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Gretchen Hermes, MD, PhD

Associate Professor of Psychiatry; Medical Director, APT Foundation; Chief Psychiatrist, Yale Stress Center; Addiction Psychiatry Fellowship Coordinator, APT Foundation

Contact Information

Gretchen Hermes, MD, PhD

Patient Care Locations

Lab Location

  • Brady Memorial Laboratory
    310 Cedar Street, Ste 416
    New Haven, CT 06510

Office Location

  • Doctors Building
    2 Church Street South, Fl 2nd, Ste 208, Rm 209
    New Haven, CT 06519

Mailing Address

  • Psychiatry

    2 Church St S

    New Haven, CT 06519

    United States



Gretchen Hermes completed her MD/PhD on pre-clinical stress-diathesis models of social neglect at the University of Chicago with Martha K. McClintock PhD, a pioneer in the field of social neuroscience. These developmental models of psychopathology (schizophrenia, depression) laid the foundation for her current research on co-morbid mental illness and addiction. Dr. Hermes entered the Yale Residency in the Neuroscience Research Training Program where she continued work with Ronald Duman PhD on preclinical models of social neglect and currently is engaged as a co-investigator at the Yale Stress Center working with Rajita Sinha, PhD, on research protocols related to effects of adrenergic receptor agonists on drug craving and withdrawal as well as large cohort studies on the long-ranging effects of early life trauma vs. acute stress. Dr. Hermes has ongoing collaborative research with the Section of Comparative Medicine and the Yale Depression Research Program on the role of mitochondrial proteins in facilitating synaptic neurotransmission, representing a potential paradigm shift toward a role for energy and biogenesis in mental illness.

While at the University of Chicago, Dr. Hermes completed post-doctoral work in infectious disease. This preclinical work on the memory and mood effects of ‘quiescent’ forms Toxoplasma gondii with Rima McLeod, MD, a world leading authority on Toxoplasmosis, paved the way for nearly a decade of service as the Behavioral Health Director and psychiatry attending at AIDS Project New Haven (APNH). While at APNH, through symposia, clinical rounds, and data collection, Dr. Hermes supported clinical efforts to address neurocognitive decline in members of the New Haven community living with HIV/AIDS.

Dr. Hermes established and co-teaches the Neurobiology of Addiction course for Psychiatry and Medicine Addiction fellows at Yale. She is the site director of the Addiction Psychiatry fellowship at the APT Foundation.

Prior to medical and research training, Dr. Hermes worked as a writer and multimedia producer at the Smithsonian Institution collaborating with Apple Computer, Lucas Film and Discovery Channel on the award winning interactive educational program on the discovery of DNA, Life Story, which Wired magazine identified as seminal in the development of multimedia. Dr. Hermes was a graduate student at Harvard Divinity School completing field work in northern Ethiopia on early syncretistic expressions of Christianity and Judaism in the Ethiopian Orthodox Church at Lalibela. In addition, Dr. Hermes has completed psychoanalytic training at the Western New England Institute for Psychoanalysis and maintains active interest in core psychoanalytic principles as they relate to addiction including trauma, attachment, and mourning; struggles with anxiety and embittered hope; the harshness of lost containers and lost thinking. She reflects often on ethical approaches to addiction treatment and on Dorothy Day’s theology of hospitality and human dignity.

Education & Training

  • Research Fellowship, Schizophrenia
    Yale University (2013)
  • Residency
    Yale University (2011)
  • MD
    University of Chicago Pritzker School of Medicine (2007)
  • Postdoctoral Fellowship, NIH, Interdisciplinary Program in Immunology
    University of Chicago (2005)
  • PhD
    University of Chicago (2003)
  • MA
    Harvard Divinity School (1997)

Honors & Recognition

AwardAwarding OrganizationDate
NARSAD Young Investigator GrantBrain and Behavior Research Foundation2015
Workshop on Schizophrenia and Related Disorders, Travel Award and StipendCold Spring Harbor Laboratory2012
Daniel X. and Mary Freedman Fellowship in Academic PsychiatryFreedman Foundation2011
APA-Pfizer M.D., Ph.D. Research Fellowship AwardAmerican Psychiatric Association2011
Power Day Award, Psychiatry, for a resident nominated by 3rd year medical class, who serves as a true role model for Yale medical students Yale School of Medicine2011
APA-Janssen Resident Psychiatric Research ScholarAmerican Psychiatric Association2010
Seymour Lustman Award for Outstanding Resident ResearchYale Department of Psychiatry2009
ACNP Travel AwardAmerican College of Neuropsychopharmacology2008

Professional Service

Female Opioid Research and Clinical Experts (FORCE)Member2017 - Present
California Breast Cancer Research Program; University of California, Office of the PresidentPeer Review: Grant submissions in response to an Animal Models Initiative to Investigate Concurrent Effects of Environmental Chemicals and Stress Factors on Mammary Cancer2016 - Present
Ad Hoc ReviewerBrain, Behavior, and Immunity; Frontiers: Schizophrenia, Associate Editor; Neuropharmacology; Neuroendocrinology; Neuroscience Letters; Psychoneuroimmunolgy; Psychiatry Research; Sage OPEN Publications; Schizophrenia Research; Schizophrenia Bulletin 2008 - Present

Departments & Organizations