2025
Race Comparisons in Patients With Cardiac Sarcoidosis: Insights From the Cardiac Sarcoidosis Consortium.
Trongtorsak A, De La Rosa Martinez J, Crawford T, Bogun F, Gu X, Purroll E, Ellenbogen K, Chicos A, Roukoz H, Zimetbaum P, Kalbfleisch S, Murgatroyd F, Steckman D, Rosenfeld L, Soejima K, Bhan A, Vedantham V, Dickfeld T, De Lurgio D, Platonov P, Zipse M, Nishiuchi S, Ortman M, Narasimhan C, Patton K, Rosenthal D, Mukerji S, Hoogendoorn J, Zeppenfeld K, Torosoff M, Judson M, Martin K, Madias C, Hermel M, Nour K, Torbey E, Sauer W, Kron J. Race Comparisons in Patients With Cardiac Sarcoidosis: Insights From the Cardiac Sarcoidosis Consortium. Circulation Arrhythmia And Electrophysiology 2025, e013670. PMID: 40557494, DOI: 10.1161/circep.124.013670.Peer-Reviewed Original ResearchLeft ventricular ejection fractionCardiac sarcoidosisVentricular ejection fractionBlack patientsEjection fractionNo significant differenceClinical outcomesPrimary outcomeWhite patientsImplantable cardioverter defibrillator therapyLeft ventricular assist device implantationSignificant differenceVentricular assist device implantationComposite end pointChronic kidney diseaseChronic obstructive pulmonary diseaseAll-Cause MortalityAssist device implantationRates of lungRates of hypertensionObstructive pulmonary diseaseImplantable cardioverter defibrillatorExtracardiac involvementEye involvementHeart transplantationPre‐Diagnosis Alkaline Phosphatase and Antimitochondrial Antibody Positivity Vary by Race/Ethnicity Among Patients With Primary Biliary Cholangitis
Caines A, Lu M, Wu T, Trudeau S, Melkonian C, Gonzalez H, Sahota A, Schmidt M, Daida Y, Bowlus C, Gordon S. Pre‐Diagnosis Alkaline Phosphatase and Antimitochondrial Antibody Positivity Vary by Race/Ethnicity Among Patients With Primary Biliary Cholangitis. Journal Of Gastroenterology And Hepatology 2025 PMID: 40551359, DOI: 10.1111/jgh.17035.Peer-Reviewed Original ResearchPrimary biliary cholangitisAntimitochondrial antibody positivityAntimitochondrial antibodiesYears prior to diagnosisAMA-positiveNHW patientsBiliary cholangitisDiagnosis of primary biliary cholangitisBlack patientsPrimary biliary cholangitis patientsAlkaline phosphatasePositive antimitochondrial antibodyElevated alkaline phosphataseEvaluate racial differencesPre-DiagnosisAsian American Pacific IslanderPBC patientsAAPI patientsPatient groupALP levelsPatientsDiagnosisNHWCholangitisNon-HispanicTrends, disparities, and outcomes of drug-induced pancreatitis in the United States: A nationwide analysis (2016–2020)
Tchoukeu G, Boateng S, Mekontso J, Al-Ajlouni Y, Njei B. Trends, disparities, and outcomes of drug-induced pancreatitis in the United States: A nationwide analysis (2016–2020). Clinics And Research In Hepatology And Gastroenterology 2025, 49: 102641. PMID: 40544992, DOI: 10.1016/j.clinre.2025.102641.Peer-Reviewed Original ResearchDrug-induced pancreatitisAcute kidney injuryKidney injuryEtiology of acute pancreatitisIncreased risk of cardiac arrestHospital chargesNational Inpatient Sample (NIS) databaseRisk of cardiac arrestMean hospital chargesRetrospective studySignificant racial disparitiesAcute pancreatitisAffected patientsCardiac arrestSignificant oddsPrimary outcomeIncreased riskBlack patientsSecondary outcomesCommon comorbiditiesPancreatitisPatientsInpatient mortalityMortality rateLonger LOSRepresentation of Women, Older Adults, and Racial and Ethnic Minoritized Patients in Pivotal Trials for US Food and Drug Administration Novel Oncology Therapeutic Approvals, 2012-2021: Bright Spot Trials and Trends Over Time.
