2025
Factors associated with tuberculosis treatment initiation among bacteriologically negative individuals evaluated for tuberculosis: An individual patient data meta-analysis.
Kim S, Can M, Agizew T, Auld A, Balcells M, Bjerrum S, Dheda K, Dorman S, Esmail A, Fielding K, Garcia-Basteiro A, Hanrahan C, Kebede W, Kohli M, Luetkemeyer A, Mita C, Reeve B, Silva D, Sweeney S, Theron G, Trajman A, Vassall A, Warren J, Yotebieng M, Cohen T, Menzies N. Factors associated with tuberculosis treatment initiation among bacteriologically negative individuals evaluated for tuberculosis: An individual patient data meta-analysis. PLOS Medicine 2025, 22: e1004502. PMID: 39804959, PMCID: PMC11729971, DOI: 10.1371/journal.pmed.1004502.Peer-Reviewed Original ResearchConceptsIndividual Patient Data Meta-AnalysisPatient data meta-analysisTreatment initiationData Meta-AnalysisBacteriological test resultsTB treatmentFactors associated with treatment initiationMultiple factors influence decisionsAssociated with treatment initiationTuberculosis treatment initiationMeta-analysisNegative test resultsPositive test resultsFactors influence decisionsHIV infectionPulmonary tuberculosisSmear microscopyNight sweatsClinical examinationMale sexClinical criteriaHierarchical Bayesian logistic regressionCohort studySystematic reviewTreatment decisions
2022
Community-based referral for tuberculosis preventive therapy is effective for treatment completion
Shenoi S, Kyriakides T, Dokubo E, Guddera V, Vranken P, Desai M, Friedland G, Moll A. Community-based referral for tuberculosis preventive therapy is effective for treatment completion. PLOS Global Public Health 2022, 2: e0001269. PMID: 36962910, PMCID: PMC10021376, DOI: 10.1371/journal.pgph.0001269.Peer-Reviewed Original ResearchTreatment completionCommunity-based identificationPreventive therapyIndependent predictorsGovernment primary care clinicsMedian age 35 yearsCommunity-based referralsHigher treatment completionMedian CD4 countTB preventive therapyTB endemic regionsTuberculosis preventive therapyComparison groupPrimary care clinicsClinic-based careAge 35 yearsCBR groupTeam of nursesSix-month courseMedian CD4Oral isoniazidCD4 countHIV careNight sweatsCare clinics0590 Factors Associated with Sleep Health in Young Women After Breast Cancer Treatment
Hwang Y, Conley S, Jeon S, Redeker N, Sanft T, Knobf M. 0590 Factors Associated with Sleep Health in Young Women After Breast Cancer Treatment. Sleep 2022, 45: a259-a260. DOI: 10.1093/sleep/zsac079.587.Peer-Reviewed Original ResearchPittsburgh Sleep Quality IndexPoor sleep healthSleep healthBreast cancerPsychosocial dataGlobal Pittsburgh Sleep Quality IndexYoung womenCancer treatmentRoutine survivorship careSevere night sweatsSleep Quality IndexBreast cancer treatmentCross-sectional studyPrimary cancer treatmentSignificant clinical problemYears of ageQuality of lifeNon-Hispanic whitesWarrants further investigationEndocrine therapyGeneral Functioning subscaleNight sweatsSurvivorship careClinical factorsCancer survivorsA 43-Year-Old Woman With Fatigue, Pancytopenia, and Mediastinal Adenopathy
Zeba F, Marotti J, Feller-Kopman D. A 43-Year-Old Woman With Fatigue, Pancytopenia, and Mediastinal Adenopathy. CHEST Journal 2022, 161: e293-e297. PMID: 35526899, DOI: 10.1016/j.chest.2021.12.653.Peer-Reviewed Original ResearchConceptsFamily history of malignancyHistory of malignancyHeavy menstrual bleedingAdmitted with fatigueSignificant medical historyShortness of breathFamily historySmoking habitsJoint painNeck swellingMediastinal adenopathyMenstrual bleedingEnvironmental exposuresNight sweatsMedical historyWeight lossWomenCurrent presentFatigueSmokingAdenopathyPancytopeniaMediastinitisMalignancyMedication
2021
An 84-Year-Old Physician With Progressive Dyspnea and Bilateral Upper Lobe Opacities
