Valentina Restrepo-Espinosa, MD
Postdoctoral AssociateAbout
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Featured Publications
Burnout in Sickle Cell Disease-Focused Hematology-Oncology Trained Physicians: A National Cross-Sectional Study
Restrepo V, Marshall A, Feder K, Afranie-Sakyi J, Carrithers B, Jones-Wonni B, Mensah C, Zhou B, Mistry R, McGann P, Azar S, De Castro L, Calhoun C, Bozang K, Brown T, Lee A, Van Doren L. Burnout in Sickle Cell Disease-Focused Hematology-Oncology Trained Physicians: A National Cross-Sectional Study. Blood Advances 2026 PMID: 41817318, DOI: 10.1182/bloodadvances.2025018338.Peer-Reviewed Original ResearchThis study investigates burnout in U.S. hematology-oncology physicians specializing in sickle cell disease, showing higher burnout rates linked to systemic factors, reduced recreation, and lower job pride.
2025
Defining the ideal endovascular solution to various thoracoabdominal aortopathies requires a shift in perspective and an open mind
Defining the ideal endovascular solution to various thoracoabdominal aortopathies requires a shift in perspective and an open mind Restrepo-Espinosa, ValentinaKelly, Patrick W.Vallabhajosyula, PrashanthAnswini, Geoffrey A.Lee, Robert E.Nassiri, Naiem et al. Journal of Vascular Surgery, Volume 82, Issue 2, 705 - 706Commentaries, Editorials and LettersPositive aortic remodeling elevates the bar for defining endovascular aortic repair success
Positive aortic remodeling elevates the bar for defining endovascular aortic repair success Restrepo, ValentinaNassiri, Naiem et al. Journal of Vascular Surgery, Volume 82, Issue 2, 709 - 710Commentaries, Editorials and LettersMulticenter Experience With the Unitary Stent Graft System for Endovascular Debranched Aortic Repair of Various Thoracoabdominal Aortopathies
Pupovac S, Restrepo-Espinosa V, Chen J, Zaky M, Answini G, Kelly P, Vallabhajosyula P, Nassiri N. Multicenter Experience With the Unitary Stent Graft System for Endovascular Debranched Aortic Repair of Various Thoracoabdominal Aortopathies. The Annals Of Thoracic Surgery 2025, 120: 442-449. PMID: 40484210, DOI: 10.1016/j.athoracsur.2025.05.026.Peer-Reviewed Original ResearchThoracoabdominal aortic aneurysmsAortic repairOpen surgeryTechnical successAortic aneurysmPatency ratesShort-neck infrarenal aneurysmsTarget vessel patency rateMedian hospital stayThirty-day mortalityClinical follow-upMajor adverse eventsStent Graft SystemMulti-center experienceMulti-center studyMedian followChronic dissectionInfrarenal aneurysmsReintervention rateEndoluminal bypassInfrarenal EVARThirty-dayStent graftHospital stayAdverse eventsPerformance of Xpert MTB/RIF and acid-fast bacilli smear microscopy for the diagnosis of pulmonary tuberculosis using bronchoalveolar lavage samples in negative or sputum-scarce adults in Colombia: a retrospective diagnostic accuracy study.
