2025
5-Year Outcomes After Transcatheter or Surgical Aortic Valve Replacement in Low-Risk Patients With Aortic Stenosis
Forrest J, Yakubov S, Deeb G, Gada H, Mumtaz M, Ramlawi B, Bajwa T, Crouch J, Merhi W, Sang S, Kleiman N, Petrossian G, Robinson N, Sorajja P, Iskander A, Berthoumieu P, Tchétché D, Feindel C, Horlick E, Saito S, Oh J, Jung Y, Reardon M, Investigators L. 5-Year Outcomes After Transcatheter or Surgical Aortic Valve Replacement in Low-Risk Patients With Aortic Stenosis. Journal Of The American College Of Cardiology 2025, 85: 1523-1532. PMID: 40158212, DOI: 10.1016/j.jacc.2025.03.004.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementTranscatheter aortic valve replacement groupEvolut Low Risk trialEndpoint of all-cause mortalityAll-Cause MortalityNoninferior to surgeryLow-risk patientsAortic valve replacementSevere aortic stenosisSurgery groupKaplan-Meier estimatesLow-risk trialsAortic stenosisDisabling strokeValve replacementRisk trialsSurgical aortic valve replacementLost to follow-upRates of all-cause mortalityKansas City Cardiomyopathy Questionnaire summary scoreLow surgical riskQuestionnaire summary scoreQuality-of-life outcomesAttempted implantReintervention rate
2023
Early observations with an ERAS pathway for thyroid and parathyroid surgery: Moving the goalposts forward
Machado N, Mortlock R, Maduka R, Souza Cunha A, Dyer E, Long A, Canner J, Tanella A, Gibson C, Hyman J, Ogilvie J. Early observations with an ERAS pathway for thyroid and parathyroid surgery: Moving the goalposts forward. Surgery 2023, 175: 114-120. PMID: 37973430, PMCID: PMC10838521, DOI: 10.1016/j.surg.2023.06.052.Peer-Reviewed Original ResearchConceptsSurgery pathwayEnhanced recoverySurgery groupParathyroid surgerySignificant decreasePost-anesthesia care unit lengthAverage daily pain scoreSuperficial cervical plexus blockThyroid/parathyroid surgeryAverage daily morphineDaily pain scoresCervical plexus blockCases 1 yearStandard of careDaily morphineERAS pathwayPostoperative admissionPostoperative antiemeticsPostoperative morphineUnanticipated admissionPain scoresPerioperative outcomesPlexus blockProspective trialPatient groupSafety of Early Surgery in Hip Fracture Patients Taking Clopidogrel and/or Aspirin: A Systematic Review and Meta-Analysis
Lu W, Yon D, Lee S, Koyanagi A, Smith L, Shin J, Rahmati M, Xiao W, Li Y. Safety of Early Surgery in Hip Fracture Patients Taking Clopidogrel and/or Aspirin: A Systematic Review and Meta-Analysis. The Journal Of Arthroplasty 2023, 39: 1374-1383.e3. PMID: 37972664, DOI: 10.1016/j.arth.2023.11.012.Peer-Reviewed Original ResearchConceptsHip fracture patientsSafety of early surgeryEarly surgeryFracture patientsAspirin groupGroup of early surgeryShorter length of hospital stayOverall incidence of complicationsNon-antiplatelet groupLength of hospital stayDelayed surgery groupIntraoperative blood lossDiscontinuation of clopidogrelMeta-analysisIncidence of complicationsDual antiplatelet therapyFemoral neck fracturesHigh quality studiesDelayed surgerySurgery groupBlood lossPostoperative mortalityNo significant differenceAntiplatelet therapyWeb of Science3-Year Outcomes After Transcatheter or Surgical Aortic Valve Replacement in Low-Risk Patients With Aortic Stenosis
