Ramakrishnan Kannan, PhD
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Neuroscience
Primary
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About
Titles
Associate Research Scientist
Appointments
Neuroscience
Associate Research ScientistPrimary
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Education & Training
- Postdoctoral Fellow
- National Institutes of Health (2015)
- PhD
- Tamil Nadu Agricultural University, Biotechnology (2004)
Research
Research at a Glance
Publications Timeline
A big-picture view of Ramakrishnan Kannan's research output by year.
19Publications
25Citations
Publications
2020
Dynamic morphogenesis of a pioneer axon in Drosophila and its regulation by Abl tyrosine kinase.
Clarke A, McQueen PG, Fang HY, Kannan R, Wang V, McCreedy E, Buckley T, Johannessen E, Wincovitch S, Giniger E. Dynamic morphogenesis of a pioneer axon in Drosophila and its regulation by Abl tyrosine kinase. Molecular Biology Of The Cell 2020, 31: 452-465. PMID: 31967935, PMCID: PMC7185889, DOI: 10.1091/mbc.E19-10-0563.Peer-Reviewed Original ResearchAbl signaling directs growth of a pioneer axon in Drosophila by shaping the intrinsic fluctuations of actin.
Clarke A, McQueen PG, Fang HY, Kannan R, Wang V, McCreedy E, Wincovitch S, Giniger E. Abl signaling directs growth of a pioneer axon in Drosophila by shaping the intrinsic fluctuations of actin. Molecular Biology Of The Cell 2020, 31: 466-477. PMID: 31967946, PMCID: PMC7185895, DOI: 10.1091/mbc.E19-10-0564.Peer-Reviewed Original Research
2019
Identification and functional characterization of two novel mutations in KCNJ10 and PI4KB in SeSAME syndrome without electrolyte imbalance.
Nadella RK, Chellappa A, Subramaniam AG, More RP, Shetty S, Prakash S, Ratna N, Vandana VP, Purushottam M, Saini J, Viswanath B, Bindu PS, Nagappa M, Mehta B, Jain S, Kannan R. Identification and functional characterization of two novel mutations in KCNJ10 and PI4KB in SeSAME syndrome without electrolyte imbalance. Human Genomics 2019, 13: 53. PMID: 31640787, PMCID: PMC6805350, DOI: 10.1186/s40246-019-0236-0.Peer-Reviewed Original ResearchChronic Exposure to Chewing Tobacco Induces Metabolic Reprogramming and Cancer Stem Cell-Like Properties in Esophageal Epithelial Cells
Datta KK, Patil S, Patel K, Babu N, Raja R, Nanjappa V, Mangalaparthi KK, Dhaka B, Rajagopalan P, Deolankar SC, Kannan R, Kumar P, Prasad TSK, Mathur PP, Kumari A, Manoharan M, Coral K, Murugan S, Sidransky D, Gupta R, Gupta R, Khanna-Gupta A, Chatterjee A, Gowda H. Chronic Exposure to Chewing Tobacco Induces Metabolic Reprogramming and Cancer Stem Cell-Like Properties in Esophageal Epithelial Cells. Cells 2019, 8: 949. PMID: 31438645, PMCID: PMC6770059, DOI: 10.3390/cells8090949.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsEsophageal epithelial cellsQuantitative proteomic analysisQuantitative proteomic profilingEpithelial cellsCancer stem cell-like phenotypeElectron transport chainEsophageal squamous cell carcinomaStem cell-like phenotypeTricarboxylic acid cycleMolecular alterationsMitochondrial proteinsTobacco exposurePhosphorylation phenotypeProteomic analysisCell-like phenotypeStem cell-like propertiesMetabolic reprogrammingProteomic profilingCancer stem cell-like propertiesOXPHOS phenotypeStem cell markersChronic exposureTransport chainCell-like propertiesMolecular markersDoes retinoic acid reverse cell cycle dysregulation in Alzheimer's disease lymphocytes?
Ashok A, Naaz S, Kota LN, Sen S, Purushottam M, Faruq M, Kumari R, Yadav V, Kannan R, Jain S, Panicker MM, Viswanath B. Does retinoic acid reverse cell cycle dysregulation in Alzheimer's disease lymphocytes? Asian Journal Of Psychiatry 2019, 39: 174-177. PMID: 30139662, DOI: 10.1016/j.ajp.2018.08.010.Peer-Reviewed Original ResearchDerivation of iPSC lines from two patients with familial Alzheimer's disease from India.
Najar AH, Sneha KM, Ashok A, Babu S, Subramaniam AG, Kannan R, Viswanath B, Purushottam M, Varghese M, Parvez S, Panicker MM, Mukherjee O, Jain S. Derivation of iPSC lines from two patients with familial Alzheimer's disease from India. Stem Cell Research 2019, 34: 101370. PMID: 30605839, DOI: 10.1016/j.scr.2018.101370.Peer-Reviewed Original Research
2018
Discovery biology of neuropsychiatric syndromes (DBNS): a center for integrating clinical medicine and basic science.
Viswanath B, Rao NP, Narayanaswamy JC, Sivakumar PT, Kandasamy A, Kesavan M, Mehta UM, Venkatasubramanian G, John JP, Mukherjee O, Purushottam M, Kannan R, Mehta B, Kandavel T, Binukumar B, Saini J, Jayarajan D, Shyamsundar A, Moirangthem S, Vijay Kumar KG, Thirthalli J, Chandra PS, Gangadhar BN, Murthy P, Panicker MM, Bhalla US, Chattarji S, Benegal V, Varghese M, Reddy JYC, Raghu P, Rao M, Jain S. Discovery biology of neuropsychiatric syndromes (DBNS): a center for integrating clinical medicine and basic science. BMC Psychiatry 2018, 18: 106. PMID: 29669557, PMCID: PMC5907468, DOI: 10.1186/s12888-018-1674-2.Peer-Reviewed Original ResearchTyrosine phosphorylation and proteolytic cleavage of Notch are required for non-canonical Notch/Abl signaling in Drosophila axon guidance.
Kannan R, Cox E, Wang L, Kuzina I, Gu Q, Giniger E. Tyrosine phosphorylation and proteolytic cleavage of Notch are required for non-canonical Notch/Abl signaling in Drosophila axon guidance. Development (Cambridge, England) 2018, 145 PMID: 29343637, PMCID: PMC5825841, DOI: 10.1242/dev.151548.Peer-Reviewed Original Research
2017
New perspectives on the roles of Abl tyrosine kinase in axon patterning.
Kannan R, Giniger E. New perspectives on the roles of Abl tyrosine kinase in axon patterning. Fly 2017, 11: 260-270. PMID: 28481649, PMCID: PMC5721943, DOI: 10.1080/19336934.2017.1327106.Peer-Reviewed Original ResearchThe Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila.
Kannan R, Song JK, Karpova T, Clarke A, Shivalkar M, Wang B, Kotlyanskaya L, Kuzina I, Gu Q, Giniger E. The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila. Development (Cambridge, England) 2017, 144: 487-498. PMID: 28087633, PMCID: PMC5341800, DOI: 10.1242/dev.143776.Peer-Reviewed Original Research