Miller J, Pelletiers W, Gross C, Mello M, Ramachandran R, Schwartz J, Suttiratana S, Varma T, Ross J. Representation of Women, Older Adults, and Racial and Ethnic Minoritized Patients in Pivotal Trials for US Food and Drug Administration Novel Oncology Therapeutic Approvals, 2012-2021: Bright Spot Trials and Trends Over Time. JCO Oncology Practice 2025, op2400563. PMID: 40493876, DOI: 10.1200/op-24-00563.Peer-Reviewed Original ResearchFood and Drug AdministrationOncology therapeuticsLatino patientsBlack patientsTherapeutic approvalsOlder adultsRetrospective cross-sectional studyUS Food and Drug AdministrationTrial characteristicsMinoritized patientsUS patient populationSpot trialsPivotal trialsPatient demographicsPatient populationRepresentative patientsTrial enrollmentUS Census dataDrug AdministrationPatientsStudy of trialsTrialsOncologyWomenClinical trial diversitySWOG S2302, PRAGMATICA-LUNG: A pragmatic trial designed to increase participant representation.
Reckamp K, Redman M, Dragnev K, Khalil M, Henick B, Moon J, Ahmadzai P, LeBlanc M, Carrizosa D, Herbst R, Blanke C, Gray J. SWOG S2302, PRAGMATICA-LUNG: A pragmatic trial designed to increase participant representation. Journal Of Clinical Oncology 2025, 43: 11016-11016. DOI: 10.1200/jco.2025.43.16_suppl.11016.Peer-Reviewed Original ResearchNon-small cell lung cancerAdvanced non-small cell lung cancerStandard of careOverall survivalPD-(L)1Randomized phase III trialPhase II Randomized StudyPlatinum-based therapyTreated with immunotherapyPhase III trialsCell lung cancerYears of ageInhibitor therapyIII trialsStudy drugConcomitant medicationsOS endpointSafety profileToxicity profileAdverse eventsEffective therapyLung cancerBlack patientsReal-world practiceLaboratory assessmentThe impact of race on the association between structural racism and the quality of non-small cell lung cancer (NSCLC).
Gaddy J, Lee D, Herrin J, Yu J, Pollack C, Dean L, Hamid S, Feder S, Canavan M, Soulos P, Gross C. The impact of race on the association between structural racism and the quality of non-small cell lung cancer (NSCLC). Journal Of Clinical Oncology 2025, 43: 1598-1598. DOI: 10.1200/jco.2025.43.16_suppl.1598.Peer-Reviewed Original ResearchPatient raceStructural racismNon-small cell lung cancerBlack patientsWhite patientsTwo-year survivalAppropriate evaluationSurveillance, EpidemiologyMixed effects logistic regression modelsMultivariable mixed effects logistic regression modelsEffects logistic regression modelsRegression modelsLogistic regression modelsLowest quintileHealth careRacial disparitiesRacial inequalityImpact of raceLocal stagingQuintileCell lung cancerMinoritized communitiesInteraction termsAssociationDisparities30 year trends in racial disparities for early stage lung cancer treatment.
