2022
Surgery or Endovascular Therapy for Chronic Limb-Threatening Ischemia
Farber A, Menard M, Conte M, Kaufman J, Powell R, Choudhry N, Hamza T, Assmann S, Creager M, Cziraky M, Dake M, Jaff M, Reid D, Siami F, Sopko G, White C, van Over M, Strong M, Villarreal M, McKean M, Azene E, Azarbal A, Barleben A, Chew D, Clavijo L, Douville Y, Findeiss L, Garg N, Gasper W, Giles K, Goodney P, Hawkins B, Herman C, Kalish J, Koopmann M, Laskowski I, Mena-Hurtado C, Motaganahalli R, Rowe V, Schanzer A, Schneider P, Siracuse J, Venermo M, Rosenfield K. Surgery or Endovascular Therapy for Chronic Limb-Threatening Ischemia. New England Journal Of Medicine 2022, 387: 2305-2316. PMID: 36342173, DOI: 10.1056/nejmoa2207899.Peer-Reviewed Original ResearchConceptsChronic limb-threatening ischemiaMajor adverse limb eventsAdverse limb eventsPrimary outcome eventGreat saphenous veinEndovascular groupSurgical groupSurgical revascularizationEndovascular therapySaphenous veinLimb eventsAdequate greater saphenous veinInfrainguinal peripheral artery diseaseChronic limb threatening ischemiaAlternative bypass conduitLimb threatening ischemiaLimb-threatening ischemiaPeripheral artery diseaseSaphenous vein conduitsRisk of amputationAdverse eventsLimb outcomesArtery diseasePrimary outcomeBypass conduit
2021
Angiographic Patency of Coronary Artery Bypass Conduits: A Network Meta‐Analysis of Randomized Trials
Gaudino M, Hameed I, Robinson NB, Ruan Y, Rahouma M, Naik A, Weidenmann V, Demetres M, Tam D, Hare DL, Girardi LN, Biondi‐Zoccai G, Fremes S. Angiographic Patency of Coronary Artery Bypass Conduits: A Network Meta‐Analysis of Randomized Trials. Journal Of The American Heart Association 2021, 10: e019206. PMID: 33686866, PMCID: PMC8174193, DOI: 10.1161/jaha.120.019206.Peer-Reviewed Original ResearchConceptsCoronary artery bypass conduitsTouch saphenous veinAngiographic patency ratesRadial arterySaphenous veinPatency ratesGraft occlusionRandomized trialsBypass conduitRight internal thoracic arteryTouch saphenous vein graftsCoronary bypass surgerySaphenous vein graftsGraft occlusion rateInternal thoracic arteryBest conduitNetwork Meta-AnalysisSystematic literature searchGastroepiploic arteryBypass surgeryPrimary outcomeThoracic arteryAngiographic patencyVein graftsOcclusion rate
2020
Location of reflux in the saphenous vein does not affect outcomes of vein ablation
Aurshina A, Cardella J, Sumpio B, Zhuo H, Zhang Y, Dardik A, Ochoa Chaar CI. Location of reflux in the saphenous vein does not affect outcomes of vein ablation. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2020, 9: 932-937. PMID: 33249108, DOI: 10.1016/j.jvsv.2020.11.013.Peer-Reviewed Original ResearchConceptsVenous ablationSaphenous veinElectronic medical recordsMean patient ageRecurrence of painSingle-center reviewIncidence of complicationsClinical success rateNumeric rating scaleTechnical success ratePatients' electronic medical recordsTelephone surveySuccess rateIntensity of symptomsValvular refluxCEAP classSymptomatic patientsConsecutive patientsOutpatient officePatient agePatient characteristicsVein ablationDuplex ultrasonographySymptom improvementBilateral treatmentLong-Term Results of the RAPCO Trials
