Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsSuhas Ganesh
Assistant Professor (Adjunct) of PsychiatryAbout
Research
Publications
2024
A Novel Homozygous Variant in CPLANE1 Gene in a Patient with Developmental Deficits
Shankarappa B, Prasad V, Kumar S, Rao R, Royal A, Swamy M, Prasad P, Murthy A, Ganesh S, Viswanath B, Jain S, Purushottam M, Thyloth M. A Novel Homozygous Variant in CPLANE1 Gene in a Patient with Developmental Deficits. Molecular Syndromology 2024, 16: 87-92. PMID: 39911166, PMCID: PMC11793906, DOI: 10.1159/000541167.Peer-Reviewed Original ResearchOral-facial-digital syndromeOrofacial anomaliesRare syndromeJoubert syndromeOral-facial-digital syndrome type 1Features of Joubert syndromeClinical exome sequencingWild-type alleleRural community clinicsStructural chromosomal abnormalitiesSubstitution of glycineMild developmental delayX-linked dominant inheritanceAutosomal recessive inheritanceMutation databaseChromosomal microarrayDevelopmental deficitsExome sequencingGenetic analysisOrofacial featuresRare subtypeSanger sequencingChromosomal abnormalitiesExon 5Gene c.DECIPHERING THE UNDERLYING BIOLOGY OF PSYCHIATRIC DISORDERS THROUGH LONGITUDINAL FAMILY COHORT BASED STUDIES IN INDIA
Viswanath B, Sud R, Ganesh S, Mahadevan J, Holla B, Paul P, Purushottam M, Jain S, Consortium A. DECIPHERING THE UNDERLYING BIOLOGY OF PSYCHIATRIC DISORDERS THROUGH LONGITUDINAL FAMILY COHORT BASED STUDIES IN INDIA. European Neuropsychopharmacology 2024, 87: 43-44. DOI: 10.1016/j.euroneuro.2024.08.108.Peer-Reviewed Original ResearchAdverse childhood eventsWhole-exome sequencingFirst-degree relativesChildhood eventsStudies of psychiatric disordersFamily history densityObsessive compulsive disorderGenetic studies of psychiatric disordersSubstance use disordersPeripheral blood mononuclear cellsSevere mental illnessLongitudinal family cohortGenetic studiesAge-of-onsetTransdiagnostic endophenotypesBrain imaging abnormalitiesCompulsive disorderBipolar disorderPsychiatric diagnosisPsychiatric disordersMultiple affected membersCognitive performanceRare damaging variantsMental illnessCognitive AssessmentW32. A GENOME-WIDE ASSOCIATION STUDY OF BIPOLAR DISORDER FROM INDIA
Mahadevan J, Holla B, Ganesh S, Shankarappa B, Paul P, Sud R, Jain S, Purushottam M, Viswanath B. W32. A GENOME-WIDE ASSOCIATION STUDY OF BIPOLAR DISORDER FROM INDIA. European Neuropsychopharmacology 2024, 87: 118. DOI: 10.1016/j.euroneuro.2024.08.241.Peer-Reviewed Original ResearchGenome-wide association studiesGenomic risk lociRisk lociAssociation studiesGenome-wide association study of BDGenome wide association studiesAncestry principal componentsSevere mental illnessWhole-genome sequencingTissue expression analysisBiology of BdPatients of European ancestryBipolar disorderHRC panelGenome sequenceMental illnessAncestry samplesGenomic methodsEpisodes of depressionAllele dosageGenetic studiesEuropean ancestryICD-10Outpatient clinicTrained psychiatristsF67. CHARACTERIZING THE IMPACT OF AUTOZYGOSITY AND RUNS OF HOMOZYGOSITY ON PSYCHIATRIC DISEASE RISK IN INDIAN POPULATION
Kandasamy K, Ganesh S, Sachdeva P, Mahadevan J, Holla B, Benegal V, Purushottam M, Jain S, Viswanath B. F67. CHARACTERIZING THE IMPACT OF AUTOZYGOSITY AND RUNS OF HOMOZYGOSITY ON PSYCHIATRIC DISEASE RISK IN INDIAN POPULATION. European Neuropsychopharmacology 2024, 87: 242. DOI: 10.1016/j.euroneuro.2024.08.478.Peer-Reviewed Original ResearchGenetic architecture of psychiatric disordersIllumina Global Screening ArrayGlobal Screening ArrayContinental populationsGenetic architectureInbreeding coefficientRecessive locusAutozygosityFROHObsessive compulsive disorderScreening ArrayPLINK v.GenomeInbreedingBipolar disorderDisease-riskPsychiatric diagnosisPsychiatric disordersDisease riskEndogamyIlluminaCase-control differencesLociPLINKROHW94. ALLELE FREQUENCIES AT CRUCIAL LOCI MIGHT UNDERLIE DISPARATE CONSEQUENCES OF ALCOHOL ABUSE ACROSS WORLD POPULATIONS
