2025
Psychological Aspects of Wearable Health Technologies in Patients with Cardiovascular Disease: A Literature Review and Call to Action
Gaffey A, Hooker S, Lampert R, Gehi A, Rosman L. Psychological Aspects of Wearable Health Technologies in Patients with Cardiovascular Disease: A Literature Review and Call to Action. Current Cardiology Reports 2025, 27: 92. PMID: 40478308, DOI: 10.1007/s11886-025-02234-7.Peer-Reviewed Original ResearchConceptsWearable health technologiesMental healthCardiovascular diseaseHealth technologiesCardiovascular disease self-managementPatients' mental healthAdverse psychological reactionsQuality of lifeProvider burdenHealthy behaviorsHealthcare providersHealthcare utilizationSelf-ManagementWell-designed prospective studiesCVD managementHealth metricsHealthcare systemHigh-risk groupLifestyle modificationConsumer wearablesImplementation of wearablesPatient outcomesHealthcarePsychological reactionsPsychological effectsProfiling DNA damage response in ATM/BRCA2 carriers to inform hereditary cancer risk.
Dedousis D, Hasan A, Patel K, Czyzewicz P, Devarajan K, Hall M, Daly M, Arora S. Profiling DNA damage response in ATM/BRCA2 carriers to inform hereditary cancer risk. Journal Of Clinical Oncology 2025, 43: 10574-10574. DOI: 10.1200/jco.2025.43.16_suppl.10574.Peer-Reviewed Original ResearchGermline pathogenic variantsCancer-free controlsPeripheral blood monocytesSignificant cut-pointsCRC casesDNA damage responseCut-pointsHereditary cancer riskBenjamini-Hochberg false discovery rate methodTwo-sided Mann-Whitney testHigh-risk familiesSporadic colorectal cancerPreliminary analysis of patientsDiagnosis of cancerAnalysis of patientsHigh-risk populationFalse discovery rate methodCancer riskHigh-risk groupNegative regulator of p53Age-matched controlsDNA repair genesDamage responseMann-Whitney testNon-carrier controlsThe Five-Item Modified Frailty Index Predicts Adverse Surgical Outcomes in Patients Undergoing Mastectomy
Chiarella L, Huelsboemer L, Diatta F, Klimitz F, Kammien A, Kochen A, Boroumand S, Allam O, Kauke-Navarro M, Pomahac B. The Five-Item Modified Frailty Index Predicts Adverse Surgical Outcomes in Patients Undergoing Mastectomy. Annals Of Surgical Oncology 2025, 32: 4829-4837. PMID: 40342005, DOI: 10.1245/s10434-025-17105-2.Peer-Reviewed Original ResearchConceptsHigh-risk patientsMFI-5Surgical complicationsFrail patientsPredicting adverse surgical outcomesNational Surgical Quality Improvement Program dataIncreased risk of complicationsQuality Improvement Program dataMethodsThis retrospective cohort studyPredicting surgical complicationsDependent functional statusHigher Body Mass IndexAdverse surgical outcomesOdds of complicationsRetrospective cohort studyAcute kidney failureRisk of complicationsAdult female patientsCongestive heart failurePostoperative complication riskAdjusted multivariable logistic regressionBody mass indexChronic obstructive pulmonary diseaseHigh-risk groupMultivariate logistic regressionForecasting optimal treatments in relapsed/refractory mature T‐ and NK‐cell lymphomas: A global PETAL Consortium study
