Layne Dylla

Stroke is a leading cause of death and disability worldwide. Infections following a stroke account for approximately 1/3 of all stroke deaths. Dr. Dylla's research focuses on understanding the pathophysiology of stroke and how this understanding can be used to advance patient care in the prehospital and emergency department (ED) settings. This includes developing analysis of the early immune response, and early metabolomic and epigenomic changes in response to stroke that can lead to immunosuppression and post-stroke infections. Additionally, Dr. Dylla seeks to improve patient outcomes through analysis of prehospital and ED stroke care, working to develop easy acute interventions to promote early stroke recognition by EMS and rapid transport to a certified stroke center.

As Director of the Emergency Medicine Specimen Biobank (EMSB), Dr. Dylla oversees collection of blood, urine, and saliva samples from ED patients. This biobank supports additional research in acute care. It is crucial for facilitating critical research in the ED while ensuring safe and ethical patient enrollment. This biorepository currently supports additional research collaborations in cardiac arrest outcomes, post-concussive syndrome, infection response, post-stroke treatment approaches, cardiac ischemia pathophysiology, and diagnostics for aortic dissection. The EMSB continues to seek opportunities for additional collaborations that improve patient outcomes.

As Co-Director of the Emergency Medicine Research and Growth Experience (EMERGE) Program, Dr. Dylla connects investigators with pre-trained, research-ready postgraduates embedded in the ED, delivering dependable support for participant screening, enrollment, and data collection. EMERGE advances the practice of emergency medicine through cutting-edge research that impacts real patients and clinical practice. It also provides a mechanism for postgraduate students to gain research experience, mentorship, and prepare for exciting healthcare careers.