Sanjiv Neupane
he/him/his
Associate Research Scientist in GeneticsCards
About
Research
Publications
2026
Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants
Neupane S, Almiroudis A, Donnelly K, Haltiwanger R, Holdener B. Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants. Developmental Dynamics 2026 PMID: 42157385, DOI: 10.1002/dvdy.70148.Peer-Reviewed Original Research
2025
Modulation of Prickle2 Expression to Facilitate Dentine Formation: A Laboratory Investigation
Rana B, Neupane S, Aryal Y, Pokharel E, Kim T, Lee J, Jang J, Yamamoto H, Kim J, An S, An C, Jung J, Sohn W, Cho S, Ha J, Kim J. Modulation of Prickle2 Expression to Facilitate Dentine Formation: A Laboratory Investigation. International Endodontic Journal 2025, 58: 1902-1912. PMID: 40916368, DOI: 10.1111/iej.70024.Peer-Reviewed Original ResearchPOGLUT2/3 mediated EGF O-glucosylation promotes separation of digits 2 and 3 by influencing fibrillin network reorganization, signaling, and cell dynamics
Neupane S, Janowicz I, Godwin A, Donnelly K, Grady R, Haltiwanger R, Baldock C, Holdener B. POGLUT2/3 mediated EGF O-glucosylation promotes separation of digits 2 and 3 by influencing fibrillin network reorganization, signaling, and cell dynamics. Developmental Biology 2025, 527: 147-164. PMID: 40784523, PMCID: PMC13271073, DOI: 10.1016/j.ydbio.2025.08.004.Peer-Reviewed Original Research
2024
Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues
Neupane S, Williamson D, Roth R, Halabi C, Haltiwanger R, Holdener B. Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues. Journal Of Biological Chemistry 2024, 300: 107445. PMID: 38844137, PMCID: PMC11261140, DOI: 10.1016/j.jbc.2024.107445.Peer-Reviewed Original ResearchUnraveling the structure, chemical composition, and conserved signaling in leech teeth
Aryal Y, Neupane S, Kwak H, An C, Sohn W, Yamamoto H, Kwon T, Min B, Kim J, Cho S. Unraveling the structure, chemical composition, and conserved signaling in leech teeth. Animal Cells And Systems 2024, 28: 272-282. PMID: 38741948, PMCID: PMC11089927, DOI: 10.1080/19768354.2024.2350736.Peer-Reviewed Original ResearchProhibitin modulates periodontium differentiation in mice development
Aryal Y, Han S, Rana B, Neupane S, Kim T, Pokharel E, Ha J, Jung J, An C, Kim J, Yamamoto H, Lee Y, An S, Suh J, Kim J, Sohn W. Prohibitin modulates periodontium differentiation in mice development. Frontiers In Cell And Developmental Biology 2024, 12: 1369634. PMID: 38756696, PMCID: PMC11096493, DOI: 10.3389/fcell.2024.1369634.Peer-Reviewed Original Research
2023
Functional modulation of lysophosphatidic acid type 2 G‐protein coupled receptor facilitates alveolar bone formation
Kim T, Kim A, Aryal Y, Sung S, Pokharel E, Neupane S, Choi S, Ha J, Jung J, Yamamoto H, An C, Suh J, Sohn W, Lee Y, Jang I, Norman D, Tigyi G, An S, Kim J. Functional modulation of lysophosphatidic acid type 2 G‐protein coupled receptor facilitates alveolar bone formation. Journal Of Cellular Physiology 2023, 239: 112-123. PMID: 38149778, DOI: 10.1002/jcp.31148.Peer-Reviewed Original ResearchDevelopmental roles of glomerular epithelial protein-1 in mice molar morphogenesis
Neupane S, Aryal Y, Kwak H, Lee S, Kim T, Pokharel E, Kim J, Kim J, Sohn W, An S, An C, Jung J, Ha J, Yamamoto H, Cho S, Lee S, Lee Y, Park K, Min B, Park C, Kwon T, Cho S, Kim J. Developmental roles of glomerular epithelial protein-1 in mice molar morphogenesis. Cell And Tissue Research 2023, 395: 53-62. PMID: 37985496, DOI: 10.1007/s00441-023-03841-y.Peer-Reviewed Original ResearchO-fucosylation of thrombospondin type I repeats is dispensable for trafficking thrombospondin 1 to platelet secretory granules
Berardinelli S, Sillato A, Grady R, Neupane S, Ito A, Haltiwanger R, Holdener B. O-fucosylation of thrombospondin type I repeats is dispensable for trafficking thrombospondin 1 to platelet secretory granules. Glycobiology 2023, 33: 301-310. PMID: 36721988, PMCID: PMC10191222, DOI: 10.1093/glycob/cwad006.Peer-Reviewed Original Research
2022
O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development
Neupane S, Berardinelli S, Cameron D, Grady R, Komatsu D, Percival C, Takeuchi M, Ito A, Liu T, Nairn A, Moremen K, Haltiwanger R, Holdener B. O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development. Matrix Biology 2022, 107: 77-96. PMID: 35167946, PMCID: PMC9606722, DOI: 10.1016/j.matbio.2022.02.002.Peer-Reviewed Original Research