2025
High- vs low-dose oxytocin protocols for labor induction: a systematic review and meta-analysis
Grasch J, Costantine M, Cahill A, Subramaniam A, Son M, Raghuraman N, Grobman W, Frey H. High- vs low-dose oxytocin protocols for labor induction: a systematic review and meta-analysis. American Journal Of Obstetrics & Gynecology MFM 2025, 7: 101691. PMID: 40334983, DOI: 10.1016/j.ajogmf.2025.101691.Peer-Reviewed Original ResearchConceptsLow-dose oxytocin protocolsOxytocin protocolInduction of laborLabor inductionCesarean deliveryLow-dose protocolVaginal deliveryNeonatal outcome of inductionFrequency of postpartum hemorrhageRisk of cesarean deliveryLikelihood of cesarean deliveryDuration of labor inductionFrequency of cesarean deliveryHigh-dose oxytocin protocolRelative riskCochrane risk of bias assessment toolSystematic reviewRisk of bias assessment toolOxytocin infusion protocolOperative vaginal deliveryHigh-dose oxytocinConfidence intervalsDuration of laborOutcome of inductionHigh risk of bias
2024
Induction of labor vs expectant management among low-risk patients with 1 prior cesarean delivery
Ukoha E, Wen T, Reddy U. Induction of labor vs expectant management among low-risk patients with 1 prior cesarean delivery. American Journal Of Obstetrics And Gynecology 2024, 232: 321.e1-321.e10. PMID: 38852849, DOI: 10.1016/j.ajog.2024.06.001.Peer-Reviewed Original ResearchInduction of laborNeonatal morbidity compositeOperative vaginal deliveryMaternal morbidity compositeVaginal deliveryExposure of interestCesarean deliveryIntensive care unit admissionMorbidity compositeWeeks 6 daysWeeks 0 daysExpectant management groupLow-risk patientsPeripartum hysterectomyUterine ruptureLikelihood of vaginal deliveryRate of uterine ruptureUnit admissionElective induction of laborLog-binomial regression modelsBirth certificate dataConfidence intervalsExpectant managementAssociated with increased likelihoodNeonatal morbidity outcomesExploring Effect of Patient Counseling on Mode of Delivery After Cesarean Section [ID 2683575]
Pondugula N, Greenberg J, Illuzzi J, Adeyemo O. Exploring Effect of Patient Counseling on Mode of Delivery After Cesarean Section [ID 2683575]. Obstetrics And Gynecology 2024, 143: 54s-54s. DOI: 10.1097/01.aog.0001013692.09625.74.Peer-Reviewed Original ResearchCesarean delivery rateBody mass indexMode of deliveryVaginal deliveryNational cesarean delivery rateHistory of VBACIncreasing vaginal birthEffect of patient counselingHistory of vaginal deliveryIncreased BMIDelivery rateVBAC ratesVaginal birthTOLACVBACAntepartum counselingCesarean deliveryAssociated with ageDocumented counselingObstetric dataCounseling documentationMedicaid insuranceInsurance typeInclusion criteriaMass indexPeripartum interventions for people with class III obesity: a systematic review and meta-analysis
Kominiarek M, Espinal M, Cassimatis I, Peace J, Premkumar A, Toledo P, Shramuk M, Wafford E. Peripartum interventions for people with class III obesity: a systematic review and meta-analysis. American Journal Of Obstetrics & Gynecology MFM 2024, 6: 101354. PMID: 38494155, DOI: 10.1016/j.ajogmf.2024.101354.Peer-Reviewed Original ResearchConceptsRandomized Controlled TrialsCesarean deliveryProphylactic negative-pressure wound therapyControlled TrialsMeta-analysisPeripartum interventionsCohort studyPlanned vaginal deliveryCesarean delivery techniquesPlanned cesarean deliveryNegative-pressure wound therapySurgical site infectionOutcomes of peopleWound morbidityClass III obesityPooled risk ratioLabor inductionSite infectionVaginal deliveryWound therapySystematic reviewInclusion criteriaRisk ratioCesareanIII obesityThe optimal cutoff for intertwin delivery interval: A retrospective cohort study
