2023
Craniopharyngioma presenting as a stroke mimic, a case report
Boivin Z, Ford C, Franco A. Craniopharyngioma presenting as a stroke mimic, a case report. JEM Reports 2023, 2: 100042. DOI: 10.1016/j.jemrpt.2023.100042.Peer-Reviewed Original ResearchVital sign abnormalitiesStroke mimicsInitial presentationEmergency physiciansStroke-like symptomsBrief hospital stayPatient's initial presentationRight hand weaknessTreatment of patientsMultitude of symptomsLaboratory resultsPatient's laboratory resultsSubsequent developmentHospital stayAdrenal crisisAdrenal insufficiencyHypothalamic dysfunctionHand weaknessPotential strokeInitial imagingClinical pictureIntracranial hemorrhageEmergency departmentEndocrine disordersCase report
2022
The Role of Surgical Approaches in the Multi-Modal Management of Adult Craniopharyngiomas
Hong CS, Omay SB. The Role of Surgical Approaches in the Multi-Modal Management of Adult Craniopharyngiomas. Current Oncology 2022, 29: 1408-1421. PMID: 35323318, PMCID: PMC8947636, DOI: 10.3390/curroncol29030118.Peer-Reviewed Original ResearchConceptsSurgical approachBenign primary brain tumorsAggressive surgical resectionAdjuvant radiation therapyOptimal surgical approachInvasive surgical approachPrimary brain tumorsSurgical treatment paradigmMulti-modal managementEloquent neural structuresEndoscopic endonasal approachBenign biologyClinical sequelaeHypothalamic dysfunctionOpen resectionSurgical resectionSignificant morbidityOptic apparatusSafe resectionTumor recurrenceTranscranial surgeryTreatment paradigmDisease entityHypothalamic functionLateral approach
2021
Dual activating FGFR1 mutations in pediatric pilomyxoid astrocytoma
Fomchenko EI, Reeves BC, Sullivan W, Marks AM, Huttner A, Kahle KT, Erson‐Omay E. Dual activating FGFR1 mutations in pediatric pilomyxoid astrocytoma. Molecular Genetics & Genomic Medicine 2021, 9: e1597. PMID: 33448156, PMCID: PMC8077124, DOI: 10.1002/mgg3.1597.Peer-Reviewed Original ResearchConceptsPilomyxoid astrocytomaPediatric patientsVariant allele frequencyHypothalamic/chiasmatic regionPathologic tissue diagnosisTreatment-related morbidityHigh recurrence ratePI3K/mTOR inhibitionYears of ageExome sequencing resultsSimilar time pointsWhole exome sequencing resultsHypothalamic dysfunctionClinical presentationSurgical managementRecurrence rateShorter survivalAggressive subtypeVision lossChiasmatic regionTissue diagnosisPatient tumorsRadiation therapyFGFR inhibitorsFGFR1 mutations
2019
Hypothalamic Responses to Cocaine and Food Cues in Individuals with Cocaine Dependence
Zhang S, Zhornitsky S, Le TM, Li CR. Hypothalamic Responses to Cocaine and Food Cues in Individuals with Cocaine Dependence. The International Journal Of Neuropsychopharmacology 2019, 22: 754-764. PMID: 31420667, PMCID: PMC6929672, DOI: 10.1093/ijnp/pyz044.Peer-Reviewed Original ResearchConceptsHealthy control participantsHypothalamic activationCocaine useCocaine-dependent participantsFood cuesCocaine addictionHypothalamic responseControl participantsCocaine Craving QuestionnaireRecent cocaine useFunctional magnetic resonance imagingMagnetic resonance imagingCue-related activationsInferior parietal cortexHypothalamic dysfunctionClinical variablesDopaminergic pathwaysTonic cravingFood intakeQuestionnaire scoresRodent studiesVisual cortexParietal cortexResonance imagingHypothalamus
2018
1134 A morbidly obese type I diabetic teenager with sleep apnea, nocturnal eating, and Cushingoid features. Where to start?
Hawkins M, Williams C, Kryger M. 1134 A morbidly obese type I diabetic teenager with sleep apnea, nocturnal eating, and Cushingoid features. Where to start? Sleep 2018, 41: a419-a420. DOI: 10.1093/sleep/zsy063.1133.Peer-Reviewed Original ResearchObstructive sleep apneaMorning glucose levelsNocturnal eatingSleep apneaGlucose levelsDocumentation of hypoglycemiaInsulin resistance riskApnea-hypopnea indexSetting of diabetesBody mass indexDoses of insulinDiagnosis of diabetesAge 5 yearsAdverse health conditionsSalivary cortisol levelsType ICushingoid featuresPAP therapyCushingoid appearanceNight sweatsHypopnea indexHypothalamic dysfunctionPrompt treatmentCushing's diseaseNight-time behavior
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