Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsLauren Sippel, PhD
About
Research
Publications
2024
Novel Pharmacologic and Other Somatic Treatment Approaches for Posttraumatic Stress Disorder in Adults: State of the Evidence
Sippel L, Hamblen J, Kelmendi B, Alpert J, Carpenter L, Grzenda A, Kraguljac N, McDonald W, Rodriguez C, Widge A, Nemeroff C, Schnurr P, Holtzheimer P, Biomarkers and Treatments T. Novel Pharmacologic and Other Somatic Treatment Approaches for Posttraumatic Stress Disorder in Adults: State of the Evidence. American Journal Of Psychiatry 2024, 181: 1045-1058. PMID: 39616450, DOI: 10.1176/appi.ajp.20230950.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderStress disorderPathophysiology of posttraumatic stress disorderNon-trauma-focused psychotherapyTrauma-focused psychotherapySomatic treatment approachesEvidence-based treatmentsAntidepressant medicationSomatic treatmentsPsychiatric disordersSomatic interventionsTranscranial magnetic stimulationPsychotherapyMagnetic stimulationTreatment approachesDisordersRecommended first-line treatmentAdultsFirst-line treatmentMedicationMechanism of actionMonotherapy strategySalienceSpecific treatmentEvidenceExamining the impact of brief couples‐based posttraumatic stress disorder treatments on anger and psychological aggression in veterans and their partners
Wells S, Knopp K, Wachsman T, Dillon K, Walker H, Sippel L, Morland L, Glassman L. Examining the impact of brief couples‐based posttraumatic stress disorder treatments on anger and psychological aggression in veterans and their partners. Journal Of Traumatic Stress 2024, 38: 165-173. PMID: 39318041, PMCID: PMC11794020, DOI: 10.1002/jts.23099.Peer-Reviewed Original ResearchPosttraumatic stress disorderPsychological aggressionCouples-based interventionsCognitive-behavioral conjoint therapyPosttraumatic stress disorder treatmentIntimate partnersVeterans' mental healthAngry temperamentInterpersonal functioningConjoint therapyAnger symptomsStress disorderDisorder treatmentAngerEffect sizeMental healthAggressionVeteransTreatment conditionsActive comparatorPosttreatmentImprove aspectsLoved onesTemperamentPartnersDesign of a randomized clinical trial of brief couple therapy for PTSD augmented with intranasal oxytocin
Sippel L, Wachsman T, Kelley M, Knopp K, Khalifian C, Maglione J, Glynn S, Macdonald A, Monson C, Flanagan J, Holtzheimer P, Morland L. Design of a randomized clinical trial of brief couple therapy for PTSD augmented with intranasal oxytocin. Contemporary Clinical Trials 2024, 141: 107534. PMID: 38614447, DOI: 10.1016/j.cct.2024.107534.Peer-Reviewed Original ResearchConceptsCognitive-behavioral conjoint therapyImproving posttraumatic stress disorderPosttraumatic stress disorderIntranasal oxytocinConjoint therapyMechanisms of posttraumatic stress disorderRelationship qualityInternational units of oxytocinVA San Diego Healthcare SystemMechanisms of changeCognitive-behavioralStress disorderCouple therapyRelationship satisfactionManual treatmentPreliminary evidenceIntimate relationshipsOxytocinPotential mechanisms of actionVeteransSelf-reported communication skillsPlaceboRandomized clinical trialsCommunication skillsClinical trialsSources of Social Support and Trauma Recovery: Evidence for Bidirectional Associations from a Recently Trauma-Exposed Community Sample
Sippel L, Liebman R, Schäfer S, Ennis N, Mattern A, Rozek D, Monson C. Sources of Social Support and Trauma Recovery: Evidence for Bidirectional Associations from a Recently Trauma-Exposed Community Sample. Behavioral Sciences 2024, 14: 284. PMID: 38667080, PMCID: PMC11047467, DOI: 10.3390/bs14040284.Peer-Reviewed Original ResearchPost-traumatic stress disorderPost-traumatic stress disorder symptomsSevere PTSD symptomsSources of social supportPTSD symptomsSocial supportMeasures of post-traumatic stress disorderPost-traumatic stress disorder severityRandom intercept cross-lagged panel modelTrauma-exposed community sampleTrauma recoveryCross-lagged panel modelLevels of post-traumatic stress disorderWithin-person increasesCross-lagged coefficientsPerceived Social SupportExposed to traumaIntimate partnersIntimate partner supportTrauma-exposedRI-CLPMStress disorderCommunity sampleBidirectional associationsCommunity individualsSustaining the collaborative chronic care model in outpatient mental health: a matrixed multiple case study
Kim B, Sullivan J, Brown M, Connolly S, Spitzer E, Bailey H, Sippel L, Weaver K, Miller C. Sustaining the collaborative chronic care model in outpatient mental health: a matrixed multiple case study. Implementation Science 2024, 19: 16. PMID: 38373979, PMCID: PMC10875770, DOI: 10.1186/s13012-024-01342-2.Peer-Reviewed Original ResearchConceptsCollaborative chronic care modelEvidence-based practiceChronic Care ModelOutpatient mental health clinicMental health clinicsCare modelHealth clinicsVeterans AffairsEvidence-based Collaborative Chronic Care ModelDepartment of Veterans AffairsIntegrated Promoting ActionOutpatient mental healthCare qualityProvider interviewsHealth disparitiesImplementation trialInternal facilitatorsHealth servicesInfluence implementationProvider collaborationMental healthResearch implementationImplementation supportClinical spaceInterdisciplinary coordinationAdaptation for sustainability in an implementation trial of team-based collaborative care