Justman N, Somer S, Goldfreind R, Abu‐Rass H, Siegler Y, Shahak G, Bachar G, Copel J, Zipori Y, Khatib N, Weiner Z, Vitner D. The optimal cutoff for intertwin delivery interval: A retrospective cohort study. International Journal Of Gynecology & Obstetrics 2024, 166: 760-766. PMID: 38258901, DOI: 10.1002/ijgo.15382.Peer-Reviewed Original ResearchIntertwin delivery intervalNeonatal outcomesCesarean deliveryDelivery intervalVaginal deliveryReceiver Operating CharacteristicNeonatal acidemiaRate of cesarean deliveryApgar scoreVaginal delivery of twinsStage of laborPrevent adverse neonatal outcomesPlacental abruption rateAdverse neonatal outcomesDelivery of twinsTertiary care centerAssociated with increased ratesRetrospective cohort studyYouden's J statisticPlacental abruptionTwin pregnanciesCohort studyCare centerOptimal cutoffCutoff point
2023
Thromboembolic Disorders
Merriam A, Pettker C. Thromboembolic Disorders. 2023, 123-133. DOI: 10.1002/9781119636540.ch15.Peer-Reviewed Original ResearchVenous thromboembolismPulmonary embolismLeading causeDeep venous thrombosisCommon physical symptomsOperative vaginal deliveryPregnancy-specific risk factorsMaternal morbidityCesarean deliveryMultiple gestationsMaternal deathsVaginal deliveryVenous thrombosisPostpartum hemorrhageMaternal mortalityNonpregnant individualsThrombotic riskPostpartum periodRisk factorsThromboembolic disordersLow prevalencePhysical symptomsPregnancySymptomsThromboembolismMotivations and demographic differences in pregnant individuals in the decision to participate in research
Scott T, Mercedes C, Lin H, Katz D. Motivations and demographic differences in pregnant individuals in the decision to participate in research. Journal Canadien D'anesthésie 2023, 71: 87-94. PMID: 37919628, DOI: 10.1007/s12630-023-02635-8.Peer-Reviewed Original ResearchConceptsPregnant individualsDemographic associationsResultsThe survey response rateSelf-reported demographicsSurvey response ratePredictive of participationNon-HispanicPatients' reasonsVaginal deliverySurvey-based studyResearch studiesInfluence participationScreening failureSurvey responsesParticipantsActive participationDemographic differencesBachelor's degreeNon-blacksResponse ratePreservative-free morphineConclusionsThese findingsSurveyClinical difficultiesIndividualsRace and Intention to Breastfeed are the Strongest Predictors of Exclusive Breastfeeding: a Retrospective Study
Sartor L, Pyram-Vincent C, Lin H, Ouyang Y, Wax D, Beilin Y. Race and Intention to Breastfeed are the Strongest Predictors of Exclusive Breastfeeding: a Retrospective Study. Journal Of Racial And Ethnic Health Disparities 2023, 11: 3704-3713. PMID: 37796430, DOI: 10.1007/s40615-023-01819-8.Peer-Reviewed Original ResearchConceptsBlack patientsInitiation of skin-to-skin contactPredictors of EBFFeeding practicesSkin-to-skin contactSkin-to-skinIn-hospital practiceFisher's exact statistical testsElectronic medical recordsRacial groupsConclusionsThe main findingFeeding planVaginal deliveryNeonatal careRetrospective studyRace/ethnic groupsStudy criteriaExclusive breastfeedingWhite patientsIntroductionRacial disparitiesStrongest predictorsPatientsMedical recordsResultsThe studyBreastfeedingDesirability of outcome ranking for obstetrical trials: illustration and application to the ARRIVE trial