Forrest J, Deeb G, Yakubov S, Gada H, Mumtaz M, Ramlawi B, Bajwa T, Teirstein P, DeFrain M, Muppala M, Rutkin B, Chawla A, Jenson B, Chetcuti S, Stoler R, Poulin M, Khabbaz K, Levack M, Goel K, Tchétché D, Lam K, Tonino P, Ito S, Oh J, Huang J, Popma J, Kleiman N, Reardon M, Investigators L, Sorajja P, Byrne T, Kirshner M, Bajwa T, Crouch J, Coselli J, Silva G, Hebeler R, Stoler R, Islam A, Rousou A, Poulin M, Khabbaz K, Bladergroen M, Fail P, Netherland D, Lam K, Tonino W, Sudre A, Berthoumieu P, Tchétché D, Khalili H, Hughes G, Harrison J, De A, Tsau P, van Mieghem N, Larbalestier R, Yong G, Agarwal S, Martin W, Park S, Kleiman N, Reardon M, Mohammadi S, Rodes-Cabau J, Sparling J, Elkins C, Ganzel B, Matthews R, Starnes V, Ando K, Chevalier B, Farge A, DeFrain M, Muppala M, Combs W, Bagur R, Chu M, Fontana G, Dev V, Leya F, Tuchek J, Inglessis I, Jassar A, Piazza N, Lacappelle K, Steinberg D, Katz M, Wang J, Kozina J, Slachman F, Merritt R, Chawla A, Jensen B, Alvarez J, Gooley R, Smith J, Ibrahim R, Cartier R, Rovin J, Fujita T, Rutkin B, Yakubov S, Song H, Zahr F, Miyagawa S, Rajagopal V, Kauten J, Gada H, Mumtaz M, Bhindi R, Brady P, Batra S, Davis T, Iskander A, Heimansohn D, Hermiller J, Takamisawa I, Haldis T, Yamazaki S, Teirstein P, Tada N, Saito S, Merhi W, Leung S, Muller D, Heijmen R, Petrossian G, Robinson N, Knight P, Ling F, Radhakrishnan S, Fremes S, Lehr E, Gafoor S, Noel T, Walton A, Resar J, Adams D, Sharma S, Lilly S, Tadros P, Zorn G, Dauerman H, Ittleman F, Horlick E, Feindel C, Welt F, Sharma V, Markowitz A, Carroll J, Fullerton D, Griffith B, Gupta A, de Marchena E, Salerno T, Chetcuti S, Deeb G, Sultan I, Goel K, Pasupati S, Kon N, Zhao D, Ramlawi B, Forrest J. 3-Year Outcomes After Transcatheter or Surgical Aortic Valve Replacement in Low-Risk Patients With Aortic Stenosis. Journal Of The American College Of Cardiology 2023, 81: 1663-1674. PMID: 36882136, DOI: 10.1016/j.jacc.2023.02.017.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementAortic valve replacementLow-risk patientsCause mortalityPrimary endpointParavalvular regurgitationValve replacementEvolut Low Risk trialLow surgical risk patientsSurgical aortic valve replacementGreater paravalvular regurgitationLow-risk trialsData comparing outcomesLow-risk studiesSupra-annular valveEchocardiographic outcomesSecondary endpointsSurgery groupTAVR patientsRisk patientsSurgery patientsAortic stenosisPacemaker placementTreatment armsMean age
2022
Uterine administration of C-X-C motif chemokine ligand 12 increases the pregnancy rates in mice with induced endometriosis
Rosa-E-Silva ACJS, Mamillapalli R, Rosa-E-Silva JC, Ucar A, Schwartz J, Taylor HS. Uterine administration of C-X-C motif chemokine ligand 12 increases the pregnancy rates in mice with induced endometriosis. F&S Science 2022, 4: 65-73. PMID: 36252793, DOI: 10.1016/j.xfss.2022.10.003.Peer-Reviewed Original ResearchConceptsC motif chemokine ligand 12Endometriosis groupPregnancy rateChemokine ligand 12Alpha v beta 3 integrinUterine injectionBeta 3 integrinBMDC recruitmentProgesterone receptorMouse modelBone marrow-derived cell recruitmentHigher cumulative pregnancy rateLigand 12Therapeutic agentsEndometrial receptivity defectsCumulative pregnancy rateEndometrial receptivity markersSham surgery groupBone marrow transplantationLower pregnancy ratesAcademic medical centerPotential therapeutic agentReceptivity markersSurgery groupInduced endometriosis2-Year Outcomes After Transcatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients
Forrest JK, Deeb GM, Yakubov SJ, Rovin JD, Mumtaz M, Gada H, O'Hair D, Bajwa T, Sorajja P, Heiser JC, Merhi W, Mangi A, Spriggs DJ, Kleiman NS, Chetcuti SJ, Teirstein PS, Zorn GL, Tadros P, Tchétché D, Resar JR, Walton A, Gleason TG, Ramlawi B, Iskander A, Caputo R, Oh JK, Huang J, Reardon MJ. 2-Year Outcomes After Transcatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients. Journal Of The American College Of Cardiology 2022, 79: 882-896. PMID: 35241222, DOI: 10.1016/j.jacc.2021.11.062.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementEvolut Low Risk trialLow-risk trialsAortic valve replacementPrimary endpointRisk trialsCause mortalityValve replacementTranscatheter Versus Surgical Aortic Valve ReplacementLow surgical risk patientsSurgical aortic valve replacementIndependent clinical events committeeEchocardiographic core laboratoryKaplan-Meier ratesSevere aortic stenosisClinical events committeeLow-risk patientsCause mortality ratesSelf-expanding valvesDisabling strokeEchocardiographic outcomesSurgical AVRTAVR groupSurgery groupAdverse events
