Tae Oh, MD
Professor Emeritus of AnesthesiologyCards
About
Research
Publications
2024
Anti-neuroinflammatory effects of the KIOM -patented Polygonum multiflorum maximized root tuber against LPS-stimulated BV2 Cells
Oh T, Ban Y, Kang Y. Anti-neuroinflammatory effects of the KIOM -patented Polygonum multiflorum maximized root tuber against LPS-stimulated BV2 Cells. Applied Biological Chemistry 2024, 67: 71. DOI: 10.1186/s13765-024-00928-0.Peer-Reviewed Original ResearchHigher content of active ingredientP. multiflorumMouse microglial BV-2 cellsLPS-stimulated BV2 cellsContent of active ingredientsTranscription factor activityAnti-neuroinflammatory effectsMitogen-activated protein kinaseMechanisms of neurodegenerationActivation of p38Pathological mechanisms of neurodegenerationMicroglial BV-2 cellsHigher contentIncreased biomassRoot tubersBV2 cellsAntioxidant effectsCultivation conditionsProtein kinaseOriental medicinal herbRegulation mechanismBV-2 cellsInducible NO synthaseMAPK phosphorylationMedicinal herbsAntioxidant Efficacy of Hwangryunhaedok-tang through Nrf2 and AMPK Signaling Pathway against Neurological Disorders In Vivo and In Vitro
Bae S, Lee W, Bak S, Lee S, Hwang S, Kim G, Koo B, Park S, Yoo H, Kim C, Kang H, Oh T, Kim Y. Antioxidant Efficacy of Hwangryunhaedok-tang through Nrf2 and AMPK Signaling Pathway against Neurological Disorders In Vivo and In Vitro. International Journal Of Molecular Sciences 2024, 25: 2313. PMID: 38396988, PMCID: PMC10889506, DOI: 10.3390/ijms25042313.Peer-Reviewed Original ResearchConceptsFormation of neurofibrillary tanglesNeurofibrillary tanglesAlzheimer's diseaseImpaired clearance of amyloid betaSignaling pathwayClearance of amyloid betaAMPK signaling pathwayActivate signaling pathwaysAlzheimer's disease in vivoInhibition of cell apoptosisCause of dementiaAmyloid-betaHT-22 cellsNeuritic plaquesIn vitroMitochondrial dysfunctionOxidative stressCell apoptosisDisease in vivoROS generationHT-22Prevent ADAMPKDisorders in vivoProtein levels
2020
Acer tegmentosum Maxim Prevents Bone Loss by Inhibiting Osteoclastogenesis and Promoting Osteoblast Mineralization in Ovariectomized Mice
Oh T, Park K, Do H, Kim K, Yang H, Cho W, Ma J. Acer tegmentosum Maxim Prevents Bone Loss by Inhibiting Osteoclastogenesis and Promoting Osteoblast Mineralization in Ovariectomized Mice. Natural Product Sciences 2020, 26: 83-89. DOI: 10.20307/nps.2020.26.1.83.Peer-Reviewed Original Research