Jonathan Alderman
Research Associate ImmunobiologyDownloadHi-Res Photo
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Additional Titles
Research Associate, Immunobiology
Contact Info
About
Titles
Research Associate Immunobiology
Research Associate, Immunobiology
Departments & Organizations
- Flavell Lab
- Rheumatic Diseases Research Core
- YCCEH
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Jonathan Alderman's published research.
David Gonzalez
Diane Krause, MD, PhD
Emanuela Bruscia, PhD
Giulia Biancon, PhD
Mina Xu, MD
Stephanie Halene, MD, Dr Med
Publications
2021
Combined liver–cytokine humanization comes to the rescue of circulating human red blood cells
Song Y, Shan L, Gbyli R, Liu W, Strowig T, Patel A, Fu X, Wang X, Xu ML, Gao Y, Qin A, Bruscia EM, Tebaldi T, Biancon G, Mamillapalli P, Urbonas D, Eynon E, Gonzalez DG, Chen J, Krause DS, Alderman J, Halene S, Flavell RA. Combined liver–cytokine humanization comes to the rescue of circulating human red blood cells. Science 2021, 371: 1019-1025. PMID: 33674488, PMCID: PMC8292008, DOI: 10.1126/science.abe2485.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsRed blood cellsBlood cellsHuman sickle cell diseaseSickle cell diseaseImmunodeficient murine modelKupffer cell densityBone marrow failureMISTRG miceIntrasplenic injectionSCD pathologyCell diseaseMurine modelComplement C3RBC survivalVivo modelHuman cytokinesPreclinical testingHematopoietic stem cellsHuman red blood cellsMarrow failureFumarylacetoacetate hydrolase geneHuman erythropoiesisHuman liverHuman hepatocytesMice