2021
A systematic review and meta-analysis on endovascular treatment as an attractive alternative for acute superior mesenteric venous thrombosis
Wang L, Wang E, Liu F, Zhang W, Shu X, Guo D, Fu W. A systematic review and meta-analysis on endovascular treatment as an attractive alternative for acute superior mesenteric venous thrombosis. Vascular 2021, 30: 331-340. PMID: 33947286, DOI: 10.1177/1708538121991270.Peer-Reviewed Original ResearchConceptsSuperior mesenteric venous thrombosisMesenteric venous thrombosisEndovascular treatmentSurgery groupConservative treatmentVenous thrombosisPatients treated with endovascular therapyAcute superior mesenteric venous thrombosisOne-year survival rateConservative treatment groupTreatment groupsSafety of therapyMeta-analysisStatistical significanceOccurrence of complicationsSystematic reviewChanges of symptomsEndovascular approachSurgical treatmentLack of statistical significanceEndovascular therapyTreatment optionsClinical optionOdds ratioSurvival rate
2020
Leadless pacemaker implant in patients with a history of open heart surgery: experience with the Micra transcatheter pacemaker
Garweg C, Iacopino S, El-Chami M, Veltmann C, Clementy N, Grubman E, Johansen J, Knops R, Schalij M, Piccini J, Soejima K, Stromberg K, Fagan D, Roberts P. Leadless pacemaker implant in patients with a history of open heart surgery: experience with the Micra transcatheter pacemaker. European Heart Journal 2020, 41: ehaa946.0773. DOI: 10.1093/ehjci/ehaa946.0773.Peer-Reviewed Original ResearchOpen heart surgeryMicra transcatheter pacemakerHeart surgeryTranscatheter pacemakerMajor complicationsSurgery groupValve surgeryCardiac surgeryCardiac perforationTransvenous pacingOpen-heart surgery groupLong-term safety profileLeadless pacemakerCommon cardiac surgeryAortic valve surgeryCardiac surgery patientsMajor complication rateMitral valve surgeryCoronary artery diseaseMedian procedure timeProcedure-related infectionsPost-Approval RegistryDevice-related infectionsOral anticoagulantsComplication ratePediatric thyroidectomies: A surgical subspecialty comparison
Savoca E, Torabi SJ, Kasle D, Mets E, Hajek M, Waldman EH. Pediatric thyroidectomies: A surgical subspecialty comparison. International Journal Of Pediatric Otorhinolaryngology 2020, 132: 109945. PMID: 32070842, DOI: 10.1016/j.ijporl.2020.109945.Peer-Reviewed Original ResearchConceptsPediatric general surgeryShorter operative timePediatric general surgeonsMedical adverse eventsAdverse eventsGeneral surgeryOperative timeGeneral surgeonsNational Surgical Quality Improvement Program-Pediatric dataSurgical complication rateSurgical adverse eventsSub-group analysisGeneral surgery groupComplication differencesOtolaryngology groupPediatric thyroidectomyPerioperative courseSurgery groupComplication ratePatient characteristicsPediatric patientsPediatric populationAdverse outcomesSafe procedureUnivariate analysisBurden of emergency pediatric surgical procedures on surgical capacity in Uganda: a new metric for health system performance
