Joseph Schindler, MD
Professor of Neurology & NeurosurgeryCards
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Director, Yale New Haven Telestroke Service, Neurology
Clinical Chief, Division of Vascular Neurology, Neurology
Director, Yale New Haven Comprehensive Stroke Center, Neurology
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Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileAdditional Titles
Director, Yale New Haven Telestroke Service, Neurology
Clinical Chief, Division of Vascular Neurology, Neurology
Director, Yale New Haven Comprehensive Stroke Center, Neurology
Contact Info
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileAdditional Titles
Director, Yale New Haven Telestroke Service, Neurology
Clinical Chief, Division of Vascular Neurology, Neurology
Director, Yale New Haven Comprehensive Stroke Center, Neurology
Contact Info
About
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Titles
Professor of Neurology & Neurosurgery
Director, Yale New Haven Telestroke Service, Neurology; Clinical Chief, Division of Vascular Neurology, Neurology; Director, Yale New Haven Comprehensive Stroke Center, Neurology
Appointments
Neurology
ProfessorFully JointNeurosurgery
ProfessorFully Joint
Other Departments & Organizations
- Neurology
- Neurosurgery
- Stroke Center
- Stroke Telemedicine Program
- Vascular Neurology
- Yale Medicine
- Yale Ventures
Education & Training
- Chief Resident
- Yale University School of Medicine (2005)
- Resident
- Yale New Haven Hopsital (2004)
- Resident
- Yale University School of Medicine (2002)
- MD
- Tufts University School of Medicine (2001)
- BA
- Tufts University (1994)
Research
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Overview
Medical Research Interests
ORCID
0000-0003-2865-0438
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Lauren Hachmann Sansing, MD, MS, FAHA, FANA
Charles Wira, MD
Kevin Sheth, MD
Guido J. Falcone, MD, ScD, MPH
Charles Matouk, MD
Nils Petersen, MD, PhD, MSc
Publications
2025
Carotid Revascularization in the Modern Era: A Comparative Review of Carotid Endarterectomy, Carotid Angioplasty and Stenting, and Transcarotid Artery Revascularization
Amllay A, Koo A, Renedo D, Padmanaban V, Teasdale B, Hebert R, Arat A, Duda T, Schindler J, Stapleton C, Rabinov J, Patel A, Matouk C, Sujijantarat N. Carotid Revascularization in the Modern Era: A Comparative Review of Carotid Endarterectomy, Carotid Angioplasty and Stenting, and Transcarotid Artery Revascularization. Seminars In Neurology 2025 PMID: 40889763, DOI: 10.1055/a-2685-3141.Peer-Reviewed Original ResearchConceptsTranscarotid artery revascularizationCarotid endarterectomyArtery revascularizationCarotid angioplastyRevascularization strategyIndividual risk-benefit assessmentTF-CASOptimal medical therapyGold standard procedureCarotid artery stenosisCompared to carotid endarterectomyAcute ischemic strokeRisk-benefit assessmentAsymptomatic patientsSymptomatic patientsSurgical riskCarotid revascularization strategiesMedical therapySurgical interventionSurgical techniqueCarotid revascularizationClinical indicationsArtery stenosisRevascularizationPatientsMechanical thrombectomy in centenarians for the treatment of acute stroke: Report of 4 patients and review of the literature