Buxton B, Hayward P, Raman J, Moten S, Rosalion A, Gordon I, Seevanayagam S, Matalanis G, Benedetto U, Gaudino M, Hare D, Gaer J, Negri J, Komeda M, Bellomo R, Doolan L, McNicol L, Brennan J, Chan R, Clark D, Dick R, Dortimer A, Ecclestone D, Farouque O, Fernando D, Horrigan M, Jackson A, Oliver L, Mehta N, Nadurata V, Nadarajah N, Proimos G, Rowe M, Sia B, Webb C, Anaveker N, Barlis P, Calafiore P, Chan B, Cotroneo J, Johns J, Jones E, Kertes P, O’Donnell D, Sylviris S, Tonkin A, Fabini R, Kearney L, Lim R, Molan M, Smith G, Wellman C, Eng J, Hameed I, Shaw M, Gerbo S. Long-Term Results of the RAPCO Trials. Circulation 2020, 142: 1330-1338. PMID: 33017209, DOI: 10.1161/circulationaha.119.045427.Peer-Reviewed Original ResearchConceptsRight internal thoracic arteryFree right internal thoracic arteryRadial arteryPatient survival estimatesSaphenous veinYears of ageInternal thoracic artery graftsSurvival estimatesFree RITA graftThoracic artery graftsCoprimary end pointsCoronary bypass surgeryInternal thoracic arteryLong-term mortalityLong-term patencyCoronary targetsRA armRITA graftArtery graftBypass surgeryGraft failureRA groupPrimary outcomeThoracic arterySV graftsAssociation of Radial Artery Graft vs Saphenous Vein Graft With Long-term Cardiovascular Outcomes Among Patients Undergoing Coronary Artery Bypass Grafting
Gaudino M, Benedetto U, Fremes S, Ballman K, Biondi-Zoccai G, Sedrakyan A, Nasso G, Raman J, Buxton B, Hayward PA, Moat N, Collins P, Webb C, Peric M, Petrovic I, Yoo KJ, Hameed I, Di Franco A, Moscarelli M, Speziale G, Puskas JD, Girardi LN, Hare DL, Taggart DP. Association of Radial Artery Graft vs Saphenous Vein Graft With Long-term Cardiovascular Outcomes Among Patients Undergoing Coronary Artery Bypass Grafting. JAMA 2020, 324: 179-187. PMID: 32662861, PMCID: PMC7361649, DOI: 10.1001/jama.2020.8228.Peer-Reviewed Original ResearchConceptsCoronary artery bypassSaphenous vein graftsComposite of deathRadial artery graftArtery bypassVein graftsRadial arteryMyocardial infarctionArtery graftCardiovascular outcomesClinical outcomesSaphenous veinLong-term cardiovascular outcomesPatient-level pooled analysisCoronary Artery Bypass GraftingArtery Bypass GraftingIndividual participant dataBypass GraftingAdult patientsComposite outcomeSecondary outcomesPrimary outcomeRandomized trialsPooled analysisObservational study
2019
The RADial artery International ALliance (RADIAL) extended follow-up study: rationale and study protocol
Gaudino M, Benedetto U, Fremes S, Ballman K, Biondi-Zoccai G, Sedrakyan A, Nasso G, Raman J, Buxton B, Hayward PA, Moat N, Collins P, Webb C, Peric M, Petrovic I, Yoo KJ, Hameed I, Di Franco A, Moscarelli M, Speziale G, Girardi LN, Hare DL, Taggart DP, Investigators R. The RADial artery International ALliance (RADIAL) extended follow-up study: rationale and study protocol. European Journal Of Cardio-Thoracic Surgery 2019, 56: 1025-1030. PMID: 31535147, DOI: 10.1093/ejcts/ezz247.Peer-Reviewed Original ResearchConceptsPatency ratesSaphenous veinGood mid-term patency ratesMid-term patency ratesCoronary artery bypass surgeryRadial artery graftArtery bypass surgeryEvent-free survivalSaphenous vein graftsLong-term outcomesImproved patency ratesRA armArtery graftPostoperative yearRepeat revascularizationBypass surgeryCardiac eventsVein graftsClinical correlatesStudy protocolObservational studyRole of RASGraftTrialsSurvival
2018
Generating vascular conduits: from tissue engineering to three-dimensional bioprinting
Maina RM, Barahona MJ, Finotti M, Lysyy T, Geibel P, D’Amico F, Mulligan D, Geibel JP. Generating vascular conduits: from tissue engineering to three-dimensional bioprinting. Innovative Surgical Sciences 2018, 3: 203-213. PMID: 31579784, PMCID: PMC6604577, DOI: 10.1515/iss-2018-0016.Peer-Reviewed Original ResearchArtery diseaseVascular conduitsVascular diseaseAutologous graftsNative vesselsSuitable vascular conduitInternal mammary arteryPeripheral vascular diseaseRat vascular smooth muscle cellsThird of patientsCoronary artery diseaseCarotid artery diseaseVascular smooth muscle cellsStandard of careLimb-saving procedureSmooth muscle cellsMultivessel diseaseDonor graftsMammary arteryPoor outcomeSaphenous veinLeading causeVascular interventionsGraftMuscle cells
