2025
A sibling study of the prenatal and perinatal risks for cerebral palsy
Zhuo H, Rogne T, Liew Z. A sibling study of the prenatal and perinatal risks for cerebral palsy. Pediatric Research 2025, 1-8. PMID: 40316681, DOI: 10.1038/s41390-025-04055-4.Peer-Reviewed Original ResearchSibling comparison designCerebral palsyLow Apgar scoreMaternal pregnancy complicationsSibling designPerinatal factorsAssociated with CPApgar scoreComparison designPregnancy complicationsOdds ratioPreterm birthAttenuated to nullConfidence intervalsPre-pregnancy overweightLifestyle-related factorsCP riskSibling comparison studiesSibling-comparison designGestational ageMaternal cigarette smokingSingleton birthsCP etiologyInterpretation of findingsPre-pregnancyHigh- vs low-dose oxytocin regimens for labor augmentation: a systematic review and meta-analysis
Logue T, Zullo F, van Biema F, Son M, London L, Paranandi S, Sciscione A, Rizzo G, Mascio D, Chauhan S. High- vs low-dose oxytocin regimens for labor augmentation: a systematic review and meta-analysis. American Journal Of Obstetrics & Gynecology MFM 2025, 7: 101604. PMID: 39788427, DOI: 10.1016/j.ajogmf.2025.101604.Peer-Reviewed Original ResearchConceptsHigh-dose oxytocin regimenRisk of low Apgar scoreOxytocin regimensLabor augmentationApgar score <7Low-dose regimensUmbilical artery pH <Cesarean deliveryLow Apgar scoreArterial pH <High-dose regimensOxytocin doseAugmentation of laborControlled TrialsHead-to-head meta-analysesAdverse labor outcomesContinuous oxytocin infusionCoprimary outcomesNeonatal acidosisApgar scoreRandom-effect head-to-head meta-analysesMeta-analysisIncidence of Apgar score < 7Quasi-randomized controlled trialsRandomized Controlled Trials
2024
Prophylactic Red Cell Exchange: Preventing Complications in Pregnant Patients with Sickle Cell Disease
Sariipek N, Horstman E, Tormey C, Yurtsever N. Prophylactic Red Cell Exchange: Preventing Complications in Pregnant Patients with Sickle Cell Disease. Blood 2024, 144: 5340-5340. DOI: 10.1182/blood-2024-198650.Peer-Reviewed Original ResearchRed cell exchangeManagement of pregnancy-related complicationsSickle cell diseasePre-eclampsiaPregnancy-related complicationsCesarean sectionCell diseaseApgar scoreHealthy infantsPainful crisesBilateral retinal vein occlusionAmerican Society for Apheresis guidelinesSpectra Optia apheresis systemHematocrit levelsEmergency cesarean sectionRetinal artery occlusionRetinal vein occlusionBilateral renal infarctionSickle cell-related complicationsHistory of retinopathyPrevent pre-eclampsiaSecond-line therapyTransient vision lossWeeks of gestationPregnancy related complicationsShort-term effects of wildfire-specific fine particulate matter and its carbonaceous components on perinatal outcomes: A multicentre cohort study in New South Wales, Australia