Sorial M, Han J, Koh M, Boussi L, Li S, Duan R, Lu J, Lei M, MacVicar C, Freydman J, Malespini J, Aniagboso K, McCabe S, Peng L, Singh S, Iwasaki M, Eche‐Ugwu I, Gabler J, Turizo M, Garg A, Disciullo A, Chopra K, Ford J, Lenart A, Nwodo E, Barnes J, Koh M, Miranda E, Chiattone C, Stuver R, Merrill M, Jacobsen E, Manni M, Civallero M, Skrypets T, Lymboussaki A, Federico M, Kim Y, Kim J, Cho J, Eipe T, Shet T, Epari S, Shetty A, Saha S, Jain H, Sengar M, Van Der Weyden C, Prince H, Hamouche R, Muradashvili T, Foss F, Gentilini M, Casadei B, Zinzani P, Okatani T, Yoshida N, Yoon S, Kim W, Panchoo G, Mohamed Z, Verburgh E, Alturas J, Al‐Mansour M, Cabrera M, Ku A, Bhagat G, Ma H, Sawas A, Kariya K, Bhanushali F, Meharwal A, Mistry D, Kosovsky M, Yeterian M, O'Connor O, Marchi E, Shen C, Shah D, Jain S. Forecasting optimal treatments in relapsed/refractory mature T‐ and NK‐cell lymphomas: A global PETAL Consortium study. British Journal Of Haematology 2025, 206: 1664-1677. PMID: 40310502, PMCID: PMC12167149, DOI: 10.1111/bjh.20063.Peer-Reviewed Original ResearchConceptsT-cell lymphomaCytotoxic chemotherapySmall molecule inhibitorsEpigenetic modifiersAngioimmunoblastic T-cell lymphomaPrimary refractory diseaseNK-cell lymphomasHigh-risk groupTransplant consolidationOverall survivalRefractory diseaseNK cellsPrognostic indexT cellsIdeal therapyMature TOptimal treatmentLymphomaGlobal cohortTreatment sequenceMolecule inhibitorsPatientsThird lineConsortium studyTreatmentLong‐Term Outcomes of Peripheral Artery Disease in Veterans: Analysis of the Peripheral Artery Disease Long‐Term Survival Study (PEARLS)
Girotra S, Li Q, Vaughan‐Sarrazin M, Lund B, Al‐Garadi M, Beckman J, Nathani R, Hoffman R, Chan P, Banerjee S, Tsai S, Kumbhani D, Minniefield‐Young N, Smolderen K, Arya S, Nguyen C, Matheny M, Gobbel G. Long‐Term Outcomes of Peripheral Artery Disease in Veterans: Analysis of the Peripheral Artery Disease Long‐Term Survival Study (PEARLS). Journal Of The American Heart Association 2025, 14: e038403. PMID: 40118806, PMCID: PMC12132885, DOI: 10.1161/jaha.124.038403.Peer-Reviewed Original ResearchConceptsVeterans Health AdministrationPeripheral arterial diseaseHealth AdministrationIntegrated health systemOutcomes of peripheral artery diseaseDiagnosis of peripheral arterial diseaseToe-brachial index valuesPrevalence of hypertensionLimb eventsChronic obstructive pulmonary diseaseAnkle-brachial indexImprove careHealth systemObstructive pulmonary diseaseCardiovascular eventsHigh-risk groupNational registryArtery diseaseVeteransIncidence of cardiovascular eventsRegistryIncidence of deathPulmonary diseasePatient yearsStudy end pointAdolescent health behavior profiles and associations with mental health in a longitudinal study.
