Shivani Srivastava, PhD
Postdoctoral AssociateDownloadHi-Res Photo
Cards
Education
PhD
(Biochemistry), Institute of Medical Sciences, BHU, India
(Biochemistry), Institute of Medical Sciences, BHU, India
MSc
(Biochemistry), Institute of Science, BHU, India
(Biochemistry), Institute of Science, BHU, India
Training
Postdoctoral Scholar
David Geffen School of Medicine, UCLA, USA
David Geffen School of Medicine, UCLA, USA
Postdoctoral Scholar
Wexner Medical Center, OSU, USA
Wexner Medical Center, OSU, USA
Braddock Lab
Education
PhD
(Biochemistry), Institute of Medical Sciences, BHU, India
(Biochemistry), Institute of Medical Sciences, BHU, India
MSc
(Biochemistry), Institute of Science, BHU, India
(Biochemistry), Institute of Science, BHU, India
Training
Postdoctoral Scholar
David Geffen School of Medicine, UCLA, USA
David Geffen School of Medicine, UCLA, USA
Postdoctoral Scholar
Wexner Medical Center, OSU, USA
Wexner Medical Center, OSU, USA
Braddock Lab
Education
PhD
(Biochemistry), Institute of Medical Sciences, BHU, India
(Biochemistry), Institute of Medical Sciences, BHU, India
MSc
(Biochemistry), Institute of Science, BHU, India
(Biochemistry), Institute of Science, BHU, India
Training
Postdoctoral Scholar
David Geffen School of Medicine, UCLA, USA
David Geffen School of Medicine, UCLA, USA
Postdoctoral Scholar
Wexner Medical Center, OSU, USA
Wexner Medical Center, OSU, USA
Braddock Lab
About
Titles
Postdoctoral Associate
Appointments
Education & Training
- Postdoctoral Scholar
- David Geffen School of Medicine, UCLA, USA
- Postdoctoral Scholar
- Wexner Medical Center, OSU, USA
- PhD
- (Biochemistry), Institute of Medical Sciences, BHU, India
- Guest Faculty
- B.Voc. in Medical Lab Technology, BHU, India
- Senior Research Fellow
- IIVR, Indian Council of Agricultural Research, India
- MSc
- (Biochemistry), Institute of Science, BHU, India
- BSc (Hon)
- (Botany, Zoology, Chemistry), BHU, India
Research
Overview
Medical Research Interests
Aging; Bone Diseases; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Obesity
ORCID
0000-0001-8042-4476- View Lab Website
Braddock Lab
Research at a Glance
Yale Co-Authors
Frequent collaborators of Shivani Srivastava's published research.
Publications Timeline
A big-picture view of Shivani Srivastava's research output by year.
Demetrios Braddock, MD, PhD
Fotios Koumpouras, MD
Joao Pereira, PhD
Paul Stabach
24Publications
1Citations
Publications
Featured Publications
Catalysis-Independent ENPP1 Protein Signaling Regulates Mammalian Bone Mass
Zimmerman K*, Liu X*, von Kroge S*, Stabach P, Lester ER, Chu EY, Srivastava S, Somerman MJ, Tommasini SM, Busse B, Schinke T, Carpenter TO, Oheim R, Braddock DT. Catalysis‐Independent ENPP1 Protein Signaling Regulates Mammalian Bone Mass. Journal Of Bone And Mineral Research 2020, 37: 1733-1749. PMID: 35773783, PMCID: PMC9709593, DOI: 10.1002/jbmr.4640.Peer-Reviewed Original ResearchA dual-acting DNASE1/DNASE1L3 biologic prevents autoimmunity and death in genetic and induced lupus models
Stabach P, Sims D, Gomez-Bañuelos E, Zehentmeier S, Dammen-Brower K, Bernhisel A, Kujawski S, Lopez S, Petri M, Goldman D, Lester E, Le Q, Ishaq T, Kim H, Srivastava S, Kumar D, Pereira J, Yarema K, Koumpouras F, Andrade F, Braddock D. A dual-acting DNASE1/DNASE1L3 biologic prevents autoimmunity and death in genetic and induced lupus models. JCI Insight 2024, 9: e177003. PMID: 38888971, PMCID: PMC11383374, DOI: 10.1172/jci.insight.177003.Peer-Reviewed Original ResearchCitationsAltmetricConceptsSystemic lupus erythematosusDNASE1L3 deficiencySporadic systemic lupus erythematosusAssociated with systemic lupus erythematosusChromatin degradationDNA accumulationDevelopment of lupusPristane-induced lupusSelf-DNACell free DNAHuman isoformsSystemic lupus erythematosus plasmasDouble knockout miceDNASE1L3Pathogenic effectsFree DNALupus modelEnzymeInducible lupus modelAdult patientsLupus erythematosusKnockout micePediatric populationAutoimmune diseasesDNAExpression kinetics reveal the self-adaptive role of β cells during the progression of diabetes.