Nyadanu S, Foo D, Pereira G, Mickley L, Feng X, Bell M. Short-term effects of wildfire-specific fine particulate matter and its carbonaceous components on perinatal outcomes: A multicentre cohort study in New South Wales, Australia. Environment International 2024, 191: 109007. PMID: 39278048, DOI: 10.1016/j.envint.2024.109007.Peer-Reviewed Original ResearchConceptsAdjusted hazard ratiosLow 5-min Apgar scoreCarbonaceous componentsPerinatal outcomesOrganic carbonNew South WalesNonvertex presentationCaesarean sectionPositive associationApgar scorePreterm birthBlack carbon componentsShort-term effectsLow socioeconomic statusSouth WalesAdverse perinatal outcomesMulticentre cohort studyWildfire seasonBenefit public healthCox regression modelsIntensive care unitSingleton birthsBlack carbonSocioeconomic statusGestational weeksAssociation Between Intrapartum Nitrous Oxide for Labor Analgesia and Short-Term Neonatal Outcomes
Starosta A, Lundsberg L, Culhane J, Partridge C, Grechukhina O, Son M. Association Between Intrapartum Nitrous Oxide for Labor Analgesia and Short-Term Neonatal Outcomes. Obstetrics And Gynecology 2024, 143: 677-682. PMID: 38484306, DOI: 10.1097/aog.0000000000005554.Peer-Reviewed Original ResearchShort-term neonatal outcomesNeonatal intensive care unitNo analgesiaNeonatal outcomesApgar scoreLabor analgesiaComposite outcomeAdverse short-term neonatal outcomesNeonatal intensive care unit admissionSecondary outcomesSingle-center retrospective cohortRetrospective cohort study of individualsCohort study of individualsLow-risk patientsRetrospective cohort studyIntensive care unitElectronic medical recordsNitrous oxide useAnalgesia typeIntrapartum cesareanSingleton gestationsNICU admissionNitrous oxide exposureIntrapartum analgesiaNeonatal hyperbilirubinemiaThe optimal cutoff for intertwin delivery interval: A retrospective cohort study
Justman N, Somer S, Goldfreind R, Abu‐Rass H, Siegler Y, Shahak G, Bachar G, Copel J, Zipori Y, Khatib N, Weiner Z, Vitner D. The optimal cutoff for intertwin delivery interval: A retrospective cohort study. International Journal Of Gynecology & Obstetrics 2024, 166: 760-766. PMID: 38258901, DOI: 10.1002/ijgo.15382.Peer-Reviewed Original ResearchIntertwin delivery intervalNeonatal outcomesCesarean deliveryDelivery intervalVaginal deliveryReceiver Operating CharacteristicNeonatal acidemiaRate of cesarean deliveryApgar scoreVaginal delivery of twinsStage of laborPrevent adverse neonatal outcomesPlacental abruption rateAdverse neonatal outcomesDelivery of twinsTertiary care centerAssociated with increased ratesRetrospective cohort studyYouden's J statisticPlacental abruptionTwin pregnanciesCohort studyCare centerOptimal cutoffCutoff point
2023
Reduced Compared With Traditional Schedules for Routine Antenatal Visits
Balk E, Danilack V, Bhuma M, Cao W, Adam G, Konnyu K, Peahl A. Reduced Compared With Traditional Schedules for Routine Antenatal Visits. Obstetrics And Gynecology 2023, 142: 8-18. PMID: 37290105, DOI: 10.1097/aog.0000000000005193.Peer-Reviewed Original ResearchConceptsRoutine antenatal visitsAntenatal care visitsVisit scheduleAntenatal visitsAntenatal careCare visitsGestational ageNeonatal intensive care unit admissionIntensive care unit admissionRoutine antenatal care visitsCare unit admissionLow Apgar scoreLow birth weightHealth care utilizationNonrandomized comparative studyTraditional schedulePatient experience measuresUnit admissionApgar scorePreterm birthBirth outcomesCare utilizationCochrane DatabaseBirth weightSTUDY SELECTIONOutcomes among Neonates after a Diagnosis of Persistent or Transient Fetal Growth Restriction Delivered at Term
