2025
Injury to Internal Thoracic Artery to Left Anterior Descending Artery Grafts in Cardiac Reoperations
Insler J, Ramsingh R, Bakhos J, Houghtaling P, Koprivanac M, Svensson L, Blackstone E, Bakaeen F. Injury to Internal Thoracic Artery to Left Anterior Descending Artery Grafts in Cardiac Reoperations. JAMA Surgery 2025, 160: 354-356. PMID: 39661360, PMCID: PMC11904727, DOI: 10.1001/jamasurg.2024.4952.Peer-Reviewed Original ResearchNovel Bone and Marrow Harvesting Approach Through Posterior Subtalar Screw Tunnel for Revision Talonavicular Joint Arthrodesis.
Au A, Blume P. Novel Bone and Marrow Harvesting Approach Through Posterior Subtalar Screw Tunnel for Revision Talonavicular Joint Arthrodesis. Journal Of The American Podiatric Medical Association 2025, 115 PMID: 40126983, DOI: 10.7547/22-175.Peer-Reviewed Original ResearchConceptsTalonavicular joint arthrodesisAutologous cancellous bone graftCancellous bone graftTalonavicular jointBone graftJoint arthrodesisDonor siteScrew tunnelsLong-term outcome measuresRigid internal fixationWalking bootMarrow harvestPain-freeBone marrowCase reportPainful nonunionFollow-upInternal fixationSite incisionOutcome measuresOsseous unionArthrodesis siteRevision arthrodesisGraftMarrow
2024
Advocating for a “shift-to-left” in transplant oncology: left grafts, RAPID and dual graft
Cillo U, Furlanetto A, Gringeri E, Bertacco A, Marchini A, Rosso E, Bassi D, D’Amico F, Line P. Advocating for a “shift-to-left” in transplant oncology: left grafts, RAPID and dual graft. Updates In Surgery 2024, 1-14. PMID: 39120859, DOI: 10.1007/s13304-024-01919-y.Peer-Reviewed Original ResearchLiving donor liver transplantationRisk of small-for-size syndromeSmall-for-size syndromeDual-graft living donor liver transplantationHigh-volume transplant centerDonor liver transplantationDonor-recipient matchingShortage of graftsLeft-lobeLiver transplantationRight-lobeOncological indicationsTransplant oncologyDonor hepatectomyDual graftsTransplant centersHigh riskLeft graftGraftTissue engineered vascular grafts are resistant to the formation of dystrophic calcification
Turner M, Blum K, Watanabe T, Schwarz E, Nabavinia M, Leland J, Villarreal D, Schwartzman W, Chou T, Baker P, Matsumura G, Krishnamurthy R, Yates A, Hor K, Humphrey J, Marsden A, Stacy M, Shinoka T, Breuer C. Tissue engineered vascular grafts are resistant to the formation of dystrophic calcification. Nature Communications 2024, 15: 2187. PMID: 38467617, PMCID: PMC10928115, DOI: 10.1038/s41467-024-46431-4.Peer-Reviewed Original ResearchConceptsTissue-engineered vascular graftsTissue Engineered Vascular GraftsVascular graftsCongenital heart surgeryComputational fluid dynamics simulationsFluid dynamics simulationsPolytetrafluoroethylene graftHeart surgeryDystrophic calcificationRetrospective clinical studyGraft complianceDegree of calcificationClinical studiesProsthetic biomaterialsBiomaterialsAnimal modelsPolytetrafluoroethyleneHemodynamic performanceNatural historyCalcificationGraftOvine modelVascular conduitsLong-term successSurgery
2023
Post-transplantation cyclophosphamide is associated with increased bacterial infections
Ustun C, Chen M, Kim S, Auletta J, Batista M, Battiwalla M, Cerny J, Gowda L, Hill J, Liu H, Munshi P, Nathan S, Seftel M, Wingard J, Chemaly R, Dandoy C, Perales M, Riches M, Papanicolaou G. Post-transplantation cyclophosphamide is associated with increased bacterial infections. Bone Marrow Transplantation 2023, 59: 76-84. PMID: 37903992, PMCID: PMC11164622, DOI: 10.1038/s41409-023-02131-z.Peer-Reviewed Original ResearchConceptsPost-transplant cyclophosphamideHematopoietic cell transplantationBacterial infectionsMost bacterial infectionsGVHD prophylaxisInfection cohortHost diseaseCalcineurin inhibitorsMyelodysplastic syndromeCell transplantationAcute leukemiaMore infectionsDay 180Greater incidencePatientsInfectionCohortProphylaxisCyclophosphamideTransplantationSyndromeGraftLeukemiaMortalityIncidenceSurgical Correction of Vaginal Agenesis via Modified Laparoscopic Vecchietti Procedure
