2025
Risk Factors in Patients Who Had Prior Renal or Liver Transplant Undergoing Primary Total Hip Arthroplasty
Gill V, Boddu S, Mansour E, Abu Jawdeh B, Khan M, McGary A, Clarke H, Spangehl M, Abdel M, Ledford C, Bingham J. Risk Factors in Patients Who Had Prior Renal or Liver Transplant Undergoing Primary Total Hip Arthroplasty. Journal Of Clinical Medicine 2025, 14: 3486. PMID: 40429481, PMCID: PMC12111864, DOI: 10.3390/jcm14103486.Peer-Reviewed Original ResearchAmerican Society of Anesthesiologists classSolid organ transplantationAmerican Society of Anesthesiologists class 4Associated with high mortalitySurgical complicationsAcute medical complicationsRenal transplantationLiver transplantationMedical complicationsOlder agePeri-operative risk profileOrgan transplantationHistory of solid organ transplantationMedian follow-up periodRisk factorsLikelihood of surgical complicationsTotal hip arthroplastyKaplan-Meier survival analysisRate of reoperationHigher mortalityAssociated with higher riskProportion of patientsFollow-up periodEstimate median survivalLow surgical complicationsPerioperative Point‐of‐Care Ultrasound Utilization in Abdominal Organ Transplantation. Part I: Preoperative and Intraoperative Care
Grell R, Paul J, Gupta K, Chawla N, Deshpande R, De Marchi L, Huang J. Perioperative Point‐of‐Care Ultrasound Utilization in Abdominal Organ Transplantation. Part I: Preoperative and Intraoperative Care. Clinical Transplantation 2025, 39: e70153. PMID: 40245256, PMCID: PMC12005607, DOI: 10.1111/ctr.70153.Peer-Reviewed Original ResearchConceptsAbdominal organ transplantationOrgan transplantationPoint-of-care ultrasoundTransplant anesthesiaIntensive care settingEvidenced-based recommendationsTransesophageal echocardiographyImprove patient outcomesAbdominal organ transplant patientsPoint-of-care ultrasound utilizationVenous congestionFluid managementAdvancement of Transplant AnesthesiaPatient outcomesUltrasound utilizationPOCUSUtilization of point-of-care ultrasoundTransplantationCritical careAnesthesiaMechanisms and strategies for organ recovery
Andrijevic D, Spajic A, Hameed I, Sheth K, Parnia S, Griesemer A, Montgomery R, Sestan N. Mechanisms and strategies for organ recovery. Nature Reviews Bioengineering 2025, 1-16. DOI: 10.1038/s44222-025-00293-7.Peer-Reviewed Original ResearchMechanisms of cellular injuryPerfusion systemHeart-lung machineSecondary cellular damageDecreased ATP productionIntracellular acidosisOrgan transplantationViability of mammalian cellsCirculating perfusateOxygen deliveryBlood supplyCellular injuryBlood flowInjured tissuePerfusionRestore circulationPharmacological compoundsIn vitroCell deathCellular demiseMammalian cellsATP productionResuscitation medicineOrgan recoveryBiological mechanisms
2024
The respiratory syncytial virus vaccines are here: Implications for solid organ transplantation
Trubin P, Azar M, Kotton C. The respiratory syncytial virus vaccines are here: Implications for solid organ transplantation. American Journal Of Transplantation 2024, 24: 897-904. PMID: 38341028, DOI: 10.1016/j.ajt.2024.02.003.Peer-Reviewed Original ResearchRespiratory syncytial virusSolid organ transplantationLower respiratory tract diseaseHigh risk of infectious complicationsBurden of RSV diseaseOrgan transplantationRisk of infectious complicationsRespiratory syncytial virus vaccineRespiratory tract diseaseCenters for Disease Control and Prevention's Advisory CommitteeOrgan transplant recipientsSolid organ recipientsPoor clinical outcomesFood and Drug AdministrationRSV F glycoproteinRespiratory virus vaccinesRSV diseaseInfectious complicationsTransplant recipientsClinical outcomesSyncytial virusClinical decision-makingImmunocompromised individualsOrgan recipientsImmunization PracticesEuropean Society for Organ Transplantation (ESOT) Consensus Statement on Outcome Measures in Liver Transplantation According to Value-Based Health Care
