Singh S, Tahmasian N, Liu JJ, Wang W, Haas L, Zhu Y, Griswold MM, Brodsky NN, Liu S, Kalish BT, Yimlamai D. Inflammatory monocytes constrain YAP-induced cell proliferation. Sci Adv 2026, 12: eaee8580. PMID: 42341114, DOI: 10.1126/sciadv.aee8580.
Peer-Reviewed Original Research
This study investigates how YAP and TAZ, key regulators of cell growth, drive opposing immune responses with TAZ promoting tumor growth and YAP being constrained by inflammatory monocytes.