Arat A, Amllay A, Yilmaz E, Desai K, Matouk C, Schindler J. Mechanical thrombectomy in centenarians for the treatment of acute stroke: Report of 4 patients and review of the literature. Radiology Case Reports 2025, 20: 3938-3944. PMID: 40496084, PMCID: PMC12149959, DOI: 10.1016/j.radcr.2025.04.095.Peer-Reviewed Original ResearchConceptsIntracranial large vessel occlusionLarge vessel occlusionMechanical thrombectomyClinical outcomesAcute intracranial large vessel occlusionVessel occlusionPrestroke mRS scorePrestroke modified Rankin ScaleMechanical thrombectomy outcomesTreatment of acute strokeEndovascular treatmentArtery thrombectomyMRS scoreClinical complicationsElderly patientsRankin ScaleAcute infarctionPatientsThrombectomyResidual deficitsDistal embolizationAcute strokeCerebral thrombectomyThrombectomy outcomesUpper age limit
2024
Neighborhood Deprivation and Functional Outcomes Following Ischemic Stroke (P2-4.007)
Kleinberg L, Clocchiatti-Tuozzo S, Rivier C, Torres-Lopez V, Kim J, Kitlen E, Kampp M, Jasak S, Schindler J, Sansing L, Sheth K, Falcone G. Neighborhood Deprivation and Functional Outcomes Following Ischemic Stroke (P2-4.007). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205095.Peer-Reviewed Original Research
2023
Association of Neighborhood-Level Socioeconomic Factors With Delay to Hospital Arrival in Patients With Acute Stroke
Forman R, Okumu R, Mageid R, Baker A, Neu D, Parker R, Peyravi R, Schindler J, Sansing L, Sheth K, de Havenon A, Jasne A, Narula R, Wira C, Warren J, Sharma R. Association of Neighborhood-Level Socioeconomic Factors With Delay to Hospital Arrival in Patients With Acute Stroke. Neurology 2023, 102: e207764. PMID: 38165368, PMCID: PMC10834135, DOI: 10.1212/wnl.0000000000207764.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsEmergency department arrival timesEmergency medical servicesLate presentationAcute ischemic stroke therapyYale-New Haven HospitalGuidelines-Stroke registryNeighborhood-level socioeconomic factorsPatient-level factorsRetrospective observational studyIschemic stroke therapyMixed-effects logistic regression modelNon-white patientsNon-white raceUnivariate logistic regressionNew Haven HospitalLogistic regression modelsHospital presentationTreatment ineligibilityStroke RegistryAcute strokeHospital arrivalStroke therapyUnivariate analysisObservational studyPatients
2022
Poor Collaterals and Rapid Early Infarct Progression Are Associated With Increased Vulnerability to Blood Pressure Reductions (S21.002)
Begunova Y, Bartolome D, Kobsa J, Soto A, Prasad A, Galecio M, Vivanco-Suarez J, Quispe-Orozco D, Farooqui M, Sansing L, Schindler J, De Havenon A, Matouk C, Sheth K, Ortega-Gutierrez S, Petersen N. Poor Collaterals and Rapid Early Infarct Progression Are Associated With Increased Vulnerability to Blood Pressure Reductions (S21.002). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.3104.Peer-Reviewed Original ResearchPortable, low-field magnetic resonance imaging enables highly accessible and dynamic bedside evaluation of ischemic stroke
Yuen MM, Prabhat AM, Mazurek MH, Chavva IR, Crawford A, Cahn BA, Beekman R, Kim JA, Gobeske KT, Petersen NH, Falcone GJ, Gilmore EJ, Hwang DY, Jasne AS, Amin H, Sharma R, Matouk C, Ward A, Schindler J, Sansing L, de Havenon A, Aydin A, Wira C, Sze G, Rosen MS, Kimberly WT, Sheth KN. Portable, low-field magnetic resonance imaging enables highly accessible and dynamic bedside evaluation of ischemic stroke. Science Advances 2022, 8: eabm3952. PMID: 35442729, PMCID: PMC9020661, DOI: 10.1126/sciadv.abm3952.Peer-Reviewed Original ResearchCitationsAltmetricConceptsIschemic strokeMagnetic resonance imagingResonance imagingFluid-attenuated inversion recoveryDiffusion-weighted imaging sequencesStroke volume measurementsStroke pathwayStroke severityFunctional outcomeLow-field magnetic resonance imagingBedside evaluationClinical managementStroke volumeMRI studiesStrokePatientsBrain imagingCerebellar structuresHigh-field MRI studiesHyperintense regionsInversion recoveryInfarctsUseful imagingVolume measurementsAcute Ischemic Stroke, Depressed Left Ventricular Ejection Fraction, and Sinus Rhythm: Prevalence and Practice Patterns
