2025
OR2-22 | Percutaneous Coronary Intervention of True Coronary Bifurcation Lesions: A Frequentist Network Meta-Analysis of Six Strategies
Krishna M, Ezenna C, Joseph M, Al Mouslmani M, Nouri A, Akman Z, Rossi R, Nanna M, Goldsweig A. OR2-22 | Percutaneous Coronary Intervention of True Coronary Bifurcation Lesions: A Frequentist Network Meta-Analysis of Six Strategies. Journal Of The Society For Cardiovascular Angiography & Interventions 2025, 4: 102692. DOI: 10.1016/j.jscai.2025.102692.Peer-Reviewed Original ResearchF-41 | Intravascular Imaging, Invasive Physiology or Angiography Alone to Guide Percutaneous Coronary Intervention: A Bayesian Network Meta-Analysis
Krishna M, Ezenna C, Joseph M, Al Mouslmani M, Nouri A, Akman Z, Rossi R, Goldsweig A, Nanna M. F-41 | Intravascular Imaging, Invasive Physiology or Angiography Alone to Guide Percutaneous Coronary Intervention: A Bayesian Network Meta-Analysis. Journal Of The Society For Cardiovascular Angiography & Interventions 2025, 4: 103426. DOI: 10.1016/j.jscai.2025.103426.Peer-Reviewed Original ResearchANTITHROMBOTIC THERAPY AND OUTCOMES AFTER TRANSCATHETER AORTIC VALVE REPLACEMENT: AN UPDATED SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS
Siami S, Maleki S, Kazemian S, ebrahimi E, Ebrahimzade M, Jodeiri F, Hajiqasemi M, Ebrahimi S, Mehdizadeh M, Aghaei M, Bastan M, Sabet M, Nazari R, Ebrahimi P, Rana J, Nanna M, Giri J, Kolte D, Alkhouli M, Hosseini K. ANTITHROMBOTIC THERAPY AND OUTCOMES AFTER TRANSCATHETER AORTIC VALVE REPLACEMENT: AN UPDATED SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS. Journal Of The American College Of Cardiology 2025, 85: 888. DOI: 10.1016/s0735-1097(25)01372-5.Peer-Reviewed Original ResearchPost-Transcatheter Aortic Valve Replacement Antithrombotic Treatment in Nonindicated Patients Updated Systematic Review and Network Meta-Analysis
Siami S, Kazemian S, Maleki S, Ebrahimi E, Jodeiri F, Ebrahimzade M, Hajiqasemi M, Ebrahimi S, Mehdizadeh M, Aghaei M, Bastan M, Sabet M, Nazari R, Ebrahimi P, Rana J, Nanna M, Giri J, Kolte D, Biering-Sørensen T, Alkhouli M, Hosseini K. Post-Transcatheter Aortic Valve Replacement Antithrombotic Treatment in Nonindicated Patients Updated Systematic Review and Network Meta-Analysis. JACC Advances 2025, 4: 101719. PMID: 40286375, PMCID: PMC12049831, DOI: 10.1016/j.jacadv.2025.101719.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementDual antiplatelet therapyOral anticoagulantsAntithrombotic regimensNetwork Meta-AnalysisAntiplatelet therapyCardiovascular mortalityMyocardial infarctionRisk of all-cause mortalityChronic oral anticoagulationAortic valve replacementMeta-analysisOptimal antithrombotic strategyIncreased risk of mortalityFrequentist network meta-analysisRisk of cardiovascular mortalityChronic obstructive pulmonary diseaseAll-Cause MortalityRisk of mortalityObstructive pulmonary diseaseBleeding riskValve replacementAntithrombotic treatmentNo significant differenceAntithrombotic strategiesComparison of Endovascular Interventions for the Treatment of Superficial Femoral Artery Disease: A Network Meta-analysis
Schwartz A, Shah Y, Huang H, Nathan A, Fanaroff A, Giri J, Parikh S, Lansky A, Shah T. Comparison of Endovascular Interventions for the Treatment of Superficial Femoral Artery Disease: A Network Meta-analysis. Journal Of The Society For Cardiovascular Angiography & Interventions 2025, 4: 102432. PMID: 40061407, PMCID: PMC11887560, DOI: 10.1016/j.jscai.2024.102432.Peer-Reviewed Original ResearchPercutaneous transluminal angioplastyCutting Balloon AngioplastyDrug-Coated BalloonBare metal stentsDrug-eluting stentsTreatment of SFA diseaseNetwork Meta-AnalysisSuperficial femoral arteryPrimary patencyTechnical successEndovascular techniquesEndovascular interventionSystematic literature search of PubMedLiterature search of PubMedEndovascular treatment modalitiesMeta-analysisSFA diseaseDe novo lesionsTarget lesion revascularizationSearch of PubMedCritical limb ischemiaSystematic literature searchTreatment modalitiesSuperficial femoral artery diseaseLesion revascularizationSex Differences in the Safety and Efficacy of Different Durations of DAPT After PCI
Park D, Mahajan S, Fishman E, Ambrosini A, Acero L, Hu J, Campbell G, Babapour G, Kelsey M, Douglas P, Gupta A, Frampton J, Nanna M. Sex Differences in the Safety and Efficacy of Different Durations of DAPT After PCI. JACC Advances 2025, 4: 101543. PMID: 39886301, PMCID: PMC11780104, DOI: 10.1016/j.jacadv.2024.101543.Peer-Reviewed Original ResearchMonths of DAPTDuration of dual antiplatelet therapyNet adverse clinical eventsDuration of DAPTRandomized Controlled TrialsPercutaneous coronary interventionShorter duration of dual antiplatelet therapyRisk of bleedingBleeding riskLow risk of bleedingSex-based differencesAssociated with lower riskAdverse clinical eventsDual antiplatelet therapyAdverse cardiovascular eventsNetwork Meta-AnalysisWeb of Science databasesAntiplatelet therapyClinical impactCardiovascular eventsClinical eventsSystematic reviewSignificant sex-based differencesControlled TrialsCoronary intervention
2024
Second‐Line Treatment for Patients With Primary Biliary Cholangitis: A Systematic Review With Network Meta‐Analysis
Giannini E, Pasta A, Calabrese F, Labanca S, Marenco S, Pieri G, Torres M, Strazzabosco M. Second‐Line Treatment for Patients With Primary Biliary Cholangitis: A Systematic Review With Network Meta‐Analysis. Liver International 2024, 45: e16222. PMID: 39720853, PMCID: PMC11669080, DOI: 10.1111/liv.16222.Peer-Reviewed Original ResearchConceptsPrimary biliary cholangitisSecond-line treatmentNetwork Meta-AnalysisObeticholic acid 5Obeticholic acidBiliary cholangitisRelative riskIncomplete response to ursodeoxycholic acidPlacebo-controlled trial of patientsUrsodeoxycholic acidResponse to ursodeoxycholic acidSecond-line therapyIncreased risk of SAEsPlacebo-controlled trialIncidence of pruritusMeta-analysisTrial of patientsPrevent disease progressionRisk of SAEsCompare relative risksComparative efficacyDisease progressionIncreased riskBiochemical responsesSecondary outcomesPharmacological Interventions for Attention-Deficit/Hyperactivity Disorder in Children and Adolescents with Tourette Disorder: A Systematic Review and Network Meta-Analysis
Farhat L, Behling E, Landeros-Weisenberger A, de Barros P, Polanczyk G, Cortese S, Bloch M. Pharmacological Interventions for Attention-Deficit/Hyperactivity Disorder in Children and Adolescents with Tourette Disorder: A Systematic Review and Network Meta-Analysis. Journal Of Child And Adolescent Psychopharmacology 2024, 34: 373-382. PMID: 39320340, PMCID: PMC11807863, DOI: 10.1089/cap.2024.0049.Peer-Reviewed Original ResearchADHD symptomsAttention-deficit/hyperactivity disorderTic severityTourette's disorderAttention-deficit/hyperactivityRandomized Controlled TrialsA2 agonistPharmacological interventionsADHD symptom severityIncreased tic severityPersistent tic disordersNetwork Meta-AnalysisStandardized mean differencePairs of medicationsEfficacy of pharmacological interventionsWorsen ticsRandom-effects network meta-analysisSymptom severityTic disordersADHDMeta-analysisNetwork meta-analysis frameworkCertainty of evidenceDisordersNetwork meta-analysesP-057 Comparative Efficacy of Cilta-Cel vs Approved Comparator Treatments for Patients With Relapsed/Refractory Multiple Myeloma With 1–3 Prior Lines of Therapy: A Network Meta-Analysis
Mina R, Khan A, McClune B, Bar N, Caers J, Larsen J, Mendes J, Lee S, Benachour N, Chen D, Zhao M, Lonardi C, Slaughter A, Lengil T, Burnett H, Cichewicz A, Neupane B, Filho O, Dytfeld D, Sidana S. P-057 Comparative Efficacy of Cilta-Cel vs Approved Comparator Treatments for Patients With Relapsed/Refractory Multiple Myeloma With 1–3 Prior Lines of Therapy: A Network Meta-Analysis. Clinical Lymphoma Myeloma & Leukemia 2024, 24: s74. DOI: 10.1016/s2152-2650(24)01960-8.Peer-Reviewed Original ResearchComparative Analysis of PCI Strategies in Aortic Stenosis Patients Undergoing TAVI: A Systematic Review and Network Meta‐Analysis
Fallahtafti P, Soleimani H, Ebrahimi P, Ghaseminejad‐Raeini A, Karimi E, Shirinezhad A, Sabri M, Mehrani M, Taheri H, Siegel R, Shah N, Nanna M, Hakim D, Hosseini K. Comparative Analysis of PCI Strategies in Aortic Stenosis Patients Undergoing TAVI: A Systematic Review and Network Meta‐Analysis. Clinical Cardiology 2024, 47: e24324. PMID: 39054901, PMCID: PMC11272956, DOI: 10.1002/clc.24324.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationCoronary artery diseasePercutaneous coronary interventionIn-Hospital MortalityNetwork Meta-AnalysisMyocardial infarctionAortic stenosisAssociated with worse 30-day outcomeMeta-analysisIncreased risk of 1-year mortalityAssociated with higher 1-year mortalityRisk of 1-year mortalitySevere aortic stenosisFrequentist network meta-analysisRates of myocardial infarctionPercutaneous coronary intervention timeTime of revascularizationAortic valve implantationSevere ASNo significant differencePacemaker implantationPost-TAVIValve implantationPatient characteristicsArtery diseasePercutaneous Coronary Revascularization Strategies After Myocardial Infarction A Systematic Review and Network Meta-Analysis
Reddy R, Howard J, Jamil Y, Madhavan M, Nanna M, Lansky A, Leon M, Ahmad Y. Percutaneous Coronary Revascularization Strategies After Myocardial Infarction A Systematic Review and Network Meta-Analysis. Journal Of The American College Of Cardiology 2024, 84: 276-294. PMID: 38986670, DOI: 10.1016/j.jacc.2024.04.051.Peer-Reviewed Original ResearchConceptsRelative riskCardiovascular mortalityMyocardial infarctionMultivessel coronary artery diseaseAll-Cause MortalityAdverse cardiac eventsST-segment elevation myocardial infarctionComplete revascularizationCoronary artery diseaseBayesian network meta-analysesMortality reductionA Systematic ReviewNetwork meta-analysesElevation myocardial infarctionSystematic reviewMeta-analysesCardiac eventsArtery diseasePrimary outcomeNetwork Meta-AnalysisRevascularization strategyMeta-analysisHead-to-head trialsCoronary revascularization strategyAcute kidney injuryPharmacological Interventions for Pain Management in Diabetic Peripheral Neuropathy: A Network Meta-analysis of Randomised Controlled Trials (P5-13.003)
Suresh V, Dey D, Jayan M, Shamim M, Gupta S, Ramana D, Dave T, Jena R, Muneer M, Dhakal B, Ghosh S, Verma A, Garg A, Muzammil M, Bardhan M, Malhotra H, Kumar N, Mallick H, Roy B. Pharmacological Interventions for Pain Management in Diabetic Peripheral Neuropathy: A Network Meta-analysis of Randomised Controlled Trials (P5-13.003). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206325.Peer-Reviewed Original ResearchSAFETY AND EFFICACY OF ENDOVASCULAR TREATMENT MODALITIES FOR BELOW-THE-KNEE PERIPHERAL ARTERIAL DISEASE: A SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS
Tirziu D, Saleh A, Huang H, Akhlaghi N, Breen T, Parikh S, Rosenfield K, Armstrong E, Geraghty P, Brodmann M, Adams G, Snyder D, Zilinyi R, Altin S, Parise H, Lansky A. SAFETY AND EFFICACY OF ENDOVASCULAR TREATMENT MODALITIES FOR BELOW-THE-KNEE PERIPHERAL ARTERIAL DISEASE: A SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS. Journal Of The American College Of Cardiology 2024, 83: 843. DOI: 10.1016/s0735-1097(24)02833-x.Peer-Reviewed Original ResearchShorter Dual Antiplatelet Therapy for Older Adults After Percutaneous Coronary Intervention
Park D, Hu J, Jamil Y, Kelsey M, Jones W, Frampton J, Kochar A, Aronow W, Damluji A, Nanna M. Shorter Dual Antiplatelet Therapy for Older Adults After Percutaneous Coronary Intervention. JAMA Network Open 2024, 7: e244000. PMID: 38546647, PMCID: PMC10979312, DOI: 10.1001/jamanetworkopen.2024.4000.Peer-Reviewed Original ResearchConceptsOlder adultsMonths of DAPTDuration of dual antiplatelet therapySystematic reviewRandomized clinical trialsPercutaneous coronary interventionMeta-analysisPreferred Reporting ItemsAssess data qualityRisk of bleedingDuration of DAPTDual antiplatelet therapyWeb of ScienceMain OutcomesReporting ItemsData extractionAbstracted dataSecondary outcomesRisk ratioAntiplatelet therapyPrimary outcomeCochrane LibraryCoronary interventionReference groupNetwork Meta-AnalysisUltrasound-Guided Nerve Hydrodissection for the Management of Carpal Tunnel Syndrome: A Systematic Review and Network Meta-Analysis
Lee K, Park J, Yoon S, Kim M, Kim Y, Shin J, Lee S. Ultrasound-Guided Nerve Hydrodissection for the Management of Carpal Tunnel Syndrome: A Systematic Review and Network Meta-Analysis. Yonsei Medical Journal 2024, 65: 111-120. PMID: 39894044, PMCID: PMC11790405, DOI: 10.3349/ymj.2024.0089.Peer-Reviewed Original ResearchConceptsBoston Carpal Tunnel QuestionnaireBoston Carpal Tunnel Questionnaire symptomsCarpal tunnel syndromePlatelet-rich plasmaNetwork Meta-AnalysisNerve hydrodissectionEffective optionMeta-analysisTunnel syndromeNon-surgical treatmentCarpal Tunnel QuestionnaireDose of medicationLong-term symptom improvementTreatment of carpal tunnel syndromeSystematic reviewInitial symptom reliefManagement of carpal tunnel syndromeCumulative ranking curveRandom-effects modelStandardized mean differenceUltrasound variablesInjected doseElectrodiagnostic assessmentSymptom reliefWeb of Science
2023
Comparative effectiveness and cost-effectiveness of cardioprotective glucose-lowering therapies for type 2 diabetes in Brazil: a Bayesian network model
Nogueira A, Barreto J, Moura F, Luchiari B, Abuhab A, Bonilha I, Nadruz W, Gaziano J, Gaziano T, de Carvalho L, Sposito A. Comparative effectiveness and cost-effectiveness of cardioprotective glucose-lowering therapies for type 2 diabetes in Brazil: a Bayesian network model. Health Economics Review 2023, 13: 50. PMID: 37878108, PMCID: PMC10599033, DOI: 10.1186/s13561-023-00466-3.Peer-Reviewed Original ResearchIncremental cost-effectiveness ratioGlucose-lowering therapyType 2 diabetesNetwork Meta-AnalysisSecondary preventionPrevalence of type 2 diabetesBrazilian public health systemRisk of cardiovascular outcomesPublic health systemCost-effectiveReduced relative riskNon-fatal cardiovascular eventsContext of primary preventionConclusionsIn BrazilClasses of glucose-lowering therapiesHealth systemManagement of T2DMGLP-1aCost-effectiveness modelStandard carePrimary preventionCost-effectiveness ratioRelative riskEvidence-basedInternational dollarsNeuropathy as an adverse effect of proteasomal inhibitors in multiple myeloma treatment: a network meta-analysis (P11-8.004)
Garg A, Das A, Dasgupta S, Kumar S, Roy B. Neuropathy as an adverse effect of proteasomal inhibitors in multiple myeloma treatment: a network meta-analysis (P11-8.004). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000202155.Peer-Reviewed Original ResearchComparative efficacy and optimal duration of first-line antibiotic regimens for acute otitis media in children and adolescents: a systematic review and network meta-analysis of 89 randomized clinical trials
Kim M, Kim J, Ryu S, Lee S, Yon D, Kim E, Koyanagi A, Dragioti E, Shin J, Smith L. Comparative efficacy and optimal duration of first-line antibiotic regimens for acute otitis media in children and adolescents: a systematic review and network meta-analysis of 89 randomized clinical trials. World Journal Of Pediatrics 2023, 20: 219-229. PMID: 37016201, DOI: 10.1007/s12519-023-00716-8.Peer-Reviewed Original ResearchConceptsAcute otitis mediaThird-generation cephalosporinsAmoxicillin-clavulanateNetwork Meta-AnalysisAntibiotic durationClinical responseOtitis mediaAntibiotic useClinical outcome of acute otitis mediaFirst-line antibiotic regimenOutcome of acute otitis mediaTreatment durationDays of antibiotic useSource of antimicrobial resistanceMeta-analysisShorter treatment durationRandomized clinical trialsRandomized Controlled TrialsAntibiotic regimensClinical outcomesAntibiotic treatmentClinical impactRegimensAntimicrobial resistanceClinical trialsEffectiveness of Psychotherapy on Prevention of Suicidal Re-Attempts in Psychiatric Emergencies: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials
Jeong H, Yim H, Lee S, Potenza M, Kim N. Effectiveness of Psychotherapy on Prevention of Suicidal Re-Attempts in Psychiatric Emergencies: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. Psychotherapy And Psychosomatics 2023, 92: 152-161. PMID: 37015209, DOI: 10.1159/000529753.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyPrimary outcomePsychological interventionsPsychiatric emergenciesSystematic reviewPublication biasRandomized Controlled TrialsNetwork Meta-AnalysisPrevious suicide attemptsEfficacy of interventionsFirst-line psychological interventionEffectiveness of psychotherapyPotential effect moderatorsControlled TrialsCommon comparatorOnly interventionIndirect comparisonModerate qualityComparative effectivenessMeta-analysisSuicide attemptsBehavioral therapyCharacteristics of studiesData extractionEffect moderators
2022
Pharmacologic prevention of recurrent vasovagal syncope: A systematic review and network meta-analysis of randomized controlled trials
Behnoush A, Yazdani K, Khalaji A, Tavolinejad H, Aminorroaya A, Jalali A, Tajdini M. Pharmacologic prevention of recurrent vasovagal syncope: A systematic review and network meta-analysis of randomized controlled trials. Heart Rhythm 2022, 20: 448-460. PMID: 36509319, DOI: 10.1016/j.hrthm.2022.12.010.Peer-Reviewed Original ResearchConceptsHead-up tilt testPositive head-up tilt testNetwork Meta-AnalysisRandomized Controlled TrialsVasovagal syncopeMeta-analysisPharmacological therapyPrimary outcomeRisk ratioRandom-effects network meta-analysisSystematic reviewPooled risk ratioConfidence intervalsHealth care systemLevel of evidenceCumulative ranking curve analysisPairwise meta-analysisTreatment optionsWeb of ScienceSyncopal eventsTilt testCare systemComparative efficacySecondary outcomesCochrane Library
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