Sabella-Jiménez V, Sabella-Jiménez VL, Restrepo-Espinosa V, Eljadue-Flórez J, Gallardo-Castro CV, Silvera AA, Otero-Herrera C, Arroyo HAM, Acosta-Reyes J, Barrios JLQ. Performance of Xpert MTB/RIF and acid-fast bacilli smear microscopy for the diagnosis of pulmonary tuberculosis using bronchoalveolar lavage samples in negative or sputum-scarce adults in Colombia: a retrospective diagnostic accuracy study. BMC Infect Dis 2025, 25: 491. PMID: 40205580, DOI: 10.1186/s12879-025-10856-z.Peer-Reviewed Original Research
2024
In-human clinical experience with direct stick embolization of low-flow vascular malformations using a mammalian target of rapamycin inhibitor
Restrepo-Espinosa V, Lee A, Prozora S, Patel P, Nassiri N. In-human clinical experience with direct stick embolization of low-flow vascular malformations using a mammalian target of rapamycin inhibitor. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2024, 13: 101997. PMID: 39515753, PMCID: PMC12014304, DOI: 10.1016/j.jvsv.2024.101997.Peer-Reviewed Original ResearchLow-flow vascular malformationsMTOR inhibitorsClinical successVascular malformationsSide effectsLocalized intravascular coagulopathyOral aphthous ulcersKlippel-Trenaunay syndromeLymphatic malformationsVenous malformationsRe-interventionDelayed complicationsNon-syndromicTechnical successAphthous ulcersIntravascular coagulopathyD-dimerEndovascular treatmentSystemic exposureAdjunctive therapySystemic toxicityFrequent bloodMalformationsSelf-limitingMTOR inhibitionSystemic Estrogen Therapy and Thrombosis: A Call for Individualized Clinical Decision Making in the Acute Care Setting
Restrepo V, Martin K, Van Doren L. Systemic Estrogen Therapy and Thrombosis: A Call for Individualized Clinical Decision Making in the Acute Care Setting. Clinical Therapeutics 2024, 46: 949-952. PMID: 39443265, DOI: 10.1016/j.clinthera.2024.09.026.Peer-Reviewed Original ResearchConceptsAcute care settingSystemic estrogen therapyCare settingsHeavy menstrual bleedingHealth careGender-affirming hormone therapyIntegral to health careVenous thromboembolismReduce health inequalitiesAffirming health careHealth care deliveryMenopausal symptomsPatient-centered approachEstrogen therapyAdherence to anticoagulation therapyCases of heavy menstrual bleedingQuality of lifeIncreased risk of venous thromboembolismRisk of VTE recurrenceIndividual patient needsHealth inequalitiesCare deliveryRisk of venous thromboembolismHormone replacement therapyIndividualized careTrainees’ perspectives on sickle cell education: a qualitative needs assessment
Prince E, Feder K, Calhoun C, Lee A, Carroll C, Restrepo V, Van Doren L. Trainees’ perspectives on sickle cell education: a qualitative needs assessment. BMC Medical Education 2024, 24: 715. PMID: 38956512, PMCID: PMC11220977, DOI: 10.1186/s12909-024-05696-5.Peer-Reviewed Original ResearchConceptsNeeds assessmentPatient care challengesIterative thematic analysisQualitative needs assessmentCost of careComplications of SCDBackgroundSickle cell diseaseCare challengesHealthcare biasesSpecific educationThematic analysisMedical traineesFocus groupsClinical careTrainees' attitudesQualitative interviewsLack of national standardsLongitudinal exposureClinical teachingUnited StatesExpert cliniciansSubspecialty trainingTraineesCareHealthcare
2023
Comprehensive Characterization of Coagulation Parameters in Venous Malformations
Valentina Restrepo, Alexander B Pine, Ayesha Butt, Eric Y Chang, Noffar Bar, Audrey Baluha, Andrea Brooks, Giavanna Chirico, Jeffrey Curran, Anne Dumont, Pauline Obura-Wilkes, Henry M Rinder, Christopher Tormey, Naiem Nassiri, Alfred I Lee, Stephanie Prozora; Comprehensive Characterization of Coagulation Parameters in Venous Malformations. Blood 2023; 142 (Supplement 1): 27. doi: https://doi.org/10.1182/blood-2023-190609Peer-Reviewed Original ResearchProteomic Profiling of Different Antiphospholipid Antibody-Positive Phenotypes: Results from Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION) Registry
Alexander B Pine, Ayesha Butt, Rolando Garcia-Milian, Sean X Gu, Valentina Restrepo, Yu Pei Chock, John Hwa, Christopher Tormey, Henry M Rinder, George Goshua, H Michael Belmont, Maria Bertolaccini, David Ware Branch, Doruk Erhan, Nina Kello, Jason Knight, Michelle Petri, Rohan Willis, Alfred I Lee, Anish V Sharda; Proteomic Profiling of Different Antiphospholipid Antibody-Positive Phenotypes: Results from Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION) Registry. Blood 2023; 142 (Supplement 1): 2575. doi: https://doi.org/10.1182/blood-2023-185232Peer-Reviewed Original Research
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