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Hospital Resident
Biography
Mahesh Krishna graduated from Rice University in 2020 with a BA in Biochemistry and Cell Biology as well as Policy Studies and won multiple awards during his time in undergraduate including recognition as an Early Career Investigator from the American Gastroenterological Association, Excellence in Academic Advising Award, Cum Laude, Distinction in Research and Creative Work, and the 2020 Award for Excellence in Medical Research from the Rice Alumni in Medicine Society. He completed his medical degree at Johns Hopkins in 2024 and was elected to Alpha Omega Alpha. He has published 14 peer-reviewed manuscripts in reputable journals such as Inflammatory Bowel Diseases, Clinical Gastroenterology and Hepatology, and Journal of Autoimmunity. Six of these publications have been as first author with his research on Lactobacillus reuteri as a potential probiotic in maternal mice to prevent inflammatory bowel disease in offspring being cited in the recent "Global Consensus Statement on the Management of Pregnancy in Inflammatory Bowel Disease."
He is a current internal medicine resident at Yale and hopes to pursue a career as a physician-scientist.
Departments & Organizations
Education & Training
- MD
- Johns Hopkins University School of Medicine (2024)
- BA
- Rice University, Biochemistry and Cell Biology, Policy Studies
Research
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Overview
Mahesh Krishna is a current internal medicine resident who is interested in gastroenterology and hepatology. He wants to pursue a career as a physician-scientist who studies modifying the gut-liver axis and the immune system to treat primary sclerosing cholangitis-inflammatory bowel disease (PSC-IBD). He is currently actively involved in research projects on the impact of genetic polymorphisms in bile acid glucuronidation on cholestatic liver diseases as well as fenofibrate on PSC-IBD.
Public Health Interests
ORCID
0000-0001-9762-5717
Research at a Glance
Yale Co-Authors
Publications Timeline
Sowmya Sharma, MD
James Lorenzen Boyer, MD, FACEP, FAASLD, FAPS
Publications
2026
Featured Cover
Krishna M, Boyer J. Featured Cover. Liver International 2026, 46 DOI: 10.1111/liv.70565.Peer-Reviewed Original ResearchAltmetricIleal Bile Acid Transporter Inhibitors in Cholestasis: Potential for More Than Just Paediatrics?
Krishna M, Boyer J. Ileal Bile Acid Transporter Inhibitors in Cholestasis: Potential for More Than Just Paediatrics? Liver International 2026, 46: e70524. PMID: 41645895, DOI: 10.1111/liv.70524.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitations
2025
Incidence of Anti-Drug Antibody Development in Older Adults with Inflammatory Bowel Disease Treated with Tumor Necrosis Factor Alpha Inhibitors: A Large Multicenter Cohort Study
Frost S, Ambastha C, Patel D, Roney A, Greb A, Rangel-Garcia M, Sauk J, Chang C, Park S, Parian A, Suchan A, Moughames E, Krishna M, Chowdhury R, Sharma S, Maas L, Ho A, Lazarev M, Limketkai B, Limsui D, Keyashian K. Incidence of Anti-Drug Antibody Development in Older Adults with Inflammatory Bowel Disease Treated with Tumor Necrosis Factor Alpha Inhibitors: A Large Multicenter Cohort Study. Inflammatory Bowel Diseases 2025, 31: 3356-3362. PMID: 40971840, DOI: 10.1093/ibd/izaf170.Peer-Reviewed Original ResearchCitationsRetrospective Cohort Study on the Predictive Value of Primary Non-response to Initial Biologic for Future Biologic Use in Patients with Inflammatory Bowel Disease
Krishna M, Spartz E, Maas L, Cusumano V, Sharma S, Limketkai B, Parian A. Retrospective Cohort Study on the Predictive Value of Primary Non-response to Initial Biologic for Future Biologic Use in Patients with Inflammatory Bowel Disease. Digestive Diseases And Sciences 2025, 70: 746-753. PMID: 39755922, DOI: 10.1007/s10620-024-08816-9.Peer-Reviewed Original ResearchCitations
2023
Stochasticity Driven Limitations for Counseling in Autoimmune Gastrointestinal Disease
Philip A, Krishna M, Kellermayer R. Stochasticity Driven Limitations for Counseling in Autoimmune Gastrointestinal Disease. Journal Of Pediatric Gastroenterology And Nutrition 2023, 77: 695-697. PMID: 37779233, DOI: 10.1097/mpg.0000000000003955.Peer-Reviewed Original ResearchCitationsAltmetricSuperior Efficacy of Infliximab Versus Adalimumab for First-Line Treatment of Crohn’s Perianal Fistulae
Maas L, Gao R, Cusumano V, Spartz E, Chowdhury R, Krishna M, Lazarev M, Melia J, Selaru F, Sharma S, Limketkai B, Parian A. Superior Efficacy of Infliximab Versus Adalimumab for First-Line Treatment of Crohn’s Perianal Fistulae. Digestive Diseases And Sciences 2023, 68: 3994-4000. PMID: 37540392, DOI: 10.1007/s10620-023-08060-7.Peer-Reviewed Original ResearchCitationsAltmetricMachine Learning-based Characterization of Longitudinal Health Care Utilization Among Patients With Inflammatory Bowel Diseases
Limketkai B, Maas L, Krishna M, Dua A, DeDecker L, Sauk J, Parian A. Machine Learning-based Characterization of Longitudinal Health Care Utilization Among Patients With Inflammatory Bowel Diseases. Inflammatory Bowel Diseases 2023, 30: 697-703. PMID: 37454280, PMCID: PMC11491632, DOI: 10.1093/ibd/izad127.Peer-Reviewed Original ResearchCitationsAltmetricLetter: fulminant‐onset complicated inflammatory bowel disease (IBD)—a unique subtype?
Szigeti R, Krishna M, Kellermayer R. Letter: fulminant‐onset complicated inflammatory bowel disease (IBD)—a unique subtype? Alimentary Pharmacology & Therapeutics 2023, 57: 1192-1193. PMID: 37094325, DOI: 10.1111/apt.17418.Commentaries, Editorials and LettersCitations
2022
Dietary Interventions for the Treatment of Inflammatory Bowel Diseases: An Updated Systematic Review and Meta-analysis
Limketkai B, Godoy-Brewer G, Parian A, Noorian S, Krishna M, Shah N, White J, Mullin G. Dietary Interventions for the Treatment of Inflammatory Bowel Diseases: An Updated Systematic Review and Meta-analysis. Clinical Gastroenterology And Hepatology 2022, 21: 2508-2525.e10. PMID: 36470529, DOI: 10.1016/j.cgh.2022.11.026.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetricIroning It All Out: A Comprehensive Review of Iron Deficiency Anemia in Inflammatory Bowel Disease Patients
Maas L, Krishna M, Parian A. Ironing It All Out: A Comprehensive Review of Iron Deficiency Anemia in Inflammatory Bowel Disease Patients. Digestive Diseases And Sciences 2022, 68: 357-369. PMID: 35930123, DOI: 10.1007/s10620-022-07599-1.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetric
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