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Ania Jastreboff, MD, PhD

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About

Titles

Associate Professor of Medicine (Endocrinology)

Director, Yale Obesity Research Center (Y-Weight); Co-Director, Yale Center for Weight Management; Medical Director, Yale Stress Center

Biography

Ania M. Jastreboff, MD, PhD is an Associate Professor in Medicine and Pediatrics at Yale School of Medicine. Dr. Jastreboff is a clinically active physician-scientist and international thought leader in the scientific development and clinical application of novel anti-obesity pharmacotherapeutics revolutionizing obesity treatment. As founding director of the Yale Obesity Research Center (Y-Weight), she is leading and shaping pivotal landmark studies of dual- and triple-receptor hormone agonists and NIH-funded studies investigating the physiology of obesity. She has served as lead investigator and author for trials investigating novel nutrient-stimulated hormone (NuSH)-based therapies for obesity including dual hormone receptor agonist, tirzepatide, a GIP/GLP-1 receptor agonist (Jastreboff, et al., NEJM, 2022 & 2024) and triple hormone receptor agonist retatrutide, a GIP/GLP-1/Glucagon receptor agonist (Jastreboff, et al., NEJM, 2023). Trained in both adult endocrinology and pediatric endocrinology, she serves on the Board of Governance for The Obesity Society, as a director on the American Board of Obesity Medicine, developing Obesity Clinical Practice Guidelines, and as co-director of the Yale Center for Weight Management, where she sees patients and teach trainees. She is a highly sought after speaker, teaching nationally and internationally. She is also a compassionate advocate for patients with obesity, from grass-roots patient groups to interviews with Ms. Oprah Winfrey.


Videos of Dr. Jastreboff speaking with Ms. Oprah Winfrey about obesity (YouTube podcast)


Videos of Dr. Jastreboff and colleagues from the NEJM about:

- What causes obesity: https://www.nejm.org/doi/full/...

- Supporting patients with obesity: https://www.nejm.org/doi/full/...

- Medications and surgery for obesity treatment: https://www.nejm.org/doi/full/...


Yale video with Dr. Jastreboff about anti-obesity medications and the biology of obesity.

Podcast (Yale Talk) with the president of Yale University, Dr. Peter Salovey, speaking with Dr. Jastreboff.


Clinically, Dr. Jastreboff specializes in sophisticated use of anti-obesity medication combinations to help patients reach their weight and health goals.

Appointments

Other Departments & Organizations

Education & Training

Student - Yale Advanced Emerging Leaders
Yale University (2023)
Yale Public Voices Fellowship
Yale University (2022)
Clinical Scholar
Yale University School of Medicine (2013)
YCCI Clinical Research Scholar
Yale School of Medicine (2013)
PhD
Yale University Graduate School of Arts and Sciences, Investigative medicine (2012)
Neuromanaging in Psychiatry
Yale School of Medicine (2011)
Postdoctoral Fellowship
Yale School of Medicine (2011)
Postdoctoral Fellowship
Yale School of Medicine (2011)
Food Policy and Science
Yale University (2010)
Learning to Mentor the next generation of scientists
Yale School of Medicine (2009)
Nutrition and Chronic Disease
Yale University (2009)
Chief Resident
University of Maryland (2006)
Residency
University of Maryland School of Medicine (2006)
Intern
University of Maryland (2003)
MD
University of Maryland at Baltimore (2002)
BA
Bucknell University, Art History/Major, Music/Minor. Magna cum laude (1998)

Research

Overview

obesity and cancer; anti-obesity pharmacotherapy; cancer prevention and risk reduction

Medical Research Interests

Obesity; Weight Loss

Public Health Interests

Obesity

Research at a Glance

Yale Co-Authors

Frequent collaborators of Ania Jastreboff's published research.

Publications

2024

Clinical Trials

Current Trials

Academic Achievements & Community Involvement

  • activity

    The Obesity Society

  • activity

    The Endocrine Society

  • activity

    ADA (American Diabetes Association)

  • activity

    Obesity - National Childhood Obesity Awareness Month Special Issue

  • activity

    Diabetes Care

Clinical Care

Overview

Ania M. Jastreboff, MD, PhD, is an adult and pediatric endocrinologist with expertise in obesity medicine and weight management. She cares for patients who have prediabetes, insulin resistance, metabolic syndrome, and type 1 and type 2 diabetes.

Dr. Jastrebroff, who is director of the Yale Obesity Research Center (Y-Weight), says she empathizes with patients who struggle to lose weight or maintain weight loss. “Carrying excess weight and having obesity is not a lifestyle choice. Obesity is a chronic disease and should be treated with the same vigor and integrity as other chronic diseases,” she says. “We are in the infancy of our understanding of the mechanisms that underlie obesity. Many novel treatments are under development, including new anti-obesity medications, endoscopic procedures, and the refining of behavioral and surgical interventions.”

An assistant professor of medicine (endocrinology) and of pediatrics (endocrinology) at Yale School of Medicine, Dr. Jastrebroff says one of her goals is to conduct clinic research that will lead to better treatments for obesity and also have a clear public health impact in mitigating the obesity “pandemic.”

Clinical Specialties

Obesity Medicine; Pediatric Endocrinology & Diabetes; Diabetes Medicine & Management; Endocrinology

Fact Sheets

Board Certifications

  • Obesity Medicine

    Certification Organization
    AB of Obesity Medicine
    Original Certification Date
    2016
  • Endocrinology Diabetes & Metabolism

    Certification Organization
    AB of Internal Medicine
    Original Certification Date
    2012

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