Esencan E, St Martin B, Harmanli O, Vash-Margita A. Surgical Correction of Vaginal Agenesis via Modified Laparoscopic Vecchietti Procedure. Journal Of Pediatric And Adolescent Gynecology 2023, 36: 556-559. PMID: 37354985, DOI: 10.1016/j.jpag.2023.06.004.Peer-Reviewed Original ResearchConceptsLaparoscopic Vecchietti procedureVecchietti procedureVaginal dilationVaginal agenesisSurgical correctionRudimentary uterine hornExtensive counselingMayer-RokitanskyNormal ovariesSuture adjustmentPrimary amenorrheaSecondary sex characteristicsUterine hornVaginal canalAgenesisSex characteristicsType IDilationUnsuccessful attemptsAmenorrheaNeovaginaPatientsVaginoplastyMucosaGraftComplications after Prostate Cancer Treatment: Pathophysiology and Repair of Post-Radiation Urethral Stricture Disease
Sterling J, Rahman S, Varghese A, Angulo J, Nikolavsky D. Complications after Prostate Cancer Treatment: Pathophysiology and Repair of Post-Radiation Urethral Stricture Disease. Journal Of Clinical Medicine 2023, 12: 3950. PMID: 37373644, PMCID: PMC10299043, DOI: 10.3390/jcm12123950.Peer-Reviewed Original ResearchUrethral stricture diseaseStricture diseaseBuccal graftRadiation therapyReconstructive optionsRobotic reconstructionLong-term success rateProstate cancer treatmentLimited long-term successPrimary reconstructive optionPelvic cancerVascular insultUrethral strictureEndoscopic approachClinical challengeClinical practiceMultiple interventionsSuccessful outcomeCancer treatmentDiseaseGraftLong-term successSuccess rateUrethroplastyUrologistsEphB4 monomer inhibits chronic graft vasculopathy in an aortic transplant model
Langford J, Gonzalez L, Taniguchi R, Brahmandam A, Zhang W, Dardik A. EphB4 monomer inhibits chronic graft vasculopathy in an aortic transplant model. JVS Vascular Science 2023, 4: 100109. PMID: 37519335, PMCID: PMC10372308, DOI: 10.1016/j.jvssci.2023.100109.Peer-Reviewed Original ResearchAortic transplant modelAllograft vasculopathyT cellsTransplant modelEphrin-B2Immune cell accumulationChronic graftCardiac transplantChronic rejectionTransplanted graftAortic allograftsNeointima formationCell accumulationTissue damageMonocyte adhesionLess neointima formationVasculopathyAdherent monocytesEndothelial surfaceReceptor EphB4MacrophagesGraftMonocytesImportant targetCellsCellular activation pathways and interaction networks in vascularized composite allotransplantation
Knoedler L, Knoedler S, Panayi A, Lee C, Sadigh S, Huelsboemer L, Stoegner V, Schroeter A, Kern B, Mookerjee V, Lian C, Tullius S, Murphy G, Pomahac B, Kauke-Navarro M. Cellular activation pathways and interaction networks in vascularized composite allotransplantation. Frontiers In Immunology 2023, 14: 1179355. PMID: 37266446, PMCID: PMC10230044, DOI: 10.3389/fimmu.2023.1179355.Peer-Reviewed Original ResearchConceptsVascularized Composite AllotransplantationComposite allotransplantationRecipient-derived lymphocytesTreatment of patientsCellular activation pathwaysMultidrug immunosuppressionVCA graftsVCA patientsVCA rejectionGraft rejectionDevastating injuriesClinical managementNovel therapiesReconstructive surgeryLimb lossRejection responseFacial disfigurementAllotransplantationPatientsGraftActivation pathwayTissue cellsDifferent cell typesTissue typesCell typesHyperspectral imaging to accurately segment skin erythema and hyperpigmentation in cutaneous chronic graft‐versus‐host disease