Ramos S, Has P, Gimovsky A, Danilack V, Savitz D, Lewkowitz A. Outcomes among Neonates after a Diagnosis of Persistent or Transient Fetal Growth Restriction Delivered at Term. American Journal Of Perinatology 2023, 41: e1470-e1477. PMID: 36894159, PMCID: PMC10562520, DOI: 10.1055/a-2051-3859.Peer-Reviewed Original ResearchFetal growth restrictionLater gestational agesNeonatal outcomesGestational ageNeonatal morbidityGrowth restrictionAbnormal umbilical artery Doppler studyExact testNeonatal intensive care unit admissionIntensive care unit admissionUmbilical artery Doppler studiesHigher Body Mass IndexComposite neonatal outcomeCare unit admissionTertiary care centerRespiratory distress syndromeBody mass indexMode of deliveryFisher's exact testComposite morbidityFGR pregnanciesLast ultrasoundUnit admissionApgar scoreDelivery complications
2022
Duration of Exposure to General Endotracheal Anesthesia During Cesarean Deliveries at Term and Perinatal Complications
Swanson K, Liang L, Grobman W, Higgins N, Roy A, Son M. Duration of Exposure to General Endotracheal Anesthesia During Cesarean Deliveries at Term and Perinatal Complications. Obstetrical & Gynecological Survey 2022, 77: 453-455. DOI: 10.1097/01.ogx.0000852896.18085.ad.Peer-Reviewed Original Research
2021
Duration of Exposure to General Endotracheal Anesthesia during Cesarean Deliveries at Term and Perinatal Complications
Swanson K, Liang L, Grobman WA, Higgins N, Roy A, Son M. Duration of Exposure to General Endotracheal Anesthesia during Cesarean Deliveries at Term and Perinatal Complications. American Journal Of Perinatology 2021, 39: 232-237. PMID: 34844279, DOI: 10.1055/s-0041-1739355.Peer-Reviewed Original ResearchConceptsGeneral endotracheal anesthesiaPrimary perinatal outcomeCesarean deliveryPerinatal complicationsPerinatal outcomesDuration of exposureMaternal morbidityMultivariable analysisGeneral anesthesiaEndotracheal anesthesiaFetal statusSingle tertiary care centerComposite of complicationsPrior abdominal surgeryTertiary care centerWeeks of gestationMaternal complicationsNonanomalous gestationsApgar scoreMultivariable adjustmentSecondary outcomesAbdominal surgeryBivariable analysisRetrospective studyCare centerSelf-reported medicinal plant use by Ghanaian women during pregnancy is associated with poor neonatal health
Busse C, Wilson M, Bakari A, Moyer C. Self-reported medicinal plant use by Ghanaian women during pregnancy is associated with poor neonatal health. Journal Of Public Health 2021, 44: 319-328. PMID: 33782702, DOI: 10.1093/pubmed/fdab033.Peer-Reviewed Original ResearchConceptsHerb useGhanaian womenUrban government hospitalNon-usersConditional logistic regressionCross-sectional studyAssociated with poor neonatal outcomesUrban African womenLow Apgar scoreHerb usersSingleton birthsNeonatal healthPoor neonatal outcomeSociodemographic variablesGovernment hospitalsMaternal interviewsBaby's birthweightMother's ageLogistic regressionNeonatal outcomesApgar scorePregnant womenChart reviewNeonatal birthweightWomen
2020
Acute Brain Injury in Infant Venoarterial Extracorporeal Membrane Oxygenation: An Autopsy Study.