2017
Mechanochemical Ablation of Superficial Veins
Aurshina A, Ochoa Chaar C. Mechanochemical Ablation of Superficial Veins. 2017, 133-143. DOI: 10.1007/978-3-319-65226-9_10.Peer-Reviewed Original ResearchMechanochemical ablationTraditional surgical ligationEquivalent clinical efficacyEndovenous thermal ablationNonthermal ablative techniquesSurgical ligationVenous insufficiencyClinical efficacySaphenous veinAblative techniquesInvasive treatmentSuperficial veinsTumescent anesthesiaLess discomfortThermal ablationAblationVeinComplications of CO2 insufflation during endoscopic vein harvesting
Suarez‐Pierre A, Terasaki Y, Magruder J, Kapoor A, Grant M, Lawton J. Complications of CO2 insufflation during endoscopic vein harvesting. Journal Of Cardiac Surgery 2017, 32: 783-789. PMID: 29169212, DOI: 10.1111/jocs.13249.Peer-Reviewed Original ResearchPredictive value of telomere length on outcome following acute myocardial infarction: evidence for contrasting effects of vascular vs. blood oxidative stress
Margaritis M, Sanna F, Lazaros G, Akoumianakis I, Patel S, Antonopoulos AS, Duke C, Herdman L, Psarros C, Oikonomou EK, Shirodaria C, Petrou M, Sayeed R, Krasopoulos G, Lee R, Tousoulis D, Channon KM, Antoniades C. Predictive value of telomere length on outcome following acute myocardial infarction: evidence for contrasting effects of vascular vs. blood oxidative stress. European Heart Journal 2017, 38: 3094-3104. PMID: 28444175, PMCID: PMC5837455, DOI: 10.1093/eurheartj/ehx177.Peer-Reviewed Original ResearchConceptsPeripheral blood mononuclear cellsAcute myocardial infarctionVascular smooth muscle cellsVascular oxidative stressSaphenous veinMyocardial infarctionOxidative stressPredictive valueRecent acute myocardial infarctionCoronary artery bypassBlood mononuclear cellsClinical predictive valueBlood oxidative stressSmooth muscle cellsFunctional genetic polymorphismsEffects of vascularTissue-specific biomarkersArtery bypassProspective cohortConsecutive patientsClinical outcomesVascular factorsPost-AMIMononuclear cellsArtery segmentsAspirin-triggered resolvin D1 attenuates PDGF-induced vascular smooth muscle cell migration via the cyclic adenosine monophosphate/protein kinase A (cAMP/PKA) pathway
Mottola G, Chatterjee A, Wu B, Chen M, Conte MS. Aspirin-triggered resolvin D1 attenuates PDGF-induced vascular smooth muscle cell migration via the cyclic adenosine monophosphate/protein kinase A (cAMP/PKA) pathway. PLOS ONE 2017, 12: e0174936. PMID: 28362840, PMCID: PMC5376330, DOI: 10.1371/journal.pone.0174936.Peer-Reviewed Original ResearchConceptsAT-RvD1Vascular smooth muscle cell migrationALX/FPR2Smooth muscle cell migrationVSMC migrationMuscle cell migrationRp-8-BrResolvin D1Specialized pro-resolving lipid mediatorsAspirin-triggered resolvin D1Pro-resolving lipid mediatorsCyclic adenosine monophosphate/protein kinase A (cAMP/PKA) pathwayCAMP levelsHuman saphenous veinPlatelet-derived growth factorTreatment of VSMCCell migrationPKA activityIntracellular cAMP levelsCAMP/PKA pathwaySaphenous veinRac1 activityRvD1 receptorIntimal hyperplasiaLipid mediators
2016
Operative Anatomy of the Medial Gastrocnemius Recession vs the Proximal Medial Gastrocnemius Recession
