2025
Outcomes of medical and surgical management in infectious intracranial aneurysms: a multicenter cohort analysis
Alawieh A, Dimisko L, Zohdy Y, Koo A, Saad H, Baba B, Newman S, Grossberg J, Matouk C, Cawley C, Pradilla G, Reisner A, Fox W, Perez-Vega C, Burkhardt J, Salem M, Jabbour P, Naamani K, Schmidt R, Gooch M, Starke R, Abdelsalam A, Lu V, Levitt M, Chalhoub R, Kobeissy F, Spiotta A, Barrow D, Howard B. Outcomes of medical and surgical management in infectious intracranial aneurysms: a multicenter cohort analysis. Journal Of NeuroInterventional Surgery 2025, jnis-2025-023421. PMID: 40409986, DOI: 10.1136/jnis-2025-023421.Peer-Reviewed Original ResearchInfectious intracranial aneurysmsModified Rankin ScaleOutcome predictorsManagement of infectious intracranial aneurysmsEndovascular interventionIntracranial aneurysmsMedical managementComplication of systemic infectionRetrospective registry-based cohort studyHigh-risk patientsRegistry-based cohort studyStandardized management guidelinesTertiary care centerLimitations of medical managementPredictors of failureMultivariate logistic regressionDays of initiationMulticenter cohort analysisInfective endocarditisTreatment failureSurgical managementMulticenter cohortAneurysm sizeCase seriesClinical decision-makingAdherence to SVS Abdominal Aortic Aneurysm Guidelines Among Patients Detected by AI-Based Algorithm
Wilson E, Yao K, Kostiuk V, Bader J, Loh S, Mojibian H, Fischer U, Ochoa Chaar C, Aboian E. Adherence to SVS Abdominal Aortic Aneurysm Guidelines Among Patients Detected by AI-Based Algorithm. Annals Of Vascular Surgery 2025, 120: 108-114. PMID: 40349830, DOI: 10.1016/j.avsg.2025.05.007.Peer-Reviewed Original ResearchAbdominal aortic aneurysmAdherent patientsSurgical interventionAbdominal aortic aneurysm patientsNon-adherent patientsTertiary care centerFollow-up adherenceFollow-up algorithmSVS guidelinesImaging surveillanceSurgical criteriaAneurysm sizeAortic aneurysmIdentified patientsPati entsSurveillance adherenceVascular providersImaging scansDeceased patientsPatientsPhysician evaluationCare centerPatient outcomesStatistical significanceNo significant age differencesThe Incidence and Significance of Delayed Bleeding Events After Lower Extremity Revascularization in Patients with Advanced Peripheral Arterial Disease
Hundito A, Wells N, Tuttle M, Alameddine D, Huttler J, Slade M, Strosberg D, Lee A, Guzman R, Ochoa Chaar C. The Incidence and Significance of Delayed Bleeding Events After Lower Extremity Revascularization in Patients with Advanced Peripheral Arterial Disease. Journal Of Vascular Surgery 2025 PMID: 40187383, DOI: 10.1016/j.jvs.2025.03.394.Peer-Reviewed Original ResearchLower extremity revascularizationPeripheral arterial diseaseBleeding eventsBleeding episodesAdvanced peripheral arterial diseaseArtery diseaseAntithrombotic therapyExtremity revascularizationRetrospective review of patientsIncidence of bleeding eventsAssociated with worse overall outcomesDelayed bleeding eventsDiscontinuation of ASAPrescription of antithrombotic therapyRecurrent bleeding episodesReview of patientsChronic renal insufficiencyEnd-stage renal diseaseOutcomes of patientsTertiary care centerHistory of smokingRecurrent bleeding eventsLong-term outcomesCoronary artery diseaseLower-extremity revascularizationVariations in Antithrombotic Prescriptions and Evaluation of Extended Clopidogrel Therapy After Lower Extremity Revascularization for Peripheral Artery Disease
