William K. Oh, MD
Professor of Internal Medicine (Medical Oncology & Hematology)Cards
About
Research
Publications
2025
Practical Guide to Clinical Trial Accessibility: Making Trial Participation a Standard of Care.
Ebrahimi H, Allen J, Biru Y, Garg R, Hodgdon C, Oh WK, Steensma D, Pal SK, Mulvey T. Practical Guide to Clinical Trial Accessibility: Making Trial Participation a Standard of Care. Am Soc Clin Oncol Educ Book 2025, 45: e100052. PMID: 40388680, DOI: 10.1200/EDBK-25-100052.Peer-Reviewed Original ResearchProstate Cancer Foundation White Paper on Combination Therapy for Metastatic Hormone-Sensitive Prostate Cancer.
Carlsson S, Barata P, Bryce A, George D, Gillessen S, Loeb S, Montgomery B, Morris D, Riaz I, Palapattu G, Schoen M, Washington Iii S, Cornell B, Levine R, Aggarwal P, McGowan T, Cotter M, Thompson B, Devgan G, Russell D, Kuperman G, Lenero E, Iwata K, Miyahira A, Soule H, Carithers G, Oh W, Agarwal N. Prostate Cancer Foundation White Paper on Combination Therapy for Metastatic Hormone-Sensitive Prostate Cancer. JCO Oncology Practice 2025, op2500050. PMID: 40315399, DOI: 10.1200/op-25-00050.Peer-Reviewed Original ResearchMetastatic hormone-sensitive prostate cancerProstate Cancer FoundationHormone-sensitive prostate cancerCombination therapyProstate cancerPatients treated with combination therapyAndrogen receptor pathway inhibitorsBenefit of combination therapyQuality of lifeSignificant survival improvementUrban-dwelling patientsPreserving quality of lifeEnhanced survival outcomesGuideline-concordant careMeta-analysesRandomized controlled trialsDeprivation therapyEvidence-based therapiesSurvival outcomesTreatment utilization patternsSurvival improvementClinical trialsGlobal RegistryPathway inhibitorCombined treatmentDecoding Recurrence in Early-Stage and Locoregionally Advanced Non–Small Cell Lung Cancer: Insights From Electronic Health Records and Natural Language Processing
Lee K, Liu Z, Huang Q, Corrigan D, Kalsekar I, Jun T, Stolovitzky G, Oh W, Rajaram R, Wang X. Decoding Recurrence in Early-Stage and Locoregionally Advanced Non–Small Cell Lung Cancer: Insights From Electronic Health Records and Natural Language Processing. JCO Clinical Cancer Informatics 2025, 9: e2400227. PMID: 40249880, PMCID: PMC12011440, DOI: 10.1200/cci-24-00227.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerDistant metastasis-free survivalRecurrence-free survivalLocoregionally advanced non-small cell lung cancerAdvanced non-small cell lung cancerCell lung cancerStage I-IIIA non-small cell lung cancerNatural language processingLung cancerRecurrence-free survival ratesNon-small cell lung cancer recurrenceRisk factorsEarly-stageCox proportional hazards analysisStage IB patientsMetastasis-free survivalKaplan-Meier analysisNatural language processing systemsLikelihood of recurrenceAnalyze risk factorsProportional hazards analysisLocal/regional recurrenceRFS ratesCurative resectionStage IAIntravesical BCG therapy-induced granulomatous prostatitis in a patient with non-muscle invasive bladder cancer and prostate adenocarcinoma.