Kaplan N, Fowler X, Maqsoodi N, DiGiovanni B, Oh I. Operative Anatomy of the Medial Gastrocnemius Recession vs the Proximal Medial Gastrocnemius Recession. Foot & Ankle International 2016, 38: 424-429. PMID: 28367689, DOI: 10.1177/1071100716682993.Peer-Reviewed Original ResearchConceptsSmall saphenous veinGastrocnemius recessionGreat saphenous veinSaphenous veinSemimembranosus tendonTibial nerveOperative treatmentPopliteal arterySaphenous nerveGastrocnemius releaseGastrocnemius muscleAnatomic structuresMedial sural cutaneous nerveSafe alternativeProximal medial gastrocnemius releaseEffective operative treatmentOne-thirdCutaneous nerveGastrocnemius contractureCadaveric lower leg specimensGastrocnemius fasciaLower leg specimensMedial gastrocnemiusAnkle pathologyAnatomic basisSurgical Anatomy of a Novel Medial Gastrocnemius Recession versus the Proximal Medial Gastrocnemius Recession
Oh I, DiGiovanni B, Kaplan N, Fowler X. Surgical Anatomy of a Novel Medial Gastrocnemius Recession versus the Proximal Medial Gastrocnemius Recession. Foot & Ankle Orthopaedics 2016, 1: 2473011416s00097. DOI: 10.1177/2473011416s00097.Peer-Reviewed Original ResearchMedial sural cutaneous nerveGastrocnemius recessionSmall saphenous veinGreat saphenous veinSaphenous veinSurgical marginsSemimembranosus tendonCutaneous nerveSaphenous nerveTibial nervePopliteal arteryGastrocnemius muscleNeurovascular structuresGreater riskAnatomic structuresEffective surgical treatmentMajor neurovascular structuresAttractive surgical optionWarrants further investigationStrayer procedureGastrocnemius contractureSurgical treatmentProximal releaseClinical efficacySurgical options
2011
Remember the Saphenous
Riera A, Langhan M, Northrup V, Santucci K, Chen L. Remember the Saphenous. Pediatric Emergency Care 2011, 27: 1121-1125. PMID: 22134232, DOI: 10.1097/pec.0b013e31823ab926.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAnthropometryAttitude of Health PersonnelBody SizeCatheterization, PeripheralChild, PreschoolEmergency NursingEmergency Service, HospitalFemaleHospitals, PediatricHumansInfantInfusions, IntravenousMaleNursing Staff, HospitalPediatric NursingPoint-of-Care SystemsSaphenous VeinUltrasonography, InterventionalConceptsAntecubital veinSaphenous veinHand veinsPeripheral veinUrban pediatric emergency departmentPediatric emergency departmentNursing preferencePatient characteristicsEmergency departmentSonographic findingsBedside ultrasoundUltrasound guidanceNursing staffMean widthStaff nursesAge groupsSecondary objectiveTransverse diameterFirst choiceUltrasound measurementsVeinSuccess rateSignificant differencesChildrenFuture studiesFIVE-YEAR FOLLOW-UP OF POLYTETRAFLUOROETHYLENE-COVERED STENTS COMPARED WITH BARE METAL STENTS IN AORTOCORONARY SAPHENOUS VEIN GRAFTS: THE RANDOMIZED BARRICADE TRIAL
Genereux P, Goldberg S, O'Shaughnessy C, Midei M, Siegel R, Mintz G, Cristea E, Dangas G, Lansky A, Mehran R, Stone G. FIVE-YEAR FOLLOW-UP OF POLYTETRAFLUOROETHYLENE-COVERED STENTS COMPARED WITH BARE METAL STENTS IN AORTOCORONARY SAPHENOUS VEIN GRAFTS: THE RANDOMIZED BARRICADE TRIAL. Journal Of The American College Of Cardiology 2011, 57: e1621. DOI: 10.1016/s0735-1097(11)61621-5.Peer-Reviewed Original ResearchImaging of alcohol‐induced dopamine release in rats:Preliminary findings with [11C]raclopride PET
Sullivan JM, Risacher SL, Normandin MD, Yoder KK, Froehlich JC, Morris ED. Imaging of alcohol‐induced dopamine release in rats:Preliminary findings with [11C]raclopride PET. Synapse 2011, 65: 929-937. PMID: 21308803, PMCID: PMC3130821, DOI: 10.1002/syn.20921.Peer-Reviewed Original ResearchConceptsPositron emission tomographyBlood alcohol concentrationSmall animal positron emission tomographyRat striatumAnimal positron emission tomographyP ratsAlcohol-induced dopamine releaseSignificant alcohol-induced decreaseAlcohol-induced decreaseBlood alcohol levelsLateral saphenous veinAlcohol-preferring ratsAnimals 10 minSystemic alcoholDA releaseMicrodialysis studyStriatal dopamineAlcohol administrationSaphenous veinMale WistarDopamine releaseLarge cohortExtracellular dopamineBlood samplesReceptor availability5-Year Follow-Up of Polytetrafluoroethylene-Covered Stents Compared With Bare-Metal Stents in Aortocoronary Saphenous Vein Grafts The Randomized BARRICADE (Barrier Approach to Restenosis: Restrict Intima to Curtail Adverse Events) Trial