Wells N, Alameddine D, Dhanda U, Tran L, Silva D, Slade M, Guzman R, Ochoa Chaar C. Variations in Antithrombotic Prescriptions and Evaluation of Extended Clopidogrel Therapy After Lower Extremity Revascularization for Peripheral Artery Disease. Journal Of Vascular Surgery 2025 PMID: 40122313, DOI: 10.1016/j.jvs.2025.03.183.Peer-Reviewed Original ResearchLower extremity revascularizationPeripheral arterial diseaseDuration of clopidogrel therapyClopidogrel therapyAntithrombotic prescriptionAntithrombotic combinationsAntithrombotic therapyExtremity revascularizationArtery diseasePatients treated with clopidogrelAssociated with improved survivalClinical characteristics of patientsMedical records of patientsLong-term follow-upChronic renal insufficiencyMACE-free survivalAssociated with bleedingElectronic medical records of patientsAdverse cardiac eventsKaplan-Meier curvesRecords of patientsTertiary care centerCongestive heart failureLong-term outcomesComparison of patientsThe Use of Intravascular Ultrasound During Deep Venous Interventions in a Tertiary Care Center
Ali S, Rodriguez P, Abualanain E, Li Y, Khalil M, Aboloyoun H, Lozada J, Aboian E, Attaran R, Chaar C. The Use of Intravascular Ultrasound During Deep Venous Interventions in a Tertiary Care Center. Vascular And Endovascular Surgery 2025, 59: 505-512. PMID: 40096827, DOI: 10.1177/15385744251326989.Peer-Reviewed Original ResearchConceptsDeep venous interventionsPrimary patency rateVenous interventionsLoss of patencyPatency ratesAssociated with loss of patencyAssociated with fewer complicationsIVUS useMethodsThis retrospective studyTertiary care centerLower extremity interventionsChronic kidney diseaseMultiplanar venographyAssociated with lossConsecutive patientsRates of COPDPrimary patencyVenous stentingTechnical successFewer complicationsSymptomatic improvementVenous stenosisAnticoagulant useRetrospective studyHypercoagulable stateComparison of prognostic accuracy of HCC staging systems in patients undergoing TACE
Kasolowsky V, Gross M, Madoff D, Duncan J, Taddei T, Strazzabosco M, Jaffe A, Chapiro J. Comparison of prognostic accuracy of HCC staging systems in patients undergoing TACE. Clinical Imaging 2025, 120: 110438. PMID: 40049074, PMCID: PMC11967406, DOI: 10.1016/j.clinimag.2025.110438.Peer-Reviewed Original ResearchConceptsOverall survival of patientsBCLC staging systemTransarterial chemoembolizationOverall survivalStaging systemHepatocellular carcinomaStaging systems of hepatocellular carcinomaHepatocellular carcinoma staging systemsRetrospective single center studyKaplan Meier survival analysisInternational Staging SystemSingle center studyLog-rank testTertiary care centerPredicting Overall SurvivalMeier survival analysisConsecutive patientsPrognostic stratificationStudy endpointPrognostic accuracyCenter studyPrognostic powerStratify outcomesMultivariate analysisPatientsAssociation between isolated abnormal 1-hour glucose challenge test and adverse pregnancy outcomes: a retrospective review from an urban tertiary care center in the United States
Hosier H, Lundsberg L, Culhane J, Partridge C, Son M. Association between isolated abnormal 1-hour glucose challenge test and adverse pregnancy outcomes: a retrospective review from an urban tertiary care center in the United States. BMC Pregnancy And Childbirth 2025, 25: 145. PMID: 39934722, PMCID: PMC11817534, DOI: 10.1186/s12884-025-07214-x.Peer-Reviewed Original ResearchConceptsAbnormal 1-hour glucose challenge testGlucose challenge testNeonatal intensive care unitAdverse pregnancy outcomesIncreased riskMorbidity outcomesWeeks gestationPregnancy outcomesNeonatal intensive care unit admissionTransient tachypnea of theHypertensive disorders of pregnancyAssociated with adverse outcomesChallenge testDisorders of pregnancyUrban tertiary care centerNormal screening resultsRespiratory distress syndromeTertiary care centerRetrospective cohort studyMultivariate logistic regression modelNormal screeningIntensive care unitScreening resultsMultiple secondary outcomesSingleton fetuses
2024
The Impact of Obesity on the Prevalence and Complications of Perianal Fistulas of Crohn’s Disease
