John Geibel, DSc, MD, AGAF, MS, FRS
Professor Emeritus of Surgery (Gastrointestinal)Cards
About
Research
Overview
We are focused on 3 main areas; gastric ion transport in health and disease, intestinal ion transport in health and disease, and 3DBioprinting. For gastric ion transport we are focusing on means to modulate acid secretion and reverse erosion. We use a combination of natural products and biochemical modifications to treat acid disease at the cellular level. For studies of intestinal ion transport, we are focusing on how the calcium sensing receptor(CaSR) can modulate fluid transport during toxin induced diarrhea. We are also looking at nanoparticle therapies for Ulcerative Colitis. In addition we are investigating means to prevent ischemic injury by activating ionic pathways using the AMPKinase. Finally we are trying to prevent IBD/IBS associated epithelial injury in the gut by CaSR activation using nutraceuticals . For the 3DBioprinting area we are developing replacement conduits that can be used for the aorta, the inferior vena cava, and also as small and large intestine repair tool. Along with this research we are now examining the potential for intestinal elongation using a 3D printed replacement.
Medical Research Interests
Academic Achievements & Community Involvement
News & Links
Media
- Isolated gastric gland loaded with the pH sensitive dye BCECF and a lysosomal tracker on a Zeiss Spinning Disk confocal. Image shows 3-D reconstruction of the gland in real time.
News
- April 17, 2020
A new dimension to intestinal surgery
- September 12, 2017
Research in Surgery: A Brief Historical Overview
- February 12, 2016
Keeping the “Goldilocks” organ cool
- February 12, 2016
New artery? We can print that
Get In Touch
Contacts
Gastrointestinal Surgery
PO Box 208062
New Haven, CT 06520-8062
United States
Yale University
BML 232, 310 Cedar Street
New Haven, CT 06510
United States
Administrative Support
Locations
Brady Memorial Laboratory
Lab
310 Cedar Street, Ste 269/2
New Haven, CT 06510
General Information
203.737.1475Appointments
203.737.1485