Marc Hammarlund, PhD
Principal InvestigatorProfessor of Genetics and of Neuroscience
Degeneration — the same five axons, distal to the injury: beading, then myelin ovoids, then granular debris and a macrophage clearing it.
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Mitochondrial defects are tightly linked to axon degeneration, yet the underlying cellular mechanisms remain poorly understood. In Caenorhabditis elegans, PVQ axons that lack mitochondria degenerate spontaneously with age.
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Professor of Genetics and of Neuroscience