Miller C, Sullivan J, Connolly S, Richardson E, Stolzmann K, Brown M, Bailey H, Weaver K, Sippel L, Kim B. Adaptation for sustainability in an implementation trial of team-based collaborative care. Implementation Research And Practice 2024, 5: 26334895231226197. PMID: 38322803, PMCID: PMC10807389, DOI: 10.1177/26334895231226197.Peer-Reviewed Original ResearchEvidence-based practiceCollaborative chronic care modelImplementation facilitatorsCare practicesImplementation trialTeam-based collaborative careAdaptation of evidence-based practicesEvidence-based practice sustainabilityImplementation strategiesChronic Care ModelMental health teamsClinical care practicesPublic health endeavorsCollaborative careCare modelHealth teamsHealthcare interventionsInternal facilitatorsHealth endeavorsImprove healthcareImplementation timeframeConsensus processFacilitation supportMedical CenterQualitative data
2023
An examination of relationship satisfaction as a predictor of outcomes of brief couple therapy for posttraumatic stress disorder
Sippel L, Knopp K, Wachsman T, Khalifian C, Glynn S, Morland L. An examination of relationship satisfaction as a predictor of outcomes of brief couple therapy for posttraumatic stress disorder. Journal Of Traumatic Stress 2023, 36: 1115-1125. PMID: 37898980, DOI: 10.1002/jts.22984.Peer-Reviewed Original ResearchConceptsRelationship satisfactionBaseline relationship satisfactionPsychosocial functioningCouple therapyCognitive-behavioral conjoint therapyBehavioral Conjoint TherapyPTSD symptom severityPosttraumatic stress disorderBrief Couple TherapyRelationship distressDyadic treatmentPTSD symptomsConjoint therapyStress disorderDistressed individualsDistressed rangeCAPS-5Military veteransSymptom severityPTSDSatisfactionIntimate relationshipsFunctioningTreatment conditionsFamily education
2018
Negatively Biased Emotion Perception in Depression as a Contributing Factor to Psychological Aggression Perpetration: A Preliminary Study
Marshall A, Sippel L, Belleau E. Negatively Biased Emotion Perception in Depression as a Contributing Factor to Psychological Aggression Perpetration: A Preliminary Study. 2018, 220-234. DOI: 10.4324/9781315100319-15.Peer-Reviewed Original ResearchPsychological aggression perpetrationIntimate partner aggression (IPA) perpetrationNegative social stimuliPartner aggression perpetrationAggression perpetrationSocial stimuliEmotional expressionBiased perceptionElevated depressive symptomsValence ratingsFacial expressionsDepressive symptomsEmotional facial expressionsNegative emotional expressionsSad emotional expressionsCurrent relationshipEmotion perceptionEmotional stimuliRelationship behaviorsInformation processingUniversity studentsPerpetrationStimuliPerceptionPrior research
2016
The burden of hostility in U.S. Veterans: Results from the National Health and Resilience in Veterans Study
Sippel LM, Mota NP, Kachadourian LK, Krystal JH, Southwick SM, Harpaz-Rotem I, Pietrzak RH. The burden of hostility in U.S. Veterans: Results from the National Health and Resilience in Veterans Study. Psychiatry Research 2016, 243: 421-430. PMID: 27450745, DOI: 10.1016/j.psychres.2016.06.040.Peer-Reviewed Original ResearchConceptsS. veteransLongitudinal courseNational HealthProtective correlatesVeterans StudyProspective cohort studyPopulation-based evaluationPopulation-based dataAggressive urgesMajority of veteransPhysical health consequencesProtective psychosocial characteristicsCohort studySymptomatic courseAlcohol misuseU.S. veteransPsychosocial characteristicsHealth consequencesTreatment effortsPsychological distressVeteransTwo-year periodPrevalenceRiskSocial connectednessAn examination of the roles of trauma exposure and posttraumatic stress disorder on emotion regulation strategies of Operation Iraqi Freedom, Operation Enduring Freedom, and Operation New Dawn veterans
Sippel LM, Roy AM, Southwick SM, Fichtenholtz HM. An examination of the roles of trauma exposure and posttraumatic stress disorder on emotion regulation strategies of Operation Iraqi Freedom, Operation Enduring Freedom, and Operation New Dawn veterans. Cognitive Behaviour Therapy 2016, 45: 339-350. PMID: 27195939, DOI: 10.1080/16506073.2016.1183037.Peer-Reviewed Original ResearchConceptsOIF/OEF/OND veteransPosttraumatic stress disorderEmotion regulation strategiesOperation New Dawn veteransTrauma exposureNew Dawn veteransEmotion regulationRegulation strategiesComparison participantsStress disorderMaintenance of PTSDAdaptive emotion regulation strategiesOperation Enduring FreedomEmotion regulation difficultiesEmotion Regulation QuestionnaireEmotion regulation skillsEmotion Regulation ScaleHealthy comparison participantsTrauma-exposed veteransOperation Iraqi FreedomCombat trauma exposureEnduring FreedomIraqi FreedomCognitive reappraisalExpressive suppression