High- vs low-dose oxytocin protocols for labor induction: a systematic review and meta-analysis
Grasch J, Costantine M, Cahill A, Subramaniam A, Son M, Raghuraman N, Grobman W, Frey H. High- vs low-dose oxytocin protocols for labor induction: a systematic review and meta-analysis. American Journal Of Obstetrics & Gynecology MFM 2025, 7: 101691. PMID: 40334983, DOI: 10.1016/j.ajogmf.2025.101691.Peer-Reviewed Original ResearchConceptsLow-dose oxytocin protocolsOxytocin protocolInduction of laborLabor inductionCesarean deliveryLow-dose protocolVaginal deliveryNeonatal outcome of inductionFrequency of postpartum hemorrhageRisk of cesarean deliveryLikelihood of cesarean deliveryDuration of labor inductionFrequency of cesarean deliveryHigh-dose oxytocin protocolRelative riskCochrane risk of bias assessment toolSystematic reviewRisk of bias assessment toolOxytocin infusion protocolOperative vaginal deliveryHigh-dose oxytocinConfidence intervalsDuration of laborOutcome of inductionHigh risk of bias
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