Kidwell K, Brock R, Tomaso C, Phillips E, James T, Yaroch A, Hill J, Nelson J, Huang T, Mason W, Espy K, Nelson T. Adolescent health behavior profiles and associations with mental health in a longitudinal study. Journal Of Health Psychology 2025, 13591053251314328. PMID: 39887976, DOI: 10.1177/13591053251314328.Peer-Reviewed Original ResearchAssociated with mental healthHealth behavior profilesMental healthBehavioral profileSubstance useLow fruit/vegetable intakeHealth behavior patternsMental health symptomsMinimal substance useAdolescent health behaviorsFruit/vegetable intakePhysical activityHealthy behaviorsHealth behaviorsParental psychopathologyHealth symptomsHigh-risk groupAverage sleepE-cigarettesAssessment pointsIntervention effortsSleep durationHealthLongitudinal studyProfile 2Prevalence of Moral Injury in Nationally Representative Samples of Combat Veterans, Healthcare Workers, and First Responders
Maguen S, Griffin B, Pietrzak R, McLean C, Hamblen J, Norman S. Prevalence of Moral Injury in Nationally Representative Samples of Combat Veterans, Healthcare Workers, and First Responders. Journal Of General Internal Medicine 2025, 1-7. PMID: 39881119, DOI: 10.1007/s11606-024-09337-x.Peer-Reviewed Original ResearchNationally Representative SampleHealthcare workersRepresentative sampleMoral injuryDesignCross-sectional surveyPrevalence of moral injuryFirst respondersExposure to PMIEsMoral injury symptomsCombat veteransHigh-risk populationHigh-risk groupInjury eventsInjury exposureHealthcareVeteransWell-beingOccupational differencesRespondentsPMIEsPrevalenceWorkersComplex decisionsClinicInjuryBiomarker Panels for Discriminating Risk of CKD Progression in Children
Greenberg J, Abraham A, Xu Y, Schelling J, Coca S, Schrauben S, Wilson F, Waikar S, Vasan R, Gutiérrez O, Shlipak M, Ix J, Warady B, Kimmel P, Bonventre J, Parikh C, Denburg M, Furth S. Biomarker Panels for Discriminating Risk of CKD Progression in Children. Journal Of The American Society Of Nephrology 2025, 36: 1105-1115. PMID: 39820177, PMCID: PMC12147970, DOI: 10.1681/asn.0000000602.Peer-Reviewed Original ResearchPlasma KIM-1CKD progressionKIM-1Alpha 1-microglobulinUrine albumin/creatinineBaseline urine protein-to-creatinine ratiosBiomarker panelRisk factorsRisk of CKD progressionAssociated with CKD progressionUrine alpha-1-microglobulinRisk group classificationProtein-to-creatinine ratioUrine protein-to-creatinine ratioClinical risk factorsChildren 6 monthsHigh-risk groupUrine KIM-1Clinically relevant biomarkersConventional risk factorsCombination of biomarkersTubular healthBaseline eGFRMedian ageEGFR decline
2024
Incidence and antecedents of emergent suicidal ideation and behavior among Veterans with serious mental illness receiving intensive case management
Browne J, Mohamed S. Incidence and antecedents of emergent suicidal ideation and behavior among Veterans with serious mental illness receiving intensive case management. Journal Of Psychiatric Research 2024, 181: 607-613. PMID: 39740616, DOI: 10.1016/j.jpsychires.2024.12.018.Peer-Reviewed Original ResearchConceptsEmergent suicidal ideationSuicidal ideationMental illnessBehavior groupCommunity-based treatment programsAffective disorder diagnosesSix-month follow-up assessmentFollow-up assessmentService useSubjective distressDisorder diagnosisLifetime hospitalizationsQuality of lifeIdeationProgram evaluation dataTreatment programsVeteransVeterans Health AdministrationBaseline quality of lifePrimary study aimSix-month incidenceBehavioral patternsHealth AdministrationIllnessHigh-risk groupA multimodal Neuroimaging-Based risk score for mild cognitive impairment