Baker AD, Schwamm LH, Sanborn DY, Furie K, Stretz C, Mac Grory B, Yaghi S, Kleindorfer D, Sucharew H, Mackey J, Walsh K, Flaherty M, Kissela B, Alwell K, Khoury J, Khatri P, Adeoye O, Ferioli S, Woo D, Martini S, La Rosa F, Demel SL, Madsen T, Star M, Coleman E, Slavin S, Jasne A, Mistry EA, Haverbusch M, Merkler AE, Kamel H, Schindler J, Sansing LH, Faridi KF, Sugeng L, Sheth KN, Sharma R. Acute Ischemic Stroke, Depressed Left Ventricular Ejection Fraction, and Sinus Rhythm: Prevalence and Practice Patterns. Stroke 2022, 53: 1883-1891. PMID: 35086361, PMCID: PMC10214981, DOI: 10.1161/strokeaha.121.036706.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsLeft ventricular ejection fractionAcute ischemic strokeDepressed left ventricular ejection fractionVentricular ejection fractionSinus rhythmIschemic strokeEjection fractionPooled prevalenceHealth Stroke Severity ScaleSecondary stroke prevention strategiesMultivariable logistic regression modelAntithrombotic treatment regimensHospital-based cohortRetrospective cohort studySecondary stroke preventionStroke prevention strategiesMulti-center cohortStroke Severity ScaleLogistic regression modelsEchocardiographic characteristicsHospitalization dischargeAntiplatelet therapyStroke preventionCardiac thrombusCohort studyBedside detection of intracranial midline shift using portable magnetic resonance imaging
Sheth KN, Yuen MM, Mazurek MH, Cahn BA, Prabhat AM, Salehi S, Shah JT, By S, Welch EB, Sofka M, Sacolick LI, Kim JA, Payabvash S, Falcone GJ, Gilmore EJ, Hwang DY, Matouk C, Gordon-Kundu B, RN AW, Petersen N, Schindler J, Gobeske KT, Sansing LH, Sze G, Rosen MS, Kimberly WT, Kundu P. Bedside detection of intracranial midline shift using portable magnetic resonance imaging. Scientific Reports 2022, 12: 67. PMID: 34996970, PMCID: PMC8742125, DOI: 10.1038/s41598-021-03892-7.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMidline shiftNeuroscience intensive care unitCare measurementYale-New Haven HospitalValuable bedside toolIntensive care unitPoor clinical outcomeBrain-injured patientsMass effectNew Haven HospitalMagnetic resonance imagingClinical outcomesIll patientsCare unitStroke patientsFunctional outcomeBedside toolObservational studyBedside detectionImaging examsPatientsResonance imagingPortable MRIImaging suiteSignificant concordance
2021
Prior Stroke and Age Predict Acute Ischemic Stroke Among Hospitalized COVID-19 Patients: A Derivation and Validation Study
Peng TJ, Jasne AS, Simonov M, Abdelhakim S, Kone G, Cheng YK, Rethana M, Tarasaria K, Herman AL, Baker AD, Yaghi S, Frontera JA, Sansing LH, Falcone GJ, Spudich S, Schindler J, Sheth KN, Sharma R. Prior Stroke and Age Predict Acute Ischemic Stroke Among Hospitalized COVID-19 Patients: A Derivation and Validation Study. Frontiers In Neurology 2021, 12: 741044. PMID: 34675873, PMCID: PMC8524436, DOI: 10.3389/fneur.2021.741044.Peer-Reviewed Original ResearchCitationsAltmetricConceptsAcute ischemic strokeHospitalized COVID-19 patientsCOVID-19 patientsCOVID-19 cohortNeurologic symptomsPrior strokeIschemic strokeAIS patientsDerivation cohortControl cohortRisk of AISMultivariable logistic regression modelIschemic stroke riskCOVID-19 severityYale New Haven HealthLogistic regression modelsHospital presentationIndependent predictorsStroke riskMajor health systemsHigh riskPatientsYounger ageCohortStrokePortable, bedside, low-field magnetic resonance imaging for evaluation of intracerebral hemorrhage
