David Baddeley, PhD
About
Research
Publications
2024
Resolution in super-resolution microscopy — definition, trade-offs and perspectives
Prakash K, Baddeley D, Eggeling C, Fiolka R, Heintzmann R, Manley S, Radenovic A, Smith C, Shroff H, Schermelleh L. Resolution in super-resolution microscopy — definition, trade-offs and perspectives. Nature Reviews Molecular Cell Biology 2024, 25: 677-682. PMID: 38951703, DOI: 10.1038/s41580-024-00755-7.Peer-Reviewed Original ResearchElectrophysiology and 3D‐imaging reveal properties of human intracardiac neurons and increased excitability with atrial fibrillation
Ashton J, Prince B, Sands G, Argent L, Anderson M, Smith J, Tedoldi A, Ahmad A, Baddeley D, Pereira A, Lever N, Ramanathan T, Smaill B, Montgomery J. Electrophysiology and 3D‐imaging reveal properties of human intracardiac neurons and increased excitability with atrial fibrillation. The Journal Of Physiology 2024 PMID: 38687681, DOI: 10.1113/jp286278.Peer-Reviewed Original ResearchInduced action potential firingAction potential firingGP neuronsGanglionated plexiAtrial fibrillationPhenotypic neuronsAF patientsAutonomic neuronsPotential firingWhole cell patch-clamp techniqueAutonomic influencesAction potential firing rateIncreased synaptic densityAction potential accommodationSynaptic densityPatch-clamp techniqueAction potential kineticsOpen heart surgeryEpicardial adipose tissueInitiation of AFAutonomic ganglionated plexiControl of cardiac functionAction potential rateAutonomic nervous systemNoradrenergic phenotypeA correlative quantitative phase contrast and fluorescence super-resolution microscope for imaging molecules in their cellular context
Bao Y, Marin Z, Zhang C, Neugebauer K, Baddeley D, Shribak M, Bewersdorf J. A correlative quantitative phase contrast and fluorescence super-resolution microscope for imaging molecules in their cellular context. Biophysical Journal 2024, 123: 290a. DOI: 10.1016/j.bpj.2023.11.1808.Peer-Reviewed Original Research