Caturegli G, Cho S, White B, Chen L. Acute Brain Injury in Infant Venoarterial Extracorporeal Membrane Oxygenation: An Autopsy Study. Pediatric Critical Care Medicine 2020, 22: 297-302. PMID: 33055528, DOI: 10.1097/pcc.0000000000002573.Peer-Reviewed Original ResearchConceptsExtracorporeal membrane oxygenationVenoarterial extracorporeal membrane oxygenationAcute brain injuryHypoxic-ischemic brain injuryMembrane oxygenationMedian ageIntracranial hemorrhageExtracorporeal membrane oxygenation support durationExtracorporeal membrane oxygenation durationExtracorporeal membrane oxygenation initiationExtracorporeal membrane oxygenation patientsBrain injuryElevated liver enzymesAssociated with acute brain injuryApgar scoreGestational ageOxygenation durationTiming of acute brain injuryHepatic impairmentAnticoagulant therapyPathology recordsBirth weightOxygenation patientsOxygenation initiationAutopsied patients
2017
Markers of Successful Extubation in Extremely Preterm Infants, and Morbidity After Failed Extubation
Chawla S, Natarajan G, Shankaran S, Carper B, Brion L, Keszler M, Carlo W, Ambalavanan N, Gantz M, Das A, Finer N, Goldberg R, Cotten C, Higgins R, Network E, Jobe A, Caplan M, Polin R, Laptook R, Oh W, Hensman A, Gingras D, Barnett S, Lillie S, Francis K, Andrews D, Angela K, Walsh M, Fanaroff A, Newman N, Siner B, Schibler K, Donovan E, Narendran V, Bridges K, Alexander B, Grisby C, Mersmann M, Mincey H, Hessling J, Goldberg R, Auten K, Fisher K, Foy K, Siaw G, Stoll B, Buchter S, Piazza A, Carlton D, Hale E, Archer S, Poindexter B, Lemons J, Hamer F, Herron D, Miller L, Wilson L, Berberich M, Blaisdell C, Gail D, Kiley J, Poole W, Cunningham M, Hastings B, Irene A, Auman J, Huitema C, Pickett J, Wallace D, Zaterka-Baxter K, Van Meurs K, Stevenson D, Ball M, Proud M, Frantz I, Fiascone J, Furey A, MacKinnon B, Nylen E, Collins M, Cosby S, Phillips V, Rasmussen M, Wozniak P, Rich W, Arnell K, Bridge R, Demetrio C, Bell E, Widness J, Klein J, Johnson K, Duara S, Everett-Thomas R, Watterberg K, Ohls R, Rohr J, Lacy C, Phelps D, Laroia N, Reubens L, Burnell E, Sánchez P, Rosenfeld C, Salhab W, Allen J, Guzman A, Hensley G, Lepps M, Martin M, Miller N, Solis A, Vasil D, Wilder K, Kennedy K, Tyson J, Morris B, Harris B, Lis A, Martin S, McDavid G, Tate P, Wright S, Yoder B, Faix R, Burnett J, Jensen J, Osborne K, Spencer C, Weaver-Lewis K, O'Shea T, Peters N, Sood B, Bara R, Billian E, Johnson M, Ehrenkranz R, Jacobs H, Bhandari V, Cervone P, Gettner P, Konstantino M, Poulsen J, Taft J. Markers of Successful Extubation in Extremely Preterm Infants, and Morbidity After Failed Extubation. The Journal Of Pediatrics 2017, 189: 113-119.e2. PMID: 28600154, PMCID: PMC5657557, DOI: 10.1016/j.jpeds.2017.04.050.Peer-Reviewed Original ResearchConceptsGestational age statusHours of ageSuccessful extubationExtubation failureApgar scoreBronchopulmonary dysplasiaPreterm infantsContinuous positive airway pressure groupOxygenation Randomized TrialExtremely preterm infantsDay of extubationAge statusHigher adjusted ratesEarly surfactantExtubation criteriaExtubation statusFailed ExtubationNeonatal morbidityPreterm neonatesVentilatory strategiesElective extubationWeeks' gestationRandomized trialsAdjusted ratesExtubation
2015
A Randomized Trial of Intrapartum Fetal ECG ST-Segment Analysis