Youn J, Hsia K, Khadilkar S, Zeina T, Rai P, Rastogi A, Hussani S, Spence S, Adavelly P, Yanes J, Kotlier J, Sweigart B, Levy A, Friedman S. The Impact of Obesity on the Prevalence and Complications of Perianal Fistulas of Crohn’s Disease. Digestive Diseases And Sciences 2024, 70: 323-332. PMID: 39548039, DOI: 10.1007/s10620-024-08729-7.Peer-Reviewed Original ResearchPerianal fistulasPerianal surgeryImpact of obesityComplex fistulasCrohn's perianal fistulasFecal diversionCrohn's diseaseInflammatory bowel diseaseMedian timeBMI categoriesBackgroundThe incidence of obesityHistory of perianal fistulaIncreasing BMI categoryTertiary care centerPerianal fistula surgeryIncidence of obesityRates of obesityCross-sectional studyFistula surgeryAnal surgeryNo significant differenceBackgroundThe incidenceCD patientsFistulaMaximum BMIOpen and endovascular treatment of the common femoral artery in a tertiary care center
Wells N, Hundito A, Tuttle M, Alameddine D, Aboian E, Arhuidese I, Fischer U, Perez Lozada J, Guzman R, Ochoa Chaar C. Open and endovascular treatment of the common femoral artery in a tertiary care center. Journal Of Vascular Surgery 2024, 81: 386-396.e2. PMID: 39442735, PMCID: PMC11748354, DOI: 10.1016/j.jvs.2024.10.027.Peer-Reviewed Original ResearchLower extremity revascularizationTreated with open surgeryPeripheral arterial diseaseCFA endarterectomyEndovascular therapyOpen surgeryEndovascular treatmentEndovascular lower extremity revascularizationTreated with endovascular therapyCompared to open surgeryAssociated with higher perioperative complicationsLower extremity revascularization proceduresPost-operative bleedingFemoral arteryImprove patient selectionKaplan-Meier analysisTertiary care centerTertiary-care centerLong-term outcomesEndovascular treatment of peripheral arterial diseaseLonger hospital lengthMALE-free survivalMultivariate logistic regressionTreatment of peripheral arterial diseaseCommon femoral arteryEvaluating RhD Assessment By Automated Methodology: A Potential ‘Blind Spot’ For RhD Variant Identification
Yurtsever N, Tormey C, Bizzario L, Lee E. Evaluating RhD Assessment By Automated Methodology: A Potential ‘Blind Spot’ For RhD Variant Identification. American Journal Of Clinical Pathology 2024, 162: s163-s163. DOI: 10.1093/ajcp/aqae129.360.Peer-Reviewed Original ResearchRh immune globulinWilcoxon matched pairs signed rank testSubsets of patientsTertiary care centerAntigen test resultsGel testYears of ageAnti-D AntibodiesStatistically significant differenceTube testD antigen expressionBlood donor centersRHD genotypingImmune globulinD statusTested patientsAntigen testRHD variantsRBC unitsPatientsD antigenPartial DCare centerHospital-based transfusion servicesAntigenic typesA Single Center Exploratory Survey of Patients and Nurses on post-Surgical Oral Opioid Delivery Through Patient-Controlled Analgesia
Mirza D, Zha L, See C, Paoletti I, Dai F, Hocevar M, Li J, Wiznia D. A Single Center Exploratory Survey of Patients and Nurses on post-Surgical Oral Opioid Delivery Through Patient-Controlled Analgesia. Journal Of Pain Research 2024, 17: 2483-2494. PMID: 39081328, PMCID: PMC11288353, DOI: 10.2147/jpr.s461379.Peer-Reviewed Original ResearchMedical delayMedication deliveryAdministering pain medicationSurvey of patientsLiquid medicationsAcademic tertiary care centerOpioid deliveryAdministration of opioidsAssess nursesNurse feedbackNurses' opinionsNurse availabilityOral liquid medicationsNursing burdenNursing timeDelivery of medicationsNursesPain managementPatients' opinionsModerate satisfactionPain medicationPhysician's prescriptionPatient dissatisfactionTertiary care centerCare center1199-P: Tackling Transition of Care of Young Adults with Type 1 Diabetes—Preliminary Findings
DIAS A, CONSIDINE E, WEYMAN K, CARR D, TICHY E, SHERR J. 1199-P: Tackling Transition of Care of Young Adults with Type 1 Diabetes—Preliminary Findings. Diabetes 2024, 73 DOI: 10.2337/db24-1199-p.Peer-Reviewed Original ResearchYoung adultsYale-New Haven Children's HospitalAdult providersKnowledge deficitsStructured visitsFeasibility studyTertiary care centerT1D durationCare centerReproductive healthRe-administeredChildren's HospitalAdultsProspective studyVisitsImpact of substancesMultidisciplinary approachDiabetesPre-transition periodTarget glycemiaProvidersHealthHospitalParticipantsSocial workSeizure Assessment and Forecasting With Efficient Rapid-EEG
