2021
Moderate alcohol intake associates with a decreased risk of venous thrombosis: mediation through decreased stress-associated brain activity
Mezue K, Osborne M, Abbasi T, Zureigat H, Abohashem S, Gharios C, Akuffo E, Cardeiro A, Pitman R, Shin L, Jaffer F, Rosovsky R, Tawakol A. Moderate alcohol intake associates with a decreased risk of venous thrombosis: mediation through decreased stress-associated brain activity. European Heart Journal 2021, 42: ehab724.2046. DOI: 10.1093/eurheartj/ehab724.2046.Peer-Reviewed Original ResearchModerate alcohol intakeDeep venous thrombosisAlcohol intakeNeural activityEffects of alcoholEffects of moderate alcoholVenous thrombosisDecreased riskNeural effectsMedian follow-up periodDeep venous thrombosis riskBrain activityMediation analysisRisk of deep venous thrombosisIncidence of deep venous thrombosisRisk of venous thrombosisDecreased risk of venous thrombosisAdult participantsEmission Tomography ImagingCox regression analysisFollow-up periodNeural pathwaysNeurobiological activityFollow-up outcome informationModerate alcohol
2002
Effect of tamoxifen on venous thrombosis risk factors in women without cancer: the Breast Cancer Prevention Trial
Cushman M, Costantino J, Bovill E, Wickerham D, Buckley L, Roberts J, Krag D. Effect of tamoxifen on venous thrombosis risk factors in women without cancer: the Breast Cancer Prevention Trial. British Journal Of Haematology 2002, 120: 109-116. PMID: 12492585, DOI: 10.1046/j.1365-2141.2003.03976.x.Peer-Reviewed Original ResearchConceptsBreast Cancer Prevention TrialVenous thrombosis risk factorsActivated Protein CEffects of tamoxifenCancer Prevention TrialThrombosis risk factorsRisk factorsProtein CProtein SVenous thrombosisTamoxifen reduces breast cancer incidenceIncreased riskIncreased risk of venous thrombosisPrevention trialsActivated protein C resistanceRisk of venous thrombosisPlacebo-treated womenReduction of antithrombinTamoxifen-treated womenDouble-blind fashionMonths of treatmentActivated protein C ratioBreast cancer incidenceProtein C antigenBody mass index
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