Robert Kleven, PhD, MD
Hospital ResidentCards
About
Research
Publications
2025
Percutaneous Radiologic Gastrostomy Tube Placement Techniques
Kleven R, Ikeda I, Cornman-Homonoff J. Percutaneous Radiologic Gastrostomy Tube Placement Techniques. Seminars In Interventional Radiology 2025, 42: 009-016. PMID: 40342381, PMCID: PMC12058293, DOI: 10.1055/s-0045-1806797.Peer-Reviewed Original ResearchBalloon-assisted techniqueProcedure timeRetrograde techniqueIncidence of tube dislodgementPercutaneous endoscopic gastrostomy placementPatient's clinical presentationShorter procedure timeReduce radiation exposurePostprocedural infectionClinical presentationTube dislodgementInterventional radiologistsDecreased incidenceGastrostomy placementGastrostomy tubeGastric accessAntegrade techniquePreprocedural workupRadiation exposureAntegradePatient-centered careRetrogradeCare helpWorkupPatientsPercutaneous Radiologic Gastrostomy Placement in Challenging Clinical Scenarios
Ikeda I, Kleven R, Cornman-Homonoff J. Percutaneous Radiologic Gastrostomy Placement in Challenging Clinical Scenarios. Seminars In Interventional Radiology 2025, 42: 017-021. PMID: 40342380, PMCID: PMC12058298, DOI: 10.1055/s-0045-1805046.Peer-Reviewed Original ResearchPercutaneous radiologic gastrostomy placementUpper gastrointestinal tract obstructionPercutaneous radiologic gastrostomyClinical management optionsIncreased procedural riskGastrointestinal tract obstructionRadiologic gastrostomyEnteral accessPostsurgical anatomyNutritional supportProcedural riskGastrostomy placementClinical scenariosTechnical modificationsMedication administrationPatientsManagement options
2023
Effect of Recombinant Tissue Plasminogen Activator and 120-kHz Ultrasound on Porcine Intracranial Thrombus Density.
Kleven RT, Huang S, Ford SM, Sakthivel K, Thomas SR, Zuccarello M, Herr AB, Holland CK. Effect of Recombinant Tissue Plasminogen Activator and 120-kHz Ultrasound on Porcine Intracranial Thrombus Density. Ultrasound Med Biol 2023, 49: 539-548. PMID: 36336551, DOI: 10.1016/j.ultrasmedbio.2022.10.006.Peer-Reviewed Original Research
2021
Accelerated sonothrombolysis with Definity in a xenographic porcine cerebral thromboembolism model.
Kleven RT, Karani KB, Hilvert N, Ford SM, Mercado-Shekhar KP, Racadio JM, Rao MB, Abruzzo TA, Holland CK. Accelerated sonothrombolysis with Definity in a xenographic porcine cerebral thromboembolism model. Sci Rep 2021, 11: 3987. PMID: 33597659, DOI: 10.1038/s41598-021-83442-3.Peer-Reviewed Original Research
2020
Ultrasound-Responsive Cavitation Nuclei for Therapy and Drug Delivery.
Kooiman K, Roovers S, Langeveld SAG, Kleven RT, Dewitte H, O'Reilly MA, Escoffre JM, Bouakaz A, Verweij MD, Hynynen K, Lentacker I, Stride E, Holland CK. Ultrasound-Responsive Cavitation Nuclei for Therapy and Drug Delivery. Ultrasound Med Biol 2020, 46: 1296-1325. PMID: 32165014, DOI: 10.1016/j.ultrasmedbio.2020.01.002.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2019
The effect of 220 kHz insonation scheme on rt-PA thrombolytic efficacy in vitro.
Kleven RT, Karani KB, Salido NG, Shekhar H, Haworth KJ, Mast TD, Tadesse DG, Holland CK. The effect of 220 kHz insonation scheme on rt-PA thrombolytic efficacy in vitro. Phys Med Biol 2019, 64: 165015. PMID: 31189149, DOI: 10.1088/1361-6560/ab293b.Peer-Reviewed Original ResearchIn vitro characterization of sonothrombolysis and echocontrast agents to treat ischemic stroke.
Shekhar H, Kleven RT, Peng T, Palaniappan A, Karani KB, Huang S, McPherson DD, Holland CK. In vitro characterization of sonothrombolysis and echocontrast agents to treat ischemic stroke. Sci Rep 2019, 9: 9902. PMID: 31289285, DOI: 10.1038/s41598-019-46112-z.Peer-Reviewed Original Research
2018
Effect of Clot Stiffness on Recombinant Tissue Plasminogen Activator Lytic Susceptibility in Vitro.
Mercado-Shekhar KP, Kleven RT, Aponte Rivera H, Lewis R, Karani KB, Vos HJ, Abruzzo TA, Haworth KJ, Holland CK. Effect of Clot Stiffness on Recombinant Tissue Plasminogen Activator Lytic Susceptibility in Vitro. Ultrasound Med Biol 2018, 44: 2710-2727. PMID: 30268531, DOI: 10.1016/j.ultrasmedbio.2018.08.005.Peer-Reviewed Original Research
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