Qiao Wu
Associate Research Scientist in Cell BiologyCards
About
Research
Publications
2023
Serum Response Factor Reduces Gene Expression Noise and Confers Cell State Stability
Zhang J, Wu Q, Hu X, Wang Y, Lu J, Martin K, Guo S. Serum Response Factor Reduces Gene Expression Noise and Confers Cell State Stability. Stem Cells 2023, 41: 907-915. PMID: 37386941, PMCID: PMC11009695, DOI: 10.1093/stmcls/sxad051.Peer-Reviewed Original Research
2021
Acetylation of KLF5 maintains EMT and tumorigenicity to cause chemoresistant bone metastasis in prostate cancer
Zhang B, Li Y, Wu Q, Xie L, Barwick B, Fu C, Li X, Wu D, Xia S, Chen J, Qian W, Yang L, Osunkoya A, Boise L, Vertino P, Zhao Y, Li M, Chen H, Kowalski J, Kucuk O, Zhou W, Dong J. Acetylation of KLF5 maintains EMT and tumorigenicity to cause chemoresistant bone metastasis in prostate cancer. Nature Communications 2021, 12: 1714. PMID: 33731701, PMCID: PMC7969754, DOI: 10.1038/s41467-021-21976-w.Peer-Reviewed Original ResearchAcetylationAnimalsAntineoplastic Combined Chemotherapy ProtocolsBenzylaminesBone NeoplasmsCarcinogenesisCell Line, TumorCyclamsDocetaxelEpithelial-Mesenchymal TransitionHumansInterleukin-11Kruppel-Like Transcription FactorsMaleMiceMutationOsteogenesisProstatic Neoplasms, Castration-ResistantReceptors, CXCR4Signal TransductionTransforming Growth Factor beta
2020
Reprogramming progressive cells display low CAG promoter activity
Hu X, Wu Q, Zhang J, Kim J, Chen X, Hartman AA, Eastman AE, Park I, Guo S. Reprogramming progressive cells display low CAG promoter activity. Stem Cells 2020, 39: 43-54. PMID: 33075202, PMCID: PMC7821215, DOI: 10.1002/stem.3295.Peer-Reviewed Original Research
2018
CINP is a novel cofactor of KLF5 required for its role in the promotion of cell proliferation, survival and tumor growth
Wu Q, Fu C, Li M, Li J, Li Z, Qi L, Ci X, Ma G, Gao A, Fu X, A J, An N, Liu M, Li Y, King JL, Fu L, Zhang B, Dong JT. CINP is a novel cofactor of KLF5 required for its role in the promotion of cell proliferation, survival and tumor growth. International Journal Of Cancer 2018, 144: 582-594. PMID: 30289973, PMCID: PMC6294659, DOI: 10.1002/ijc.31908.Peer-Reviewed Original ResearchLEM4 confers tamoxifen resistance to breast cancer cells by activating cyclin D-CDK4/6-Rb and ERα pathway
Gao A, Sun T, Ma G, Cao J, Hu Q, Chen L, Wang Y, Wang Q, Sun J, Wu R, Wu Q, Zhou J, Liu L, Hu J, Dong J, Zhu Z. LEM4 confers tamoxifen resistance to breast cancer cells by activating cyclin D-CDK4/6-Rb and ERα pathway. Nature Communications 2018, 9: 4180. PMID: 30301939, PMCID: PMC6177406, DOI: 10.1038/s41467-018-06309-8.Peer-Reviewed Original ResearchAnimalsAurora Kinase ABreast NeoplasmsCarcinogenesisCell Line, TumorCell ProliferationCyclin DCyclin-Dependent KinasesDrug Resistance, NeoplasmEstrogen Receptor alphaFemaleG1 PhaseHumansMembrane ProteinsMice, NudeNuclear ProteinsPhosphorylationProtein BindingProtein StabilityRetinoblastoma ProteinS PhaseSignal TransductionSurvival AnalysisTamoxifenTranscriptional ActivationTreatment Outcome
2017
ERRF sensitizes ERBB2-positive breast cancer cells to lapatinib treatment likely by attenuating MCL1 and ERBB2 expression
Qi L, Zhang B, Zhang S, Ci X, Wu Q, Ma G, Luo A, Fu L, King J, Nahta R, Dong J. ERRF sensitizes ERBB2-positive breast cancer cells to lapatinib treatment likely by attenuating MCL1 and ERBB2 expression. Oncotarget 2017, 5: 36054-36066. PMID: 28415602, PMCID: PMC5482638, DOI: 10.18632/oncotarget.16425.Peer-Reviewed Original ResearchAnimalsAntineoplastic AgentsApoptosisBreast NeoplasmsCell Line, TumorDrug Resistance, NeoplasmErbB ReceptorsFemaleGene Expression Regulation, NeoplasticHumansLapatinibMiceMice, Inbred BALB CMice, NudeMyeloid Cell Leukemia Sequence 1 ProteinNuclear ProteinsQuinazolinesReceptor, ErbB-2RNA, Small InterferingSignal TransductionSurvival AnalysisXenograft Model Antitumor Assays
2015
Maize reas1 Mutant Stimulates Ribosome Use Efficiency and Triggers Distinct Transcriptional and Translational Responses
Qi W, Zhu J, Wu Q, Wang Q, Li X, Yao D, Jin Y, Wang G, Wang G, Song R. Maize reas1 Mutant Stimulates Ribosome Use Efficiency and Triggers Distinct Transcriptional and Translational Responses. Plant Physiology 2015, 170: 971-988. PMID: 26645456, PMCID: PMC4734584, DOI: 10.1104/pp.15.01722.Peer-Reviewed Original Research
2014
Characterization of the Promoter of a Homolog of Maize MADS-Box Gene m18
QIN H, Hong P, FAN X, Qiao W, LI Y. Characterization of the Promoter of a Homolog of Maize MADS-Box Gene m18. Journal Of Integrative Agriculture 2014, 13: 2330-2345. DOI: 10.1016/s2095-3119(13)60677-2.Peer-Reviewed Original ResearchExistence of abiotic stress-responsive genes within the regions of QTLs controlling maize grain yield: One of the root causes for unstability of the QTLs?
Wu Q, Shu P, Cai T, Fan X, Li Y. Existence of abiotic stress-responsive genes within the regions of QTLs controlling maize grain yield: One of the root causes for unstability of the QTLs? South African Journal Of Botany 2014, 93: 231-241. DOI: 10.1016/j.sajb.2014.03.020.Peer-Reviewed Original ResearchInterruption of KLF5 acetylation converts its function from tumor suppressor to tumor promoter in prostate cancer cells
Li X, Zhang B, Wu Q, Ci X, Zhao R, Zhang Z, Xia S, Su D, Chen J, Ma G, Fu L, Dong J. Interruption of KLF5 acetylation converts its function from tumor suppressor to tumor promoter in prostate cancer cells. International Journal Of Cancer 2014, 136: 536-546. PMID: 24931571, PMCID: PMC4232457, DOI: 10.1002/ijc.29028.Peer-Reviewed Original Research
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