SANDOVAL G, GROBMAN W, EVANS S, RICE M, CLIFTON R, CHAUHAN S, COSTANTINE M, GIBSON K, LONGO M, METZ T, MILLER E, PARRY S, REDDY U, ROUSE D, SIMHAN H, THORP J, TITA A, SAADE G, Network E. Desirability of outcome ranking for obstetrical trials: illustration and application to the ARRIVE trial. American Journal Of Obstetrics And Gynecology 2023, 230: 370.e1-370.e12. PMID: 37741532, PMCID: PMC10939984, DOI: 10.1016/j.ajog.2023.09.016.Peer-Reviewed Original ResearchElective inductionARRIVE trialCesarean deliverySecondary outcomesPrimary outcomeVaginal deliveryDesirability of outcomeEunice Kennedy Shriver National InstituteSpontaneous vaginal deliverySevere neonatal complicationsWeeks of gestationOperative vaginal deliveryBetter overall outcomesPerson-centred careNeonatal complicationsObstetric trialsExpectant managementPerinatal deathRandomized trialsDecreased riskPoor outcomeClinical trialsChild healthTreatment scoresOutcome rankingsAssociation of maternal body mass index with success and outcomes of attempted operative vaginal delivery
Grasch J, Venkatesh K, Grobman W, Silver R, Saade G, Mercer B, Yee L, Scifres C, Parry S, Simhan H, Reddy U, Frey H. Association of maternal body mass index with success and outcomes of attempted operative vaginal delivery. American Journal Of Obstetrics & Gynecology MFM 2023, 5: 101081. PMID: 37422004, DOI: 10.1016/j.ajogmf.2023.101081.Peer-Reviewed Original ResearchConceptsMaternal body mass indexBody mass indexOperative vaginal deliveryVaginal delivery attemptComposite maternal morbidityComposite neonatal morbidityVaginal deliveryMass indexNeonatal morbidityCesarean deliveryMaternal morbidityAdverse outcomesSecond-stage cesarean deliveryBody mass index groupsBody mass index categoriesNulliparous Pregnancy Outcomes StudyNonanomalous singleton pregnanciesNeonatal adverse outcomesMultivariable logistic regressionPregnancy Outcomes StudyNulliparous individualsDose-dependent mannerSecondary outcomesSingleton pregnanciesPrimary outcomeMaternal and Delivery Characteristics and Self-Reported Perceived Control During Labor
Mallett G, Hill K, Doherty L, Grobman W, Reddy U, Tita A, Silver R, Rice M, El-Sayed Y, Wapner R, Rouse D, Saade G, Thorp J, Chauhan S, Costantine M, Chien E, Casey B, Srinivas S, Swamy G, Simhan H, Macones G. Maternal and Delivery Characteristics and Self-Reported Perceived Control During Labor. Obstetrics And Gynecology 2023, 142: 117-124. PMID: 37290106, PMCID: PMC10330140, DOI: 10.1097/aog.0000000000005230.Peer-Reviewed Original ResearchConceptsBody mass indexWeeks of gestationLabor Agentry ScaleScale scoreLabor painPrivate health insuranceDelivery characteristicsLabor pain scoresPrevious pregnancy lossSpontaneous vaginal deliverySevere neonatal complicationsHealth insuranceMode of deliveryFinal multivariable modelMultivariable linear regressionSelf-administered questionnaireSelf-reported raceNeonatal complicationsExpectant managementPain scoresLabor inductionNonprivate insuranceOperative deliveryCesarean deliveryVaginal deliveryOutcomes of induction vs prelabor cesarean delivery at <33 weeks for hypertensive disorders of pregnancy
