Cassie Overstreet
Associate Research Scientist in PsychiatryAbout
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Associate Research Scientist in Psychiatry
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Research at a Glance
Yale Co-Authors
Frequent collaborators of Cassie Overstreet's published research.
Publications Timeline
A big-picture view of Cassie Overstreet's research output by year.
Joel Gelernter, MD
Daniel F. Levey, PhD
Renato Polimanti, PhD, MSc
Joseph D. Deak, PhD
Hang Zhou, PhD
Marco Galimberti
11Publications
768Citations
Publications
2026
Genomic Study of Resilience to Posttraumatic Stress Disorder in the Million Veteran Program
Overstreet C, Levey D, Adhikari K, Galimberti M, Pathak G, Pietrzak R, Zhou H, Løkhammer S, Polimanti R, Harrington K, Quaden R, Amstadter A, Gaziano J, Stein M, Gelernter J, Muralidhar S, Moser J, Deen J, Tsao P, Gaziano J, Hauser E, Kilbourne A, Matheny M, Oslin D, Voora D, Gaziano J, Tsao P, Brewer J, Brophy M, Cho K, Churby L, DuVall S, Pyarajan S, Ringer R, Selva L, Shayan S, Stephens B, Whitbourne S, Assimes T, Hung A, Kranzler H. Genomic Study of Resilience to Posttraumatic Stress Disorder in the Million Veteran Program. Biological Psychiatry 2026 PMID: 41763442, DOI: 10.1016/j.biopsych.2026.01.022.Peer-Reviewed Original ResearchCitationsAltmetric
2025
Differences and similarities between the genetic architecture of lifetime substance use across different substances
Bright U, Overstreet C, Levey D, Gelernter J. Differences and similarities between the genetic architecture of lifetime substance use across different substances. Psychological Medicine 2025, 55: e219. PMID: 40736093, PMCID: PMC12341034, DOI: 10.1017/s0033291725101293.Peer-Reviewed Original ResearchCitationsA contextual genomic perspective on physical activity and its relationship to health, well being and illness
Galimberti M, Levey D, Deak J, Adhikari K, Overstreet C, Gupta P, Nitin R, Zhou H, Lake N, Harrington K, Djousse L, Davis L, Gaziano J, Stein M, Gelernter J. A contextual genomic perspective on physical activity and its relationship to health, well being and illness. Nature Genetics 2025, 57: 1860-1871. PMID: 40691405, PMCID: PMC12339386, DOI: 10.1038/s41588-025-02260-9.Peer-Reviewed Original ResearchCitationsAltmetricShared genetic architecture of posttraumatic stress disorder with cardiovascular imaging, risk, and diagnoses
Shen J, Valentim W, Friligkou E, Overstreet C, Choi K, Koller D, O’Donnell C, Stein M, Gelernter J, Lv H, Sun L, Falcone G, Polimanti R, Pathak G. Shared genetic architecture of posttraumatic stress disorder with cardiovascular imaging, risk, and diagnoses. Nature Communications 2025, 16: 5631. PMID: 40595462, PMCID: PMC12217169, DOI: 10.1038/s41467-025-60487-w.Peer-Reviewed Original ResearchCitationsAltmetricThe genetic relationship between cannabis use disorder, cannabis use and psychiatric disorders
Galimberti M, Overstreet C, Gupta P, Beck S, Dao C, Deak J, Zhou H, Johnson E, Agrawal A, Stein M, Levey D, Gelernter J. The genetic relationship between cannabis use disorder, cannabis use and psychiatric disorders. Nature Mental Health 2025, 3: 700-708. DOI: 10.1038/s44220-025-00440-4.Peer-Reviewed Original ResearchCitationsAltmetricOptimism moderates the relationship between inflammatory polygenic risk and major depressive disorder in U.S. Military veterans
