Ying Wu, PhD
Associate Research ScientistAbout
Research
Publications
2026
Anti-CD3 mAb treatment reshapes infiltrating T and β cells in the islets in autoimmune diabetes
Wu Y, Spurrell M, Lledó-Delgado A, Deng S, Wang D, Liu Y, Barkestani M, Perdigoto A, Herold K. Anti-CD3 mAb treatment reshapes infiltrating T and β cells in the islets in autoimmune diabetes. JCI Insight 2026, 11: e192755. PMID: 41574610, PMCID: PMC12892913, DOI: 10.1172/jci.insight.192755.Peer-Reviewed Original Research
2022
RAGE antagonism with azeliragon improves xenograft rejection by T cells in humanized mice.
Joshi AA, Wu Y, Deng S, Preston-Hurlburt P, Forbes JM, Herold KC. RAGE antagonism with azeliragon improves xenograft rejection by T cells in humanized mice. Clinical Immunology 2022, 245: 109165. PMID: 36257528, DOI: 10.1016/j.clim.2022.109165.Peer-Reviewed Original Research
2021
Development of a fully canine anti-canine CTLA4 monoclonal antibody for comparative translational research in dogs with spontaneous tumors
Mason N, Chester N, Xiong A, Rotolo A, Wu Y, Yoshimoto S, Glassman P, Gulendran G, Siegel D. Development of a fully canine anti-canine CTLA4 monoclonal antibody for comparative translational research in dogs with spontaneous tumors. MAbs 2021, 13: 2004638. PMID: 34856888, PMCID: PMC8726733, DOI: 10.1080/19420862.2021.2004638.Peer-Reviewed Original Research
2020
Immunoregulatory Cells in Myasthenia Gravis
Wu Y, Luo J, Garden O. Immunoregulatory Cells in Myasthenia Gravis. Frontiers In Neurology 2020, 11: 593431. PMID: 33384654, PMCID: PMC7769807, DOI: 10.3389/fneur.2020.593431.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMyeloid-derived suppressor cell and regulatory T cell frequencies in canine myasthenia gravis: A pilot study
Wu Y, Chang Y, Lawson B, Galban E, Mittelman N, Benedicenti L, Petesch S, Carroll A, Punt J, Luo J, Garden O. Myeloid-derived suppressor cell and regulatory T cell frequencies in canine myasthenia gravis: A pilot study. The Veterinary Journal 2020, 267: 105581. PMID: 33375962, PMCID: PMC7780263, DOI: 10.1016/j.tvjl.2020.105581.Peer-Reviewed Original ResearchGene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation
Wu Y, Chang Y, Polton G, Stell A, Szladovits B, Macfarlane M, Peters L, Priestnall S, Bacon N, Kow K, Stewart S, Sharma E, Goulart M, Gribben J, Xia D, Garden O. Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation. Frontiers In Oncology 2020, 10: 307. PMID: 32211332, PMCID: PMC7069556, DOI: 10.3389/fonc.2020.00307.Peer-Reviewed Original Research
2019
Phenotypic characterisation of regulatory T cells in dogs reveals signature transcripts conserved in humans and mice
Wu Y, Chang Y, Stell A, Priestnall S, Sharma E, Goulart M, Gribben J, Xia D, Garden O. Phenotypic characterisation of regulatory T cells in dogs reveals signature transcripts conserved in humans and mice. Scientific Reports 2019, 9: 13478. PMID: 31530890, PMCID: PMC6748983, DOI: 10.1038/s41598-019-50065-8.Peer-Reviewed Original ResearchPhenotypic and transcriptomic characterization of canine myeloid-derived suppressor cells
Goulart M, Hlavaty S, Chang Y, Polton G, Stell A, Perry J, Wu Y, Sharma E, Broxholme J, Lee A, Szladovits B, Turmaine M, Gribben J, Xia D, Garden O. Phenotypic and transcriptomic characterization of canine myeloid-derived suppressor cells. Scientific Reports 2019, 9: 3574. PMID: 30837603, PMCID: PMC6400936, DOI: 10.1038/s41598-019-40285-3.Peer-Reviewed Original Research
2018
Diagnosis of anaplastic large-cell lymphoma in a dog using CD30 immunohistochemistry
Pittaway R, Wu Y, Szladovits B, Suárez-Bonnet A, Scurrell E, Garden O, Polton G, Priestnall S. Diagnosis of anaplastic large-cell lymphoma in a dog using CD30 immunohistochemistry. Journal Of Veterinary Diagnostic Investigation 2018, 30: 455-458. PMID: 29455626, PMCID: PMC6505805, DOI: 10.1177/1040638718760965.Peer-Reviewed Original Research
2017
Phenotypic heterogeneity of peripheral monocytes in healthy dogs
Gibbons N, Goulart M, Chang Y, Efstathiou K, Purcell R, Wu Y, Peters L, Turmaine M, Szladovits B, Garden O. Phenotypic heterogeneity of peripheral monocytes in healthy dogs. Veterinary Immunology And Immunopathology 2017, 190: 26-30. PMID: 28778319, DOI: 10.1016/j.vetimm.2017.06.007.Peer-Reviewed Original Research