Belfort M, Saade G, Thom E, Blackwell S, Reddy U, Thorp J, Tita A, Miller R, Peaceman A, McKenna D, Chien E, Rouse D, Gibbs R, El-Sayed Y, Sorokin Y, Caritis S, VanDorsten J. A Randomized Trial of Intrapartum Fetal ECG ST-Segment Analysis. Obstetrical & Gynecological Survey 2015, 70: 735-737. DOI: 10.1097/ogx.0000000000000276.Peer-Reviewed Original ResearchST-segment analysisFetal ECG ST segment analysisElectronic fetal monitoringApgar scoreCesarean deliveryNeonatal encephalopathyOperative deliveryPrimary outcomeVaginal deliveryRandomized trialsOpen groupElectronic fetal heart rate monitorMasked groupElectronic fetal heart rate monitoringFetal heart rate patternsUmbilical artery blood pHContinuous electronic fetal monitoringIntrapartum fetal deathFetal heart rate monitoringPrimary study outcomeOperative vaginal deliveryWeeks of gestationHeart rate patternsSignificant differencesFetal heart rate monitorThe Surgical Apgar Score in esophagectomy
Janowak CF, Blasberg JD, Taylor L, Maloney JD, Macke RA. The Surgical Apgar Score in esophagectomy. Journal Of Thoracic And Cardiovascular Surgery 2015, 150: 806-812. PMID: 26234458, DOI: 10.1016/j.jtcvs.2015.07.017.Peer-Reviewed Original ResearchConceptsSurgical Apgar ScoreMajor morbidityApgar scorePostoperative complicationsMultivariate analysisPreoperative patient characteristicsShort-term outcomesBody mass indexStrongest predictorElective esophagectomyTranshiatal techniqueSurgical populationIntraoperative detailsIntraoperative variablesPatient characteristicsDiabetes mellitusPrimary outcomeRetrospective reviewMass indexProspective studyCare modificationsMalignant diseaseRisk factorsUnivariate analysisImproved outcomes
2014
Maternal Race, Demography, and Health Care Disparities Impact Risk for Intraventricular Hemorrhage in Preterm Neonates
Shankaran S, Lin A, Maller-Kesselman J, Zhang H, O'Shea TM, Bada HS, Kaiser JR, Lifton RP, Bauer CR, Ment LR, Study G. Maternal Race, Demography, and Health Care Disparities Impact Risk for Intraventricular Hemorrhage in Preterm Neonates. The Journal Of Pediatrics 2014, 164: 1005-1011.e3. PMID: 24589078, PMCID: PMC4095864, DOI: 10.1016/j.jpeds.2014.01.036.Peer-Reviewed Original ResearchMeSH KeywordsBlack or African AmericanBlack PeopleCase-Control StudiesCerebral HemorrhageFemaleHealthcare DisparitiesHumansInfant, NewbornInfant, PrematureInfant, Premature, DiseasesLogistic ModelsMaleMultivariate AnalysisPregnancyPrenatal CareRisk FactorsSocioeconomic FactorsSwedenUltrasonographyUnited StatesWhite PeopleConceptsIntraventricular hemorrhageWhite infantsGrade 2Multiple gestationsPrenatal visitWhite raceNeonatal intensive care unitAntenatal steroid exposureGestational age infantsBirth weight 500Birth weight rangeIntensive care unitAfrican ancestryMultivariate logistic regressionHigher maternal educationHigh-frequency ventilationHealth care disparitiesAntenatal steroidsApgar scoreCesarean deliveryPreterm neonatesCare unitGestational ageSteroid exposureAge infants
2013
Gene–environment interactions in severe intraventricular hemorrhage of preterm neonates
Ment LR, Ådén U, Lin A, Kwon SH, Choi M, Hallman M, Lifton RP, Zhang H, Bauer CR. Gene–environment interactions in severe intraventricular hemorrhage of preterm neonates. Pediatric Research 2013, 75: 241-250. PMID: 24192699, PMCID: PMC3946468, DOI: 10.1038/pr.2013.195.