Caitlin Davis, PhD
Assistant ProfessorCards
About
Research
Overview
Quantification of the physics and chemistry of biomolecule interactions inside cells is challenging due to the complex environment, fast timescales of motions, and difficulties in controlling reactions. The unifying theme of our research is the development of new quantitative spectroscopic imaging techniques to elucidate the relationship between function and dynamics of proteins and RNA inside living cells.
Our research lies at the intersection of traditional chemistry, physics, and biology disciplines, with an emphasis on quantitative physical characterization of biological systems. Our efforts combine elements of physical chemistry (thermodynamics, kinetics, spectroscopy), molecular biology (mutation, proteins, RNA), cell biology (live-cell microscopy, mammalian cell culture, zebrafish model), and theoretical chemistry (simulations and modeling).
News & Links
Media
- Motivated by diseases arising from the misregulation of proteins and RNA, our biophysical approach makes connections between molecular mechanism and cellular function through time-resolved spectral imaging at multiple scales, from in vitro to single cell to whole organism.