Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsAlfonso Galderisi, MD, PhD
he/him/his
Associate Professor AdjunctAbout
Research
Publications
2026
High-intensity interval training: safe and beneficial physical activity strategy in adolescents with type 1 diabetes.
Soto J, Rozas K, León A, Ponce N, Venegas R, Pelicand J, Paiva O, Galderisi A, Fox L, Gleisner A. High-intensity interval training: safe and beneficial physical activity strategy in adolescents with type 1 diabetes. Hormone Research In Paediatrics 2026, 1-20. PMID: 41843720, DOI: 10.1159/000551568.Peer-Reviewed Original ResearchHigh-intensity interval trainingPhysical activityAerobic capacityHome-based HIITDepressive symptomsEffects of high-intensity interval trainingPhysical activity strategiesIntensity interval trainingMaximal oxygen consumptionMental health benefitsMonths of trainingType 1 diabetesEvaluate metabolic effectsLean mass increaseCardiovascular risk factorsStrength endurancePhysical fitnessInterval trainingLack of motivationCardiovascular healthBlood glucoseSecondary outcomesBody compositionTanner stage IIIDaily insulin doseNeurobehavioral outcomes at 12 months in very preterm infants monitored with continuous glucose monitoring at birth compared with full-term infants
Lasagni C, Cusinato M, Guiducci S, Avagliano L, Tolettini B, Res G, Savio F, Trevisanuto D, Priante E, Baraldi E, Galderisi A, Brigadoi S, Di Giorgio E. Neurobehavioral outcomes at 12 months in very preterm infants monitored with continuous glucose monitoring at birth compared with full-term infants. Scientific Reports 2026, 16: 9489. PMID: 41702956, PMCID: PMC13005029, DOI: 10.1038/s41598-026-37286-4.Peer-Reviewed Original ResearchConceptsVPT infantsFT infantsFull-termContinuous glucose monitoringFull-term infantsLong-term outcomesPreterm infantsMonths CAVery pretermNeurodevelopmental outcomesNeurodevelopmental delayGlucose monitoringPostnatal weekFollow-upGlycaemic controlNeurobehavioral outcomesInfantsGlucose variabilityGlycaemic variabilityLab-based tasksGlucose levelsPretermEarly detectionCognitive disturbancesBirth
2025
Impact of severe hypoglycemia on cerebral hemodynamics in very preterm neonates
Perkins G, Guiducci S, Res G, Savio F, Trevisanuto D, Priante E, Galderisi A, Baraldi E, Brigadoi S. Impact of severe hypoglycemia on cerebral hemodynamics in very preterm neonates. Progress In Biomedical Optics And Imaging 2025, 13935: 139350c-139350c-3. DOI: 10.1117/12.3098359.Peer-Reviewed Original ResearchPROMETEUS: hybrid TD-NIRS and SCOS instrument for real-time monitoring of brain metabolism in preterm neonates: system architecture and characterization
Negretti F, Amendola C, Brigadoi S, Buttafava M, Cooper R, Man C, Durduran T, Faure F, Fornasier M, Galderisi A, Lacerenza M, Marchiori H, Scarpa A, Spinelli L, Torricelli A, Contini D. PROMETEUS: hybrid TD-NIRS and SCOS instrument for real-time monitoring of brain metabolism in preterm neonates: system architecture and characterization. Progress In Biomedical Optics And Imaging 2025, 13935: 139350j-139350j-3. DOI: 10.1117/12.3098366.Peer-Reviewed Original ResearchEndoCompass Project: Research Roadmap for Diabetes, Obesity, and Metabolism
Mathieu C, Meireles M, Pagotto U, Wabitsch M, Banerjee I, Bartolomé A, Battelino T, Beck J, Chiarelli F, De Leon D, Dovč K, Goch M, Galderisi A, Gevers E, Gillard P, Haliloglu B, Hoermann H, Mankovsky B, Mertens J, Mohnike K, Oram R, Pasquini T, Pearson E, Pieber T, Polovina S, Raskin J, Roeper M, Ruck L, Estebanez M, Tankova T, Thornton P, van Rossum E, Vukovic R, Worth C, Zachurzok A. EndoCompass Project: Research Roadmap for Diabetes, Obesity, and Metabolism. Hormone Research In Paediatrics 2025, 98: 60-90. PMID: 41296660, PMCID: PMC12698134, DOI: 10.1159/000549194.Peer-Reviewed Original ResearchConceptsBurden of metabolic disordersEuropean SocietyEuropean Society of EndocrinologyResearch prioritiesDual receptor agonistSociety of EndocrinologyEuropean Society of Paediatric EndocrinologyBehavioral interventionsImpact of endocrine disordersMicrobiome analysisType 1 diabetesDisease-modifying therapiesReceptor agonistsEnvironmental influencesObesity pathophysiologyPatient advocacy groupsMonogenic disordersEndocrine SocietyTreatment strategiesEndocrine disordersIncretin mimeticsResearch fundingPaediatric endocrinologyDisordersHormonal healthArtificial intelligence-driven clinical decision support systems to assist healthcare professionals and people with diabetes in Europe at the point of care: a Delphi-based consensus roadmap
Bajramagic M, Battelino T, Cos X, Cote M, Cui N, Forbes A, Galderisi A, Heinemann L, Hussain S, Imbert J, Holm Jönsson C, Joubert M, Lalić N, Phillip M, Schwarz P, Torbeyns B, Wake D, Zakrzewska K, Del Prato S. Artificial intelligence-driven clinical decision support systems to assist healthcare professionals and people with diabetes in Europe at the point of care: a Delphi-based consensus roadmap. Diabetologia 2025, 69: 259-273. PMID: 41247494, PMCID: PMC12779661, DOI: 10.1007/s00125-025-06601-5.Peer-Reviewed Original ResearchClinical decision support systemsDiabetes careHealthcare professionalsDecision support systemArtificial intelligencePrimary care healthcare professionalsCare healthcare professionalsBurden of diabetesNominal group techniqueSupport systemWorking GroupPoint of careImplementation of AI technologiesTreatment of peopleDiabetes servicesFace-to-faceAI-driven technologiesFace-to-face meetingsDiabetes forumClinical spaceCareAI technologyTreatment inertiaDelphi methodologyGroup techniqueBaseline Insulin Secretion Determines Response to Abatacept in Stage 1 Type 1 Diabetes.
Galderisi A, Carr A, Taylor P, Bonet J, Cuthbertson D, Sosenko J, Sims E, Evans-Molina C, Dalla Man C, Ismail H, Nathan B, Petrelli A, Senior P, Sherr J, Herold K, Russell W, Moran A, Dayan C. Baseline Insulin Secretion Determines Response to Abatacept in Stage 1 Type 1 Diabetes. Diabetes 2025, 75: 229-240. PMID: 41237315, PMCID: PMC12823341, DOI: 10.2337/db25-0801.Peer-Reviewed Original ResearchMonths of progression-free survivalResponse to abataceptProgression-free survivalB cell functionHazard of progressionDelay disease progressionBaseline insulin secretionOral minimal modelTreatment cessationB cellsDisease progressionLow secretorsAbataceptContinuous treatmentInsulin secretionBaselineSubgroups of respondentsTreatmentProgressionPlaceboEndoCompass project: research roadmap for diabetes, obesity, and metabolism
Mathieu C, Meireles M, Pagotto U, Wabitsch M, Banerjee I, Bartolomé A, Battelino T, Beck J, Chiarelli F, De Leon D, Dovč K, Ghoch M, Galderisi A, Gevers E, Gillard P, Haliloglu B, Hoermann H, Mankovsky B, Mertens J, Mohnike K, Oram R, Pasquini T, Pearson E, Pieber T, Polovina S, Raskin J, Roeper M, Ruck L, Estebanez M, Tankova T, Thornton P, van Rossum E, Vukovic R, Worth C, Zachurzok A. EndoCompass project: research roadmap for diabetes, obesity, and metabolism. European Journal Of Endocrinology 2025, 193: ii47-ii71. PMID: 41104472, DOI: 10.1093/ejendo/lvaf065.Peer-Reviewed Original ResearchConceptsBurden of metabolic disordersEuropean SocietyEuropean Society of EndocrinologyResearch prioritiesDual receptor agonistSociety of EndocrinologyEuropean Society of Paediatric EndocrinologyMicrobiome analysisImpact of endocrine disordersType 1 diabetesDisease-modifying therapiesBehavioral interventionsReceptor agonistsObesity pathophysiologyMonogenic disordersPatient advocacy groupsEndocrine SocietyEnvironmental influencesTreatment strategiesEndocrine disordersIncretin mimeticsResearch fundingPaediatric endocrinologyHormonal healthEvidence-based roadmapA Deep Clinical and Biochemical Characterization of a Patient With Combined Malonic and Methylmalonic Aciduria (CMAMMA)
Gragnaniello V, Galderisi A, Tucci S, Doimo M, Caterino M, Loro C, Cazzorla C, Ruoppolo M, Salviati L, Burlina A. A Deep Clinical and Biochemical Characterization of a Patient With Combined Malonic and Methylmalonic Aciduria (CMAMMA). 2025, 66: e70045. PMID: 41030468, PMCID: PMC12476969, DOI: 10.1002/jmd2.70045.Peer-Reviewed Original ResearchHyperinsulinemic hypoglycemiaPyruvate dehydrogenaseMalonyl-CoA synthetaseLipoic acid biosynthesisClinical presentationA-ketoglutarate dehydrogenaseRegulate insulin secretionInborn errorsMethylmalonic aciduriaUrinary organic acid analysisLipoic acid levelsMalonyl-CoAAcid biosynthesisBiochemical characterizationSevere neurological impairmentInborn errors of metabolismOrganic acid analysisA-ketoglutarateErrors of metabolismNeonatal periodAcid analysisCMAMMAClinical phenotypeMolecular testingMethylmalonic acidAutomated Oral Minimal Models for Rapid Estimation of Insulin Sensitivity and Beta-Cell Responsivity in Large-Scale Data Sets: A Validation Study.
Perazzolo S, Galderisi A, Carr A, Dayan C, Cobelli C. Automated Oral Minimal Models for Rapid Estimation of Insulin Sensitivity and Beta-Cell Responsivity in Large-Scale Data Sets: A Validation Study. Journal Of Diabetes Science And Technology 2025, 19322968251365274. PMID: 40899768, PMCID: PMC12408534, DOI: 10.1177/19322968251365274.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
News
News
- November 25, 2025
Alfonso Galderisi, MD, PhD: What to Know During Diabetes Awareness Month
- October 08, 2025Source: Science Press Releases
vTv Therapeutics Announces New Appointments to its Scientific Advisory Board
- February 28, 2024
Find Yale Pediatrics at the 2024 Pediatric Academic Societies (PAS) Meeting