Mary Lou (Maria Lucia) Gaeta, MD, JD
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About
Appointments
Pediatric Critical Care Medicine
Assistant Clinical ProfessorPrimary
Other Departments & Organizations
- Pediatric Critical Care Medicine
- Pediatric Hospitalist Program
- Pediatric Intensive Care Unit
- Program for Biomedical Ethics
- Yale Medicine
Education & Training
- JD
- University of Connecticut School of Law (2015)
- MD
- University of Torino (1993)
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Mary Lou (Maria Lucia) Gaeta's published research.
Publications Timeline
A big-picture view of Mary Lou (Maria Lucia) Gaeta's research output by year.
Jordan Pober, MD, PhD
7Publications
246Citations
Publications
2004
Octreotide and low-fat breast milk in postoperative chylothorax
Hamdan M, Gaeta M. Octreotide and low-fat breast milk in postoperative chylothorax. The Annals Of Thoracic Surgery 2004, 77: 2215-2217. PMID: 15172311, DOI: 10.1016/s0003-4975(03)01464-4.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and Concepts
2003
Histamine Antagonizes Tumor Necrosis Factor (TNF) Signaling by Stimulating TNF Receptor Shedding from the Cell Surface and Golgi Storage Pool*
Wang J, Al-Lamki RS, Zhang H, Kirkiles-Smith N, Gaeta ML, Thiru S, Pober JS, Bradley JR. Histamine Antagonizes Tumor Necrosis Factor (TNF) Signaling by Stimulating TNF Receptor Shedding from the Cell Surface and Golgi Storage Pool*. Journal Of Biological Chemistry 2003, 278: 21751-21760. PMID: 12646554, DOI: 10.1074/jbc.m212662200.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsMeSH KeywordsADAM ProteinsADAM17 ProteinAnimalsBrefeldin ACell MembraneCell SeparationCells, CulturedDose-Response Relationship, DrugEndothelium, VascularEnzyme InhibitorsEnzyme-Linked Immunosorbent AssayFlow CytometryGolgi ApparatusHistamineHumansI-kappa B ProteinsImmunoblottingImmunohistochemistryMetalloendopeptidasesMiceMicroscopy, ConfocalMicroscopy, ElectronMicroscopy, FluorescenceMitogen-Activated Protein Kinase 3Mitogen-Activated Protein KinasesNF-KappaB Inhibitor alphaNitric Oxide SynthaseRecombinant Fusion ProteinsReverse Transcriptase Polymerase Chain ReactionSignal TransductionSkinTime FactorsTumor Necrosis Factor-alphaConceptsTumor necrosis factorEndothelial cellsNecrosis factorNovel anti-inflammatory activityPro-inflammatory functionsAnti-inflammatory activityTNF-alpha-converting enzymeEndothelial adhesion moleculesCultured human endothelial cellsTNF-alpha protease inhibitorVascular endothelial cellsCultured endothelial cellsHuman endothelial cellsHistamine injectionH1 receptorsReceptor lossCell surfaceImmunodeficient miceMitogen-activated protein kinase pathwaySurface TNFR1TNF receptorShed receptorCell surface receptorsTNF actionTransient loss
2000
Caveolin-1 Associates with TRAF2 to Form a Complex That Is Recruited to Tumor Necrosis Factor Receptors*
Feng X, Gaeta M, Madge L, Yang J, Bradley J, Pober J. Caveolin-1 Associates with TRAF2 to Form a Complex That Is Recruited to Tumor Necrosis Factor Receptors*. Journal Of Biological Chemistry 2000, 276: 8341-8349. PMID: 11112773, DOI: 10.1074/jbc.m007116200.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCaveolin-1Confocal fluorescence microscopyIntracellular regionNecrosis factor receptor-associated factor 2TNF receptor 2Receptor-associated factor 2TNF receptor 1Promoter-reporter geneCaveolin-1 associatesFluorescence microscopyProtein caveolin-1Caveolin-1 proteinHuman embryonic kidney 293 cellsIntracellular adapter proteinEmbryonic kidney 293 cellsAbsence of ligandRegions of enrichmentKidney 293 cellsEndogenous TRAF2HEK-293 cellsAdapter proteinCultured human umbilical vein endothelial cellsHuman umbilical vein endothelial cellsPlasma membraneUmbilical vein endothelial cellsThe Death Domain of Tumor Necrosis Factor Receptor 1 Is Necessary but Not Sufficient for Golgi Retention of the Receptor and Mediates Receptor Desensitization
Gaeta M, Johnson D, Kluger M, Pober J. The Death Domain of Tumor Necrosis Factor Receptor 1 Is Necessary but Not Sufficient for Golgi Retention of the Receptor and Mediates Receptor Desensitization. Laboratory Investigation 2000, 80: 1185-1194. PMID: 10950109, DOI: 10.1038/labinvest.3780126.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsDeath domainGolgi retentionPlasma membraneC-terminal death domainGolgi apparatusNF-kappaBDominant negative inhibitorWild-type receptorDisparate localizationTNF responseIntracellular domainC-terminusEndothelial cellsNegative inhibitorTNF signalsWild typeTumor necrosis factor receptor 1Chimeric receptorsFactor receptor 1Necrosis factor receptor 1Endogenous receptorsBasal expressionReceptor moleculesType receptorTNF action
1999
The Death Domain of Tumor Necrosis Factor Receptor 1 Is Necessary but Not Sufficient for Golgi Retention in Endothelial Cells
Gaeta M, Johnson D, Pober J. The Death Domain of Tumor Necrosis Factor Receptor 1 Is Necessary but Not Sufficient for Golgi Retention in Endothelial Cells. Pediatric Research 1999, 45: 39-39. DOI: 10.1203/00006450-199904020-00238.Peer-Reviewed Original ResearchCitations
1998
Treatment of traumatic brain injury with hypothermia
Biagas K, Gaeta M. Treatment of traumatic brain injury with hypothermia. Current Opinion In Pediatrics 1998, 10: 271-277. PMID: 9716889, DOI: 10.1097/00008480-199806000-00009.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsTraumatic brain injuryBrain injuryAttenuation of injuryEffects of hypothermiaNew effective therapiesSystemic hypothermiaHypothermic therapyClinical trialsEffective therapySuch injuriesLaboratory evidenceHypothermiaInjuryMild formNitric oxideTherapyPutative mechanismsPatientsMolecular mechanismsSustained applicationTreatmentFree radicalsChildrenComplicationsInflammationLocalization of Epitope-tagged Tumor Necrosis Factor Receptors 1 and 2 in Transfected Endothelial Cells • 196
Gaeta M, Johnson D, Kluger M, Pober J. Localization of Epitope-tagged Tumor Necrosis Factor Receptors 1 and 2 in Transfected Endothelial Cells • 196. Pediatric Research 1998, 43: 36-36. DOI: 10.1203/00006450-199804001-00217.Peer-Reviewed Original Research