Bushman E, Grobman W, Bailit J, Reddy U, Wapner R, Varner M, Thorp J, Caritis S, Prasad M, Saade G, Sorokin Y, Rouse D, Blackwell S, Tolosa J, Network E. Outcomes of induction vs prelabor cesarean delivery at <33 weeks for hypertensive disorders of pregnancy. American Journal Of Obstetrics & Gynecology MFM 2023, 5: 101032. PMID: 37244639, PMCID: PMC10521213, DOI: 10.1016/j.ajogmf.2023.101032.Peer-Reviewed Original ResearchConceptsPrelabor cesarean deliveryHypertensive disordersInduction of laborCesarean deliveryLabor inductionNeonatal morbidityInduction groupMedian durationVaginal deliveryWeeks' gestationSecondary analysisAdverse composite outcomeComposite maternal morbidityOutcome of inductionPreterm hypertensive disordersHalf of patientsCesarean delivery groupLength of inductionOptimal delivery approachMaternal morbidityComposite outcomeFetal malpresentationMultiple gestationsPreterm birthSecondary outcomesSmall Bowel Obstruction in Postpartum Vaginal Delivery due to Prior Abdominal Adhesions Case Report
Yang L, Kao L. Small Bowel Obstruction in Postpartum Vaginal Delivery due to Prior Abdominal Adhesions Case Report. Case Reports In Obstetrics And Gynecology 2023, 2023: 6563205. PMID: 37025389, PMCID: PMC10072967, DOI: 10.1155/2023/6563205.Peer-Reviewed Case Reports and Technical NotesSmall bowel obstructionUncomplicated vaginal deliveryVaginal deliveryBowel obstructionIntestinal obstructionInitial abdominal X-rayComputed tomography abdomenNonspecific abdominal painAbdominal X-rayPrior appendectomyTomography abdomenAbdominal painMultiparous womenCT abdomenSurgical repairAppendectomy surgeryExam findingsCase reportRisk factorsObstructionAbdomenDeliveryAppendectomyPainSurgeryRisk of Spontaneous Obstetric Anal Sphincter Injury Following Non-Operative Vaginal Delivery in a High-Risk Cohort.
Polnaszek B, Danilack V, Has P, Russo M, Hamel M, Tuuli M, Savitz D, Lewkowitz A. Risk of Spontaneous Obstetric Anal Sphincter Injury Following Non-Operative Vaginal Delivery in a High-Risk Cohort. Rhode Island Medical Journal 2023, 106: 43-44. PMID: 36848543, PMCID: PMC10408132.Peer-Reviewed Original ResearchMaximum Dose Rate of Intrapartum Oxytocin Infusion and Associated Obstetric and Perinatal Outcomes
Son M, Roy A, Grobman W, Miller E, Dude A, Peaceman A, Stetson B. Maximum Dose Rate of Intrapartum Oxytocin Infusion and Associated Obstetric and Perinatal Outcomes. Obstetrics And Gynecology 2023, 141: 379-386. PMID: 36649339, DOI: 10.1097/aog.0000000000005058.Peer-Reviewed Original ResearchConceptsTitration regimenCesarean deliveryVaginal deliveryMultivariable analysisAdverse outcomesNeonatal intensive care unit admissionComposite severe neonatal morbidityIntensive care unit admissionSecondary analysisCumulative proportionPerinatal adverse outcomesCare unit admissionSevere neonatal morbiditySpontaneous vaginal deliveryMagnesium sulfate infusionUnderwent cesarean deliveryRupture of membranesWeeks of gestationNICU admissionUnit admissionHypertensive disordersLack of evidenceNeonatal morbidityNulliparous patientsPerinatal outcomes
2022
Mode of Delivery in Antepartum Singleton Stillbirths and Associated Risk Factors
Underwood K, Reddy UM, Hosier H, Sweeney L, Campbell KH, Xu X. Mode of Delivery in Antepartum Singleton Stillbirths and Associated Risk Factors. American Journal Of Perinatology 2022, 41: e193-e203. PMID: 35850142, DOI: 10.1055/s-0042-1750795.Peer-Reviewed Original ResearchMode of deliveryAntepartum stillbirthCesarean deliveryPrior cesareanVaginal deliveryMaternal hospital discharge recordsLower likelihoodAssociated risk factorsWeeks of gestationHospital discharge recordsNon-clinical factorsUrban teaching hospitalMultivariable regression analysisPopulation-based sampleFetal death certificatesSingleton stillbirthsPrimary outcomeHospital characteristicsRisk factorsTeaching hospitalDeath certificatesMultivariable regressionCesareanPatientsStillbirth
2021
