Voluntary Faculty
Voluntary faculty are typically clinicians or others who are employed outside of the School but make significant contributions to department programs at the medical center or at affiliate institutions.
Voluntary rank detailsMary Daly
Clinical InstructorAbout
Research
Publications
2026
Risks of non-breast, non-ovarian cancers for BRCA1 and BRCA2 pathogenic variant carriers: a prospective cohort study
Yang R, MacInnis R, Milne R, Nguyen-Dumont T, Maxwell W, Genkinger J, Glendon G, Ross E, Andrulis I, Colonna S, Daly M, John E, Kurian A, Terry M, Hopper J, Southey M, Phillips K, Li S. Risks of non-breast, non-ovarian cancers for BRCA1 and BRCA2 pathogenic variant carriers: a prospective cohort study. BMC Medicine 2026 PMID: 41776557, DOI: 10.1186/s12916-026-04753-8.Peer-Reviewed Original ResearchStandardized incidence ratioBRCA2 PV carriersNon-ovarian cancersBreast Cancer Family RegistryCumulative risk to agePV carriersRisk to ageProspective cohort designBRCA2 pathogenic variantsNon-breastPathogenic variantsCancer standardized incidence ratioPancreatic cancerBRCA2 pathogenic variant carriersCancer follow-up studyKathleen Cuningham Foundation Consortium for ResearchCancer Family RegistryFree of cancerProspective risk estimatesRisk effect sizeMedian baseline agePathogenic variant carriersFollow-up timeCancer risk assessmentProspective cohort studyEfficacy of a sexual quality of life intervention for couples facing metastatic breast cancer: Results of a randomized controlled trial
Reese J, Zimmaro L, Sorice K, Zhang L, Gorman J, Daly M, Zaleta A, Porter L. Efficacy of a sexual quality of life intervention for couples facing metastatic breast cancer: Results of a randomized controlled trial. Cancer 2026, 132: e70334. PMID: 41722045, PMCID: PMC13006998, DOI: 10.1002/cncr.70334.Peer-Reviewed Original ResearchConceptsPatient psychosocial outcomesPsychosocial outcomesQuality of lifeRandomized Controlled TrialsSexual qualitySexual distressQuality of life interventionsMixed linear regression modelsBreast cancerSexual quality of lifeVideoconference interventionQOL interventionPost-interventionInformation bookletIntervention effectsIntimacy enhancementIntervention mediatorsSexual self-efficacySexual satisfactionLinear regression modelsLife interventionsPatient sexual satisfactionSexual concernsSelf-EfficacyEffect sizeThe childcare gap in Europe: probing policy constructions of work-life balance and parental agency
Daly M, Uzunalioğlu M. The childcare gap in Europe: probing policy constructions of work-life balance and parental agency. Journal Of Family Studies 2026, ahead-of-print: 1-21. DOI: 10.1080/13229400.2026.2626691.Peer-Reviewed Original ResearchChildcare gapParental agencyConstructs of work-life balancePolicy constructionWork-life balance policiesWork-life balanceCountries – BelgiumAutonomous agencyCare policyEarly childhood educationBalance policiesParental choiceCountry groupsEuropean countriesAgenciesPolicyChildcareYoung childrenChildhood educationCountriesConceptual frameworkParentsBelgiumUnpaidEntitlement
2025
OR15-06 Steroids, stress and body mass index interact to accelerate female pubertal development
Houghton L, Wei Y, Wudy S, Hartmann M, Stanczyk F, Knight J, Andrulis I, Bradbury A, Schwartz L, Buys S, Daly M, John E, Chung W, Santella R, Romeo R, Terry M. OR15-06 Steroids, stress and body mass index interact to accelerate female pubertal development. Journal Of The Endocrine Society 2025, 9: bvaf149.1742. PMCID: PMC12543535, DOI: 10.1210/jendso/bvaf149.1742.Peer-Reviewed Original ResearchBody mass indexPre-pubertal levelsPubertal developmentFamily historyElevated metabolitesMass indexHazard ratioBreast cancer family historyElevated body mass indexLevels of estrogen metabolitesBMI z-scoreCancer family historyParticipants' heightConfidence intervalsFemale pubertal developmentLEGACY Girls StudyPubertal Development ScaleSteroid metabolomeBreast developmentThelarcheUrine specimensAge of pubertyPubertal androgensPubertal onsetEstrogen metabolitesProfiling DNA damage response in ATM/BRCA2 carriers to inform hereditary cancer risk.