Lynch O, Lee D, Soulos P, Yu J, Herrin J, Gross C. 30 year trends in racial disparities for early stage lung cancer treatment. Journal Of Clinical Oncology 2025, 43: 1599-1599. DOI: 10.1200/jco.2025.43.16_suppl.1599.Peer-Reviewed Original ResearchReceipt of curative therapyReceipt of curative treatmentCurative therapyCurative treatmentLung cancer treatmentWhite patientsBlack patientsReceipt of treatmentRacial disparitiesBlack-white differencesStage I-II NSCLCEarly stage lung cancerCancer treatmentStage lung cancerYears prior to diagnosisMedicare beneficiariesMonths of diagnosisRetrospective cohort studyMultivariate logistic regressionAssessed temporal trendsNon-LatinxProbability of treatmentPredictive probability of treatmentSEER-MedicareLung cancerGovernance for anti-racist AI in healthcare: integrating racism-related stress in psychiatric algorithms for Black Americans
Fields C, Black C, Thind J, Jegede O, Aksen D, Rosenblatt M, Assari S, Bellamy C, Anderson E, Holmes A, Scheinost D. Governance for anti-racist AI in healthcare: integrating racism-related stress in psychiatric algorithms for Black Americans. Frontiers In Digital Health 2025, 7: 1492736. PMID: 40444183, PMCID: PMC12119476, DOI: 10.3389/fdgth.2025.1492736.Peer-Reviewed Original ResearchRacism-related stressBlack patientsBlack AmericansClinical algorithmAnti-Black racismHealthcare interventionsAnti-Black biasHealth outcomesHealth policySocioeconomic statusIntervention modelHistory of enslavementPatient outcomesCommunity membersHealthcareGenerational traumaHealthAmerica's historyBlack researchersSources of varianceClinical practiceEquitable outcomesSocial factorsRacial groupsAI governanceRacial, ethnic, and sex disparities in buprenorphine treatment from emergency departments by discharge diagnosis
Chhabra N, Smith D, Parde N, Hsing‐Smith N, Bianco J, Taylor R, D'Onofrio G, Karnik N. Racial, ethnic, and sex disparities in buprenorphine treatment from emergency departments by discharge diagnosis. Academic Emergency Medicine 2025 PMID: 40277252, DOI: 10.1111/acem.70035.Peer-Reviewed Original ResearchOpioid withdrawalPrescribing of buprenorphineEmergency departmentSex disparitiesBlack patientsDischarge diagnosisEffects of opioidsOpioid overdoseED-initiated buprenorphineOpioid-related ED encountersMultivariate logistic regressionReceipt of buprenorphineFemale patientsOpioid complicationsBuprenorphine treatmentWhite patientsCross-sectional analysisOpioid-related encountersOpioidAmerican patientsAdjusted oddsDecreased oddsBuprenorphinePatientsSubtype analysisA Multilevel Investigation of Potential Inequities in the Volume of Mental Health Care Received by Black Veterans Health Administration Patients
Boden M, Katz I, Harris A, Hoff R, Trafton J. A Multilevel Investigation of Potential Inequities in the Volume of Mental Health Care Received by Black Veterans Health Administration Patients. Psychological Services 2025 PMID: 40244979, DOI: 10.1037/ser0000936.Peer-Reviewed Original ResearchVeterans Health AdministrationMental health careHealth careNon-black patientsBlack patientsPotential inequalitiesVeterans Health Administration patientsIncrease health equityMental health patientsCross-sectional retrospective observational studyMental health conditionsMental health treatmentNegative binomial regressionHealth equityStaffing ratiosHealth patientsFacility-level analysisVHA patientsHealth treatmentHealth AdministrationHigher overall volumeHealth conditionsBinomial regressionLess careCareThe role of regional and practice trial sites in nonrepresentative randomized cancer trial enrollment
Shah S, Manz C, Balthis B, Raman H, Abaluck J, Keating N, Agha L. The role of regional and practice trial sites in nonrepresentative randomized cancer trial enrollment. Journal Of The National Cancer Institute 2025, djaf071. PMID: 40108483, DOI: 10.1093/jnci/djaf071.Peer-Reviewed Original ResearchSEER-Medicare cohortBlack patientsCohort of peoplePrevalence of ageDrug trial participationCancer trialsPatient-level dataRural patientsTrial recruitmentRural residentsSEER-MedicareTrial participantsTrial enrollmentRepresentative trialsEnrolling patientsRenal cancerUnder-enrolledCancer treatmentPatientsEnrollmentPracticeTrialsCancerTrial sitesDisparitiesRacial and ethnic disparities in aortic stenosis within a universal healthcare system characterized by natural language processing for targeted intervention