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsApgar ScoreBlood CoagulationCerebral VentriclesCerebrovascular CirculationCollagen Type IVFactor VGene-Environment InteractionGenetic Predisposition to DiseaseGenetic VariationGestational AgeHumansHypoxia, BrainInfantInfant, PrematureInflammation MediatorsIntracranial HemorrhagesMethylenetetrahydrofolate Reductase (NADPH2)PhenotypePremature BirthPrognosisRisk FactorsConceptsIntraventricular hemorrhageCerebral injuryPreterm neonatesFactor V Leiden geneRisk of IVHEnvironmental triggersSevere intraventricular hemorrhageCerebral blood flowMethylenetetrahydrofolate reductase (MTHFR) variantsUnknown environmental triggersPresence of mutationsPeriventricular infarctionApgar scorePerinatal hypoxiaPreclinical dataFetal environmentGerminal matrixCerebral vasculatureBlood flowT polymorphismGene-environment interactionsMTHFR 677CHemorrhageNeonatesVascular pathwaysFetal isolated short femur in the second trimester and adverse pregnancy outcomes
Özlü T, Ozcan T. Fetal isolated short femur in the second trimester and adverse pregnancy outcomes. Prenatal Diagnosis 2013, 33: 1063-1069. PMID: 23839963, DOI: 10.1002/pd.4197.Peer-Reviewed Original ResearchConceptsLow birth weightAdverse pregnancy outcomesPreterm birthBirth weightPregnancy outcomesFemur lengthShort femurNeonatal intensive care unit admissionLow birth weight infantsRisk of low birth weightIsolated short femurIntensive care unit admissionIncidence of PEMultiple logistic regressionEligible fetusesSingleton pregnanciesApgar scoreGestational ageTrimester ultrasoundMultiple pregnanciesObstetric scanAbdominal circumferenceChromosomal anomaliesUnit admissionDelivery weightMaintained consciousness during witnessed asystole after spinal anesthesia for Cesarean section
Rajput K, Woehlck H, Riess M. Maintained consciousness during witnessed asystole after spinal anesthesia for Cesarean section. F1000Research 2013, 2: 11. DOI: 10.12688/f1000research.2-11.v1.Peer-Reviewed Case Reports and Technical NotesSpinal anesthesiaCesarean sectionSupine positionHeart rateHigh mortalityOnset of asystoleElective cesarean sectionCerebral blood flowRegular sinus rhythmLoss of consciousnessSpontaneous cardiac activityApgar scoreCerebral hypoxiaVenous poolingCardiac arrestEpinephrine administrationHealthy patientsSinus rhythmVenous bloodLower incidenceCerebral vasculatureBlood flowVagal toneChest compressionsResuscitative drugs
2012
Predictors of stunting, wasting and underweight among Tanzanian children born to HIV-infected women
McDonald CM, Kupka R, Manji KP, Okuma J, Bosch RJ, Aboud S, Kisenge R, Spiegelman D, Fawzi WW, Duggan CP. Predictors of stunting, wasting and underweight among Tanzanian children born to HIV-infected women. European Journal Of Clinical Nutrition 2012, 66: 1265-1276. PMID: 23031850, PMCID: PMC3491141, DOI: 10.1038/ejcn.2012.136.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBody HeightBody WeightDouble-Blind MethodEducational StatusFemaleGrowth DisordersHIV InfectionsHumansInfantInfant, Low Birth WeightInfant, NewbornInfant, PrematureInfectious Disease Transmission, VerticalMaleMalnutritionPremature BirthPrevalenceProportional Hazards ModelsReference ValuesSex FactorsSocioeconomic FactorsTanzaniaThinnessWasting SyndromeYoung AdultConceptsBirth weightFirst episodeTanzanian childrenMultivariate Cox proportional hazards methodMaternal educationLow infant birth weightCox proportional hazards methodDevelopment of undernutritionInfant birth weightLow Apgar scoreModifiable risk factorsLow birth weightChild HIV infectionHuman immunodeficiency virusPredictors of stuntingRisk of undernutritionProportional hazards methodsLow maternal educationWeeks of ageMorbidity historiesApgar scoreChild transmissionMedian durationPreterm infantsHIV infection
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