Saknite I, Kwun S, Zhang K, Hood A, Chen F, Kangas L, Kortteisto P, Kukkonen A, Spigulis J, Tkaczyk E. Hyperspectral imaging to accurately segment skin erythema and hyperpigmentation in cutaneous chronic graft‐versus‐host disease. Journal Of Biophotonics 2023, 16: e202300009. PMID: 36942511, PMCID: PMC11737863, DOI: 10.1002/jbio.202300009.Peer-Reviewed Original ResearchGraft-versus-host disease is locally maintained in target tissues by resident progenitor-like T cells
Sacirbegovic F, Günther M, Greco A, Zhao D, Wang X, Zhou M, Rosenberger S, Oberbarnscheidt M, Held W, McNiff J, Jain D, Höfer T, Shlomchik W. Graft-versus-host disease is locally maintained in target tissues by resident progenitor-like T cells. Immunity 2023, 56: 369-385.e6. PMID: 36720219, PMCID: PMC10182785, DOI: 10.1016/j.immuni.2023.01.003.Peer-Reviewed Original ResearchConceptsHost diseaseAllogeneic hematopoietic stem cell transplantationHematopoietic stem cell transplantationChronic antigen stimulationStem cell transplantationAlloreactive effectorsAdoptive transferCell transplantationΑβ TAntigen stimulationCell exhaustionGVHDRecipient tissuesEffector poolMajor causeCell clonesTarget tissuesAffected tissuesDiseaseGraftTissueTCF-1CellsDiseased tissuesMorbidity
2022
The use of nondirected donor organs in living donor liver transplantation: Perspectives and guidance
Fox AN, Liapakis A, Batra R, Bittermann T, Emamaullee J, Emre S, Genyk Y, Han H, Jackson W, Pomfret E, Raza M, Rodriguez‐Davalos M, Gold S, Samstein B, Shenoy A, Taner T, Roberts JP, Group T. The use of nondirected donor organs in living donor liver transplantation: Perspectives and guidance. Hepatology 2022, 75: 1579-1589. PMID: 34859474, DOI: 10.1002/hep.32260.Peer-Reviewed Original ResearchClinical and Ethical Framework for Liver Retransplantation Using Living Donor Grafts: A Western Perspective
Batra RK, Mulligan DC. Clinical and Ethical Framework for Liver Retransplantation Using Living Donor Grafts: A Western Perspective. Liver Transplantation 2022, 28: 760-762. PMID: 34931433, DOI: 10.1002/lt.26395.Peer-Reviewed Original ResearchDegloving Traumatic Lesser Toe Injury Reconstruction with Full-Thickness Skin Graft from Partially Amputated Autologous Toe Donor Site: A Case Report.
Gazes M, Au A, Jariwala T, Vyce S. Degloving Traumatic Lesser Toe Injury Reconstruction with Full-Thickness Skin Graft from Partially Amputated Autologous Toe Donor Site: A Case Report. Journal Of The American Podiatric Medical Association 2022, 112 PMID: 36115038, DOI: 10.7547/20-014.Peer-Reviewed Original ResearchConceptsFull-thickness skin graftAutologous full-thickness skin graftComplex soft tissue injuriesSoft tissue injuriesCase reportSkin graftsWound coverageExtensive degloving injuryHigh-energy traumaHigh-energy mechanismsMotor vehicle accidentsDegloving injuryLawnmower injuriesDistal amputationTraumatic injuryVehicle accidentsInjuryOpen fracturesInjury reconstructionWound closureSoft tissueDonor siteGraftReportWanted: An endothelial cell targeting atlas for nanotherapeutic delivery in allograft organs
Liburd ST, Shi AA, Pober JS, Tietjen GT. Wanted: An endothelial cell targeting atlas for nanotherapeutic delivery in allograft organs. American Journal Of Transplantation 2022, 22: 1754-1759. PMID: 35373446, PMCID: PMC9651180, DOI: 10.1111/ajt.17050.Peer-Reviewed Original ResearchConceptsNormothermic machine perfusionEndothelial cellsGraft vasculaturePoor outcomePreservation injuryMachine perfusionProfound shortageOrgan assessmentTransplant therapeuticsDonor comorbiditiesAllograft organClinical useOrgansAttractive targetNanotherapeutic deliveryTherapeutic vehiclesCellsTherapeutic deliveryDeliveryComorbiditiesTransplantGraftInjuryPerfusionVasculatureArtificial intelligence recognition of cutaneous chronic graft‐versus‐host disease by a deep learning neural network