Biswas D, Wu J, Brown S, Bharucha A, Fairhurst N, Kaye G, Jones K, Copeland F, O’Donnell B, Kyle D, Searle T, Pareek N, Dworakowski R, Papachristidis A, Melikian N, Wendler O, Deshpande R, Baghai M, Galloway J, Teo J, Dobson R, Byrne J, MacCarthy P, Shah A, Eskandari M, O’Gallagher K. Racial and ethnic disparities in aortic stenosis within a universal healthcare system characterized by natural language processing for targeted intervention. European Heart Journal - Digital Health 2025, 6: 392-403. PMID: 40395418, PMCID: PMC12088714, DOI: 10.1093/ehjdh/ztaf018.Peer-Reviewed Original ResearchSurgical aortic valve replacementTranscatheter aortic valve implantationAortic stenosisBlack patientsWhite patientsSevere ASEthnic disparitiesSurgical aortic valve replacement proceduresAS managementAortic valve replacementRetrospective cohort studySocioeconomic statusAll-Cause MortalityAortic valve implantationHealthcare systemAS severityValve replacementUniversal healthcare systemValvular interventionsSelf-reported raceCohort studyValve implantationSymptomatic casesMultivariate analysisPrimary outcomeMediators of Racial Inequities in Non‐Small Cell Lung Cancer Care
Hamid S, Lee D, Herrin J, Yu J, Pollack C, Dean L, Gaddy J, Oladele C, Feder S, Canavan M, Nunez-Smith M, Soulos P, Gross C. Mediators of Racial Inequities in Non‐Small Cell Lung Cancer Care. Cancer Medicine 2025, 14: e70757. PMID: 40052387, PMCID: PMC11886416, DOI: 10.1002/cam4.70757.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancer carePhase of careSocioeconomic statusNon-small cell lung cancerIndividual-level socioeconomic statusNeighborhood-level socioeconomic statusMedicare-Medicaid dual eligibilityWhite patientsHealth care accessLung cancer careNon-Hispanic blacksIndirect effects of mediatorsDiagnosis stageStage-appropriate treatmentTwo-year survivalCancer careCare accessEffects of raceOptimal careDual eligiblesCareStructural racismRacial inequalityBlack patientsInadequate evaluationHistorical Perspectives on Hair Care and Common Styling Practices in Black Women.
Wong N, Williams K, Tolliver S, Potts G. Historical Perspectives on Hair Care and Common Styling Practices in Black Women. Cutis 2025, 115: 95-98. PMID: 40315468, DOI: 10.12788/cutis.1183.Peer-Reviewed Original ResearchTelemedicine Use and Hypertension Control in an Urban Community Health Center Cohort
Molina F, Westvold S, Soulos P, Brockman A, Alcaraz E, Oldfield B. Telemedicine Use and Hypertension Control in an Urban Community Health Center Cohort. Journal Of General Internal Medicine 2025, 40: 1519-1526. PMID: 39920430, PMCID: PMC12052640, DOI: 10.1007/s11606-025-09393-x.Peer-Reviewed Original ResearchBlood pressure <Safety-net primary care settingBlood pressure controlMultisite community health centerHypertension controlMain MeasuresThe primary outcomeBP controlAssociated with blood pressure controlChronic disease managementSocial deprivation indexAssociated with lower oddsCommunity health centersPrimary care settingSafety-net populationMeasuresThe primary outcomeBlack patientsMixed-effects logistic regression modelsIn-Person VisitsPersistent racial disparitiesAssociated with blood pressureSystolic blood pressure <Logistic regression modelsDeprivation indexDiastolic blood pressure <High deprivation
2024
Racial Disparities in Perioperative Outcomes for Patients With Head and Neck Cancer
Fereydooni S, Valdez C, Williams L, Verma A, Judson B. Racial Disparities in Perioperative Outcomes for Patients With Head and Neck Cancer. Head & Neck 2024, 47: 1336-1344. PMID: 39713894, DOI: 10.1002/hed.28034.Peer-Reviewed Original ResearchHead and neck cancerBlack patientsPerioperative outcomesPerioperative complicationsNeck cancerSocial determinants of health variablesNational Surgical Quality Improvement Program databaseRacial disparitiesHead and neck cancer surgeryQuality Improvement Program databaseComprehensive surgical databaseDrainage of abscessesAlaskan Native patientsFramework of healthAssociation of raceEvidence of racial disparitiesMultivariate logistic regressionExtended hospital stayNon-home dischargePostoperative hemorrhageSurgical databasePostoperative transfusionReoperation rateSurgical debridementSocial determinantsUnveiling Inequities: Racial Disparities in Risk-Reducing Mastectomy for Breast Cancer Prevention