Fischer I, Overstreet C, Cabrera-Mendoza B, Qiu D, Krystal J, Polimanti R, Gelernter J, Pietrzak R. Optimism moderates the relationship between inflammatory polygenic risk and major depressive disorder in U.S. Military veterans. The World Journal Of Biological Psychiatry 2025, 26: 189-198. PMID: 40343713, DOI: 10.1080/15622975.2025.2498352.Peer-Reviewed Original ResearchCitationsAltmetricEpigenetic and genetic profiling of comorbidity patterns among substance dependence diagnoses
Pathak G, Pietrzak R, Lacobelle A, Overstreet C, Wendt F, Deak J, Friligkou E, Nunez Y, Montalvo-Ortiz J, Levey D, Kranzler H, Gelernter J, Polimanti R. Epigenetic and genetic profiling of comorbidity patterns among substance dependence diagnoses. Molecular Psychiatry 2025, 30: 4435-4443. PMID: 40247127, PMCID: PMC12343199, DOI: 10.1038/s41380-025-03031-y.Peer-Reviewed Original ResearchCitationsAltmetricPsychometric properties and socio-demographic correlates of the Connor-Davidson Resilience Scale in three large population-based cohorts including Danish and Icelandic adults
Didriksen M, Daníelsdottir H, Bjarnadóttir M, Overstreet C, Choi K, Christoffersen L, Mikkelsen C, Aspelund T, Hauksdóttir A, Thordardottir E, Jakobsdóttir J, Tómasson G, Erikstrup C, Aagaard B, Bruun M, Ullum H, Sørensen E, Fischer I, Pietrzak R, Gelernter J, Campbell-Sills L, Stein M, Werge T, Pedersen O, Valdimarsdóttir U, Ostrowski S, Schork A. Psychometric properties and socio-demographic correlates of the Connor-Davidson Resilience Scale in three large population-based cohorts including Danish and Icelandic adults. Journal Of Mood And Anxiety Disorders 2025, 10: 100112. PMID: 40657597, PMCID: PMC12244040, DOI: 10.1016/j.xjmad.2025.100112.Peer-Reviewed Original ResearchCitations
2024
Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program
Verma A, Huffman J, Rodriguez A, Conery M, Liu M, Ho Y, Kim Y, Heise D, Guare L, Panickan V, Garcon H, Linares F, Costa L, Goethert I, Tipton R, Honerlaw J, Davies L, Whitbourne S, Cohen J, Posner D, Sangar R, Murray M, Wang X, Dochtermann D, Devineni P, Shi Y, Nandi T, Assimes T, Brunette C, Carroll R, Clifford R, Duvall S, Gelernter J, Hung A, Iyengar S, Joseph J, Kember R, Kranzler H, Kripke C, Levey D, Luoh S, Merritt V, Overstreet C, Deak J, Grant S, Polimanti R, Roussos P, Shakt G, Sun Y, Tsao N, Venkatesh S, Voloudakis G, Justice A, Begoli E, Ramoni R, Tourassi G, Pyarajan S, Tsao P, O’Donnell C, Muralidhar S, Moser J, Casas J, Bick A, Zhou W, Cai T, Voight B, Cho K, Gaziano J, Madduri R, Damrauer S, Liao K. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science 2024, 385: eadj1182-eadj1182. PMID: 39024449, PMCID: PMC12857194, DOI: 10.1126/science.adj1182.Peer-Reviewed Original ResearchCitationsAltmetricDistinguishing vulnerability and resilience to posttraumatic stress disorder evaluating traumatic experiences, genetic risk and electronic health records
Løkhammer S, Koller D, Wendt F, Choi K, He J, Friligkou E, Overstreet C, Gelernter J, Le Hellard S, Polimanti R. Distinguishing vulnerability and resilience to posttraumatic stress disorder evaluating traumatic experiences, genetic risk and electronic health records. Psychiatry Research 2024, 337: 115950. PMID: 38744179, PMCID: PMC11156529, DOI: 10.1016/j.psychres.2024.115950.Peer-Reviewed Original ResearchCitationsAltmetric
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