McNeil A, Parks K, Liu X, Saknite I, Chen F, Reasat T, Cronin A, Wheless L, Dawant B, Tkaczyk E. Artificial intelligence recognition of cutaneous chronic graft‐versus‐host disease by a deep learning neural network. British Journal Of Haematology 2022, 197: e69-e72. PMID: 35322873, PMCID: PMC9197858, DOI: 10.1111/bjh.18141.Peer-Reviewed Original ResearchTwo Cases Surviving Macro Fat Emboli Complications Following Gluteal Fat Grafting
Wolfe E, Weber L, Wo L, Samaha M, Mathew P, Garcia O, Singh D. Two Cases Surviving Macro Fat Emboli Complications Following Gluteal Fat Grafting. Aesthetic Surgery Journal 2022, 42: 902-906. PMID: 35311886, DOI: 10.1093/asj/sjac063.Peer-Reviewed Original ResearchConceptsGluteal fat graftingFat graftingFat transferLack of published outcomesLow level of evidenceFatal pulmonary embolismAutologous fat transferLevel of evidenceTertiary care settingCase of survivalComplication ratePulmonary embolismLethal complicationCardiopulmonary compromiseGluteal augmentationIntravenous passageEarly recognitionGluteal contouringInjected fatIncreased patient demandComplicationsEmboliPublished studiesLethal eventGraftCan transfusion-associated graft-versus-host disease (TA-GvHD) be prevented with leukoreduction alone?
Rodriguez JV, Tormey CA. Can transfusion-associated graft-versus-host disease (TA-GvHD) be prevented with leukoreduction alone? Transfusion And Apheresis Science 2022, 61: 103402. PMID: 35288056, DOI: 10.1016/j.transci.2022.103402.Peer-Reviewed Original ResearchConceptsTransfusion-associated graftTA-GVHDHost diseaseCellular blood productsHigh mortality rateWhite blood cellsBlood productsEffective treatmentMortality rateTransfusion communityHigh mortalityMedical literatureBlood cellsDiseaseDevastating diseaseGraftLeukocytesLeukoreductionQuantitative reductionHospitalMortalityLimited evidence for graft selection in pediatric ACL reconstruction: a narrative review
De Petrillo G, Pauyo T, Franklin C, Chafetz R, Nault M, Veilleux L. Limited evidence for graft selection in pediatric ACL reconstruction: a narrative review. Journal Of Experimental Orthopaedics 2022, 9: 9. PMID: 35028782, PMCID: PMC8758832, DOI: 10.1186/s40634-022-00448-0.Peer-Reviewed Original ResearchAnterior cruciate ligament injuryGraft selectionCruciate ligament injuryEfficient return to sportsLigament injuriesAnterior cruciate ligament reconstructionSkeletally Immature PatientsPediatric ACL reconstructionReturn to sportCruciate ligament reconstructionKnee flexor/extensor strengthImmature patientsBone maturationACL reconstructionLigament reconstructionPatient recoveryPatientsNarrative reviewGraftLigament strengthPersonalized approachAnatomical characteristicsInjuryChapter 4 Biology of buccal mucosa in urological reconstruction
Sterling J, Policastro C, Nikolavsky D. Chapter 4 Biology of buccal mucosa in urological reconstruction. 2022, 81-104. DOI: 10.1016/b978-0-323-91199-3.00005-0.Peer-Reviewed Original ResearchBuccal mucosaBM graftsMucosa graftBuccal mucosa graftOral mucosa graftMultitude of injuriesComplex urethral stricturesOral mucosal tissuesSize of graftReconstructive urological surgeryLong stricturesUrethral strictureOral mucosaStandardized treatmentUrological surgeryMucosal tissuesUrological reconstructionGraftMucosal substituteSource of tissueRemarkable regenerative capacityMucosaGold standardHistochemical studiesRegenerative capacity
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