Zendehrouh E, Sendi M, Abrol A, Batta I, Hassanzadeh R, Calhoun V. A multimodal Neuroimaging-Based risk score for mild cognitive impairment. NeuroImage Clinical 2024, 45: 103719. PMID: 39637673, PMCID: PMC11664180, DOI: 10.1016/j.nicl.2024.103719.Peer-Reviewed Original ResearchMild cognitive impairment riskMild cognitive impairmentMild cognitive impairment groupRisk of mild cognitive impairmentRisk scoreUK Biobank participantsFunctional network connectivityCognitive impairmentPrecursor to ADSignificant cognitive declineBiobank participantsUK BiobankMild cognitive impairment individualsGenetic risk factorsAlzheimer's diseaseFunctional MRIHigh-risk groupStructural MRIAD riskRisk factorsCognitive declineFeatures of CNGray matterDifferentiate CNParticipantsMitochondrial heteroplasmy improves risk prediction for myeloid neoplasms
Hong Y, Pasca S, Shi W, Puiu D, Lake N, Lek M, Ru M, Grove M, Prizment A, Joshu C, Platz E, Guallar E, Arking D, Gondek L. Mitochondrial heteroplasmy improves risk prediction for myeloid neoplasms. Nature Communications 2024, 15: 10133. PMID: 39578475, PMCID: PMC11584845, DOI: 10.1038/s41467-024-54443-3.Peer-Reviewed Original ResearchConceptsClonal hematopoiesis of indeterminate potentialClonal hematopoiesisVariant allele fractionHeteroplasmic variantsIndeterminate potentialMyeloid neoplasmsHeteroplasmyMultiple mutationsAllele fractionMutationsHigh-risk groupPathogenic risk factorsMarkersRisk score modelDeleteriousnessSpliceosomeHematologic malignanciesRisk stratificationNeoplasm developmentNeoplasmsNeoplasm incidenceRisk factorsVariantsHormone Receptor-Positive HER2-Negative/MammaPrint High-2 Breast Cancers Closely Resemble Triple-Negative Breast Cancers.
Rios-Hoyo A, Xiong K, Dai J, Yau C, Marczyk M, Garcia-Milian R, Wolf D, Huppert L, Nanda R, Hirst G, Cobain E, van 't Veer L, Esserman L, Pusztai L. Hormone Receptor-Positive HER2-Negative/MammaPrint High-2 Breast Cancers Closely Resemble Triple-Negative Breast Cancers. Clinical Cancer Research 2024, 31: 403-413. PMID: 39561272, PMCID: PMC11747811, DOI: 10.1158/1078-0432.ccr-24-1553.Peer-Reviewed Original ResearchPathological complete responseEvent-free survivalBreast cancerHER2 negative breast cancerHormone receptor-positive/HER2-negativePathologic complete response ratePrognostic risk categoriesTN breast cancerNegative breast cancerGene set analysisExpression of cell cycleGene expression dataLow-risk subgroupsHigh-risk groupMammaPrint assayNeoadjuvant trialsComplete responseER statusResidual cancerPrognostic groupsClinical featuresI-SPY2Prognostic assaysExpression dataTreatment strategiesRADT-12. DERIVING IMAGING BIOMARKERS FOR PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA USING DEEP LEARNING
Zhu J, Hager T, Chadha S, Sritharan D, Weiss D, Hossain S, Osenberg K, Moore N, Aneja S. RADT-12. DERIVING IMAGING BIOMARKERS FOR PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA USING DEEP LEARNING. Neuro-Oncology 2024, 26: viii74-viii74. PMCID: PMC11553274, DOI: 10.1093/neuonc/noae165.0296.Peer-Reviewed Original ResearchPrimary central nervous system lymphomaWhole-brain radiotherapyTreated with chemotherapyOverall survivalHigh-risk groupPatient phenotypesCentral nervous system lymphomaPCNSL treatmentRisk of neurocognitive side effectsImaging biomarkersC-statisticOne-year OSTwo-year OSNervous system lymphomaAssociated with improved outcomesLog-rank testNeurocognitive side effectsTime-dependent AUCBrain radiotherapySystem lymphomaTumor volumeTumor sizeRisk stratificationAnalyses assessed differencesSub-analysisClinically relevant findings on 24-h head CT after acute stroke therapy: The 24-h CT score