Srivastava S, Pandey H, Tripathi YB. Expression kinetics reveal the self-adaptive role of β cells during the progression of diabetes. Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie 2018, 106: 472-482. PMID: 29990835, DOI: 10.1016/j.biopha.2018.06.168.Peer-Reviewed Original ResearchIncretin hormones receptor signaling plays the key role in antidiabetic potential of PTY-2 against STZ-induced pancreatitis.
Srivastava S, Shree P, Pandey H, Tripathi YB. Incretin hormones receptor signaling plays the key role in antidiabetic potential of PTY-2 against STZ-induced pancreatitis. Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie 2018, 97: 330-338. PMID: 29091882, DOI: 10.1016/j.biopha.2017.10.071.Peer-Reviewed Original ResearchGLP 1 Regulated Intestinal Cell's Insulin Expression and Selfadaptation before the Onset of Type 2 Diabetes.
Srivastava S, Pandey H, Singh SK, Tripathi YB. GLP 1 Regulated Intestinal Cell's Insulin Expression and Selfadaptation before the Onset of Type 2 Diabetes. Advanced Pharmaceutical Bulletin 2019, 9: 325-330. PMID: 31380261, PMCID: PMC6664108, DOI: 10.15171/apb.2019.039.Peer-Reviewed Original ResearchActive phytochemicals of Pueraria tuberosa for DPP-IV inhibition: in silico and experimental approach.
Srivastava S, Shree P, Tripathi YB. Active phytochemicals of Pueraria tuberosa for DPP-IV inhibition: in silico and experimental approach. Journal Of Diabetes And Metabolic Disorders 2017, 16: 46. PMID: 29201861, PMCID: PMC5697100, DOI: 10.1186/s40200-017-0328-0.Peer-Reviewed Original ResearchAnti-oxidant, anti-apoptotic, anti-hypoxic and anti-inflammatory conditions induced by PTY-2 against STZ-induced stress in islets.
Srivastava S, Pandey H, Singh SK, Tripathi YB. Anti-oxidant, anti-apoptotic, anti-hypoxic and anti-inflammatory conditions induced by PTY-2 against STZ-induced stress in islets. Bioscience Trends 2019, 13: 382-393. PMID: 31597821, DOI: 10.5582/bst.2019.01181.Peer-Reviewed Original ResearchPueraria tuberosa as Dipeptidyl-Peptidase-IV Inhibitor Prevents Streptozotocin-Induced Intestinal Stress.
Srivastava S, Pandey H, Singh SK, Tripathi YB. Pueraria tuberosa as dipeptidyl-peptidase-IV inhibitor prevents streptozotocin-induced intestinal stress. Open Access Macedonian Journal of Medical Sciences. 2021;9(A):28-34.Peer-Reviewed Original ResearchRevolutionizing Immunotherapy: Unveiling New Horizons, Confronting Challenges, and Navigating Therapeutic Frontiers in CAR-T Cell-Based Gene Therapies
Srivastava S*, Tyagi A*, Pawar VA*, Khan NH*, Arora K, Verma C, Kumar V. Revolutionizing Immunotherapy: Unveiling New Horizons, Confronting Challenges, and Navigating Therapeutic Frontiers in CAR-T Cell-Based Gene Therapies. Immunotargets Ther 2024, 13: 413-433. PMID: 39219644, DOI: 10.2147/ITT.S474659.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsImmune Modulatory Effects of Ketogenic Diet in Different Disease Conditions
Srivastava, S*, Pawar, V.A*, Tyagi, A*, Sharma, K.P*, Kumar, V.; Shukla, S.K. Immune Modulatory Effects of Ketogenic Diet in Different Disease Conditions. Immuno 2023, 3, 1-15. https://doi.org/10.3390/immuno3010001Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
Academic Achievements & Community Involvement
activity BMC Complementary Medicine and Therapies, Diabetology & Metabolic Syndrome, Frontiers in Endocrinology, Cellular Physiology and Biochemistry, Frontiers in Immunology, Frontiers in Pharmacology, International Journal of Data Mining and Bioinformatics, Journal of Diabetes Research, Journal of Obesity, Molecular Biology Reports, Oncology Research, Frontiers in Cardiovascular Medicine, PLOS ONE, Scientific report, Frontiers in Molecular Biosciences (TOTAL=51 reviews).
Journal ServiceReviewerDetails2022 - Presentactivity Frontiers in Aging (TOPIC: Premature Aging, its Consequences, and Targeted Therapy)
Journal ServiceGuest EditorDetails2024 - Presenthonor Young Investigator Award
International AwardThe American Society for Bone and Mineral Research (ASBMR)Details09/28/2024Canadahonor Registration Award Recipient
International AwardGordon Conference on the Physiology, Biology and Pathology of PhosphateDetails02/10/2023United Stateshonor Best Research Paper
National AwardDr. P.D. Sethi Memorial Annual National AwardsDetails04/30/2019India
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