Carbone M, Neuberger J, Rowe I, Polak W, Forsberg A, Fondevila C, Mantovani L, Nardi A, Colli A, Rockell K, Schick L, Cristoferi L, Oniscu G, Strazzabosco M, Cillo U. European Society for Organ Transplantation (ESOT) Consensus Statement on Outcome Measures in Liver Transplantation According to Value-Based Health Care. Transplant International 2024, 36: 12190. PMID: 38332850, PMCID: PMC10850237, DOI: 10.3389/ti.2023.12190.Peer-Reviewed Original ResearchConceptsValue-based health careOutcome measuresEuropean Society of Organ TransplantationLiver transplantationDevelopment of outcome measuresConsensus statementOrgan transplantationValue-basedPatient-focusedAdvanced liver diseaseHealth careMultidisciplinary teamLiver diseaseTransplantationLife-savingEuropean Society for Organ TransplantationPatients
2023
Circulating T cell specific extracellular vesicle profiles in cardiac allograft acute cellular rejection
Korutla L, Hoffman J, Rostami S, Hu R, Korutla V, Markmann C, Mullan C, Sotolongo A, Habertheuer A, Romano C, Acker M, Sen S, Agarwal D, Jayaraman A, Li B, Davis M, Naji A, Vallabhajosyula P. Circulating T cell specific extracellular vesicle profiles in cardiac allograft acute cellular rejection. American Journal Of Transplantation 2023, 24: 419-435. PMID: 38295008, DOI: 10.1016/j.ajt.2023.10.021.Peer-Reviewed Original ResearchAcute cellular rejectionAllogeneic transplant recipientsTransplant recipientsCellular rejectionHeart transplantationAlloreactive T cell activationEarly acute cellular rejectionT-cell receptor sequencingSyngeneic transplant recipientsCell receptor sequencingClinical heart transplantationT cell clonesNovel candidate biomarkersT cell activationQuantitative RT-PCRRecipient circulationOrgan transplantationT cellsVesicle profilesNoninvasive biomarkersCandidate biomarkersCell activationRegulatory markersDonor cardiomyocytesTransplantationHedgehog costimulation during ischemia-reperfusion injury potentiates cytokine and homing responses of CD4+ T cells
Wang S, Song G, Barkestani M, Tobiasova Z, Wang Q, Jiang Q, Lopez R, Adelekan-Kamara Y, Fan M, Pober J, Tellides G, Jane-wit D. Hedgehog costimulation during ischemia-reperfusion injury potentiates cytokine and homing responses of CD4+ T cells. Frontiers In Immunology 2023, 14: 1248027. PMID: 37915586, PMCID: PMC10616247, DOI: 10.3389/fimmu.2023.1248027.Peer-Reviewed Original ResearchConceptsIschemia-reperfusion injuryHuman skin xenograftsSkin xenograftsT cellsPolyfunctional cytokine responsesSolid organ transplantationT cell subsetsResponse of CD4Expression of ICOST cell populationsHumanized mouse modelPeripheral helper cellsAllograft lossIL-21PD-1Reperfusion injuryCytokine responsesVascular inflammationPolyclonal expansionHelper cellsOrgan transplantationMouse modelClinical problemCostimulatory signalsDistinct subsetsRapid antimicrobial resistance detection methods for bloodstream infection in solid organ transplantation: Proposed clinical guidance, unmet needs, and future directions