Zhang B, King A, Voetsch B, Silverman S, Schwamm L, Ji X, Singhal A. Clinically relevant findings on 24-h head CT after acute stroke therapy: The 24-h CT score. International Journal Of Stroke 2024, 20: 226-234. PMID: 39324561, DOI: 10.1177/17474930241289992.Peer-Reviewed Original ResearchCT scoreCT findingsHead CTClinically relevant findingsFollow-up head CTRoutine head computed tomographyHead CT findingsHead Computed TomographyConsecutive acute ischemic stroke patientsBlood pressure goalsAcute ischemic stroke patientsLow-risk groupMedium-risk groupAdministration of mannitolHigh-risk groupMultivariate logistic regressionAcute stroke therapyComprehensive stroke centerIschemic stroke patientsBlood glucose levelsCT abnormalitiesAntithrombotic treatmentRelevant findingsHypertonic salineRetrospective studyTransactional sex and its associated factors among gay, bisexual and other men who have sex with men in Nepal
Sujan M, Paudel K, Gautam K, Khati A, Wickersham J, Dhakal M, Ha T, Shrestha R. Transactional sex and its associated factors among gay, bisexual and other men who have sex with men in Nepal. Sexual Health 2024, 21 PMID: 39388431, DOI: 10.1071/sh24178.Peer-Reviewed Original ResearchConceptsTransactional sexPrevalence of transactional sexFactors associated with transactional sexExchange of sexReduce transactional sexPolice detentionMental health challengesEconomic vulnerabilityTransgender womenFinancial dependenceGBMSMCondomless sexSubstance useAssociated with adverse health outcomesNepalParticipants' sociodemographic characteristics,Cross-sectional surveyMultivariate logistic regression analysisAdverse health outcomesAge of participantsHealth outcomesSexually transmitted infectionsHigh-risk groupSociodemographic characteristicsLogistic regression analysisPersonal and Social‐Built Environmental Factors of Glucose Variability Among Multiethnic Groups of Adults With Type 2 Diabetes: Research Protocol Using Ecological Momentary Assessment, Continuous Glucose Monitoring, and Actigraphy
Nam S, Jeon S, Ash G, Weinzimer S, Dunton G, Parekh N, Grey M, Chen K, Lee M, Sajdlowska A, Whittemore R. Personal and Social‐Built Environmental Factors of Glucose Variability Among Multiethnic Groups of Adults With Type 2 Diabetes: Research Protocol Using Ecological Momentary Assessment, Continuous Glucose Monitoring, and Actigraphy. Research In Nursing & Health 2024, 47: 608-619. PMID: 39243147, PMCID: PMC11934073, DOI: 10.1002/nur.22420.Peer-Reviewed Original ResearchEmotional Well-BeingType 2 diabetesImprove diabetes outcomesDietary recall dataWell-beingSelf-report toolMultilevel risk factorsEcological momentary assessmentLifestyle behaviorsOnline video callsContinuous glucose monitoringPhysical activityDiabetes outcomesGroup of adultsLifestyle factorsJust-in-time interventionsBaseline surveyDiverse adultsDiabetes InterventionsHigh-risk groupRecall dataMomentary assessmentActigraphy deviceStructural equation modelingGlucose monitoringArtificial Intelligence–Enhanced Risk Stratification of Cancer Therapeutics–Related Cardiac Dysfunction Using Electrocardiographic Images