Shankarappa B, Ganesh S, Purushottam M, Jain S. W94. ALLELE FREQUENCIES AT CRUCIAL LOCI MIGHT UNDERLIE DISPARATE CONSEQUENCES OF ALCOHOL ABUSE ACROSS WORLD POPULATIONS. European Neuropsychopharmacology 2024, 87: 151. DOI: 10.1016/j.euroneuro.2024.08.303.Peer-Reviewed Original ResearchDistribution of allele frequenciesAllele frequenciesAlcohol use disorderAlcohol-related comorbiditiesAlcohol abuseUse disorderHeritability of alcohol use disordersRisk of diseaseIll healthSequence alignmentSIFT scoreAlcohol consumptionAlcohol-related complicationsHealth consequencesAlcohol useAssociated with alcoholDisease burdenConsequences of alcohol abuseHealth complicationsContext of alcohol abuseRisk factorsHealthGenetic predispositionMetabolize alcoholCultural practicesF35. INVESTIGATING GENETIC RISK FOR PSYCHOSIS IN BIPOLAR DISORDER IN INDIA USING POLYGENIC SCORES
Jeevan Y, Mahadevan J, Viswanath B, Jain S, Ganesh S, Holla B, Purushottam M, Shankarappa B, consortium A, India S. F35. INVESTIGATING GENETIC RISK FOR PSYCHOSIS IN BIPOLAR DISORDER IN INDIA USING POLYGENIC SCORES. European Neuropsychopharmacology 2024, 87: 224. DOI: 10.1016/j.euroneuro.2024.08.446.Peer-Reviewed Original ResearchPsychotic symptomsBipolar disorderPolygenic scoresGenetic susceptibility to bipolar disorderAbsence of psychotic symptomsHistory of psychotic symptomsPresence of psychotic symptomsClinical heterogeneity of BDCourse of maniaSchizophrenia polygenic scoreRisk of psychosisChronic mental disordersHeterogeneity of BDSusceptibility to bipolar disorderOdds of psychosisRisk of BDEpisodic courseBD-PRSMental disordersPsychosisIndependent dimensionsBD-1Investigate genetic riskGenetic riskManiaW48. PROFILING THE RARE VARIANT GENETIC RISK FOR DEMENTIA WITH WHOLE EXOME SEQUENCING: A STUDY FROM INDIA
Patra C, Ganesh S, Mahadevan J, Gujarati K, Awasthy D, George S, Ganapathy A, Phalke S, Bettadapura R, Viswanath B, Varghese M, Jain S, Prasad P, Purushottam M. W48. PROFILING THE RARE VARIANT GENETIC RISK FOR DEMENTIA WITH WHOLE EXOME SEQUENCING: A STUDY FROM INDIA. European Neuropsychopharmacology 2024, 87: 126. DOI: 10.1016/j.euroneuro.2024.08.257.Peer-Reviewed Original ResearchVariants of Uncertain SignificanceClinical exome sequencingICD-10 diagnosis of dementiaExome sequencingFronto-temporal dementiaFamily historyMAPT geneExonic variantsAlzheimer's diseaseRare genetic risk variantsDiagnosis of dementiaRisk variantsAbnormal tau protein aggregationDiverse populationsPathogenic variantsICD-10 diagnosisRare variantsGenetic risk variantsExome data analysisAPOE e4 alleleTau protein aggregationRare exonic variantsNational Institute of Mental Health and NeurosciencesWhole-exome sequencingGeriatric clinicBehavioral, Cognitive and Electrophysiological Presentation and Short-Term Course of Cannabis Related First Episode Psychosis
D'Souza D, Raj J, Ganesh S, Goyal N, Vidya K, Tikka S, Shreekantiah U, Murthy P, Sinha V, Ram D, Cortes J. Behavioral, Cognitive and Electrophysiological Presentation and Short-Term Course of Cannabis Related First Episode Psychosis. Biological Psychiatry 2024, 95: s29. DOI: 10.1016/j.biopsych.2024.02.076.Peer-Reviewed Original ResearchAltered neuroepithelial morphogenesis and migration defects in iPSC-derived cerebral organoids and 2D neural stem cells in familial bipolar disorder
Phalnikar K, Srividya M, Mythri S, Vasavi N, Ganguly A, Kumar A, S P, Kalia K, Mishra S, Dhanya S, Paul P, Holla B, Ganesh S, Reddy P, Sud R, Viswanath B, Muralidharan B. Altered neuroepithelial morphogenesis and migration defects in iPSC-derived cerebral organoids and 2D neural stem cells in familial bipolar disorder. Oxford Open Neuroscience 2024, 3: kvae007. PMID: 38638145, PMCID: PMC11024480, DOI: 10.1093/oons/kvae007.Peer-Reviewed Original ResearchPatient organoidsNeural stem cellsBipolar disorderStem cellsTranscriptome analysis of controlPatient-derived organoidsFamilial bipolar disorderMigration defectsNeural stem cell culturesDysregulation of genesFamilial BDBD patientsCausative genetic variantsSox2-positiveNeurodevelopmental aberrationsNeurodevelopmental anomaliesIPSC-derived cerebral organoidsProgenitor proliferationStem cell culturesAbnormal positionPatientsNeuronal migrationCortical organoidsMolecular deficitsCycling progenitorsHybrid Tele-cognitive Behavioural Therapy (Ht-CBT) for Obsessive-compulsive Disorder: An Innovation Integrating In-person and Online Psychotherapy
Ganesh S, Sharma L, Das B. Hybrid Tele-cognitive Behavioural Therapy (Ht-CBT) for Obsessive-compulsive Disorder: An Innovation Integrating In-person and Online Psychotherapy. Indian Journal Of Psychological Medicine 2024, 46: 276-278. PMID: 38699761, PMCID: PMC11062316, DOI: 10.1177/02537176231219768.Peer-Reviewed Original Research