Knoedler S, Diatta F, Klimitz F, Noel O, Kempa J, Obed D, Song S, Mayer H, Kim B, Kauke-Navarro M, Pomahac B, Butler P. Unveiling Inequities: Racial Disparities in Risk-Reducing Mastectomy for Breast Cancer Prevention. Clinical Breast Cancer 2024, 25: e312-e320. PMID: 39743397, DOI: 10.1016/j.clbc.2024.12.004.Peer-Reviewed Original ResearchRisk-reducing mastectomyMinority patientsRacial minority patientsBreast cancer preventionRacial disparitiesQuality Improvement ProgramNational Surgical Quality Improvement ProgramSurgical Quality Improvement ProgramWhite patientsCancer preventionStudy investigates racial disparitiesBreast cancer riskEquitable healthcare accessBlack patientsRates of obesityPrevalence of obesityBlack/African American womenImprovement programsPostoperative outcomesOutpatient surgeryAmerican College of Surgeons National Surgical Quality Improvement ProgramSurgeons National Surgical Quality Improvement ProgramHealth equityBreast cancer treatmentHealthcare accessRacial and Ethnic Disparities in the Use and Outcomes With WATCHMAN FLX: A SURPASS Analysis of the NCDR Left Atrial Appendage Occlusion Registry
Alli O, Garg J, Boursiquot B, Kapadia S, Yeh R, Price M, Piccini J, Nair D, Hsu J, Gibson D, Allocco D, Christen T, Sutton B, Freeman J. Racial and Ethnic Disparities in the Use and Outcomes With WATCHMAN FLX: A SURPASS Analysis of the NCDR Left Atrial Appendage Occlusion Registry. Journal Of The American Heart Association 2024, 13: e036406. PMID: 39575715, PMCID: PMC11681556, DOI: 10.1161/jaha.124.036406.Peer-Reviewed Original ResearchLeft atrial appendage occlusionWatchman FLX implantationBlack patientsHispanic patientsOral anticoagulantsProcedural successRates of 1-year deathWhite patientsAlternative to oral anticoagulationRate of procedural successEthnic minority groupsEthnic minority individualsRate of deathSignificant bleedingWatchman FLXMinority individualsAppendage occlusionAntiplatelet therapyBaseline characteristicsAtrial fibrillationAnalyses assessed differencesMinority groupsPatientsStroke preventionBleedingSurvival of Multiple Myeloma Patients in Epic Cosmos Confounded By Death Reporting
Hofmeister C, Zhang M, Gupta V, Joseph N, Kaufman J, Nooka A, Dhodapkar M, Lonial S, Sborov D. Survival of Multiple Myeloma Patients in Epic Cosmos Confounded By Death Reporting. Blood 2024, 144: 5152-5152. DOI: 10.1182/blood-2024-202100.Peer-Reviewed Original ResearchNon-Hispanic blacksNon-Hispanic whitesSurveillance Epidemiology and End ResultsNational Cancer InstituteWhite patientsBlack menBlack patientsAvailability of diagnosisWhite menStudy start dateEncounter dateSEER dataFace-to-faceHealth systemMultiple myeloma patientsMyeloma patientsOutpatient encountersDeath reportingAge decileSocial Vulnerability IndexWhite womenMatched control groupBlack womenMedian survivalPatient recordsImpact of Self-Identified Race on Outcomes in Newly Diagnosed Multiple Myeloma (NDMM) Patients Receiving Induction Therapy with Daratumumab, Lenalidomide, Bortezomib and Dexamethasone (D-RVd)
Joseph N, Gupta S, Kaufman J, Dicamillo S, Roberts D, Gupta V, Hofmeister C, Dhodapkar M, Lonial S, Nooka A. Impact of Self-Identified Race on Outcomes in Newly Diagnosed Multiple Myeloma (NDMM) Patients Receiving Induction Therapy with Daratumumab, Lenalidomide, Bortezomib and Dexamethasone (D-RVd). Blood 2024, 144: 7870-7870. DOI: 10.1182/blood-2024-211988.Peer-Reviewed Original ResearchNewly diagnosed myelomaD-RVdBlack patientsStatistically significant differenceInduction therapyR-ISSOverall survivalMedian ageInternational Myeloma Working Group Uniform Response CriteriaWhite patientsImproved depth of responsePresence of extramedullary diseaseNewly diagnosed multiple myelomaResponse rateMedian overall survivalR-ISS-3Effective induction regimenHigh-risk featuresStem cell transplantationDepth of responseSignificant differenceClinical trial findingsStandard of careHigh-risk classificationMedian PFS
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