Kalkach-Aparicio M, Fatima S, Selte A, Sheikh I, Cormier J, Gallagher K, Avagyan G, Cespedes J, Krishnamurthy P, Elazim A, Khan N, Hussein O, Maganti R, Larocque J, Holla S, Desai M, Westover B, Hirsch L, Struck A. Seizure Assessment and Forecasting With Efficient Rapid-EEG. Neurology 2024, 103: e209621. PMID: 38875512, DOI: 10.1212/wnl.0000000000209621.Peer-Reviewed Original ResearchConceptsMonitoring of at-risk patientsRecords of patientsTertiary care centerReceiver operating characteristic curveCritically ill patientsAt-risk patientsClass II evidenceDiagnostic accuracy studiesOperating characteristics curveMedian ageSecondary endpointsPrevent overtreatmentNo significant differenceEEG reviewRisk stratificationNoninferiority marginAntiseizure medicationsClinical correlatesPrimary outcomeII evidenceEEG technologistsSeizure assessmentIll patientsComparative effectiveness studiesLow riskUltrasound-guided Axillary Artery Catheter Placement and Associated Complications in Critically Ill Patients
Cardona S, Gross A, Yu A, Bassily-Marcus A, Oropello J, Manasia A. Ultrasound-guided Axillary Artery Catheter Placement and Associated Complications in Critically Ill Patients. Journal Of Intensive Care Medicine 2024, 39: 916-921. PMID: 38794858, DOI: 10.1177/08850666241257417.Peer-Reviewed Original ResearchConceptsArtery catheter placementCritically ill patientsCatheter placementBody mass indexCatheter malfunctionArtery catheterVascular complicationsIll patientsMedian body mass indexCenter of patientsCatheter related complicationsRate of complicationsTertiary care centerIntensive care unitFemoral artery accessMedian ageAssociated complicationsRelated complicationsRetrospective studySurgical interventionCompartment syndromeUnivariate analysisMultiple cathetersMass indexClinical variablesPerioperative complications of minor and major reinterventions for peripheral arterial disease
Huttler J, Satam K, Kim T, Zhuo H, Zhang Y, Aboian E, Guzman R, Chaar C. Perioperative complications of minor and major reinterventions for peripheral arterial disease. Vascular 2024, 33: 446-455. PMID: 38597200, DOI: 10.1177/17085381241246907.Peer-Reviewed Original ResearchCatheter-directed thrombolysisLower-extremity revascularizationPeripheral arterial diseaseSurgical reinterventionPerioperative morbidityPerioperative outcomesAssociated with greater perioperative morbiditySubgroup analysisArtery diseaseReturn to the ORRetrospective review of electronic medical recordsPost-operative bleedingReview of electronic medical recordsIncreased perioperative morbidityAcute renal failureVascular Surgery guidelinesTertiary care centerSurgery guidelinesOpen surgeryPerioperative mortalityPerioperative complicationsRetrospective reviewWound infectionRenal failureReinterventionAcute Effects of Growth Hormone on the Cellular Immunologic Landscape in Pediatric Patients
Gujral J, Kidd B, Becker C, Golden E, Lee H, Kim-Schulze S, Yau M, Dudley J, Rapaport R. Acute Effects of Growth Hormone on the Cellular Immunologic Landscape in Pediatric Patients. Cureus 2024, 16: e57383. PMID: 38566781, PMCID: PMC10984134, DOI: 10.7759/cureus.57383.Peer-Reviewed Original ResearchTime-of-flight mass cytometryComplete blood countGrowth hormoneImmune systemDendritic cellsPediatric patientsAcute effectsAcute effects of growth hormoneMonocyte countProspective study of pediatric patientsStudy of pediatric patientsMass cytometryEffects of growth hormoneGH stimulation testsComplete blood count analysisAbsolute lymphocyte countWhite blood cell countAbsolute neutrophil countAbsolute monocyte countAbsolute eosinophil countTertiary care centerBlood cell countTotal white blood cell countGH statusGH responseClinical outcomes among initial survivors of cryptogenic new‐onset refractory status epilepsy (NORSE)