Grabski D, Kakembo N, Situma M, Cheung M, Shikanda A, Okello I, Kisa P, Muzira A, Sekabira J, Ozgediz D. Burden of emergency pediatric surgical procedures on surgical capacity in Uganda: a new metric for health system performance. Surgery 2020, 167: 668-674. PMID: 31973913, DOI: 10.1016/j.surg.2019.12.002.Peer-Reviewed Original ResearchMeSH KeywordsBenchmarkingChild, PreschoolDatabases, FactualDigestive System AbnormalitiesEmergency Service, HospitalEmergency TreatmentFemaleHealth ResourcesHernia, InguinalHospital MortalityHumansInfantInfant, NewbornMaleProspective StudiesQuality Indicators, Health CareSurgical Procedures, OperativeUgandaConceptsMiddle-income countriesSurgical capacitySurgical acuityReferral hospitalElective casesInguinal herniaSurgical diseaseSurgical proceduresCongenital malformationsMulago National Referral HospitalMbarara Regional Referral HospitalPediatric surgical admissionsRatio of emergencyHealth metricsNational Referral HospitalRegional Referral HospitalPediatric surgical patientsPediatric surgical proceduresPediatric surgical capacityElective surgical casesTime of repairHealth system performanceSurgery groupSurgical admissionsDefinitive repair
2019
Head and Neck Reconstructive Surgery: Characterization of the One-Team and Two-Team Approaches
Torabi SJ, Chouairi F, Dinis J, Alperovich M. Head and Neck Reconstructive Surgery: Characterization of the One-Team and Two-Team Approaches. Journal Of Oral And Maxillofacial Surgery 2019, 78: 295-304. PMID: 31622570, DOI: 10.1016/j.joms.2019.09.011.Peer-Reviewed Original ResearchConceptsLonger operative timeMicrovascular free flapsOperative timeReconstructive surgeryFree flapNational Surgical Quality Improvement ProgramPropensity scoreSurgical Quality Improvement ProgramOperating roomHigher American SocietyIncidence of complicationsRate of complicationsNeck reconstructive surgeryLength of stayComplicated reconstructive proceduresQuality Improvement ProgramConcurrent headNeck OncosurgeryAnesthesiologists classificationPostoperative staySurgery groupComplication rateReconstructive headRetrospective studyNeck procedures
2017
Reoperation for growth hormone-secreting pituitary adenomas: report on an endonasal endoscopic series with a systematic review and meta-analysis of the literature.
Almeida JP, Ruiz-Treviño AS, Liang B, Omay SB, Shetty SR, Chen YN, Anand VK, Grover K, Christos P, Schwartz TH. Reoperation for growth hormone-secreting pituitary adenomas: report on an endonasal endoscopic series with a systematic review and meta-analysis of the literature. Journal Of Neurosurgery 2017, 129: 404-416. PMID: 28862548, DOI: 10.3171/2017.2.jns162673.Peer-Reviewed Original ResearchConceptsExtended endonasal endoscopic approachFirst-time surgeryCavernous sinus invasionPreoperative GH levelsSinus invasionSurgery groupControl rateDisease controlSystematic reviewReoperation groupTumor sizeGH levelsGrowth hormone-secreting pituitary adenomaHormone-secreting pituitary adenomasTransient diabetes insipidusDisease control rateFirst-line therapyResults of reoperationTime of surgerySmaller tumor sizeNegative prognostic indicatorSimilar control ratesLow control rateEndonasal endoscopic approachFirst-time operationsEarly Surgical Intervention for Acute Ulcerative Colitis Is Associated with Improved Postoperative Outcomes