Harris ZM, Antin-Ozerkis D. An 84-Year-Old Physician With Progressive Dyspnea and Bilateral Upper Lobe Opacities. CHEST Journal 2021, 159: e325-e329. PMID: 33965157, DOI: 10.1016/j.chest.2020.12.035.Peer-Reviewed Original ResearchConceptsProgressive exertional dyspneaNumbness/tinglingLong-term medicationProximal muscle weaknessParoxysmal atrial fibrillationLifelong nonsmokersNaproxen 250Progressive dyspneaDry coughExertional dyspneaNight sweatsPulmonary clinicLumbar radiculopathySinus congestionSpinal stenosisAtrial fibrillationMuscle weaknessHashimoto's thyroiditisRecent travelMedical historyOlder physiciansWeight lossDyspneaThyroiditisPhysicians
2020
Progressive Dyspnea and Hypoxemia With Diffuse Pulmonary Infiltrates in a Previously Healthy Woman
Mainardi AS, Siddon AJ, Bader AS, Hilbert J. Progressive Dyspnea and Hypoxemia With Diffuse Pulmonary Infiltrates in a Previously Healthy Woman. CHEST Journal 2020, 158: e327-e334. PMID: 33280778, DOI: 10.1016/j.chest.2020.07.009.Peer-Reviewed Case Reports and Technical NotesConceptsAdmission laboratory test resultsMonths of coughMild respiratory distressViolaceous maculesAcneiform rashProgressive dyspneaAxillary adenopathyNight sweatsHealthy womenNew feverRespiratory distressDiffuse pulmonaryPhysical examinationWBC countPlatelet levelsConjunctival edemaFurther managementOxygen saturationPulmonary cracklesLaboratory test resultsDyspneaRashWomenAdenopathyHypoxemiaDisseminated Burkitt lymphoma presenting as massive gastrointestinal bleed
Harne PS, Macklin J, Muniraj T. Disseminated Burkitt lymphoma presenting as massive gastrointestinal bleed. Baylor University Medical Center Proceedings 2020, 33: 433-435. PMID: 32675976, PMCID: PMC7340431, DOI: 10.1080/08998280.2020.1747835.Peer-Reviewed Original ResearchBurkitt's lymphomaAggressive non-Hodgkin lymphomaBurkitt's lymphoma presentingPersistent tooth painWeeks of fatigueMassive gastrointestinal bleedNon-Hodgkin lymphomaDoughnut-shaped massCentral umbilicationGastrointestinal bleedLymphoma PresentingMassive hematemesisNight sweatsTarry stoolTooth painGastric massTargeted biopsiesChemotherapy treatmentComplete resolutionLymphomaWeight lossRoot canalsHematemesisEsophagogastroduodenoscopyPain
2018
A rare case of visceral leishmaniasis in an immunocompetent traveler returning to the United States from Europe
Haque L, Villanueva M, Russo A, Yuan Y, Lee EJ, Topal J, Podoltsev N. A rare case of visceral leishmaniasis in an immunocompetent traveler returning to the United States from Europe. PLOS Neglected Tropical Diseases 2018, 12: e0006727. PMID: 30286207, PMCID: PMC6171829, DOI: 10.1371/journal.pntd.0006727.Peer-Reviewed Case Reports and Technical NotesConceptsVisceral leishmaniasisHealthy travelersRare caseEndemic areasEndemic visceral leishmaniasisSuccessful initial treatmentLiposomal amphotericin BBone marrow biopsyImmunocompetent adultsImmunocompetent travelersNight sweatsImmunocompetent individualsInitial treatmentMarrow biopsyRelapseAmphotericin BPreventive measuresLeishmaniasisTreatmentUnited StatesExtensive experiencePancytopeniaSplenomegalyBiopsyPatientsVasomotor symptom characteristics
Gray KE, Katon JG, LeBlanc ES, Woods NF, Bastian LA, Reiber GE, Weitlauf JC, Nelson KM, LaCroix AZ. Vasomotor symptom characteristics. Menopause The Journal Of The North American Menopause Society 2018, 25: 520-530. PMID: 29206771, PMCID: PMC5898980, DOI: 10.1097/gme.0000000000001033.Peer-Reviewed Original ResearchConceptsVasomotor symptomsDiabetes riskNight sweatsHazard ratioHot flashesWomen's Health Initiative participantsElevated diabetes riskConfidence intervalsProportional hazards modelIncident diabetesMetabolic riskPostmenopausal symptomsMenopause transitionMean durationSymptom characteristicsInitiative participantsSymptomsDiabetesRiskBehavior changeSeverityWomenDurationSweatAssociation1134 A morbidly obese type I diabetic teenager with sleep apnea, nocturnal eating, and Cushingoid features. Where to start?