Yu R, Qin QJ, Haines GK, Oh WK, Lewis S. Intravesical BCG therapy-induced granulomatous prostatitis in a patient with non-muscle invasive bladder cancer and prostate adenocarcinoma. Urol Case Rep 2025, 60: 103020. PMID: 40230614, DOI: 10.1016/j.eucr.2025.103020.Peer-Reviewed Original ResearchFactors Affecting the Relationship Between Total and Unbound Bilirubin in Preterm and Term Infants
Hegyi T, Chefitz D, Weller A, Huber A, Carayannopoulos M, Oh W, Kleinfeld A. Factors Affecting the Relationship Between Total and Unbound Bilirubin in Preterm and Term Infants. Acta Paediatrica 2025 PMID: 40119546, DOI: 10.1111/apa.70067.Peer-Reviewed Original ResearchCharacterization of Exceptional Responses in Patients With Metastatic Castration-Resistant Prostate Cancer Treated With Cabozantinib and Immune Checkpoint Inhibitors
Ganta T, Anker J, Miller E, Joshi H, Tsao C, Oh W. Characterization of Exceptional Responses in Patients With Metastatic Castration-Resistant Prostate Cancer Treated With Cabozantinib and Immune Checkpoint Inhibitors. Clinical Genitourinary Cancer 2025, 23: 102336. PMID: 40222171, DOI: 10.1016/j.clgc.2025.102336.Peer-Reviewed Original ResearchMetastatic castration-resistant prostate cancerCastration-resistant prostate cancerImmune checkpoint inhibitorsProstate cancerCheckpoint inhibitorsHigh tumor mutational burdenLack of survival benefitProgression-free survivalTumor mutational burdenPopulation of patientsCastration-resistantRetrospective seriesMutational burdenSurvival benefitTreatment selectionCabozantinibPatientsCancerRegulatory approvalExceptional responseRegimenLong-term responseSubpopulationsInhibitorsTherapy
2024
How Can Guidelines Give Clearer Guidance on Prostate Cancer Screening?
Carlsson S, Oh W. How Can Guidelines Give Clearer Guidance on Prostate Cancer Screening? JAMA Oncology 2024, 10: 1497-1498. PMID: 39325462, DOI: 10.1001/jamaoncol.2024.3909.Peer-Reviewed Original ResearchWhat’s in a Name? Why Words Matter in Advanced Prostate Cancer
Oh W, Agarwal N, Bryce A, Barata P, Bugler C, Carlsson S, Cornell B, Dahut W, George D, Loeb S, Montgomery B, Morris D, Mucci L, Omlin A, Palapattu G, Riaz I, Ryan C, Schoen M, Washington S, Gillessen S. What’s in a Name? Why Words Matter in Advanced Prostate Cancer. European Urology 2024, 87: 101-103. PMID: 39472202, DOI: 10.1016/j.eururo.2024.10.017.Peer-Reviewed Original ResearchCriteriaMapper: establishing the automatic identification of clinical trial cohorts from electronic health records by matching normalized eligibility criteria and patient clinical characteristics
Lee K, Mai Y, Liu Z, Raja K, Jun T, Ma M, Wang T, Ai L, Calay E, Oh W, Schadt E, Wang X. CriteriaMapper: establishing the automatic identification of clinical trial cohorts from electronic health records by matching normalized eligibility criteria and patient clinical characteristics. Scientific Reports 2024, 14: 25387. PMID: 39455879, PMCID: PMC11511882, DOI: 10.1038/s41598-024-77447-x.Peer-Reviewed Original ResearchConceptsElectronic health recordsCell lung cancerEligibility criteriaClinical characteristicsLung cancerHealth recordsNon-small cell lung cancerSmall cell lung cancerPatient clinical characteristicsClinical trial cohortPatients' electronic health recordsIdentification of patientsClinical trial criteriaIdentification of eligible patientsSickle cell anemiaNon-alcoholic steatohepatitisStandardized terminologyProstate cancerMultiple myelomaTrial eligibility criteriaPatient selectionTrial cohortBreast cancerEligible patientsTrial criteriaManagement of Patients with Advanced Prostate Cancer. Report from the 2024 Advanced Prostate Cancer Consensus Conference (APCCC)
Gillessen S, Turco F, Davis I, Efstathiou J, Fizazi K, James N, Shore N, Small E, Smith M, Sweeney C, Tombal B, Zilli T, Agarwal N, Antonarakis E, Aparicio A, Armstrong A, Bastos D, Attard G, Axcrona K, Ayadi M, Beltran H, Bjartell A, Blanchard P, Bourlon M, Briganti A, Bulbul M, Buttigliero C, Caffo O, Castellano D, Castro E, Cheng H, Chi K, Clarke C, Clarke N, de Bono J, De Santis M, Duran I, Efstathiou E, Ekeke O, El Nahas T, Emmett L, Fanti S, Fatiregun O, Feng F, Fong P, Fonteyne V, Fossati N, George D, Gleave M, Gravis G, Halabi S, Heinrich D, Herrmann K, Hofman M, Hope T, Horvath L, Hussain M, Jereczek-Fossa B, Jones R, Joshua A, Kanesvaran R, Keizman D, Khauli R, Kramer G, Loeb S, Mahal B, Maluf F, Mateo J, Matheson D, Matikainen M, McDermott R, McKay R, Mehra N, Merseburger A, Morgans A, Morris M, Mrabti H, Mukherji D, Murphy D, Murthy V, Mutambirwa S, Nguyen P, Oh W, Ost P, O'Sullivan J, Padhani A, Parker C, Poon D, Pritchard C, Rabah D, Rathkopf D, Reiter R, Renard-Penna R, Ryan C, Saad F, Sade J, Sandhu S, Sartor O, Schaeffer E, Scher H, Sharifi N, Skoneczna I, Soule H, Spratt D, Srinivas S, Sternberg C, Suzuki H, Taplin M, Thellenberg-Karlsson C, Tilki D, Türkeri L, Uemura H, Ürün Y, Vale C, Vapiwala N, Walz J, Yamoah K, Ye D, Yu E, Zapatero A, Omlin A. Management of Patients with Advanced Prostate Cancer. Report from the 2024 Advanced Prostate Cancer Consensus Conference (APCCC). European Urology 2024, 87: 157-216. PMID: 39394013, DOI: 10.1016/j.eururo.2024.09.017.Peer-Reviewed Original ResearchConceptsAdvanced Prostate Cancer Consensus ConferenceProstate Cancer Consensus ConferenceAdvanced prostate cancerProstate cancerClinical managementLack high-level evidenceConsensus conferenceManagement of patientsHigh-level evidenceEvidence-based guidelinesModified Delphi processCancer characteristicsClinical evidenceClinical trialsImpact daily practiceTreatment decisionsWeb-based surveyConsensus questionsPC expertsPatientsMeta-analysisCancerDelphi processDaily practicePanel members
Clinical Care
Overview
William K. Oh, MD, is a genitourinary oncologist with decades of experience specializing in prostate cancer. He integrates molecular and genetic testing into routine cancer care, ensuring that patients receive the most personalized treatment plans possible. Throughout his career he has focused on decreasing barriers to the delivery of care for prostate cancer nationally.
Dr. Oh is the director of precision medicine at Yale Cancer Center and Smilow Cancer Hospital, where he leads efforts to develop cohesive programs that combine basic and translational science with clinical trials. He also oversees the Precision Medicine Tumor Board, which is pivotal in guiding treatment decisions based on genetic and molecular data. Additionally, he serves as the service line medical director of Smilow Cancer Hospital at Greenwich Hospital, where he continues to develop integrated oncology care teams and expand the impact of multidisciplinary cancer care for patients in the region.
Dr. Oh completed his undergraduate degree at Yale University, received his medical degree from New York University School of Medicine, and did his internship and residency at Brigham and Women’s Hospital before his clinical fellowship in medical oncology at Dana-Farber Cancer Institute.
Dr. Oh currently serves as chair of the American Cancer Society's National Prostate Cancer Roundtable, whose mission is to improve prostate cancer outcomes and survivorship through increasing awareness and equitable access to prevention, screening, and treatment. Also, he is the chair of the Medical Advisory Council for the Chemotherapy Foundation, which is committed to discovering novel therapies for cancer.
“I love taking care of patients because it brings me tremendous personal satisfaction to both help them and learn from them,” Dr. Oh says. “I also love the precision medicine part of my job, but in the end, my patient care responsibilities always bring me back to what it’s all about and why we’re all here and I enjoy getting to know my patients and their generosity of spirit and courage. I take a lot of lessons from that.”
Clinical Specialties
Fact Sheets
Prostate Cancer
Learn More on Yale MedicineUrologic Cancers
Learn More on Yale Medicine
Board Certifications
Medical Oncology
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 1998
Yale Medicine News
News & Links
Media
New Advances in Prostate Cancer in 2025
Yale Cancer Center Grand Rounds | January 21, 2025
Presented by: Dr. William Oh
News
- June 24, 2025Source: NBC Connecticut (with Dr. William Oh)
Raising awareness about early cancer detection
- June 06, 2025Source: ReachMD (With Dr. William Oh)
Why Words Matter: Rethinking Terminology in Advanced Prostate Cancer
- June 06, 2025
Yale Cancer Center Researchers and Trainees Present at 2025 ASCO Annual Meeting
- May 21, 2025Source: News 12 Connecticut
Conversation Connecticut: Dr. William K. Oh, Director of Precision Medicine for Yale Cancer Center Talks About Prostate Cancer
Get In Touch
Contacts
Yale Cancer Center
333 Cedar Street, PO Box 208028
New Haven, Connecticut 06520
United States
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Locations
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Events
Everyone Multi-session EventWilliam K. Oh, MD
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