Dedousis D, Hasan A, Patel K, Czyzewicz P, Devarajan K, Hall M, Daly M, Arora S. Profiling DNA damage response in ATM/BRCA2 carriers to inform hereditary cancer risk. Journal Of Clinical Oncology 2025, 43: 10574-10574. DOI: 10.1200/jco.2025.43.16_suppl.10574.Peer-Reviewed Original ResearchGermline pathogenic variantsCancer-free controlsPeripheral blood monocytesSignificant cut-pointsCRC casesDNA damage responseCut-pointsHereditary cancer riskBenjamini-Hochberg false discovery rate methodTwo-sided Mann-Whitney testHigh-risk familiesSporadic colorectal cancerPreliminary analysis of patientsDiagnosis of cancerAnalysis of patientsHigh-risk populationFalse discovery rate methodCancer riskHigh-risk groupNegative regulator of p53Age-matched controlsDNA repair genesDamage responseMann-Whitney testNon-carrier controlsGirls with high hormonal steroids, BMI and stress reach puberty early
Houghton L, wei Y, Wudy S, hartmann M, stanczyk F, Knight J, andrulis I, Bradbury A, Schwartz L, Buys S, Daly M, John E, Chung W, santella R, Romeo R, Beth T. Girls with high hormonal steroids, BMI and stress reach puberty early. Endocrine Abstracts 2025 DOI: 10.1530/endoabs.110.p991.Peer-Reviewed Original ResearchDoes inclusion of neighborhood variables improve clinical risk prediction for advanced prostate cancer in Black and White men?
Tagai E, Handorf E, Sorice K, Fang C, Deng M, Daly M, Reese A, Henry K, Ragin C, Lynch S. Does inclusion of neighborhood variables improve clinical risk prediction for advanced prostate cancer in Black and White men? Urologic Oncology Seminars And Original Investigations 2025, 43: 334.e17-334.e24. PMID: 40121103, PMCID: PMC12068980, DOI: 10.1016/j.urolonc.2025.02.021.Peer-Reviewed Original ResearchConceptsNeighborhood-level variablesProstate Cancer Prevention TrialNeighborhood variablesProtective service occupationsBlack menNeighborhood-level risk factorsWhite menNeighborhood-level povertyMedical oncology clinicUniversity Health SystemCancer Prevention TrialRisk prediction toolsLogistic regression modelsRisk prediction modelSocial environmental variablesPatients' medical recordsService occupationsHigh-grade PCaCurrent risk prediction modelsHealth systemPersistent disparitiesOncology clinicInsurance statusAssociated with ratesClinical risk prediction
2024
Changes in Risk Tolerance for Ovarian Cancer Prevention Strategies during the COVID-19 Pandemic: Results of a Discrete Choice Experiment
Egleston B, Daly M, Lew K, Bealin L, Husband A, Stopfer J, Przybysz P, Tchuvatkina O, Wong Y, Garber J, Rebbeck T. Changes in Risk Tolerance for Ovarian Cancer Prevention Strategies during the COVID-19 Pandemic: Results of a Discrete Choice Experiment. Medical Decision Making 2024, 45: 168-176. PMID: 39722532, PMCID: PMC11881031, DOI: 10.1177/0272989x241302829.Peer-Reviewed Original ResearchConceptsHigher ovarian cancer riskRisk of ovarian cancerRisk-reducing surgeryOvarian cancer riskCancer prevention strategiesCancer riskPrevention strategiesOvarian cancerOvarian cancer prevention strategiesElevated risk of breastRisk of breastCOVID-19 pandemicPrevention scenariosInfluence patients' decisionsRisk-reducing strategiesMedical decision makingAge of menopauseDiscrete choice experimentPatient's decisionElevated riskGenetic testingCOVID-19Menopausal symptomsMedical CenterHeart diseaseEfficacy of a couple‐based intervention addressing sexual concerns for breast cancer survivors: Results of a randomized controlled trial
Reese J, Lepore S, Sorice K, Zimmaro L, Hasler J, Handorf E, Daly M, Zaleta A, Westbrook K, Porter L. Efficacy of a couple‐based intervention addressing sexual concerns for breast cancer survivors: Results of a randomized controlled trial. Cancer 2024, 131: e35685. PMID: 39645589, PMCID: PMC11696781, DOI: 10.1002/cncr.35685.Peer-Reviewed Original ResearchBreast cancer survivorsCouple-based interventionsActive control interventionCancer survivorsSexual concernsRandomized Controlled TrialsIE interventionIntervention effectsIntimacy enhancementEstimates of intervention effectsMixed linear regression modelsSexual functionSurvivors 3 monthsLinear regression modelsLive HealthyFour-sessionIE sessionControl interventionsSecondary outcomesInterventionSatisfaction rateShort-term benefitsSexual adjustmentSurvivorsOverall sexual functionMenopausal hormone therapy: assessing associations with breast and colorectal cancers by familial risk
Macinnis R, Jenkins M, Milne R, John E, Daly M, Andrulis I, Colonna S, Phillips K, Investigators K, Le Marchand L, Newcomb P, Phipps A, Schmit S, Macrae F, Buchanan D, Gallinger S, Pai R, Samadder N, Giles G, Southey M, Hopper J, Terry M. Menopausal hormone therapy: assessing associations with breast and colorectal cancers by familial risk. JNCI Cancer Spectrum 2024, 9: pkae121. PMID: 39673461, PMCID: PMC11700558, DOI: 10.1093/jncics/pkae121.Peer-Reviewed Original ResearchFamily risk scoreMenopausal hormone therapyFamilial riskHazard ratioColorectal cancerFamilial risk of BCBreast cancerFamily historyDecreased colorectal cancerCancer family historyRisk of BCIncreased breast cancerAssociated with breastIncident BCNever usersGeneral populationRisk scoreHarmonized dataWomenHormone therapyRiskAssociationCancerNeverCohort
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