Stone GW, Goldberg S, O'Shaughnessy C, Midei M, Siegel RM, Cristea E, Dangas G, Lansky AJ, Mehran R. 5-Year Follow-Up of Polytetrafluoroethylene-Covered Stents Compared With Bare-Metal Stents in Aortocoronary Saphenous Vein Grafts The Randomized BARRICADE (Barrier Approach to Restenosis: Restrict Intima to Curtail Adverse Events) Trial. JACC Cardiovascular Interventions 2011, 4: 300-309. PMID: 21435608, DOI: 10.1016/j.jcin.2010.11.013.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryChi-Square DistributionCoated Materials, BiocompatibleCoronary AngiographyCoronary Artery BypassCoronary RestenosisFemaleGraft Occlusion, VascularHumansKaplan-Meier EstimateMaleMetalsMiddle AgedMyocardial InfarctionPlatelet Aggregation InhibitorsPolytetrafluoroethyleneProspective StudiesProsthesis DesignRisk AssessmentRisk FactorsSaphenous VeinStentsThrombosisTime FactorsTreatment OutcomeUnited StatesConceptsSaphenous vein graftsBare metal stentsPercutaneous coronary interventionDiseased saphenous vein graftsHigh-pressure implantationDual antiplatelet therapyTarget vessel failureAntiplatelet therapyMajor secondary end pointEnd pointPrimary end pointSecondary end pointsLong-term prognosisBinary restenosisBMS patientsCoronary interventionVein graftsVessel failureInferior outcomesSaphenous veinDiscrete lesionsPatientsPrior trialsJostentLesions
2010
Umbilical Vein Grafts for Lower Limb Revascularization
Dardik A, Dardik H. Umbilical Vein Grafts for Lower Limb Revascularization. 2010, 189-198. DOI: 10.1007/978-1-84882-718-9_19.ChaptersTechniques and results of portal vein/superior mesenteric vein reconstruction using femoral and saphenous vein during pancreaticoduodenectomy
Lee D, Mitchell E, Jones M, Landry G, Liem T, Sheppard B, Billingsley K, Moneta G. Techniques and results of portal vein/superior mesenteric vein reconstruction using femoral and saphenous vein during pancreaticoduodenectomy. Journal Of Vascular Surgery 2010, 51: 662-666. PMID: 20080375, DOI: 10.1016/j.jvs.2009.09.025.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaEdemaEndosonographyFemoral VeinGraft Occlusion, VascularHumansKaplan-Meier EstimateMesenteric VeinsMiddle AgedNeoplasm InvasivenessPancreatic NeoplasmsPancreaticoduodenectomyPortal VeinRegistriesReoperationSaphenous VeinTime FactorsTissue and Organ HarvestingTomography, X-Ray ComputedTreatment OutcomeUltrasonography, Doppler, DuplexVascular PatencyVascular Surgical ProceduresConceptsPV/SMV reconstructionLower extremity edemaLower extremity veinsPostoperative wound problemsLate mortalityExtremity edemaFemoral veinExtremity veinsSaphenous veinWound problemsPreoperative imagingPortal veinPV/SMV invasionSuperior mesenteric vein invasionPreoperative computed tomography (CT) imagingPV/SMVVein harvest siteLower extremity complicationsKaplan-Meier analysisGreat saphenous veinMinor operative proceduresEndoscopic ultrasound scanSuperior mesenteric vein reconstructionComputed tomography (CT) imagingPatent reconstruction
2009
Fate of varicose veins after great saphenous vein stripping alone.
Nishibe T, Kondo Y, Dardik A, Muto A, Nishibe M. Fate of varicose veins after great saphenous vein stripping alone. International Angiology 2009, 28: 311-4. PMID: 19648875.Peer-Reviewed Original Research
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