Mazurek MH, Cahn BA, Yuen MM, Prabhat AM, Chavva IR, Shah JT, Crawford AL, Welch EB, Rothberg J, Sacolick L, Poole M, Wira C, Matouk CC, Ward A, Timario N, Leasure A, Beekman R, Peng TJ, Witsch J, Antonios JP, Falcone GJ, Gobeske KT, Petersen N, Schindler J, Sansing L, Gilmore EJ, Hwang DY, Kim JA, Malhotra A, Sze G, Rosen MS, Kimberly WT, Sheth KN. Portable, bedside, low-field magnetic resonance imaging for evaluation of intracerebral hemorrhage. Nature Communications 2021, 12: 5119. PMID: 34433813, PMCID: PMC8387402, DOI: 10.1038/s41467-021-25441-6.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMagnetic resonance imagingNIH Stroke ScaleIntracerebral hemorrhageHematoma volumeYale-New Haven HospitalStroke care pathwayConventional magnetic resonance imagingBoard-certified neuroradiologistsNew Haven HospitalResource-limited settingsStroke ScaleClinical outcomesLow-field magnetic resonance imagingCare pathwayLow-field magnetic resonanceRadiological examinationConventional neuroimagingAdvanced MRI technologiesResonance imagingCases of disagreementHemorrhageMRI technologyPortable MRINeuroimagingMagnetic resonance
Clinical Trials
Current Trials
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis (CAPTIVA)
HIC ID2000031893RoleSub InvestigatorPrimary Completion Date03/07/2028Recruiting ParticipantsGenderBothAge30 years - 80 yearsAnticoagulation for Stroke Prevention and Recovery After ICH (ASPIRE)
HIC ID2000026409RoleSub InvestigatorPrimary Completion Date04/30/2028Recruiting ParticipantsGenderBothAge18+ yearsTransforming Acute Stroke Detection through Real Time Neurological Monitoring
HIC ID1605017863RoleSub InvestigatorPrimary Completion Date07/01/2017Recruiting ParticipantsGenderBothAge18+ years
Academic Achievements & Community Involvement
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Honors
honor Connecticut Magazine Top Docs 2016
04/01/2016Regional AwardConnecticut MagazineDetailsUnited Stateshonor Connecticut Magazine Top Docs 2015
04/03/2015Regional AwardConnecticut MagazineDetailsUnited States
Clinical Care
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Overview
Joseph Schindler, MD, is the clinical chief of Vascular Neurology and the director of Yale New Haven Comprehensive Stroke Center. Additionally he is the director of the Telestroke Service.
Clinical Specialties
Fact Sheets
Transient Ischemic Attack
Learn More on Yale MedicineIschemic Stroke
Learn More on Yale MedicineHemorrhagic Stroke
Learn More on Yale MedicineStroke
Learn More on Yale Medicine
Board Certifications
Vascular Neurology
- Certification Organization
- AB of Psychiatry & Neurology
- Latest Certification Date
- 2019
- Original Certification Date
- 2009
Neurology
- Certification Organization
- AB of Psychiatry & Neurology
- Latest Certification Date
- 2018
- Original Certification Date
- 2008
Yale Medicine News
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Contacts
Locations
Hunter Building
Academic Office
15 York Street, Ste 905
New Haven, CT 06510
Appointments
203.737.1057Patient Care Locations
Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.