Leeds IL, Truta B, Parian AM, Chen SY, Efron JE, Gearhart SL, Safar B, Fang SH. Early Surgical Intervention for Acute Ulcerative Colitis Is Associated with Improved Postoperative Outcomes. Journal Of Gastrointestinal Surgery 2017, 21: 1675-1682. PMID: 28819916, PMCID: PMC6201293, DOI: 10.1007/s11605-017-3538-3.Peer-Reviewed Original ResearchConceptsAcute ulcerative colitisEarly surgical interventionUlcerative colitisLength of staySurgical interventionSurgery groupTotal colectomyHospitalization costsEarly operationMedian total hospitalization costModern immunotherapy eraRefractory ulcerative colitisHours of admissionImmediate surgical interventionUlcerative colitis patientsTotal hospitalization costsFurther prospective studiesNational Inpatient SampleImmunotherapy eraColitis patientsHospital outcomesPostoperative complicationsPostoperative outcomesUrgent surgeryComorbid patients
2016
Umbilical hernias: the cost of waiting
Strosberg DS, Pittman M, Mikami D. Umbilical hernias: the cost of waiting. Surgical Endoscopy 2016, 31: 901-906. PMID: 27334965, DOI: 10.1007/s00464-016-5052-1.Peer-Reviewed Original ResearchConceptsHealth care utilizationSurgery groupNS groupUmbilical hernia patientsEarly operative interventionNon-operative managementBackgroundUmbilical herniaComorbidity indexIndex dateOperative interventionLaparoscopic repairAdjusted analysisHernia patientsSubgroup analysisUmbilical herniaWork absenteeismHealth databasesSurgeryHealth plansPatientsProcedure costsHealth careHerniaDaysMonthsTwo-Year Outcomes from a Randomized Controlled Trial of Minimally Invasive Sacroiliac Joint Fusion vs. Non-Surgical Management for Sacroiliac Joint Dysfunction.
Polly DW, Swofford J, Whang PG, Frank CJ, Glaser JA, Limoni RP, Cher DJ, Wine KD, Sembrano JN. Two-Year Outcomes from a Randomized Controlled Trial of Minimally Invasive Sacroiliac Joint Fusion vs. Non-Surgical Management for Sacroiliac Joint Dysfunction. The International Journal Of Spine Surgery 2016, 10: 28. PMID: 27652199, PMCID: PMC5027818, DOI: 10.14444/3028.Peer-Reviewed Original ResearchSubstantial clinical benefitNon-surgical treatmentSacroiliac joint dysfunctionTriangular titanium implantsClinical improvementMonth 24Clinical benefitSIJ painNSM groupSIJ dysfunctionJoint dysfunctionChronic low back painInvasive Sacroiliac Joint FusionChronic SIJ dysfunctionUnderwent revision surgeryNon-surgical managementTwo-Year OutcomesSacroiliac joint fusionLow back painProportion of subjectsQuality of lifeODI scoresSIJ fusionPain scoresSurgery group
2015
A Strategy for the Successful Management of Dermatofibrosarcoma Protuberans
Goldberg C, Hoang D, McRae M, Chung C, Leffell DJ, Narayan D. A Strategy for the Successful Management of Dermatofibrosarcoma Protuberans. Annals Of Plastic Surgery 2015, 74: 80-84. PMID: 23788146, DOI: 10.1097/sap.0b013e3182898692.Peer-Reviewed Original ResearchConceptsSurgical excisionPositive marginsDermatofibrosarcoma protuberansMohs surgeryNational Comprehensive Cancer Network guidelinesDisease recurrence/persistenceMargin sizeClear histological marginsComplications of reconstructionInitial surgical resectionRecurrence/persistenceTraditional surgical excisionSoft tissue sarcomasMethod of treatmentExcision patientsHistological marginsSurgery groupSubclinical involvementSurgical resectionMargin statusDistant metastasisNetwork guidelinesTissue sarcomasClinical variablesTumor resection
2014
Temporal Trends for Secondary Prevention Measures Among Patients Hospitalized with Coronary Artery Disease
Kumbhani D, Fonarow G, Cannon C, Hernandez A, Peterson E, Peacock W, Laskey W, Deedwania P, Grau-Sepulveda M, Schwamm L, Bhatt D, Committee and Investigators G. Temporal Trends for Secondary Prevention Measures Among Patients Hospitalized with Coronary Artery Disease. The American Journal Of Medicine 2014, 128: 426.e1-426.e9. PMID: 25433302, DOI: 10.1016/j.amjmed.2014.11.013.