Ralph Horwitz, MD
Professor Emeritus of Medicine (General Medicine)Cards
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Research
Publications
2025
Biosocial Variation in Treatment Response to GLP-1s: Implications for Clinical Care and Health Policy
Horwitz R, Otaka S, Conroy A, Cullen M, Matory A, Singer B, Sim I. Biosocial Variation in Treatment Response to GLP-1s: Implications for Clinical Care and Health Policy. The American Journal Of Medicine 2025, 138: 1346-1351. PMID: 40393609, DOI: 10.1016/j.amjmed.2025.05.016.Peer-Reviewed Original ResearchTreatment-resistant obesityTrajectory of obesityResponse to treatmentObesity-related disordersRandomized Controlled TrialsReal-world evidence studiesTreatment responseClinical managementEvidence studiesGLP-1sControlled TrialsPatientsObesityWeight lossBody weightPathogenesisAverage treatment responseHealth policyTreatmentPhysiological systems
2024
Integrating biology and biography in medicine: The mind and body are not separate
Horwitz R, Cullen M, Hayes Conroy A, Sim I, Singer B, Badal K, Offidani E. Integrating biology and biography in medicine: The mind and body are not separate. PLOS Mental Health 2024, 1: e0000122. DOI: 10.1371/journal.pmen.0000122.Peer-Reviewed Original ResearchPatient expectations are a feature of treatment strategy rather than a source of bias
Horwitz R, Baker J, Cullen M. Patient expectations are a feature of treatment strategy rather than a source of bias. PLOS Mental Health 2024, 1: e0000115. DOI: 10.1371/journal.pmen.0000115.Peer-Reviewed Original ResearchRandomization Bias, Multi-Morbidity, and the Composite Clinical Score
Horwitz R, Baker J, Ghatak A, Cullen M. Randomization Bias, Multi-Morbidity, and the Composite Clinical Score. Psychotherapy And Psychosomatics 2024, 93: 219-223. PMID: 38889693, DOI: 10.1159/000539522.Peer-Reviewed Original ResearchClinical Interviewing: An Essential but Neglected Method of Medicine
Fava G, Sonino N, Aron D, Balon R, Montiel C, Cao J, Concato J, Eory A, Horwitz R, Rafanelli C, Schnyder U, Wang H, Wise T, Wright J, Zipfel S, Patierno C. Clinical Interviewing: An Essential but Neglected Method of Medicine. Psychotherapy And Psychosomatics 2024, 93: 94-99. PMID: 38382481, DOI: 10.1159/000536490.Peer-Reviewed Original ResearchClinical InterviewIncrease patient motivationHealthy behaviorsMethods of medicineSelf-ManagementClinical encountersPatient motivationClinical processesPatient informationQuality of interviewsEducational trainingLack cost effectivenessClinical domainsPresenting complaintMedical historyInterviewsPhysiciansLife settingsTime pressureQuality of dataPersonal attitudesPatientsCost-effectiveExpensive testsDecision making
2023
Clinimetrics and Allostatic Load
Horwitz R, Singer B. Clinimetrics and Allostatic Load. Psychotherapy And Psychosomatics 2023, 92: 283-286. PMID: 37883947, DOI: 10.1159/000534257.Peer-Reviewed Original ResearchBiology Is Not Destiny
Horwitz R, Cullen M. Biology Is Not Destiny. Psychotherapy And Psychosomatics 2023, 92: 205-207. PMID: 37619544, PMCID: PMC10614434, DOI: 10.1159/000533449.Peer-Reviewed Original Research
1988
Choosing cases and controls: the clinical epidemiology of "clinical investigation".
Feinstein A, Horwitz R. Choosing cases and controls: the clinical epidemiology of "clinical investigation". Journal Of Clinical Investigation 1988, 81: 1-5. PMID: 3275691, PMCID: PMC442465, DOI: 10.1172/jci113279.Peer-Reviewed Original Research
1987
A reappraisal of the United Kingdom epidemic of fatal asthma. Can general mortality data implicate a therapeutic agent?
Esdaile J, Feinstein A, Horwitz R. A reappraisal of the United Kingdom epidemic of fatal asthma. Can general mortality data implicate a therapeutic agent? JAMA Internal Medicine 1987, 147: 543-9. PMID: 3827432, DOI: 10.1001/archinte.147.3.543.Peer-Reviewed Original ResearchConceptsAsthma deathsMortality dataEpidemic of asthma deathsInternational mortality dataScientific evidenceNonprescription salesYoung personAffecting young personsAsthmaUnited KingdomFatal asthmaEcological studiesNonprescriptionOriginal associationNew ZealandDeathEpidemicAerosolized bronchodilatorsBronchodilatorUnitsAssociationWales
1984
Case-control research. Temporal precedence and other problems of the exposure-disease relationship.
Horwitz R, Feinstein A, Harvey M. Case-control research. Temporal precedence and other problems of the exposure-disease relationship. JAMA Internal Medicine 1984, 144: 1257-9. PMID: 6732381, DOI: 10.1001/archinte.144.6.1257.Peer-Reviewed Original Research
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