Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsSinan Guloksuz, MD, PhD
Associate Professor Adjunct in PsychiatryAbout
Research
Publications
2026
Sex differences in the effect of childhood adversity and coping strategies on psychosis expression: A TwinssCan study.
Karaçam Doğan M, Prachason T, Fusar-Poli L, Menne-Lothmann C, Decoster J, van Winkel R, Collip D, Delespaul P, De Hert M, Derom C, Thiery E, Jacobs N, Wichers M, Rutten B, van Os J, Pries L, Guloksuz S. Sex differences in the effect of childhood adversity and coping strategies on psychosis expression: A TwinssCan study. European Psychiatry 2026, 69: e42. PMID: 41714187, DOI: 10.1192/j.eurpsy.2026.10173.Peer-Reviewed Original ResearchConceptsChildhood adversityCoping strategiesSocial supportCommunity assessmentPsychosis expressionCommunity Assessment of Psychic ExperiencesCAPE scoresMixed linear regression analysesUtrecht Coping ListEffects of childhood adversityAdaptive coping strategiesSex-specific effectsEmotional neglectPhysical abuseReassuring thoughtsPhysical neglectSex differencesCoping stylesLinear regression analysisGeneral populationCoping mechanismsEmotional abuseAssociation of PESexual abuseChildhood Trauma QuestionnaireSituating problematic gaming and psychotic-like experiences in the adolescent landscape of affordances: A cohort study.
Paquin V, Lavallee Z, Huot-Lavoie M, Ku B, Díaz-Caneja C, Gülöksüz S. Situating problematic gaming and psychotic-like experiences in the adolescent landscape of affordances: A cohort study. Journal Of Behavioral Addictions 2026 PMID: 41586822, DOI: 10.1556/2006.2025.00094.Peer-Reviewed Original ResearchPsychotic-like experiencesFamily environmentProtect schoolsFamily environment variablesSchool environmentPositive schoolProblematic gamingSchoolDigital gamesLevels of psychotic-like experiencesPeer environmentAdolescent Brain Cognitive Development StudyAssociated with problematic gamingPeerAffordance theoryCognitive Development StudyLandscape of affordancesAssociated with lower levelsAssociated with higher levelsDevelopment studiesAffordabilityEnvironment variablesYouthPartial supportAntipsychotic plasma concentration as predictor of movement disorders and cardiometabolic side-effects: A comparison with prescription dose
Liu Y, Sommer I, Schoretsanitis G, Hamers I, Scheurink T, Begemann M, Gangadin S, van Beveren N, Consortium H, Sommer I, de Haan L, Veling W, van Os J, Smit F, Begemann M, Koops S, Marcelis M, Kikkert M, van Beveren N, Boonstra N, Rosema B, Bakker P, Gülöksüz S, Lokkerbol J, Wijnen B, Brand B, Gangadin S, van ’t H, Oomen P, Voppel A, de Beer F, Kamphuis S, Hamers I, Djordjevic M, Scheurink T, Noorman J, van Amelsvoort T, Bak M, Berendsen S, van den Brink T, Faber G, Grootens K, de Jonge M, Knegtering H, Kurkamp J, Pijnenborg G, Staring A, Veen N, Veerman S, Wiersma S, Batalla A, Curfs R, Hage J, Graveland E, Hoornaar J, Hobus I, Huizer K, Koops S, Bakker P. Antipsychotic plasma concentration as predictor of movement disorders and cardiometabolic side-effects: A comparison with prescription dose. European Neuropsychopharmacology 2026, 105: 112769. PMID: 41576855, DOI: 10.1016/j.euroneuro.2026.112769.Peer-Reviewed Original ResearchConceptsFirst-episode psychosisCardiometabolic side effectsFirst-episode psychosis patientsBarnes Akathisia Rating ScaleRating ScaleSt. Hans Rating ScaleMovement disordersTherapeutic drug monitoringAntipsychotic plasma concentrationsStriatal dopamine receptorsPrescription dosePlasma concentrationsSide effectsTardive dyskinesiaDopamine receptorsTardive dystoniaWaist circumferenceCardiometabolic indicesMedian 6-month follow-upLongitudinal associationsLow-density-lipoprotein cholesterolDisordersNon-high-density-lipoprotein cholesterolNon-high-density-lipoproteinBody mass indexSex differences in the independent and combined effects of genomic and exposomic risks for schizophrenia on distressing psychotic experiences: insights from the ABCD study