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAdultAgedAngiotensin Receptor AntagonistsAngiotensin-Converting Enzyme InhibitorsAspirinCardiovascular AgentsCoronary Artery BypassCoronary Artery DiseaseDirective CounselingFemaleGuideline AdherenceHumansHypolipidemic AgentsInpatientsMaleMiddle AgedPatient DischargePercutaneous Coronary InterventionPractice Guidelines as TopicRegistriesSecondary PreventionSmoking CessationUnited StatesConceptsCoronary artery bypass graft surgeryArtery bypass graft surgeryCoronary artery diseaseBypass graft surgerySecondary prevention measuresPercutaneous coronary intervention groupArtery diseaseGraft surgeryIntervention groupOverall adherenceGuidelines-Coronary Artery Disease registryPrevention measuresContemporary temporal trendsTime pointsPercutaneous coronary interventionPercutaneous coronary revascularizationEligible patientsCoronary revascularizationMultivariable adjustmentSurgery groupCoronary interventionRevascularization strategyCare measuresHospital adherenceTreatment groupsComparative Patient-Centered Outcomes (Health State and Adverse Sexual Symptoms) Between Adjuvant Brachytherapy Versus No Adjuvant Brachytherapy in Early Stage Endometrial Cancer
Damast S, Alektiar K, Eaton A, Gerber NK, Goldfarb S, Patil S, Jia R, Leitao M, Carter J, Basch E. Comparative Patient-Centered Outcomes (Health State and Adverse Sexual Symptoms) Between Adjuvant Brachytherapy Versus No Adjuvant Brachytherapy in Early Stage Endometrial Cancer. Annals Of Surgical Oncology 2014, 21: 2740-2754. PMID: 24619493, DOI: 10.1245/s10434-014-3562-4.Peer-Reviewed Original ResearchConceptsFemale Sexual Function IndexPoor health statesSexual functioningEndometrial cancerSexual functionEarly-stage endometrial cancerHealth statesStage I endometrial cancerBaseline sexual activityStage endometrial cancerEndometrial cancer survivorsSexual Function IndexSignificant risk factorsSurgery groupUnderwent surgeryEQ5D scoresFSFI scoreSurgery typeAdjuvant brachytherapyCancer survivorsMore frequent useRisk factorsFunction IndexSexual dysfunctionMultivariable regression
2012
Mental and physical impact of body contouring procedures on post-bariatric surgery patients.
Singh D, Zahiri HR, Janes LE, Sabino J, Matthews JA, Bell RL, Thomson JG. Mental and physical impact of body contouring procedures on post-bariatric surgery patients. Eplasty 2012, 12: e47. PMID: 22993645, PMCID: PMC3443403.Peer-Reviewed Original ResearchPost-bariatric surgery patientsShort Form Health SurveyQuality of lifeForm Health SurveySurgery patientsExcessive skinHealth SurveyControl groupPost-bariatric surgery populationWeight lossPlastic surgeryMassive weight lossCross-sectional studySignificant lower scoresBariatric surgeryObese patientsSurgery groupSurgery populationObese groupRole EmotionalSurgery showFunctional impairmentMental componentPatientsSurgeryChemoradiotherapy plus surgery versus surgery alone for resectable esophageal cancer: A systematic review of randomized control trials.
Njei B, Appiah J, Ditah I, Birk J. Chemoradiotherapy plus surgery versus surgery alone for resectable esophageal cancer: A systematic review of randomized control trials. Journal Of Clinical Oncology 2012, 30: 94-94. DOI: 10.1200/jco.2012.30.4_suppl.94.Peer-Reviewed Original ResearchConcurrent radiotherapyEsophageal cancerAdverse eventsProlonged survivalTreatment of esophageal cancerIncidence of adverse eventsResectable esophageal cancerSurgery only groupSub-group of patientsReview of randomized controlled trialsSystematic review of randomized controlled trialsLong-term survivalRandomized Controlled TrialsNeoadjuvant chemotherapyPlus surgeryStatistically significant increaseSurgery groupCombination therapySurvival benefitHistological typeGrade 3EC patientsSubgroup analysisTreatment strategiesCancer meetings
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