Turbett S, Banach D, Bard J, Gandhi R, Letourneau A, Azar M. Rapid antimicrobial resistance detection methods for bloodstream infection in solid organ transplantation: Proposed clinical guidance, unmet needs, and future directions. Transplant Infectious Disease 2023, 25: e14113. PMID: 37594214, DOI: 10.1111/tid.14113.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsUnmet needSolid organ transplant recipientsOrgan transplant recipientsSolid organ transplantationTransplant infectious diseasesEffective antimicrobial therapyPositive blood culturesFast institutionSOT recipientsTransplant recipientsDiagnostic stewardshipBloodstream infectionsAntimicrobial therapyBlood culturesClinical guidanceOrgan transplantationConsensus conferenceClinical practiceInfectious diseasesClinical microbiologyAmerican SocietyTransplantationResistance detectionBacterial resistanceRecipientsDual organ transplantation: when heart alone is not enough
Nuqali A, Bellumkonda L. Dual organ transplantation: when heart alone is not enough. Current Opinion In Organ Transplantation 2023, 28: 370-375. PMID: 37582057, DOI: 10.1097/mot.0000000000001093.Peer-Reviewed Original ResearchConceptsDual-organ transplantationOrgan transplantationPatient selectionBetter long-term outcomesDual organ transplantsSingle organ transplantationTransplant center experienceLong-term outcomesAdvanced disease processLong-term managementPosttransplant outcomesCenter experienceImmunological advantageOrgan transplantsDisease processPartial toleranceSecond organPatientsTransplantationLack of standardizationOutcomesOrgansUrgent needTransplantNovel Strategies in Transplantation: Genetic Engineering and Vascularized Composite Allotransplantation
Kauke-Navarro M, Noel O, Knoedler L, Knoedler S, Panayi A, Stoegner V, Huelsboemer L, Pomahac B. Novel Strategies in Transplantation: Genetic Engineering and Vascularized Composite Allotransplantation. Journal Of Surgical Research 2023, 291: 176-186. PMID: 37429217, DOI: 10.1016/j.jss.2023.04.028.Peer-Reviewed Original ResearchConceptsImmunosuppressive regimensAllograft rejectionComposite allotransplantationDonor-derived immune cellsDonor-derived T lymphocytesRecipient-derived T cellsPotent immunosuppressive regimensToxic immunosuppressive regimensSolid organ transplantationAntigen-presenting cellsSystemic side effectsVascularized Composite AllotransplantationCD40 knockoutChronic rejectionRejection episodesSystemic immunosuppressionMost patientsImmunomodulatory strategiesTolerance inductionImmune cellsOrgan transplantationT cellsT lymphocytesSide effectsClinical successAssociation of Somatic ATP2A2 Damaging Variants With Grover Disease
Seli D, Ellis K, Goldust M, Shah K, Hu R, Zhou J, McNiff J, Choate K. Association of Somatic ATP2A2 Damaging Variants With Grover Disease. JAMA Dermatology 2023, 159: 745-749. PMID: 37195706, PMCID: PMC10193258, DOI: 10.1001/jamadermatol.2023.1139.Peer-Reviewed Original ResearchConceptsGrover's diseaseGD tissuesSomatic single nucleotide variantsControl tissuesRetrospective case seriesCase series studyAnnotation-dependent depletion scoreConsecutive patientsCase seriesKidney failureHistopathologic findingsAcantholytic disordersOrgan transplantationMAIN OUTCOMEBiopsy tissueSeries studyDarier's diseaseClinical diagnosisParticipant's DNAOlder individualsTissue DNADiseaseDisordersPatientsBiopsyThe association of cutaneous squamous cell carcinoma and basal cell carcinoma with solid organ transplantation: a cross‐sectional study of the All Of Us Research Program