Oikonomou E, Sangha V, Dhingra L, Aminorroaya A, Coppi A, Krumholz H, Baldassarre L, Khera R. Artificial Intelligence–Enhanced Risk Stratification of Cancer Therapeutics–Related Cardiac Dysfunction Using Electrocardiographic Images. Circulation Cardiovascular Quality And Outcomes 2024, 18: e011504. PMID: 39221857, PMCID: PMC11745701, DOI: 10.1161/circoutcomes.124.011504.Peer-Reviewed Original ResearchCancer therapeutics-related cardiac dysfunctionGlobal longitudinal strainLeft ventricular systolic dysfunctionCardiac dysfunctionBreast cancerNon-Hodgkin lymphoma therapyNon-Hodgkin's lymphomaVentricular systolic dysfunctionAssociated with worse global longitudinal strainRisk stratification strategiesHigh-risk groupMonths post-treatmentPost Hoc AnalysisElectrocardiographic (ECGTrastuzumab exposureLymphoma therapySystolic dysfunctionAI-ECGBefore treatmentRisk biomarkersLongitudinal strainLow riskStratification strategiesHigher incidencePositive screenRisk of new‐onset diabetes and efficacy of pharmacological weight loss therapy
Moura F, Bellavia A, Berg D, Melloni G, Feinberg M, Leiter L, Bohula E, Morrow D, Scirica B, Wiviott S, Sabatine M. Risk of new‐onset diabetes and efficacy of pharmacological weight loss therapy. Diabetes Obesity And Metabolism 2024, 26: 4441-4449. PMID: 39056220, PMCID: PMC11410501, DOI: 10.1111/dom.15798.Peer-Reviewed Original ResearchNew-onset diabetesRisk of new-onset diabetesClinical risk modelWeight loss therapyRisk groupsWeight loss pharmacotherapyMultivariate Cox regressionStable cardiovascular patientsTherapeutic decision makingAbsolute risk reductionHigh-risk groupType 2 diabetesIndependent predictorsValidation cohortFollow-upPersonalized patient careCox regressionHazard ratioPrimary outcomeRisk modelHigh riskInterquartile rangePatientsDiabetesCardiovascular patientsPrepare Romania: study protocol for a randomized controlled trial of an intervention to promote pre-exposure prophylaxis adherence and persistence among gay, bisexual, and other men who have sex with men
Lelutiu-Weinberger C, Filimon M, Zavodszky A, Lixandru M, Hanu L, Fierbinteanu C, Patrascu R, Streinu-Cercel A, Luculescu S, Bora M, Filipescu I, Jianu C, Heightow-Weidman L, Rochelle A, Yi B, Buckner N, Golub S, van Dyk I, Burger J, Li F, Pachankis J. Prepare Romania: study protocol for a randomized controlled trial of an intervention to promote pre-exposure prophylaxis adherence and persistence among gay, bisexual, and other men who have sex with men. Trials 2024, 25: 470. PMID: 38987812, PMCID: PMC11238350, DOI: 10.1186/s13063-024-08313-4.Peer-Reviewed Original ResearchConceptsGBMSM livingPrEP adherenceRandomized controlled trial designMobile health interventionsRollout of PrEPMonths post-randomizationPre-exposure prophylaxisPre-exposure prophylaxis adherenceSelf-report surveyRandomized Controlled TrialsPromotion interventionsPrescribed PrEPEfficacy of toolsHealth interventionsNational rolloutHealth systemPrEP rolloutDiscussionThe knowledgeIntervention efficacyEffectiveness trialBlood spot testingPost-randomizationHigh-risk groupHIV transmissionDried blood spot testingReview of the cost-effectiveness of surveillance for hereditary pancreatic cancer
Wang L, Levinson R, Mezzacappa C, Katona B. Review of the cost-effectiveness of surveillance for hereditary pancreatic cancer. Familial Cancer 2024, 23: 351-360. PMID: 38795221, PMCID: PMC11255025, DOI: 10.1007/s10689-024-00392-1.Peer-Reviewed Original ResearchHigh-risk individualsHereditary pancreatic cancerSusceptibility to pancreatic cancerPancreatic cancer riskFamily history of PCSurveillance strategiesPancreatic cancerCost-effectiveness of surveillanceHistory of PCCost-effectiveness studiesCost-effectiveCancer riskCost-effectiveness analysisPancreatic surveillanceHigh-risk groupOptimal surveillance strategyFamily historyNew-onset diabetesRisk individualsSporadic PCHealth benefitsPotential health benefitsPC diagnosisSub-groupsSurveillance
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply