2025
Implementation of Team Communication and Nurse Feedback to Reduce Cesarean Rates
Suess J, Vandyck R, Telfer M. Implementation of Team Communication and Nurse Feedback to Reduce Cesarean Rates. Journal Of Obstetric Gynecologic & Neonatal Nursing 2025 PMID: 40840535, DOI: 10.1016/j.jogn.2025.07.005.Peer-Reviewed Original ResearchCesarean rateClinical teamPlan-Do-Study-Act cyclesPlan-Do-Study-ActLower cesarean ratesInterprofessional clinical teamsQuality improvement initiativesMain Outcome Measure(sLow-risk pregnanciesNurse midwivesNurse feedbackNursing practicePhysiological birthRate of complianceCesarean birthMaternity unitsResident physiciansVertex presentationClinical auditOutcome Measure(sEligible birthsImprovement initiativesNursesEpic reportNulliparous womenAssociation between Induction Start Time and Labor Duration in Nulliparous Women Undergoing Elective Induction of Labor
Facco F, MacPherson C, Reddy U, Tita A, Silver R, El-Sayed Y, Wapner R, Rouse D, Saade G, Thorp J, Chauhan S, Costantine M, Chien E, Heyborne K, Srinivas S, Swamy G, Grobman W. Association between Induction Start Time and Labor Duration in Nulliparous Women Undergoing Elective Induction of Labor. American Journal Of Perinatology 2025, 42: 1864-1870. PMID: 40015324, PMCID: PMC12315577, DOI: 10.1055/a-2547-4196.Peer-Reviewed Original ResearchInduction of laborCesarean delivery rateLabor durationShorter labor durationElective inductionBishop scoreNulliparous womenLow-risk nulliparous womenElective induction of laborModified Bishop scoreMean labour durationMulti-Center Randomized Controlled TrialDelivery rateBaseline maternal characteristicsBody mass indexFrequency of deliveryARRIVE trialInsurance statusCervical statusMaternal characteristicsSecondary analysisRupture of membranesSpontaneous laborWeeks 0 daysWomen Methods
2024
Pregnancy-Related Factors and Breast Cancer Risk for Women Across a Range of Familial Risk
McDonald J, Liao Y, Knight J, John E, Kurian A, Daly M, Buys S, Huang Y, Frost C, Andrulis I, Colonna S, Friedlander M, Hopper J, Chung W, Genkinger J, MacInnis R, Terry M, Amor D, Andrews L, Antill Y, Balleine R, Beesley J, Bennett I, Bogwitz M, Bodek S, Botes L, Brennan M, Brown M, Buckley M, Burke J, Butow P, Caldon L, Campbell I, Cao M, Chakrabarti A, Chauhan D, Chauhan M, Chenevix-Trench G, Christian A, Cohen P, Colley A, Crook A, Cui J, Courtney E, Cummings M, Dawson S, deFazio A, Delatycki M, Dickson R, Dixon J, Edwards S, Farshid G, Fellows A, Fenton G, Field M, Flanagan J, Fong P, Forrest L, Fox S, French J, Friedlander M, Gaff C, Gattas M, George P, Greening S, Harris M, Hart S, Harraka P, Hayward N, Hopper J, Hoskins C, Hunt C, James P, Jenkins M, Kidd A, Kirk J, Koehler J, Kollias J, Lakhani S, Lawrence M, Lee J, Li S, Lindeman G, Lippey J, Lipton L, Lobb L, Loi S, Mann G, Marsh D, McLachlan S, Meiser B, Milne R, Nightingale S, O'Connell S, O'Sullivan S, Gallego Ortega D, Pachter N, Pang J, Pathak G, Patterson B, Pearn A, Phillips K, Pieper E, Ramus S, Rickard E, Ragunathan A, Robinson B, Saleh M, Skandarajah A, Salisbury E, Saunders C, Saunus J, Savas P, Scott R, Scott C, Sexton A, Shaw J, Shelling A, Srinivasa S, Simpson P, Southey M, Spurdle A, Taylor J, Taylor R, Thorne H, Trainer A, Tucker K, Visvader J, Walker L, Williams R, Winship I, Young M, Zaheed M. Pregnancy-Related Factors and Breast Cancer Risk for Women Across a Range of Familial Risk. JAMA Network Open 2024, 7: e2427441. PMID: 39186276, DOI: 10.1001/jamanetworkopen.2024.27441.Peer-Reviewed Original ResearchConceptsPregnancy-related factorsFull-term pregnancyBC riskNulliparous womenProspective Family Study CohortBreast Cancer Family RegistryBreast cancerBC diagnosisER-negative BCCohort studyHazard ratioCancer Family RegistryBreast cancer riskPersonal history of BCBC family historyCohort study of womenHistory of BCCohort of womenCox proportional hazards regression modelsProportional hazards regression modelsStudy of womenER-negative diseaseFamily RegistryHazards regression modelsScreening guidelinesAssociations between Individual- and Structural-Level Racism and Gestational Age at Birth in the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be
Barcelona V, Chen L, Zhao Y, Samari G, Monk C, McNeil R, Baccarelli A, Wapner R. Associations between Individual- and Structural-Level Racism and Gestational Age at Birth in the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be. Journal Of Urban Health 2024, 101: 682-691. PMID: 38992222, PMCID: PMC11329443, DOI: 10.1007/s11524-024-00889-1.Peer-Reviewed Original ResearchConceptsExperiences of discriminationNulliparous womenMeasures of structural racismSecondary analysis of dataStructural racismNulliparous Pregnancy Outcomes StudyMonitoring Mothers-to-BeAdverse birth outcomesMeasuring structural racismMothers-to-bePregnancy Outcomes StudyGestational ageIndex of ConcentrationBirth outcomesModifiable factorsExperiences of racismSecondary analysisNuMoM2b studyAnalysis of dataSubgroup analysisOutcome studiesU.S. measuresWomenIndividual-Structural-level
2023
Comparing population-based fetal growth standards in a US cohort
Gleason J, Reddy U, Chen Z, Grobman W, Wapner R, Steller J, Simhan H, Scifres C, Blue N, Parry S, Grantz K. Comparing population-based fetal growth standards in a US cohort. American Journal Of Obstetrics And Gynecology 2023, 231: 338.e1-338.e18. PMID: 38151220, PMCID: PMC11196385, DOI: 10.1016/j.ajog.2023.12.034.Peer-Reviewed Original ResearchComposite perinatal morbidityFetal growth standardsPerinatal morbidityNeonatal morbidityWorld Health OrganizationGrowth standardsEunice Kennedy Shriver National InstituteNulliparous Pregnancy Outcomes StudyHighest AUCComposite neonatal morbiditySubsequent neonatal morbidityU.S. clinical centersFetal growth restrictionRisk of morbidityRace/Management of pregnancyPregnancy Outcomes StudyAntenatal monitoringNulliparous womenFetal weightFirst trimesterVisit 2Visit 3US cohortClinical centersCortisol reactivity to a laboratory stressor predicts increases in depressive symptoms in perinatal and nulliparous women during population-level stress
Beech A, Edelman A, Yatziv T, Rutherford H, Joormann J, Gadassi-Polack R. Cortisol reactivity to a laboratory stressor predicts increases in depressive symptoms in perinatal and nulliparous women during population-level stress. Journal Of Affective Disorders 2023, 340: 33-41. PMID: 37499916, PMCID: PMC10529046, DOI: 10.1016/j.jad.2023.07.093.Peer-Reviewed Original ResearchConceptsDepressive symptomsNulliparous womenCortisol reactivityLaboratory stressorHigh-risk groupDepressive symptom questionnairesBiomarkers of riskPsychosocial stress testCurrent depressive symptomsCOVID-19Salivary cortisol samplesPopulation-level stressorGestational weeksSymptom questionnairePerinatal periodNeed of interventionDepression riskCortisol levelsSymptomsCortisol samplesPregnancyWomenCOVID-19 pandemicStress testRiskHypertension in Pregnancy and Adverse Outcomes Among Low-risk Nulliparous Women Expectantly Managed at or After 39 weeks: A Secondary Analysis of a Randomized Controlled Trial
Bartal M, Premkumar A, Rice M, Reddy U, Tita A, Silver R, El-Sayed Y, Wapner R, Rouse D, Saade G, Thorp J, Constantine M, Chien E, Casey B, Srinivas S, Swamy G, Simhan H. Hypertension in Pregnancy and Adverse Outcomes Among Low-risk Nulliparous Women Expectantly Managed at or After 39 weeks: A Secondary Analysis of a Randomized Controlled Trial. Obstetric Anesthesia Digest 2023, 43: 82-82. DOI: 10.1097/01.aoa.0000927856.60760.92.Peer-Reviewed Original ResearchLow-risk patientsLow-risk nulliparous womenHypertensive disordersMaternal morbidityMaternal outcomesNulliparous womenControlled TrialsWeeks' gestationAdverse outcomesLower riskSecondary analysisPregnancyPatientsHDPOutcomesRecent studiesHypertensionMorbidityGestationMortalityPrevalenceTrialsWeeksWomen
2022
Hypertension in pregnancy and adverse outcomes among low‐risk nulliparous women expectantly managed at or after 39 weeks: a secondary analysis of a randomised controlled trial
Bartal M, Premkumar A, Rice M, Reddy U, Tita ATN, Silver RM, El‐Sayed Y, Wapner R, Rouse DJ, Saade GR, Thorp JM, Costantine M, Chien EK, Casey BM, Srinivas SK, Swamy GK, Simhan HN, Health H. Hypertension in pregnancy and adverse outcomes among low‐risk nulliparous women expectantly managed at or after 39 weeks: a secondary analysis of a randomised controlled trial. BJOG An International Journal Of Obstetrics & Gynaecology 2022, 129: 1396-1403. PMID: 34927787, PMCID: PMC9207156, DOI: 10.1111/1471-0528.17059.Peer-Reviewed Original ResearchConceptsAdverse maternal outcomesLow-risk nulliparous womenHypertensive disordersMaternal outcomesSecondary outcomesNulliparous womenAdverse outcomesComposite adverse maternal outcomeIntensive care unit admissionSecondary analysisCare unit admissionSevere neonatal complicationsWeeks of gestationMode of deliveryNulliparous individualsMaternal compositeNeonatal complicationsPerinatal compositePostpartum infectionUnit admissionCaesarean deliveryExpectant managementPlacental abruptionVenous thromboembolismGestational agePericonceptional diet quality predicts glycemic control and gestational diabetes risk in nulliparous women
Milone G, Chung J, Haas D, Silver R, Grobman W, Simhan H, Saade G, Reddy U, Lindsay K. Periconceptional diet quality predicts glycemic control and gestational diabetes risk in nulliparous women. American Journal Of Obstetrics And Gynecology 2022, 226: s46-s47. DOI: 10.1016/j.ajog.2021.11.106.Peer-Reviewed Original Research
2021
Per- and Polyfluoroalkyl Substances and Hormone Levels During the Menopausal Transition
Harlow S, Hood M, Ding N, Mukherjee B, Calafat A, Randolph J, Gold E, Park S. Per- and Polyfluoroalkyl Substances and Hormone Levels During the Menopausal Transition. The Journal Of Clinical Endocrinology & Metabolism 2021, 106: e4427-e4437. PMID: 34181018, PMCID: PMC8677593, DOI: 10.1210/clinem/dgab476.Peer-Reviewed Original ResearchConceptsMidlife womenSex hormone-binding globulinFollicle-stimulating hormoneInverse associationStudy of Women's HealthPositive associationMenopausal transitionBody mass indexReproductive ageWomen's healthSignificant linear trendNo significant associationNulliparous womenLinear mixed modelsSmoking statusYears of ageMass indexHormone-binding globulinMenopausal statusLongitudinal serum concentrationsSignificant associationSerum PFAS concentrationsMidlifeWomenPolyfluoroalkyl substancesDisparities in ART Live Birth and Cumulative Live Birth Outcomes for Hispanic and Asian Women Compared to White Non-Hispanic Women
Kotlyar AM, Simsek B, Seifer DB. Disparities in ART Live Birth and Cumulative Live Birth Outcomes for Hispanic and Asian Women Compared to White Non-Hispanic Women. Journal Of Clinical Medicine 2021, 10: 2615. PMID: 34198545, PMCID: PMC8231797, DOI: 10.3390/jcm10122615.Peer-Reviewed Original ResearchCumulative live birth rateNon-Hispanic womenLive birthsWNH womenAsian womenWhite non-Hispanic womenART live birthsCycles of ARTHistory of endometriosisIndependent prognostic factorLive birth rateReproductive technology outcomesEtiology of infertilityLive birth outcomesMultivariate logistic regressionUse of ICSINumber of embryosNulliparous womenPrognostic factorsBirth outcomesAsian patientsART cyclesART treatmentART statusMember clinicsHigh-Dose Compared With Standard-Dose Oxytocin Regimens to Augment Labor in Nulliparous Women
Son M, Roy A, Stetson BT, Grady NT, Vanecko MC, Bond N, Swanson K, Grobman WA, Miller ES, Peaceman AM. High-Dose Compared With Standard-Dose Oxytocin Regimens to Augment Labor in Nulliparous Women. Obstetrics And Gynecology 2021, 137: 991-998. PMID: 33957657, DOI: 10.1097/aog.0000000000004399.Peer-Reviewed Original ResearchConceptsHigh-dose groupHigh-dose oxytocin regimenStandard dosingAugmentation of laborUmbilical artery acidemiaLabor durationPrimary outcomeSecondary outcomesNulliparous womenCesarean birthNeonatal intensive care unit admissionIntensive care unit admissionApgar score 3Care unit admissionStandard-dose groupPrespecified secondary outcomesPrimary cesarean birthWeeks of gestationAugment laborClinical chorioamnionitisMorbidity compositeNulliparous participantsUnit admissionObstetric morbidityPerinatal outcomesHealth Resource Utilization of Labor Induction Versus Expectant Management
Grobman W, Sandoval G, Reddy U, Tita A, Silver R, Mallett G, Hill K, Rice M, El-Sayed Y, Wapner R, Rouse D, Saade G, Thorp J, Chauhan S, Iams J, Chien E, Casey B, Gibbs R, Srinivas S, Swamy G, Simhan H, Macones G. Health Resource Utilization of Labor Induction Versus Expectant Management. Obstetric Anesthesia Digest 2021, 41: 34-34. DOI: 10.1097/01.aoa.0000732480.32100.cf.Peer-Reviewed Original ResearchExpectant managementElective inductionNulliparous womenLow-risk nulliparous womenHealth care resource utilizationHealth resource utilizationNeonatal respiratory morbidityElective labor inductionARRIVE trialDelivery admissionHypertensive disordersCesarean deliveryLabor inductionRespiratory morbidityWeeks postpartumTrialsManagement trialsWeeksWomenInductionCurrent studyResource utilizationAntepartumMorbidityPregnancy726 Fetal growth by ultrasound prior to the diagnosis of gestational diabetes mellitus in nulliparous women
Mahdasian-Miller A, Scifres C, Haas D, Grobman W, Silver R, Wing D, Saade G, Reddy U, Simhan H. 726 Fetal growth by ultrasound prior to the diagnosis of gestational diabetes mellitus in nulliparous women. American Journal Of Obstetrics And Gynecology 2021, 224: s455-s456. DOI: 10.1016/j.ajog.2020.12.749.Peer-Reviewed Original Research
2020
Incident diabetes complications among women with type 1 diabetes based on parity
Polsky S, Foster NC, DuBose SN, Agarwal S, Lyons S, Peters AL, Uwaifo GI, DiMeglio LA, Sherr JL, Levy CJ. Incident diabetes complications among women with type 1 diabetes based on parity. The Journal Of Maternal-Fetal & Neonatal Medicine 2020, 35: 4629-4634. PMID: 33280471, DOI: 10.1080/14767058.2020.1858278.Peer-Reviewed Original ResearchConceptsType 1 diabetesParous womenNulliparous womenDiabetes complicationsRisk factorsHigher Body Mass IndexAdverse lipid profileTriglyceride/HDLOverweight/obesityBody mass indexAdvanced nephropathyMass indexT1D ExchangeFirst pregnancyPregnant womenChildbirth QuestionnaireLipid profileCardiovascular diseaseComplicationsWomenHypertensionYear 5Further studiesSignificant differencesDiabetesTerm Labor Induction and Cesarean Delivery Risk among Obese Women with and without Comorbidities
Glazer K, Danilack V, Field A, Werner E, Savitz D. Term Labor Induction and Cesarean Delivery Risk among Obese Women with and without Comorbidities. American Journal Of Perinatology 2020, 39: 154-164. PMID: 32722823, DOI: 10.1055/s-0040-1714422.Peer-Reviewed Original ResearchConceptsCesarean delivery riskLow-risk nulliparous womenPrior vaginal deliveryCesarean riskCesarean deliveryLabor inductionElective inductionNulliparous womenVaginal deliveryWeeks' gestationMaternal ageTerm inductionEarly term inductionTerm labor inductionPrior cesarean deliveryAdjusted risk ratioBody mass indexElective labor inductionWeeks of gestationDelivery riskRisk reductionARRIVE trialExpectant managementHypertensive disordersObstetric populationAssociation Between Time of Day and the Decision for an Intrapartum Cesarean Delivery.
Son M, Lai Y, Bailit J, Reddy UM, Wapner RJ, Varner MW, Thorp JM, Caritis SN, Prasad M, Tita ATN, Saade G, Sorokin Y, Rouse DJ, Blackwell SC, Tolosa JE. Association Between Time of Day and the Decision for an Intrapartum Cesarean Delivery. Obstetrics And Gynecology 2020, 135: 535-541. PMID: 32028489, PMCID: PMC7595762, DOI: 10.1097/aog.0000000000003707.Peer-Reviewed Original ResearchConceptsIntrapartum cesarean deliveryCesarean deliveryMedian durationNulliparous womenMulticenter observational cohortOverall cesarean deliveryCesarean delivery rateLive gestationEligible womenObservational cohortSecondary outcomesPrimary outcomeVertex presentationMedian timeFetal statusKruskal-Wallis testHome birthTime of daySecondary analysisComplete dilationBivariate analysisContinuous outcomesDystociaWomenNonlinear associationAssociation of Oxytocin Rest During Labor Induction of Nulliparous Women With Mode of Delivery.
McAdow M, Xu X, Lipkind H, Reddy UM, Illuzzi JL. Association of Oxytocin Rest During Labor Induction of Nulliparous Women With Mode of Delivery. Obstetrics And Gynecology 2020, 135: 569-575. PMID: 32028487, DOI: 10.1097/aog.0000000000003709.Peer-Reviewed Original ResearchConceptsMode of deliveryInduction of laborNeonatal morbidityCesarean deliveryNulliparous womenLatent laborOxytocin infusionLatent phaseMultivariable logistic regression analysisContinuous oxytocin infusionRetrospective cohort analysisLarge academic medical centerBody mass indexLogistic regression analysisAcademic medical centerContinuous oxytocinSingleton gestationsLabor inductionGestational ageMass indexPotential confoundersMaternal ageOdds ratioCohort analysisMedical Center
2019
Labor Induction Versus Expectant Management in Low-Risk Nulliparous Women
Grobman W, Rice M, Reddy U, Tita A, Silver R, Mallett G, Hill K, Thom E, El-Sayed Y, Perez-Delboy A, Rouse D, Saade G, Boggess K, Chauhan S, Iams J, Chien E, Casey B, Gibbs R, Srinivas S, Swamy G, Simhan H, Macones G. Labor Induction Versus Expectant Management in Low-Risk Nulliparous Women. Obstetrical & Gynecological Survey 2019, 74: 7-9. DOI: 10.1097/01.ogx.0000550506.01685.a7.Peer-Reviewed Original Research
2018
Defining Failed Induction of Labor
Grobman W, Bailit J, Lai Y, Reddy U, Wapner R, Varner M, Thorp J, Leveno K, Caritis S, Prasad M, Tita A, Saade G, Sorokin Y, Rouse D, Blackwell S, Tolosa J. Defining Failed Induction of Labor. Obstetric Anesthesia Digest 2018, 38: 215. DOI: 10.1097/01.aoa.0000547313.79293.f8.Peer-Reviewed Original Research
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