Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsHuabing Li, PhD
Assistant Professor AdjunctAbout
Research
Publications
2026
Inhibition of nucleoporin 214 depletes leukemia stem cells by promoting heme catabolism and lipid peroxidation
Chen Z, Wu F, Zhang W, Guo W, Li Y, Gong Q, Wei Y, Li L, Chen T, Zhao X, Xiao J, Zeng H, Deng J, Li H, Wang L, Guo Z, Hou Y. Inhibition of nucleoporin 214 depletes leukemia stem cells by promoting heme catabolism and lipid peroxidation. Blood 2026 PMID: 42640860, DOI: 10.1182/blood.2026033244.Peer-Reviewed Original ResearchNat10-mediated ac4C modification sustains macrophage proliferation and mitigates colitis progression via Mcm2 stabilization
Wang J, Liu T, Zhao J, Diao Z, Fan F, Qin D, Zhang Y, Wang X, Jiang N, Ding C, Li H, Wu Y. Nat10-mediated ac4C modification sustains macrophage proliferation and mitigates colitis progression via Mcm2 stabilization. Science China Life Sciences 2026, 1-13. PMID: 42645676, DOI: 10.1007/s11427-025-3216-5.Peer-Reviewed Original ResearchBlocking the m6Am methyltransferase PCIF1 in macrophages attenuates colitis progression by preventing neuronal damage
Ding C, Zhao J, Zhao T, Xiao Y, Li K, Liu X, Ge X, Qin D, Huang Z, Zhang Y, Liu H, Diao Z, Ye Y, Flavell R, Luo C, Chen S, Yi C, Wang Z, Li H. Blocking the m6Am methyltransferase PCIF1 in macrophages attenuates colitis progression by preventing neuronal damage. Cellular & Molecular Immunology 2026, 1-19. PMID: 42613369, DOI: 10.1038/s41423-026-01459-y.Peer-Reviewed Original ResearchBlocking the m6Am methyltransferase PCIF1 releases STAT1-mediated Th1 immunity to potentiate cancer immunotherapy
Huang J, Zhou J, Liu X, Liu X, Xiao Y, Li K, Ding C, Cai X, Mao W, Xu C, Kong Y, Deng Y, Song X, Yang M, Du D, Guo S, Chen K, Luo C, Yi C, Chen S, Li H. Blocking the m6Am methyltransferase PCIF1 releases STAT1-mediated Th1 immunity to potentiate cancer immunotherapy. Nature Communications 2026, 17: 7412. PMID: 42509238, PMCID: PMC13408595, DOI: 10.1038/s41467-026-75269-1.Peer-Reviewed Original ResearchAuthor Correction: A Treg-specific long noncoding RNA maintains immune-metabolic homeostasis in aging liver
Ding C, Yu Z, Sefik E, Zhou J, Wang G, Li B, Flavell R, Hu W, Ye Y, Li H. Author Correction: A Treg-specific long noncoding RNA maintains immune-metabolic homeostasis in aging liver. Nature Aging 2026, 6: 1734-1734. PMID: 42426234, DOI: 10.1038/s43587-026-01184-1.Commentaries, Editorials and LettersRNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control
Zhang Y, Kan C, Yang X, Hao Y, Cai X, Yang M, Zhang Q, Wang Z, Jiang N, Wang L, Li H, Zhou J. RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control. Advanced Science 2026, 13: e16653. PMID: 42210780, PMCID: PMC13336107, DOI: 10.1002/advs.202516653.Peer-Reviewed Original Researchm6A RNA modification guides alternative polyadenylation to maintain T cell quiescence
Zhang X, Li H, Wang G, Miao S, Hao Y, Li S, Li B, Xiao H, Su B, Wu Y, Ye Y, Li H. m6A RNA modification guides alternative polyadenylation to maintain T cell quiescence. Science Advances 2026, 12: eaea4983. PMID: 42127188, PMCID: PMC13170632, DOI: 10.1126/sciadv.aea4983.Peer-Reviewed Original ResearchtRNA m1A modification orchestrates STING translation in macrophages to enhance antitumor immunity and CAR-macrophage immunotherapy
Wang X, Wang X, Li H, Liu S, Lu Y, Chen H, Cai X, Su S, Li B, Liu R, Hu W, Zhu X, Zhang J, Ye Y, Li H. tRNA m1A modification orchestrates STING translation in macrophages to enhance antitumor immunity and CAR-macrophage immunotherapy. Cellular & Molecular Immunology 2026, 23: 261-272. PMID: 41535541, PMCID: PMC12949049, DOI: 10.1038/s41423-025-01383-7.Peer-Reviewed Original ResearchIntrathecal CRISPR-edited allogeneic IL-13Rα2 CAR T Cells for recurrent high-grade Glioma: preclinical characterization and phase I trial
Li X, Shang X, Liu J, Zhang Y, Jia X, Li H, Wang Y, Gao J, Ma X, Zhang X, Rong X, Gan W, Zhang Y, Chen J, Wang L, Bao Z, He L, Yan X, Liu Y, Shao J, Xiao Z, Wang Z, Zhu H, Wang Z, Wu Y, Huang Y. Intrathecal CRISPR-edited allogeneic IL-13Rα2 CAR T Cells for recurrent high-grade Glioma: preclinical characterization and phase I trial. Nature Communications 2026, 17: 1362. PMID: 41495049, PMCID: PMC12877024, DOI: 10.1038/s41467-025-68112-6.Peer-Reviewed Original ResearchAdultAgedAnimalsBrain NeoplasmsCell Line, TumorCRISPR-Cas SystemsFemaleGene EditingGlioblastomaGliomaGraft vs Host DiseaseHumansImmunotherapy, AdoptiveInterleukin-13 Receptor alpha2 SubunitKiller Cells, NaturalMaleMiceMiddle AgedNeoplasm Recurrence, LocalReceptors, Chimeric AntigenT-LymphocytesTreatment OutcometRNA m1A modification is essential for gut homeostasis and function of group 3 innate lymphoid cells
Li J, Tang Z, Chen Y, Cai X, Wu L, Wang G, Kan C, Li B, Su B, Li H, Chu C, Li H. tRNA m1A modification is essential for gut homeostasis and function of group 3 innate lymphoid cells. Cell Discovery 2026, 12: 1. PMID: 41484094, PMCID: PMC12764812, DOI: 10.1038/s41421-025-00850-9.Peer-Reviewed Original Research
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