Costello D, Matthews E, Aurangzeb S, Doran E, Stack J, Wesselingh R, Dugan P, Choi H, Depondt C, Devinsky O, Doherty C, Kwan P, Monif M, O'Brien T, Sen A, Gaspard N. Clinical outcomes among initial survivors of cryptogenic new‐onset refractory status epilepsy (NORSE). Epilepsia 2024, 65: 1581-1588. PMID: 38498313, DOI: 10.1111/epi.17950.Peer-Reviewed Original ResearchActive epilepsyClinical outcomesMental health outcomesMonths post-dischargeMonths of dischargeTreatment strategiesAcute phaseHealth outcomesLonger-term outcomesGlobal disabilityPost-dischargeMinority of patientsTertiary care centerTailored treatment strategiesNature of treatmentSevere clinical syndromeCare centerDeterminants of outcomePsychiatric comorbiditiesWell-characterized casesFunctional outcomesSurvivorsInvestigated patientsFollow-upSpecialist centersUse of The Risk Assessment and Prediction Tool to Predict Same-day Discharge After Primary Hip and Knee Arthroplasty
Dupont M, Held M, Shah R, Cooper H, Neuwirth A, Hickernell T. Use of The Risk Assessment and Prediction Tool to Predict Same-day Discharge After Primary Hip and Knee Arthroplasty. JAAOS Global Research And Reviews 2024, 8: e22.00269. PMID: 38456719, PMCID: PMC10923310, DOI: 10.5435/jaaosglobal-d-22-00269.Peer-Reviewed Original ResearchConceptsSame-day dischargeTotal knee arthroplastyTotal hip arthroplastyTertiary care centerPreoperative screening toolReceiver operating characteristic curveRAPT scoreScreening toolLogistic regression analysisAssociated with same-day dischargeKnee arthroplastyCutoff valuePreoperative notesPredictive valueCare centerPatientsCharacteristic curveSame-dayDischarge dispositionDischarge planningRegression analysisArthroplastyPositive associationScoresCutoffPersistent and newly developed gastrointestinal symptoms after surgery for intestinal malrotation in children: Dysmotility or disorders of gut and brain interaction?
Patel D, Banks D, Hira B, Ford M, Ambartsumyan L, Rodriguez L. Persistent and newly developed gastrointestinal symptoms after surgery for intestinal malrotation in children: Dysmotility or disorders of gut and brain interaction? Journal Of Pediatric Gastroenterology And Nutrition 2024, 78: 827-835. PMID: 38451033, DOI: 10.1002/jpn3.12178.Peer-Reviewed Original ResearchResolution of symptomsIntestinal malrotationGI symptomsFollow-upIncidental diagnosisPersistent gastrointestinal (GIPresence of postoperative symptomsPediatric tertiary care centerLong-term outcome of childrenMedian Follow-UpFactors associated with lackMulticenter retrospective studyPostoperative follow-upTertiary care centerAge of diagnosisTime to diagnosisLong-term outcomesRome IV criteriaGastrointestinal (GIOutcomes of childrenIdiopathic diagnosisOutcome variablesAssociated with disordersAssociation of demographicsClinical presentationTHE IMPACT OF OBESITY ON THE PREVALENCE AND SEVERITY OF PERIANAL COMPLICATIONS OF CROHN'S DISEASE
Youn J, Hsia K, Khadilkar S, Zeina T, Rai P, Rastogi A, Adavelly P, Hussani S, Yanes J, Kotlier J, Spence S, Levy A, Friedman S. THE IMPACT OF OBESITY ON THE PREVALENCE AND SEVERITY OF PERIANAL COMPLICATIONS OF CROHN'S DISEASE. Inflammatory Bowel Diseases 2024, 30: s28-s28. DOI: 10.1093/ibd/izae020.064.Peer-Reviewed Original ResearchPrevalence of perianal diseaseSeverity of perianal diseaseBody mass indexInflammatory bowel diseasePerianal surgeryPerianal diseasePerianal fistula surgeryImpact of obesityFecal diversionPerianal fistulasCrohn's diseaseFistula surgeryMedian timeFamily historyHistory of perianal fistulaBody mass index categoriesFamily history of inflammatory bowel diseaseHistory of inflammatory bowel diseaseMaximum body mass indexIncreasing BMI categoryAssociation of obesityNon-obese patientsPerianal fistulizing diseaseCochran-Armitage trend testTertiary care center
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