Hawkins M, Williams C, Kryger M. 1134 A morbidly obese type I diabetic teenager with sleep apnea, nocturnal eating, and Cushingoid features. Where to start? Sleep 2018, 41: a419-a420. DOI: 10.1093/sleep/zsy063.1133.Peer-Reviewed Original ResearchObstructive sleep apneaMorning glucose levelsNocturnal eatingSleep apneaGlucose levelsDocumentation of hypoglycemiaInsulin resistance riskApnea-hypopnea indexSetting of diabetesBody mass indexDoses of insulinDiagnosis of diabetesAge 5 yearsAdverse health conditionsSalivary cortisol levelsType ICushingoid featuresPAP therapyCushingoid appearanceNight sweatsHypopnea indexHypothalamic dysfunctionPrompt treatmentCushing's diseaseNight-time behaviorA Young Man With Hemoptysis and Cavitary Lung Lesions
Brady VA, Zinchuk AV, Siegel MD, Possick JD. A Young Man With Hemoptysis and Cavitary Lung Lesions. CHEST Journal 2018, 153: e85-e88. PMID: 29626974, PMCID: PMC6026285, DOI: 10.1016/j.chest.2017.09.018.Peer-Reviewed Case Reports and Technical NotesConceptsBacillus Calmette-Guérin (BCG) vaccineCavitary lung lesionsPrior cigarette smokingCalmette-Guérin vaccineHistory of alcoholIntermittent hemoptysisNight sweatsCigarette smokingMusculoskeletal symptomsLung lesionsMild fatigueDrug useWeight lossHemoptysisYoung menMenDyspneaRashMedicationsSmokingFeverVaccineLesionsSymptomsMonths
2017
Longitudinal changes in menopausal symptoms comparing women randomized to low-dose oral conjugated estrogens or transdermal estradiol plus micronized progesterone versus placebo
Santoro N, Allshouse A, Neal-Perry G, Pal L, Lobo RA, Naftolin F, Black DM, Brinton EA, Budoff MJ, Cedars MI, Dowling NM, Dunn M, Gleason CE, Hodis HN, Isaac B, Magnani M, Manson JE, Miller VM, Taylor HS, Wharton W, Wolff E, Zepeda V, Harman SM. Longitudinal changes in menopausal symptoms comparing women randomized to low-dose oral conjugated estrogens or transdermal estradiol plus micronized progesterone versus placebo. Menopause The Journal Of The North American Menopause Society 2017, 24: 238-246. PMID: 27779568, PMCID: PMC5323337, DOI: 10.1097/gme.0000000000000756.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, CutaneousAdministration, OralAdultAutonomic Nervous System DiseasesDrug Therapy, CombinationEstradiolEstrogen Replacement TherapyEstrogensEstrogens, Conjugated (USP)FemaleHot FlashesHumansIrritable MoodLongitudinal StudiesMiddle AgedPostmenopauseProgesteroneProgestinsSleep Initiation and Maintenance DisordersTreatment OutcomeVasomotor SystemConceptsOral conjugated estrogensActive treatment armsBody mass indexTreatment armsRace/ethnicityMonths postrandomizationNight sweatsPostmenopausal womenHot flashesMass indexMenopausal symptomsConjugated estrogensEarly postmenopausal womenMenopausal hormone therapyFinal menstrual periodProportion of womenHormone regimensTransdermal estradiolTransdermal estrogenHormone therapyVasomotor symptomsSymptom reliefTreat analysisActive treatmentConventional dosesManagement Strategies for Sexual Health After Breast Cancer Diagnosis
Overton E, Hofstatter E, Miller D, Ratner E. Management Strategies for Sexual Health After Breast Cancer Diagnosis. 2017, 303-322. DOI: 10.1007/978-3-319-42451-4_19.Peer-Reviewed Original ResearchEstrogen receptor-positive breast cancerReceptor-positive breast cancerModerate hot flashesPast medical historyLast menstrual periodBreast cancer diagnosisEndocrine therapyNight sweatsVaginal drynessVaginal symptomsHot flashesPainful intercourseMedical historyMenstrual periodBreast cancerSexual healthFemale presentsCancer diagnosisMonthsSignificant benefitsGabapentinTamoxifenTherapySymptomsCancer
2016
A 17-Year-Old With Steroid-Resistant Nephrotic Syndrome
Band ME, Sheldon C, Brancato J, Parikh NS, D’Alessandri-Silva C. A 17-Year-Old With Steroid-Resistant Nephrotic Syndrome. 2016, 137: e20153205. PMID: 27244796, DOI: 10.1542/peds.2015-3205.Peer-Reviewed Original ResearchConceptsRenal biopsy resultsComplete blood countBiopsy resultsBlood countElevated serum uric acidNormal complete blood countSteroid-resistant nephrotic syndromeInitial laboratory workupShortness of breathOutside emergency departmentSerum uric acidLow back painMinimal change diseaseNormal echotextureImmunomodulator therapyNight sweatsRenal ultrasoundLaboratory workupCreatinine ratioRecurrent edemaBack painChange diseaseFacial swellingNephrotic syndromeEmergency department
2013
Self-reported menopausal symptoms, coronary artery calcification, and carotid intima-media thickness in recently menopausal women screened for the Kronos early estrogen prevention study (KEEPS)
Wolff EF, He Y, Black DM, Brinton EA, Budoff MJ, Cedars MI, Hodis HN, Lobo RA, Manson JE, Merriam GR, Miller VM, Naftolin F, Pal L, Santoro N, Zhang H, Harman SM, Taylor HS. Self-reported menopausal symptoms, coronary artery calcification, and carotid intima-media thickness in recently menopausal women screened for the Kronos early estrogen prevention study (KEEPS). Fertility And Sterility 2013, 99: 1385-1391. PMID: 23312232, PMCID: PMC3615128, DOI: 10.1016/j.fertnstert.2012.11.053.Peer-Reviewed Original ResearchMeSH KeywordsAdultCarotid Artery DiseasesCarotid Intima-Media ThicknessCohort StudiesCoronary Artery DiseaseDisease ProgressionDyspareuniaEstrogen Replacement TherapyEstrogensFemaleFollow-Up StudiesHot FlashesHumansLongitudinal StudiesMenopauseMiddle AgedMood DisordersPredictive Value of TestsSelf ReportConceptsKronos Early Estrogen Prevention StudyCarotid intima-media thicknessSelf-reported menopausal symptomsIntima-media thicknessMenopausal symptomsMenopausal womenSubclinical atherosclerosisVaginal drynessPrevention StudyEarly menopausal womenElevated CAC scorePredictors of CACCoronary artery calcificationMeasures of atherosclerosisSerum E2 levelsSymptoms of insomniaSelf-reported symptomsCross-sectional analysisLogistic regression modelsMenopause onsetArtery calcificationCAC scoreNight sweatsPersistent symptomsClimacteric symptoms
2010
Epidemiology of sleep-related complaints associated with sleep-disordered breathing in Bangkok, Thailand
Suwanprathes P, Won C, Komoltri C, Nana A, Kotchabhakdi N, Guilleminault C. Epidemiology of sleep-related complaints associated with sleep-disordered breathing in Bangkok, Thailand. Sleep Medicine 2010, 11: 1025-1030. PMID: 20643577, DOI: 10.1016/j.sleep.2010.04.007.Peer-Reviewed Original ResearchConceptsSleep-related complaintsNight sweatsDaytime sleepinessSleep-disordered breathingExcessive daytime sleepinessFirst epidemiologic studyNocturnal sleep timeHabitual snoringWaist circumferenceSleep disturbancesEndocrine diseasesHealth morbidityMale genderRisk factorsGreater BMIEpidemiologic studiesGreater prevalenceSleep timeSleep InventoryMultivariate analysisThai populationSleepComplaintsSignificant predictorsBMI
2008
Summary of aromatase inhibitor clinical trials in postmenopausal women with early breast cancer
Buzdar AU, Coombes RC, Goss PE, Winer EP. Summary of aromatase inhibitor clinical trials in postmenopausal women with early breast cancer. Cancer 2008, 112: 700-709. PMID: 18072256, DOI: 10.1002/cncr.23193.Peer-Reviewed Original ResearchConceptsAromatase inhibitorsEndocrine therapyAdjuvant therapyPostmenopausal womenClinical trialsBreast cancerEstrogen receptor-positive breast cancerEfficacy of AIsReceptor-positive breast cancerInitial adjuvant therapyEarly breast cancerEnd-organ effectsGold standard treatmentYears of treatmentAI therapyThrombolic eventsNight sweatsSkeletal eventsVaginal bleedingEndometrial cancerHot flashesBone resorptionEfficacy dataDisease outcomeOptimal duration
2007
Impact of chest CT on the clinical management of immunocompetent emergency department patients with chest radiographic findings of pneumonia
Banker P, Jain V, Haramati L. Impact of chest CT on the clinical management of immunocompetent emergency department patients with chest radiographic findings of pneumonia. Emergency Radiology 2007, 14: 383-388. PMID: 17701235, DOI: 10.1007/s10140-007-0659-0.Peer-Reviewed Original ResearchConceptsChest radiographic findingsEmergency department patientsChest CTCXR findingsDepartment patientsRadiographic findingsClinical managementSmall bowel obstructionSex-matched controlsRenal cell carcinomaT-testFindings of pneumoniaStudent's t-testAuscultation abnormalitiesBowel obstructionEndobronchial massNight sweatsChart reviewPulmonary embolismClinical presentationED patientsHypersensitivity pneumonitisCell carcinomaMean ageMultiple myeloma
2004
Quality of Life After Prophylactic Oophorectomy
Daly M. Quality of Life After Prophylactic Oophorectomy. 2004 DOI: 10.21236/ada428590.Peer-Reviewed Original ResearchQuality of lifeCancer risk reduction strategiesIncreased risk of ovarian cancerRisk of ovarian cancerRisk-reducing surgeryCompletion of data collectionOvarian cancerQuality of life implicationsRisk reduction strategiesSexual activity frequencyProphylactic oophorectomyProphylactic surgeryCoping strategiesStudy womenStudy outcomesSocial functioningIncreased riskSurgery groupData collectionNight sweatsShort-term differencesLife implicationsHot flashesClinical managementWomen
2003
Is This Woman Perimenopausal?
Bastian LA, Smith CM, Nanda K. Is This Woman Perimenopausal? JAMA 2003, 289: 895-902. PMID: 12588275, DOI: 10.1001/jama.289.7.895.Peer-Reviewed Original ResearchConceptsHigh follicle-stimulating hormone levelsGreatest positive likelihood ratioLower inhibin B levelsFollicle-stimulating hormone levelsMonths of amenorrheaPremenopausal control groupInhibin B levelsClinical examination findingsEnglish-language articlesPositive likelihood ratioNight sweatsVaginal drynessClimacteric symptomsPerimenopausal womenExamination findingsHot flashesMenstrual historyClinical examinationPerimenopausal statusHormone levelsMEDLINE searchWomen's agePerimenopauseControl groupSymptoms
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