Belzer A, Leasure A, Cohen J, Perkins S. The association of cutaneous squamous cell carcinoma and basal cell carcinoma with solid organ transplantation: a cross‐sectional study of the All Of Us Research Program. International Journal Of Dermatology 2023, 62: e564-e566. PMID: 37144784, DOI: 10.1111/ijd.16700.Peer-Reviewed Original ResearchCurrent Concepts in the Diagnosis and Management of Pneumocystis Pneumonia in Solid Organ Transplantation
Trubin P, Azar M. Current Concepts in the Diagnosis and Management of Pneumocystis Pneumonia in Solid Organ Transplantation. Infectious Disease Clinics Of North America 2023, 37: 617-640. PMID: 37142510, DOI: 10.1016/j.idc.2023.03.005.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSolid organ transplant recipientsOrgan transplant recipientsFirst-choice agentsSolid organ transplantationAppropriate clinical contextTransplant recipientsInterstitial pneumoniaTrimethoprim-sulfamethoxazoleOptimal treatmentPneumocystis pneumoniaOrgan transplantationInfection manifestsPrevention strategiesNucleic acid amplificationDiagnostic testingRadiographic imagingTissue samplingClinical contextLung fluidCurrent conceptsHost susceptibilityPneumoniaAcid amplificationTreatmentProphylaxisImpact of COVID‐19 on abdominal organ transplantation: A bibliometric analysis
Rawashdeh B, AlRyalat S, Abuassi M, Syaj S, Abu Jeyyab M, Pearson T, Kim J. Impact of COVID‐19 on abdominal organ transplantation: A bibliometric analysis. Transplant Infectious Disease 2023, 25: e14027. PMID: 36762493, DOI: 10.1111/tid.14027.Peer-Reviewed Original Research
2022
ESOT Consensus Platform for Organ Transplantation: Setting the Stage for a Rigorous, Regularly Updated Development Process
Cillo U, Weissenbacher A, Pengel L, Jochmans I, Roppolo D, Amarelli C, Belli L, Berenguer M, De Vries A, Ferrer J, Friedewald J, Furian L, Greenwood S, Monbaliu D, Nadalin S, Neyrinck A, Strazzabosco M, Toso C, Zaza G, Thuraisingham R, Berney T, Potena L, Montserrat N, Selzner N. ESOT Consensus Platform for Organ Transplantation: Setting the Stage for a Rigorous, Regularly Updated Development Process. Transplant International 2022, 35: 10915. PMID: 36406781, PMCID: PMC9667481, DOI: 10.3389/ti.2022.10915.Peer-Reviewed Original ResearchConceptsFirst consensus conferenceConsensus statementOrgan transplantationTransplant InternationalConsensus conferenceClinical practiceTransplantation fieldDevelopment of guidelinesTransplantationEuropean SocietyIndependent juryExpert opinionLiterature reviewFinal evidenceEvidenceGuidelinesReviewRecommendationsDepth evidenceRegulatory T Cells: Liquid and Living Precision Medicine for the Future of VCA
Kauke-Navarro M, Knoedler S, Panayi AC, Knoedler L, Noel OF, Pomahac B. Regulatory T Cells: Liquid and Living Precision Medicine for the Future of VCA. Transplantation 2022, 107: 86-97. PMID: 36210500, DOI: 10.1097/tp.0000000000004342.Peer-Reviewed Original ResearchConceptsSolid organ transplantationOrgan transplantationSide effectsField of VCAMedication side effectsBeneficial clinical effectsChimeric antigen receptorSevere side effectsRisk of infectionT cell receptorMaintenance immunosupressionMetabolic complicationsClinical effectsTransplant rejectionLifelong immunosuppressionImmune cellsTregsComposite allotransplantationSpecific antigenTherapeutic efficacyAntigen receptorStable levelPrecision medicineImmune system mechanismsImmunotoleranceImmunotolerance in liver transplantation: A primer for the clinician
