H, Gershwin ME, Wang Q, Ma X, Lian M. Optimizing the tapering scheme of corticosteroid treatment for acute onset of autoimmune hepatitis. J Autoimmun 2025, 152: 103387. PMID: 40015068, DOI: 10.1016/j.jaut.2025.103387.Peer-Reviewed Original ResearchGut microbiome pattern impacts treatment response in primary biliary cholangitis.
Liu Q, Huang B, Zhou Y, Wei Y, Li Y, Li B, Li Y, Zhang J, Qian Q, Chen R, Lyu Z, Wang R, Cao Q, Xu Q, Wang Q, Miao Q, You Z, Lian M, Gershwin ME, Jin Q, Xiao X, Ma X, Tang R. Gut microbiome pattern impacts treatment response in primary biliary cholangitis. Med 2025, 6: 100504. PMID: 39305900, DOI: 10.1016/j.medj.2024.08.003.Peer-Reviewed Original Research
2024
Osteoporosis and Primary Biliary Cholangitis: A Trans-ethnic Mendelian Randomization Analysis.
Wu Y, Qian Q, Liu Q, Wang R, Pu X, Li Y, Zhang H, You Z, Miao Q, Xiao X, Lian M, Wang Q, Nakamura M, Gershwin ME, Li Z, Ma X, Tang R. Osteoporosis and Primary Biliary Cholangitis: A Trans-ethnic Mendelian Randomization Analysis. Clin Rev Allergy Immunol 2024, 66: 138-148. PMID: 38554235, DOI: 10.1007/s12016-024-08986-4.Peer-Reviewed Original ResearchImmunosuppression induces regression of fibrosis in primary biliary cholangitis with moderate-to-severe interface hepatitis.
Wang R, Lin Q, Lu Z, Wen H, Hu F, You J, He Y, Fang Y, Bian Z, Hou Q, Ju Z, Wang Y, Lian M, Xiao X, Sheng L, Guo C, Hua J, Tang R, You Z, Chen X, Gershwin ME, Huang Z, Wang Q, Miao Q, Ma X. Immunosuppression induces regression of fibrosis in primary biliary cholangitis with moderate-to-severe interface hepatitis. J Autoimmun 2024, 143: 103163. PMID: 38301505, DOI: 10.1016/j.jaut.2023.103163.Peer-Reviewed Original ResearchItaconate inhibits CD103 + T RM cells and alleviates hepatobiliary injury in mouse models of primary sclerosing cholangitis.
Li Y, Li B, Xiao X, Qian Q, Wang R, Lyu Z, Chen R, Cui N, Ou Y, Pu X, Miao Q, Wang Q, Lian M, Gershwin ME, Tang R, Ma X, You Z. Itaconate inhibits CD103 + T RM cells and alleviates hepatobiliary injury in mouse models of primary sclerosing cholangitis. Hepatology 2024, 79: 25-38. PMID: 37505225, DOI: 10.1097/HEP.0000000000000549.Peer-Reviewed Original Research
2022
Serum Biomarkers for Autoimmune Hepatitis Type 1: the Case for CD48 and a Review of the Literature.
Hu M, You Z, Li Y, Huang B, Cui N, Wang R, Wei Y, Li B, Liang J, Liu Q, Li Y, Wang H, Qian Q, Zhang J, Chen R, Lyu Z, Chen Y, Xiao X, Lian M, Tang R, Miao Q, Wang Q, Ma X. Serum Biomarkers for Autoimmune Hepatitis Type 1: the Case for CD48 and a Review of the Literature. Clin Rev Allergy Immunol 2022, 63: 342-356. PMID: 35657576, DOI: 10.1007/s12016-022-08935-z.Peer-Reviewed Original ResearchAltered faecal microbiome and metabolome in IgG4-related sclerosing cholangitis and primary sclerosing cholangitis.
Liu Q, Li B, Li Y, Wei Y, Huang B, Liang J, You Z, Li Y, Qian Q, Wang R, Zhang J, Chen R, Lyu Z, Chen Y, Shi M, Xiao X, Wang Q, Miao Q, Fang JY, Gershwin ME, Lian M, Ma X, Tang R. Altered faecal microbiome and metabolome in IgG4-related sclerosing cholangitis and primary sclerosing cholangitis. Gut 2022, 71: 899-909. PMID: 34035120, DOI: 10.1136/gutjnl-2020-323565.Peer-Reviewed Original ResearchSerum Immunoglobulin G Levels Predict Biochemical and Histological Remission of Autoimmune Hepatitis Type 1: A Single-Center Experience and Literature Review.
Li Y, Yan L, Wang R, Wang Q, You Z, Li B, Zhang J, Huang B, Chen Y, Li Y, Lian M, Tang R, Qiu D, Gershwin ME, Xiao X, Miao Q, Ma X. Serum Immunoglobulin G Levels Predict Biochemical and Histological Remission of Autoimmune Hepatitis Type 1: A Single-Center Experience and Literature Review. Clin Rev Allergy Immunol 2022, 62: 292-300. PMID: 33512642, DOI: 10.1007/s12016-021-08833-w.Peer-Reviewed Original Research
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