Intraventricular haemorrhage in a Ugandan cohort of low birth weight neonates: the IVHU study
MacLeod R, Paulson J, Okalany N, Okello F, Acom L, Ikiror J, Cowan F, Tann C, Dyet L, Hagmann C, Burgoine K. Intraventricular haemorrhage in a Ugandan cohort of low birth weight neonates: the IVHU study. BMC Pediatrics 2021, 21: 12. PMID: 33407279, PMCID: PMC7786968, DOI: 10.1186/s12887-020-02464-4.Peer-Reviewed Original ResearchConceptsRisk of intraventricular haemorrhageLow birth weight neonatesIntraventricular haemorrhageNeonatal unitAntenatal steroidsOdds ratioGestational ageCranial ultrasoundRisk factorsProspective cohort study of neonatesAssociated with intraventricular haemorrhageCohort study of neonatesDoses of antenatal steroidsPrevention of intraventricular haemorrhageRates of SGA neonatesSeverity of intraventricular haemorrhageDay 7Study of neonatesProspective cohort studyLow-income countriesDay of recruitmentModifiable risk factorsRegional Referral HospitalSGA neonatesVaginal delivery
2020
Term Labor Induction and Cesarean Delivery Risk among Obese Women with and without Comorbidities
Glazer K, Danilack V, Field A, Werner E, Savitz D. Term Labor Induction and Cesarean Delivery Risk among Obese Women with and without Comorbidities. American Journal Of Perinatology 2020, 39: 154-164. PMID: 32722823, DOI: 10.1055/s-0040-1714422.Peer-Reviewed Original ResearchConceptsCesarean delivery riskLow-risk nulliparous womenPrior vaginal deliveryCesarean riskCesarean deliveryLabor inductionElective inductionNulliparous womenVaginal deliveryWeeks' gestationMaternal ageTerm inductionEarly term inductionTerm labor inductionPrior cesarean deliveryAdjusted risk ratioBody mass indexElective labor inductionWeeks of gestationDelivery riskRisk reductionARRIVE trialExpectant managementHypertensive disordersObstetric populationPrediction Model for Vaginal Birth After Induction of Labor in Women With Hypertensive Disorders of Pregnancy.
Beninati M, Ramos S, Danilack V, Has P, Savitz D, Werner E. Prediction Model for Vaginal Birth After Induction of Labor in Women With Hypertensive Disorders of Pregnancy. Obstetrics And Gynecology 2020, 136: 402-410. PMID: 32649502, DOI: 10.1097/aog.0000000000003938.Peer-Reviewed Original ResearchConceptsInduction of laborCesarean deliveryHypertensive disordersVaginal deliveryHosmer-Lemeshow testLabor inductionIntrapartum magnesium sulfateStepwise backward logistic regressionVaginal delivery successPrior cesarean deliveryBody mass indexPrelabor cesarean deliveryWeeks of gestationBackward logistic regressionFuture external validationSimilar discriminatory abilitySeizure prophylaxisCervical ripeningRetrospective cohortSingleton pregnanciesSpontaneous laborGestational ageMass indexStudy cohortVaginal birthStroke in Pregnancy: A Focused Update.
Miller EC, Leffert L. Stroke in Pregnancy: A Focused Update. Anesthesia & Analgesia 2020, 130: 1085-1096. PMID: 31124843, PMCID: PMC7035913, DOI: 10.1213/ane.0000000000004203.Peer-Reviewed Original ResearchConceptsHemorrhagic strokeCesarean deliveryPregnant womenIschemic strokeGeneral anesthesiaObstetric anesthesiologistHigh-risk obstetriciansLarge stroke trialsPregnancy-related strokeHigh-risk groupRisk of herniationMaternal strokeObstetric indicationsTherapeutic anticoagulationExtremity weaknessStroke neurologistsAcute strokeDevastating complicationNeuraxial analgesiaNonpregnant womenStroke subtypesIntracranial hypertensionRecent strokeVaginal deliveryStroke trials
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