Prachason T, Arias-Magnasco A, Lin B, van Os J, Rutten B, Pries L, Guloksuz S. Sex differences in the independent and combined effects of genomic and exposomic risks for schizophrenia on distressing psychotic experiences: insights from the ABCD study. Archives Of Women's Mental Health 2026, 29: 7. PMID: 41493491, PMCID: PMC12775040, DOI: 10.1007/s00737-025-01644-4.Peer-Reviewed Original ResearchConceptsDistressing psychotic experiencesPsychotic experiencesPRS-SCZES-SCZEarly adolescenceSex differencesCognitive Development StudySex-dependent effectsJoint associationsAssociated with lifetimeAdolescent brainMultilevel logistic regression modelsABCD studyExposome scorePolygenic riskSchizophreniaSex-stratified analysesConclusionThe influenceSex-dependentLogistic regression modelsAdolescentsFollow-up dataGenomic riskSecondary outcomesPE outcomesGene-environment effects on psychotic experiences in adolescents: insights from the ALSPAC cohort
Magnasco A, Lin B, Pries L, Rutten B, Guloksuz S. Gene-environment effects on psychotic experiences in adolescents: insights from the ALSPAC cohort. Neuroscience Applied 2026, 5: 106409. DOI: 10.1016/j.nsa.2025.106409.Peer-Reviewed Original ResearchTesting the psychological protective mechanisms against psychosis expression in autism spectrum in a general population twin sample
Doğan M, Fusar-Poli L, Arias-Magnasco A, Pries L, Lin B, Klingenberg B, Bortoletto R, Colizzi M, Menne-Lothmann C, Decoster J, van Winkel R, Collip D, Delespaul P, De Hert M, Derom C, Thiery E, Jacobs N, van Os J, Rutten B, Luykx J, Prachason T, Guloksuz S. Testing the psychological protective mechanisms against psychosis expression in autism spectrum in a general population twin sample. Neuroscience Applied 2026, 5: 106498. DOI: 10.1016/j.nsa.2025.106498.Peer-Reviewed Original ResearchGender differences in the association between autistic traits and psychopathology in adolescents and young adults: Results from the TwinssCan cohort
Fusar-Poli L, Doğan M, Prachason T, Scalmati S, Investigators T, van Os J, Rutten B, Guloksuz S. Gender differences in the association between autistic traits and psychopathology in adolescents and young adults: Results from the TwinssCan cohort. Neuroscience Applied 2026, 5: 106310. DOI: 10.1016/j.nsa.2025.106310.Peer-Reviewed Original ResearchSex-dependent influences of genomic and exposomic liabilities for schizophrenia on psychotic experiences in early adolescence: evidence from the ABCD study
Prachason T, Arias-Magnasco A, Lin B, van Os J, Rutten B, Pries L, Guloksuz S. Sex-dependent influences of genomic and exposomic liabilities for schizophrenia on psychotic experiences in early adolescence: evidence from the ABCD study. Neuroscience Applied 2026, 5: 106425. DOI: 10.1016/j.nsa.2025.106425.Peer-Reviewed Original ResearchAssociations between healthy lifestyle, genetic risk for severe mental illness and resilience to incident somatic illness
Isayeva U, Guloksuz S, Lin B, De Boer N, Manchia M, Luykx J. Associations between healthy lifestyle, genetic risk for severe mental illness and resilience to incident somatic illness. Neuroscience Applied 2026, 5: 106826. DOI: 10.1016/j.nsa.2025.106826.Peer-Reviewed Original ResearchCommon component and psychiatric disorder specific polygenic risk score effects on emotional and behavioural trajectories in young people
Lin B, Prachason T, Pries L, Arias-Magnasco A, Rutten B, Guloksuz S. Common component and psychiatric disorder specific polygenic risk score effects on emotional and behavioural trajectories in young people. Neuroscience Applied 2026, 5: 105905. DOI: 10.1016/j.nsa.2025.105905.Peer-Reviewed Original Research