Pérez-Escobar J, Jimenez J, Rodríguez-Aguilar E, Servín-Rojas M, Ruiz-Manriquez J, Safar-Boueri L, Carrillo-Maravilla E, Navasa M, García-Juárez I. Immunotolerance in liver transplantation: A primer for the clinician. Annals Of Hepatology 2022, 28: 100760. PMID: 36179797, DOI: 10.1016/j.aohep.2022.100760.Peer-Reviewed Original ResearchConceptsLiver transplant recipientsTransplant recipientsDevelopment of graft rejectionPharmacological interventionsAssociated with increased mortalityImmunosuppression withdrawal trialSolid organ transplantationRisk of rejectionMechanisms of immunotolerancePotential pharmacological interventionsImmunotolerance inductionGraft dysfunctionGraft injuryGraft rejectionImmunosuppressive medicationsOncological complicationsWithdrawal trialLiver transplantationTissue biomarkersClinical studiesImmunotoleranceOrgan transplantationImmunosuppressionAntimicrobial responsesTransplantationHumoral Immunogenicity to SARS-CoV-2 Vaccination in Liver Transplant Recipients: A Systematic Review and Meta-Analysis
Yoo J, Yon D, Lee S, Shin J, Kim B. Humoral Immunogenicity to SARS-CoV-2 Vaccination in Liver Transplant Recipients: A Systematic Review and Meta-Analysis. International Journal Of Biological Sciences 2022, 18: 5849-5857. PMID: 36263175, PMCID: PMC9576515, DOI: 10.7150/ijbs.77030.Peer-Reviewed Original ResearchConceptsOrthotopic liver transplant recipientsOrthotopic liver transplantationSARS-CoV-2 vaccinesHumoral immune response rateSolid organ transplant recipientsImmune response rateOrgan transplant recipientsTransplant recipientsOdds ratioAdverse eventsHealthy controlsSARS-CoV-2Response rateLiver transplant recipientsChronic kidney diseaseEvaluate immunogenicityLiver transplantationImmunosuppressive dosesSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Male sexPooled analysisRespiratory syndrome coronavirus 2Kidney diseaseOrgan transplantationFatal acute respiratory distress syndrome caused by blastomycosis after recent orthotopic liver transplantation in a non-endemic area
Sogawa H, Misawa R, Bodin R, Wolf D, Nog R, Kleinman G, Nishida S, Epelbaum O. Fatal acute respiratory distress syndrome caused by blastomycosis after recent orthotopic liver transplantation in a non-endemic area. Medical Mycology Case Reports 2022, 37: 37-40. PMID: 36035972, PMCID: PMC9399150, DOI: 10.1016/j.mmcr.2022.07.003.Peer-Reviewed Original ResearchAcute respiratory distress syndromeRespiratory distress syndromeFatal acute respiratory distress syndromeOrthotopic liver transplantationDistress syndromeLiver transplantationVeno-venous extracorporeal membrane oxygenationSolid organ transplantationExtracorporeal membrane oxygenationNon-endemic areasTraditional endemic areasMembrane oxygenationTransplant centersRisk factorsFulfilling criteriaOrgan transplantationEndemic areasTransplantationSyndromeBlastomycosisImmunosuppressionPneumoniaPatientsRecipientsCannabinoids and solid organ transplantation: Psychiatric perspectives and recommendations
Winder GS, Andrews SR, Banerjee AG, Hussain F, Ivkovic A, Kuntz K, Omary L, Shenoy A, Thant T, VandenBerg A, Zimbrean P. Cannabinoids and solid organ transplantation: Psychiatric perspectives and recommendations. Transplantation Reviews 2022, 36: 100715. PMID: 35853383, DOI: 10.1016/j.trre.2022.100715.Peer-Reviewed Original ResearchConceptsSolid organ transplantationCannabinoid useOrgan transplantationClinical careUS transplantation centersSOT patientsKidney transplantationTransplantation centersCannabinoid effectsClinical impactClinicians' perceptionsMedical literaturePatientsTransplantationCliniciansCannabinoidsCareInterprofessional issuesPsychiatric perspectiveFuture studiesUse ratesProfessional societiesSystematized reviewOngoing dilemmaRecommendations
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply