Ralph Horwitz, MD
Professor Emeritus of Medicine (General Medicine)Cards
About
Research
Publications
2026
The health consequences of politically-induced trauma
Horwitz R. The health consequences of politically-induced trauma. PLOS Mental Health 2026, 3: e0000579. PMID: 41860841, PMCID: PMC13004349, DOI: 10.1371/journal.pmen.0000579.Peer-Reviewed Original ResearchBiology is the Dark Matter of Disease Pathogenesis
Horwitz R, Conroy A, Cullen M, Sim I. Biology is the Dark Matter of Disease Pathogenesis. The American Journal Of Medicine 2026 PMID: 41687948, DOI: 10.1016/j.amjmed.2026.01.045.Peer-Reviewed Original ResearchBiography as the Dark Matter of Treatment Response
Horwitz R, Conroy A, Cullen M, Sim I. Biography as the Dark Matter of Treatment Response. The American Journal Of Medicine 2026 PMID: 41666970, DOI: 10.1016/j.amjmed.2026.01.044.Peer-Reviewed Original ResearchThe Person–Population Paradox in Clinical Medicine
Horwitz R, Conroy A, Cullen M, Sim I. The Person–Population Paradox in Clinical Medicine. The American Journal Of Medicine 2026 PMID: 41666972, DOI: 10.1016/j.amjmed.2026.01.047.Peer-Reviewed Original ResearchReconceptualizing Obesity and the Modern Definition of Disease
Horwitz R, Hayes Conroy A, Cullen M, Sim I. Reconceptualizing Obesity and the Modern Definition of Disease. The American Journal Of Medicine 2026 PMID: 41662898, DOI: 10.1016/j.amjmed.2026.01.052.Peer-Reviewed Original Research
2025
The imperative of the person in personalized medicine
Horwitz R, Conroy A, Cullen M, Matory A, Singer B, Sim I. The imperative of the person in personalized medicine. Communications Medicine 2025, 5: 469. PMID: 41238826, PMCID: PMC12618932, DOI: 10.1038/s43856-025-01218-6.Peer-Reviewed Original ResearchBiosocial Variation in Treatment Response to GLP-1s: Implications for Clinical Care and Health Policy
Horwitz R, Otaka S, Conroy A, Cullen M, Matory A, Singer B, Sim I. Biosocial Variation in Treatment Response to GLP-1s: Implications for Clinical Care and Health Policy. The American Journal Of Medicine 2025, 138: 1346-1351. PMID: 40393609, DOI: 10.1016/j.amjmed.2025.05.016.Peer-Reviewed Original ResearchTreatment-resistant obesityTrajectory of obesityResponse to treatmentObesity-related disordersRandomized Controlled TrialsReal-world evidence studiesTreatment responseClinical managementEvidence studiesGLP-1sControlled TrialsPatientsObesityWeight lossBody weightPathogenesisAverage treatment responseHealth policyTreatmentPhysiological systems
2024
Integrating biology and biography in medicine: The mind and body are not separate
Horwitz R, Cullen M, Conroy A, Sim I, Singer B, Badal K, Offidani E. Integrating biology and biography in medicine: The mind and body are not separate. PLOS Mental Health 2024, 1: e0000122. PMID: 41661880, PMCID: PMC12798616, DOI: 10.1371/journal.pmen.0000122.Peer-Reviewed Original ResearchPatient expectations are a feature of treatment strategy rather than a source of bias
Horwitz R, Baker J, Cullen M. Patient expectations are a feature of treatment strategy rather than a source of bias. PLOS Mental Health 2024, 1: e0000115. PMID: 41661774, PMCID: PMC12798560, DOI: 10.1371/journal.pmen.0000115.Peer-Reviewed Original ResearchBiosocial Medicine
Horwitz R, Cullen M. Biosocial Medicine. 2024, 150-159. DOI: 10.1201/9781003409373-20.Peer-Reviewed Original Research
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