Voluntary Faculty
Voluntary faculty are typically clinicians or others who are employed outside of the School but make significant contributions to department programs at the medical center or at affiliate institutions.
Voluntary rank detailsNgoc Nguyen, PhD, DABR
Assistant Clinical ProfessorAbout
Research
Publications
2024
Interventional antibiotic treatment replacing antibiotic prophylaxis during allogeneic hematopoietic stem cell transplantation is safe and leads to a reduction of antibiotic administration
Toenges R, Lang F, Ghaffar R, Lindner S, Schlipfenbacher V, Riemann J, Ajib S, Kouidri K, Cremer A, Weber B, Nguyen N, Knoch A, Vehreschild J, Serve H, Bug G. Interventional antibiotic treatment replacing antibiotic prophylaxis during allogeneic hematopoietic stem cell transplantation is safe and leads to a reduction of antibiotic administration. Annals Of Hematology 2024, 103: 4687-4699. PMID: 39237814, DOI: 10.1007/s00277-024-05986-4.Peer-Reviewed Original ResearchGraft-versus-host diseaseSystemic antibiotic prophylaxisNon-relapse mortalityChronic graft-versus-host diseaseAllogeneic hematopoietic stem cell transplantationHematopoietic stem cell transplantationStem cell transplantationClostridium difficile infectionAntibiotic prophylaxisOverall survivalCumulative incidenceBloodstream infectionsCell transplantationAntibiotic treatmentCumulative incidence of acute GVHD grades II-IVSevere chronic graft-versus-host diseaseRisk of graft-versus-host diseaseAcute GVHD grade II-IVGVHD grade II-IVDuration of antibiotic therapyRisk of infection-related mortalityPre-engraftment periodGrade II-IVMedian Follow-UpInfection-related mortalityThe Spectrum of CAR Cellular Effectors: Modes of Action in Anti-Tumor Immunity
Nguyen N, Müller R, Briukhovetska D, Weber J, Feucht J, Künkele A, Hudecek M, Kobold S. The Spectrum of CAR Cellular Effectors: Modes of Action in Anti-Tumor Immunity. Cancers 2024, 16: 2608. PMID: 39061247, PMCID: PMC11274444, DOI: 10.3390/cancers16142608.Peer-Reviewed Original ResearchCAR-T cellsLimitations of CAR-T cellsChimeric antigen receptor T cellsBiology of solid tumorsAdoptive cell therapyAnti-tumor immunityCo-stimulatory domainTransgenic cytokinesHLA incompatibilityMode of actionNK cellsHLA compatibilitySwitch receptorsDendritic cellsTumor microenvironmentHematologic neoplasiaT cellsHematological tumorsSolid tumorsImmune cellsAntigen presentationCell therapyCAR activationCellular vehiclesResponse rate
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